The use of the LARS artificial ligament to augment a short or undersized ACL hamstrings tendon graft

The aim of this study is to evaluate the midterm results of using Ligament Advanced Reinforcement System (LARS) artificial ligament for augmentation of the short (< 15 cm length) and small-sized (3–4 mm) diameter for the gracilis and (4–5 mm) for the semitendinosus harvested hamstring tendons in anterior cruciate ligament (ACL) reconstruction, and to assess the knee stability, patient satisfaction and early- and midterm complications following surgery. A total of 112 patients were included in this study and were operated with arthroscopic ACL reconstruction using (augmented hamstring tendon graft with LARS) between January 2004 and December 2006. Assessment before and after the surgery include the history, clinical examination, modified international knee documentation committee score (IKDC), KT1000 measurements for clinical knee stability and osteoarthritis outcome score (KOOS) for patient satisfaction. Clinical results measured by IKDC evaluation, KT1000 and Lysholm scores showed significant postoperative values compared with the preoperative ones. Our findings suggest that at the end of a 5-year follow-up, augmented hamstring tendon graft with LARS artificial ligament is a useful, safe and satisfactory treatment option for ACL reconstruction in deficient knees with short- and small-sized harvested hamstring tendons, especially when an early return to high levels of sport activity is needed.     

LARS人工韧带同时重建前、后交叉韧带

目的探讨关节镜下LARS（Ligament Advanced Reinforcement System，LARS）人工韧带同时重建前（An-terior cruciate ligament，ACL）、后交叉韧带（posterior cruciate ligament，PCL）的方法和临床疗效。方法从2006年1月至2007年4月，用LARS人工韧带同时重建ACL、PCL2例。应用Lysholm功能评分表评估膝关节功能，采用抽屉实验检查膝关节前后松弛度。结果2例均获得随访，随访时间分别为8月、3月。2例患者术后患膝关节不稳定症状消失，胫骨后坠征阴性，前、后抽屉试验阴性。膝关节功能评估采用Lysholm功能评分标准，术前平均分别为45．6±7．6分，术后平均为80．3±9．1分。结论关节镜下应用LARS人工韧带同时重建ACL、PCL可更好地恢复膝芙节的稳定性，且创伤小，并发症少，近期疗效满意，但远期效果仍需进一步观察。     

关节镜下LARS人工韧带与自体腘绳肌腱重建前交叉韧带临床疗效比较的meta分析

目的:系统评价关节镜下LARS人工韧带与自体腘绳肌腱重建前交叉韧带在疼痛的控制和膝关节功能恢复等方面的有效性和安全性.方法:采用计算机和手工检索PubMed,The Cochrane Library,EMBASE,中国知网(CNKI),维普数据库(VIP)和万方数据库,搜集关节镜下LARS人工韧带与自体腘绳肌腱重建前交叉韧带临床疗效比较的前瞻性临床对照研究文献,检索时限均为从建库至2016年8月.根据渥太华纽卡斯尔标准(Newcastle-Ottawa Scale,NOS)评估纳入的研究方法学质量,采用RevMan S.3软件进行meta分析.结果:共纳入8项前瞻性临床对照研究,371例前交叉韧带损伤患者.meta分析结果显示:LARS人工韧带移植组与自体肌腱移植组术后6个月Lysholm评分,MD=12.46,95％CI:12.46～15.74,差异有统计学意义(P＜0.001);术后6个月滕纳尔(Tegner)评分,MD=1.72,95％CI:1.45～1.99,P＜0.001,差异有统计学意义;术后12个月Lysholm评分,MD=4.31,95％CI:-0.70～9.32,差异无统计学意义(P=0.09);术后12个月Tegner评分,MD=0.52,95％CI:-0.21～1.24,差异无统计学意义(P=0.16).结论:在术后6个月时LARS人工韧带移植较自体腘绳肌腱移植进行前交叉韧带重建的效果更好;在术后12个月时,LARS人工韧带移植与自体腘绳肌腱移植进行前交叉韧带重建的疗效相当.     

LARS人工韧带Ⅰ期重建前后交叉韧带附2例报告

目的探讨LARS人工韧带同期重建前后交叉韧带的临床效果。方法两例前后交叉韧带同时断裂的男性患者,分别为38岁和58岁,均在关节镜下Ⅰ期接受LARS人工韧带重建膝关节前后交叉韧带。结果两例患者随访时间均超过4个月,术后6周和8周内恢复正常行走,前后抽屉试验,内外翻应力试验,屈伸活动范围在120°以上,没有明显并发症。术后Lysholm评分分别为87分和85分。结论LARS人工韧带是目前关节外科的一个很好的选择,尤其是在Ⅰ期重建前后交叉韧带时具有手术操作容易,创伤小,短期效果理想、不影响以后翻修等优点,缺点是费用昂贵,其长期效果还需要更多病例和更长时间的随诊来证实。     

Correlation between patients' satisfaction and objective measurement of knee stability after ACL reconstruction using a patellar tendon autograft

We evaluated the relationship between patients' satisfaction and objective measurements of knee stability after reconstruction of the ACL using a patellar tendon autograft. An examination of 59 patients 2-7 years after surgery was carried out. Assessment was made by the Knee and Osteoarthritis Outcome Score for patient satisfaction, a modified International Knee Documentation Committee form for clinical knee stability and a Telos stress radiography for PA stability. The results show that patients' satisfaction was much greater than the objective evaluation would suggest. We conclude that documenting mechanical knee stability alone is inadequate for follow-up studies and a questionnaire assessing patient satisfaction should be added.     

