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1.
Maarit Vesterinen Hellevi Ruokonen Jussi Furuholm Eero Honkanen Jukka H. Meurman 《Clinical oral investigations》2011,15(1):99-104
We investigated oral health of chronic kidney disease (CKD) patients at predialysis state. The hypothesis was that diabetic
nephropathy affects oral health more detrimentally than other CKD patients due to the known risk diabetes presents in this
regard. We expected worse oral health and particularly poor periodontal health among the diabetic patients. A cross-sectional
study was conducted in the Helsinki University Central Hospital, Finland, on 148 patients with different kinds of kidney disease
at predialysis state. Data from medical records, clinical oral examination, saliva, and mucosal yeast counts were analyzed
and compared between the disease groups. Of the patients, 53 (36%) had diabetic nephropathy (29 patients with type 1, 24 patients
with type 2 diabetes). Compared with other CKD patients, diabetic patients had poor glycemic control as expected (mean HbA1C 8.0% vs 5.9%, p < 0.01). Diabetic patients also had more dental caries (mean number of carious teeth 5.1 vs 3.1, p < 0.01) and lower salivary flow rates than other CKD patients (stimulated salivary flow 1.2 ml/min vs 1.6 ml/min, p < 0.05). No difference between groups was observed in periodontal health and yeast counts. In conclusion, diabetic nephropathy
patients indeed had worse dental health in comparison to CKD group. However, contrary to our expectation, diabetic nephropathy
did not seem to affect periodontal health more severely than the other kidney diseases. 相似文献
2.
Hellevi Ruokonen Karita Nylund Jussi Furuholm Jukka H. Meurman Timo Sorsa Karoliina Kotaniemi Fernanda Ortiz Anna Maria Heikkinen 《Journal of periodontology》2017,88(1):26-33
Background: Factors related to mortality of patients with chronic kidney disease (CKD) were investigated to find out whether oral disease inflammatory burden or different etiology (diabetes nephropathy vs. other etiologies) of CKD could be associated with mortality. Methods: This prospective cohort study comprised 144 adults at the predialysis stage. Clinical oral and radiologic examination was made from 2000 to 2005. Patients were followed up until August 2015 (complete follow‐up time: 157 months). Cause of death could be verified from 62 of 65 patients. Clinical health data were combined with mortality records obtained from the Finland national statistics database. Number of teeth, total dental index (TDI), and periodontal inflammatory burden index were calculated to describe degree of oral inflammation. Results: Primary causes of death were cardiovascular diseases, infection, and cancer. There was a statistically significant difference in survival between diabetic nephropathy (23.8%) and other patients with CKD (59.9%; log‐rank test P <0.001). A Cox regression model showed fewer teeth, higher age, and diabetes mellitus were statistically significant independent risk factors for death. Deceased patients had fewer teeth (P <0.001) and higher TDI (P <0.05). Conclusions: Risk of death was higher among patients with diabetic nephropathy. The deceased had fewer teeth and more oral infections. However, indices used failed to show independent association with survival. 相似文献
3.
Association of the salivary triggering receptor expressed on myeloid cells/its ligand peptidoglycan recognition protein 1 axis with oral inflammation in kidney disease
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Karita M. Nylund Hellevi Ruokonen Timo Sorsa Anna Maria Heikkinen Jukka H. Meurman Fernanda Ortiz Taina Tervahartiala Jussi Furuholm Nagihan Bostanci 《Journal of periodontology》2018,89(1):117-129
1 Background
Triggering receptor expressed on myeloid cells (TREM‐1) is a cell‐surface receptor involved in amplification of inflammatory response to bacterial infections, along with its ligand peptidoglycan recognition protein 1 (PGLYRP1). TREM‐1 is shed by matrix metalloproteinases (MMPs) to its soluble (s) form. The aim of the study is to investigate association of sTREM‐1 and PGLYRP1 with oral inflammatory burden among patients with chronic kidney disease (CKD) at predialysis and posttransplantation stages.2 Methods
One hundred forty‐four patients with CKD were examined at predialysis, and oral infection foci were treated prior to kidney transplantation. Fifty‐three patients were available for follow‐up after transplantation. Oral inflammatory burden was assessed by the Periodontal Inflammatory Burden Index (PIBI) and Total Dental Index. sTREM‐1, PGLYRP1, and interleukin (IL)‐1β were measured in saliva by enzyme‐linked immunosorbent assay, and MMP‐8 was measured by immunofluorometric assay.3 Results
In the predialysis stage, sTREM‐1 and PGLYRP1 were positively associated with IL‐1β, MMP‐8, and PIBI. More specifically, patients with deeper probing depth (PD) (at least two sites with ≥6 mm) had higher concentrations of salivary sTREM‐1 and PGLYRP1 compared with those with shallower PD. Higher concentrations of PGLYRP1 and IL‐1β were associated with a higher number of teeth (> 25). On follow‐up, higher PGLYRP1 and sTREM‐1 were associated with one or more sites with ≥4 mm PD.4 Conclusions
sTREM‐1 and PGLYRP1 are elevated in patients with CKD with poor oral health and positively correlate with number of active periodontal pockets after oral infection therapy. Moreover, they positively correlate with MMP‐8 and IL‐1β. Hence, the salivary sTREM‐1/PGLYRP1 axis could be useful as a diagnostic marker for oral infection within patients with CKD. 相似文献4.
The aim was to study oral health status, salivary function, and oral features of Chinese people with Systemic Sclerosis (SSc).
Chinese people with SSc attending a university specialist clinic were invited for a questionnaire survey and a clinical examination.
Ethics approval was sought (UW 08-305). Gender- and age-matched individuals without SSc who attended a university dental hospital
were recruited for comparison. Forty-two SSc patients with a mean age of 54.0 ± 12.2 were examined. This study found no Chinese
people with systemic sclerosis were periodontally healthy and many (76%) had periodontal pockets despite most of them (93%)
practiced daily tooth-brushing. They all had caries experience (DMFT = 10.5) and many (65%) had untreated decay. Mucosal telangiectasia
was a common oral feature (80%). They had lower resting salivary flow rates (0.18 ± 0.17 ml/min vs. 0.31 ± 0.21 ml/min; p = 0.003) and pH values (6.90 ± 0.40 vs. 7.28 ± 0.31; p < 0.001) and reduced maximal mouth opening (40.1 ± 6.5 mm vs. 43.6 ± 7.0 mm) than people without SSc. 相似文献
5.
Tirwomwe JF Rwenyonyi CM Muwazi LM Besigye B Mboli F 《Clinical oral investigations》2007,11(3):289-292
The objective of the study is to establish the prevalence of oral manifestations and their influence on oral functions. A
total of 514 subjects aged 18 to 58 years (mean 42 years) were randomly recruited from five The AIDS Support Organization
(TASO) clinics in Uganda. They were clinically examined for oral lesions under field conditions by four trained dentists based
on World Health Organization criteria. Women constituted 74.5% of the study population. Oral manifestations were recorded
in 72% of the subjects, out of which 70% had candidiasis of pseudomembranous, erythematous, and angular cheilitis variants.
Non-Hodgkin’s lymphoma, atypical ulcers, necrotizing periodontitis, and hairy leucoplakia were least frequently observed in
the subjects. Of those who had oral lesions (n = 370), 68.4% had some form of discomfort in the mouth. Tooth brushing, chewing, and swallowing were frequently associated
with discomfort. Reported forms of discomfort were dry mouth, increased salivation, and burning sensation especially on taking
salty and spicy foods or acidic drinks. Only 8.5% (n = 44) of the subjects were taking medications specifically for oral lesions, which included antifungal, antiviral, and antibacterial
agents. None of the subjects were on antiretroviral therapy. Oral lesions associated with human immunodeficiency virus/acquired
immunodeficiency syndrome in TASO clients is a major public health problem requiring education in recognition and appropriate
management. 相似文献
6.
Chronic kidney disease (CKD) is a debilitating systemic condition. Our working hypothesis is that CKD predialysis patients with periodontitis would respond poorly to periodontal treatment owing to immunologic compromise. Twenty-one predialysis patients (group 1) and 19 individuals without clinical evidence of kidney disease (group 2) with chronic periodontitis were subjected to non-surgical periodontal treatment with no antibiotics. Clinical periodontal and systemic parameters were evaluated at baseline and 3 months after treatment. Both groups showed significant and similar post-treatment improvements in all periodontal parameters examined. Most interestingly, periodontal treatment had a statistically significant positive effect on the glomerular filtration rate of each individual (group 1, p = 0.04; group 2, p = 0.002). Our results indicate that chronic periodontitis in predialysis kidney disease patients improved similarly in patients with chronic periodontitis and no history of CKD after receiving non-surgical periodontal therapy. This study demonstrates that CKD predialysis patients show a good response to non-surgical periodontal treatment. 相似文献
7.
Mohit Sharma Indira Bairy Keerthilatha Pai Kapaettu Satyamoorthy Shailendra Prasad Barry Berkovitz Raghu Radhakrishnan 《Clinical oral investigations》2011,15(5):705-714
The development of oral cancer proceeds through discrete molecular changes that are acquired from loss of genomic integrity
after continued exposure to environmental risk factors. It is preceded in the majority of cases by clinically evident oral
potentially malignant disorders, the most common of which is leukoplakia. Early detection of these oral lesions by screening
methods using suitable markers is critical as it mirrors molecular alterations, long before cancer phenotypes are manifested.
Assessment of salivary interleukin-6 (IL-6) as a marker of malignant progression was undertaken in patients with leukoplakia
having coexisting periodontitis (n = 20), periodontitis patients without leukoplakia (n = 20), and healthy controls (n = 20) by competitive enzyme-linked immunosorbent assay. Results showed elevation of IL-6 levels in leukoplakia with coexisting
periodontitis and in periodontitis patients when compared to healthy control (P < 0.001). Within the leukoplakia group, IL-6 level was found to be increased with increase in the severity of dysplasia.
The use of tobacco was seen to play a significant role in the elevation of salivary IL-6.The importance of IL-6 as a specific
marker for leukoplakia with dysplasia and the role of tobacco as an independent risk factor has been highlighted. 相似文献
8.
Heikkinen AM Pitkäniemi J Kari K Pajukanta R Elonheimo O Koskenvuo M Meurman JH 《Clinical oral investigations》2012,16(2):571-580
The aim of our study was to investigate how teenage smoking affects the prevalence of periodontal bacteria and periodontal
health with the hypothesis that smoking increases the prevalence of the bacteria. Oral health of 264 adolescents (15- to 16-year-olds)
was clinically examined, and their smoking history was recorded. The participants also filled in a structured questionnaire
recording their general health and health habits. Pooled subgingival plaque samples were taken for polymerase chain reaction
analysis of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Prevotella nigrescens, and Treponema denticola. The prevalence of P. intermedia (21% vs. 4%, p = 0.01) and T. forsythia and T. denticola (23% vs. 8%, p < 0.05, for both) was higher among female smokers than among non-smokers. T. forsythia and T. denticola were more often associated with bleeding on probing (29% vs. 12%; 25% vs. 10%, respectively) and deep pockets (25% vs. 15%;
23% vs. 10%, respectively) with smokers than non-smokers. Among the girls, a significant association was found between pack-years
and the prevalence of P. nigrescens (p < 0.007). In both genders, A. actinomycetemcomitans and P. gingivalis were rare in this study. To conclude, periodontal bacteria were associated with higher periodontal index scores among all
teenage smokers. Smoking girls harbored more frequently certain periodontal bacteria than non-smokers, but this was not seen
in boys. Hence, our study hypothesis was only partly confirmed. 相似文献
9.
The purpose of this study was to assess the degree of pain during periodontal probing and mechanical non-surgical therapy
according to age, gender, and intersubject variation such as tooth type, tooth surfaces or regions of mouth, probing depth,
and bleeding on probing. The study was carried out on 64 patients with chronic periodontitis. Pain/discomfort of patients
during both periodontal probing and scaling and root planing (SRP) was measured using a visual analog scale (VAS). During
periodontal probing and SRP, VAS scores decreased with increasing age for two procedures (Spearman ρ, −0.301 and −0.348, respectively; P < 0.01). VAS scores were considerably lower for oral sites than for facial sites. VAS scores in probing were significantly
higher in sites ≥4 mm deep than sites <4 mm deep. Sites bleeding on probing had a significantly higher VAS scores than sites
no bleeding on probing (p < 0.05). The results showed that although there is no difference between genders, the intensity of pain during periodontal
probing and SRP was different dramatically between patients as well as vary between different locations in the same mouth.
If pain responses for probing in different several regions in the same mouth during initial examination were noted into patient
chart used for initial examination, the therapist will recognize patients with elevated pain responses. If need be, they will
then apply some pain control medication or anesthetic for patients during probing and SRP. 相似文献
10.
Soban Qadir Khan Abdul Khabeer Ahmad M. Al-Thobity Mashael Abdullah Benrashed Nujood Ibrahim Alyousef Yara AlMaimouni 《Saudi Dental Journal》2021,33(3):131-136
AimThis study aimed to evaluate the prevalence of carious, restored, and missing teeth among diabetic and non-diabetic patients who visited dental clinics in Dammam, Saudi Arabia.MethodThis retrospective study was conducted between April and November 2018. The data collection procedure was conducted in two steps: (1) review of patient records for the demographic variables and (2) screening of digital panoramic radiographs (OPGs). The patients who visited the restorative and prosthetic clinics in the period of 2016–2017 were included in the study.ResultsA total of 1186 patient records and OPGs were reviewed to extract the data. The average age of the patients in the study sample was 40.96 (±16.29). The sample included 751 (63.3%) female and 435 (36.7%) male patients. Among the patients, 192 (16.2%) had diabetes mellitus and 994 (83.8%) were non-diabetic. The average numbers of fixed partial dentures and missing teeth were significantly high among diabetic patients (P < 0.001). Conversely, the average numbers of carious lesions and restored teeth were higher among the non-diabetic patients. Only the number of restored teeth was found to be significant (P < 0.001).ConclusionThe diabetic patients were found to be at high risk of losing teeth compared with the non-diabetic patients. The prevalence of fixed partial dentures was also higher among diabetic patients. The oral health status of dental patients with diabetes needs urgent attention to prevent these patients from having teeth loss, and it can be done by improving their oral health. 相似文献
11.
The objectives of the study are to evaluate the relationship between common HIV-related oral lesions and absolute CD4+ count,
age, gender, and medication used and to assess the sensitivity, specificity, positive and negative predictive value of oral
manifestations for low absolute CD4+ counts. HIV-positive patients, 200, from south India were selected, whose absolute CD4+
counts were determined within 2 weeks of oral examination. Sociodemographic data was obtained using a structured questionnaire.
Oral manifestations were diagnosed according to presumptive criteria of EEC-clearinghouse classification (1993). Four or more
concurrent oral lesions were statistically significant with low CD4+ counts <200 cells/mm3 (P = 0.005). The highest and lowest mean CD4+ cell counts were seen in individuals with linear gingival erythema (LGE; 172.5
cells/mm3) and pseudomembranous candidiasis (PC; 87 cells/mm3), respectively. Smoking, age (<35 years), and males had a positive association with oral hairy leukoplakia (OHL; P < 0.05). Patients with CD4+ counts < 200 cells/mm3 were associated with 15 times greater risk of PC and four times at greater risk for occurrence of any oral manifestation.
Concurrent oral manifestations (≥4) were good predictors (80–100%) of severe immune suppression. In most resource poor countries
where facilities for undertaking CD4+ counts are not available, the presence of concurrent oral manifestations may be used
as an indicator of deteriorating immune status. 相似文献
12.
Neda Babaee Arash Mansourian Fatemeh Momen-Heravi Aliakbar Moghadamnia Jalil Momen-Beitollahi 《Clinical oral investigations》2010,14(1):65-70
Recurrent aphthous stomatitis (RAS) is a common, painful, and ulcerative disorder of the oral cavity with unknown etiology.
Treatment is a highly controversial topic. The aim of this study was to evaluate the clinical efficacy of a novel paste containing
Myrtus communis (Myrtle) in the treatment of recurrent aphthous stomatitis. Myrtle is a particular herb used in some cultures as treatment
for mouth ulcers. The study was a randomized, double-blind, controlled before–after clinical trial. Forty-five patients with
RAS randomly participated in this study. The subjects were treated with placebo paste and myrtle oral paste in two consecutive
episodes. The paste was applied by subjects themselves four times a day for 6 days. Five parameters (size change, pain scale,
erythema and exudation level, oral health impact profile, and patient overall assessment of their treatment) were recorded
both before (baseline) and during each episodes of treatment (on the morning of days 2, 4, and 6). There were no statistically
significant differences between baseline parameters (p > 0.05). The data indicated a statistically significant reduction of ulcer size (p < 0.001), pain severity (p < 0.05), and erythema and exudation level (p < 0.001). Oral Health Impact Profile improved significantly in the treatment group (p < 0.001). Patient overall assessment of their treatment improved after applying paste containing myrtle (p < 0.05). No side effects were reported. This study has shown myrtle to be effective in decreasing the size of ulcers, pain
severity and the level of erythema and exudation, and improving the quality of life in patients who suffer from RAS. 相似文献
13.
Obesity, dental caries and periodontal diseases are among major public health concerns which may affect children’s growth
and development. This study seeks any clustering between obesity, oral health and life-style factors among school children
in Istanbul, Turkey. A cross-sectional study of children, 10- to 12-year-olds, from a public and a private school was undertaken
with questionnaires for children and their mothers and child oral health data, in Istanbul (n = 611). DMFS (number of decayed, missing and filled surfaces of permanent teeth), CPI (Community Periodontal Index), body
mass index (BMI) and life-style factors (tooth-brushing frequency, milk consumption at breakfast and bedtimes on school nights)
of children were examined. Data analysis included factor analysis, Student’s t test and Chi-square tests by cross-tabulation. Public school children were more dentally diseased but less obese than were
those in private school (P < 0.001). They more frequently had calculus (62%) and reported non-recommended tooth-brushing (68%) than did those in private
school (37%, 56%; P < 0.05). Principal component analysis revealed that DMFS, CPI and BMI shared the same cluster among all children. A need exists
for addressing obesity, oral health and nutrition jointly in health promotion strategies to improve children’s well-being
and empower good life-style factors. 相似文献
14.
Håkan Flink Åke Tegelberg Judith E. Arnetz Dowen Birkhed 《Acta odontologica Scandinavica》2020,78(3):229-235
AbstractObjective: The aim was to study prevalence of xerostomia, hyposalivation and quality of life among caries active younger adults.Materials and methods: A questionnaire regarding oral and general health, xerostomia and quality of life was mailed to 134 caries active (CA) and 40 caries inactive (CI) patients, 25–50 years of age (mean age 39.9?±?6.2 years) treated at a Swedish Public Dental Service clinic, regarding oral and general health, xerostomia and quality of life. Caries data and unstimulated whole salivary flow rates were obtained from dental records.Results: The overall response rate was 69%. Dental records confirmed that CA patients had more decayed teeth over time than CI patients (p?<?.001). The CA group reported worse oral health (p?<?.001) and general health (p?<?.01), more xerostomia (p?<?.001) and lower salivary flow rate (p?<?.01) compared to CI patients. Xerostomia was inversely related to unstimulated whole salivary flow rates as well as to oral and general health (p?<?.01). There were no differences between groups in quality of life.Conclusion: Younger caries active adult patients reported significantly more xerostomia and hyposalivation compared to caries inactive patients. Xerostomia and hyposalivation were inversely related to perceptions of oral and general health, but not to quality of life. 相似文献
15.
Sakallioğlu EE Aliyev E Lütfioğlu M Yavuz U Açikgöz G 《Clinical oral investigations》2007,11(2):115-120
It has been demonstrated that diabetes mellitus (DM) may have an inductive effect on the vascular endothelial growth factor
(VEGF) levels of periodontium during periodontal disease. The aim of this study is to confirm this phenomenon, investigating
whether it is also valid for diabetic periodontitis patients under good metabolic control. Sixteen type II DM patients, all
with a glycosylated hemoglobin (HbA1c) value less than 7 (test), and 15 systemically healthy (control) chronic periodontitis
patients were included in the study. The VEGF concentrations in the gingival supernatants and gingival crevicular fluid (GCF)
samples of the study groups were measured by enzyme-linked immunosorbent assay. The data were analyzed by Student’s t test in statistical means. The VEGF levels were significantly higher in the gingival supernatants of the test group (55.89 ± 8.11 pg/ml)
than that of the control group (24.81 ± 2.04 pg/ml; p < 0.01). However, there was no statistically significant difference in the VEGF levels of GCF between the study groups (38.96 ± 4.89 pg/ml
in the test and 32.20 ± 4.02 pg/ml in the control group; p > 0.05). Our study confirms that DM affects the VEGF levels of periodontal soft tissues in periodontal disease, and our results
also suggest that this effect may not be influenced by the metabolic control of DM. 相似文献
16.
Ogunbodede EO Fatusi OA Akintomide A Kolawole K Ajayi A 《The journal of contemporary dental practice》2005,6(4):75-84
Oral manifestations of diabetes mellitus have been documented, but the effect of glycemic control on the oral tissues has been scantily reported. The oral health status of 65 metabolically controlled adult diabetic patients attending the Diabetes Clinic of Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria, was prospectively assessed over six months and compared with that of 54 non-diabetic acting as controls. The mean duration of diabetes was 100.5+/-85.1 months. The difference in periodontal status of the patients and control, assessed using the Community Periodontal Index of Treatment Needs (CPITN), was not statistically significant (p=0.07). The degree of hyposalivation between the two groups was, however, statiscally significant (p<0.05). No significant difference was observed in the altered taste, burning mouth sensation, angular cheilitis, glossitis, and stomatitis status of the two groups. We conclude, with adequate metabolic control, the oral health status of a diabetic may not be significantly different from that of a non-diabetic except for xerostomia. A good understanding of the interactions between systemic diseases and oral health is imperative for physicians and dental practitioners. The need for early detection and closer linkages between the dental and medical professions in managing diabetic patients is emphasized. 相似文献
17.
This study covers phase IV of a prospective clinical long-term study. Objective of this clinical investigation was to analyze
the effects of a long-term prevention program on dental and oral health of teenagers at the age of 13 to 14 years. The entire
study was subdivided into four phases. Phase I comprised an individual preventive care during pregnancy (“primary-primary
prevention”); phase II assessed mothers and their young children until the age of 3 years (“primary prevention”); and in phase
III, mothers and children at the age of 6 years were investigated. In phase IV of the study, the oral health of 13- to 14-year-old
teenagers was examined (13.4 ± 0.5 years; n = 29). All phases consisted of an examination, education about oral health care, and treatment based on the concept of an
early oral health care promotion. The control group consisted of randomly selected adolescents at the same age (n = 30). The following clinical parameters were assessed: decayed/missing/filled teeth (DMF-T)/decayed, missing, and filled
surface teeth index, hygiene index, papilla bleeding index, Periodontal Screening Index, and Streptococcus mutans/Lactobacillus
concentration in saliva. The teenagers of the “prevention” group of phase IV of our prospective study revealed a share of
89.7% caries-free dentitions (65.5% sound; 24.2% caries-free with fillings). Mean DMF-T was 0.55 ± 1.0. The control group
showed a significantly higher mean DMF-T of 1.5 ± 1.5 (p < 0.05) and revealed 56.7% of caries-free dentitions (30% sound, 26.7% caries-free with restorations). Our data clearly document
that an early oral health care promotion starting during pregnancy may cause a sustained and long-term improvement of the
oral health of children. 相似文献
18.
Christian J. Mehl Sönke Harder Matthias Kern Stefan Wolfart 《Clinical oral investigations》2011,15(2):193-199
The purpose of this study was to compare the patients' and dentists' perception of dental appearance. Based on internationally
accepted guidelines about dental esthetics, a questionnaire was developed to measure “dental appearance” (QDA). Eleven items
defined a QDA sum score (0 = “absolutely satisfied”, 44 = “absolutely dissatisfied”). The QDA was completed by 16 patients
(eight women, eight men, mean age 63 ± 9 years) before and after a complete oral rehabilitation. Forty-two dentists evaluated
the esthetics before and after rehabilitation on a visual analog scale (VAS, 0 = “absolutely unesthetic”, 100 = “absolutely
esthetic”). The patients' quoting showed a significant esthetic improvement (QDA sum score) from 22 before treatment to 3.5
after treatment (P ≤ 0.001). Although most of the dentists judged an improvement in most of the patients dental appearances, no significant
correlation could be found between patients' and dentists' judgment regarding dental appearance (r = −0.13–0.53, P > 0.05). When evaluating the influence of age, gender, and experience on rating dental appearance, no significant differences
(P > 0.05) could be found. 相似文献
19.
This study compared the depression status of adolescents with temporomandibular (TM) pain to those without, considering the
influence of age, sex, and other pain conditions. From a general population sample of 455 adolescents, 29 cases (mean age,
15.3 years) with current TM pain were compared with 44 age-matched controls without such pain. Study participants were examined
for general health status, additional pain sites (back, abdomen, and head) in the previous month, and depression, using a
15-item German-language depression questionnaire. Cases had a statistically significant higher average depression score than
controls (14.2 ± 7.1 vs. 9.7 ± 6.3; t test, p < 0.01), and they reported more often additional pain. The more pain sites were mentioned, the higher was the depression
score [no pain, 4.0 ± 2.8; four pains, 17.3 ± 8.0; analysis of variance (ANOVA), p < 0.001]. We conclude that TM pain assessment among adolescents should include a whole-body pain drawing as well as a screening
questionnaire to identify pain-related depressive symptoms. 相似文献
20.
Dental erosion is a common oral finding in chronic renal failure and may develop due to extrinsic and/or intrinsic causes.
The aim of this study was to compare the salivary calcium and phosphorus levels, salivary flow rate, salivary buffer capacity,
salivary pH, serum calcium and phosphorus levels and parathyroid hormone levels in chronic renal failure patients with and
without dental erosion. Twenty-four men and 19 women who had had chronic renal failure for at least 2 years were studied.
Twenty-two subjects displayed erosion-like patterns on their teeth and the other 21 patients showed no signs of erosion. Two
closely age- and sex-matched control groups (control groups 1 and 2) were enrolled in this study because of the age disparity
between the erosion and non-erosion groups. The data were analyzed by Mann–Whitney U test, Student t test, Pearson’s and Spearman’s correlation tests. None of the comparisons were statistically different between the erosion
and non-erosion groups. There were statistically significant differences in salivary calcium (P < 0.01) and phosphorus (P < 0.01) levels, serum phosphorus level (P < 0.01) and serum PTH level (P < 0.01) for the erosion group and control group 1 and also for the non-erosion group and control group 2. There was also
a significant difference in salivary flow rate (P < 0.05) for the erosion group and control group 1. There was a positive significant correlation between saliva buffer capacity
and salivary phosphorus level (r = 0.454, P < 0.05) in the erosion group. 相似文献