膝关节脱位致多韧带损伤Ⅰ期修复重建的疗效

目的:探讨膝关节脱位致膝关节前、后交叉韧带及内侧副韧带损伤后一期修复的疗效.方法:回顾性分析28例膝关节脱位致膝关节前、后交叉韧带损伤及合并内侧副韧带Ⅲ度损伤或完全断裂的患者行Ⅰ期修复重建的疗效.其中车祸事故伤22例,军事训练伤4例,高台坠落伤2例.损伤至手术时间6～17(平均7)d.膝关节Lysholm评分为21.7±6.52,国际膝关节文献委员会(International Knee Documentation Committee,IKDC)评分为17.42±11.56,关节活动范围为(27.2±19.6)°.合并内外侧半月板复合裂伤15例.通过关节镜下探查清理关节腔周围合并损伤后,采用患者自体半腱肌股薄肌肌腱重建前交叉韧带(anterior cruciate ligament,ACL),人工韧带(ligament advanced reinforcement system,LARS),韧带重建后交叉韧带(poster cruciate ligament,PCL),并使用带线锚钉修复内侧副韧带(medial cruciate ligament,MCL).结果:患者出院后均获随访,随访时间为6～24(平均18.2)个月.术后2年Lysholm膝关节功能评分为89.23±9.23,关节活动范围116.56°±12.8°,IKDC评分为88.74±8.74,与术前评分对比差异有统计学意义(P＜0.05).结论:在膝关节脱位致多韧带损伤的治疗方案中,Ⅰ期关节镜下行ACL和PCL重建术,并使用带线锚钉修补MCL断端,患者受到的损伤小,术后膝关节的稳定性恢复佳,通过进一步的康复理疗,关节粘连发生率较低,可得到相对满意的近期疗效,此方法值得临床参考并借鉴.     

10-16 year results of Leeds-Keio anterior cruciate ligament reconstruction

Following initial enthusiasm in the late 1980s, the use of artificial ligament substitutes for anterior cruciate ligament (ACL) reconstruction has declined. However, the disadvantages of donor site morbidity for autologous graft and concerns about cross-infection from allogenic material have resulted in a maintained interest in prosthetic ligament substitutes. This study presents the outcome of ACL substitution using the Leeds-Keio (LK) polyester ligament at a mean of 13.3 years (range 10-16 years). Outcome was assessed using the International Knee Documentation Committee score, the Lysholm knee score, Tegner activity scale and American Knee Society Score and laxity by clinical examination and the Stryker Knee Laxity Tester. Standardized radiographs were taken to assess for evidence of degenerative change. The objective scoring tests showed that all patients experienced some degree of symptoms from their knee but functional impairment varied widely. Of the group, 28% were known to have ruptured their LK ligament and 56% had increased laxity compared with their opposite knee but no correlation could be shown between rupture, increased laxity and poor function. Of particular concern, all post-operative knees had radiographic signs of degenerative change compared with a rate of 39% in the contralateral knees.     

创伤后膝骨关节炎发展中前交叉韧带损伤的作用与意义#br#

文题释义： 创伤后骨关节炎：又称外伤性骨关节炎、损伤性骨关节炎,它是由创伤引起的以关节软骨的退化变性和继发的关节周围骨质增生为主要病理变化,以关节疼痛、活动障碍为主要临床表现的一种疾病。任何年龄组均可发病,但以青壮年多见,多发于创伤后、承重失衡及活动负重过度的关节。 前交叉韧带损伤：一般出现在体育运动中,橄榄球、篮球、足球、滑雪等项目尤其多见。除了膝关节与他人碰撞致伤外,78%的前交叉韧带损伤为非接触性,常发生于落地、急停及暴力扭转等动作。足球运动中,移位防守以及奔跑中踢球相对危险;篮球运动中,侧跳转身以及单腿落地相对危险;在滑雪运动中滑雪板前端受阻时,膝关节外翻旋转,是较为典型的前交叉韧带非接触性损伤机制。 背景：前交叉韧带具有稳定膝关节、限制胫股关节在胫骨前平移和旋转的作用,大多数前交叉韧带重建患者膝关节疼痛和膝关节不稳的概率增加。创伤后膝骨关节炎是前交叉韧带损伤后的严重并发症,目前其机制尚不完全清楚。 目的：综述前交叉韧带损伤与创伤后膝骨关节炎发病因素之间的关系,从而为创伤后膝骨关节炎的治疗提供帮助。 方法：第一作者应用计算机检索PubMed数据库自建库以来至2019年10月的相关文章,英文检索词“ACL injury,traumatic knee osteoarthritis,ACL reconstruction,meniscus status,body mass index,cartilage injury,age,graft selection,time interval between injury and surgery”。共检索到123篇相关文献,66篇文献符合纳入标准。 结果与结论：①半月板状态、体质量指数、软骨损伤、年龄、移植物选择、受伤与手术之间的时间间隔这些因素会对创伤后膝骨关节炎的发展产生影响;②虽然前交叉韧带重建主要是恢复前交叉韧带断裂后的稳定性,该过程的一个长期目标是降低膝关节骨关节炎产生的风险,并维持关节长期处于健康状态;③患者前交叉韧带断裂后伴随半月板损伤需要进行半月板切除也是导致膝骨关节炎的原因,这很可能是由于关节的承受力减弱和关节运动学改变所致。 ORCID: 0000-0001-9413-439X(韩广弢) 中国组织工程研究杂志出版内容重点：人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程     

人工韧带生物材料修复膝关节交叉韧带损伤：问题及前景

BACKGROUND: Related studies have confirmed that the experimental results and short-term clinical outcomes of artificial ligaments are satisfactory that the artificial ligaments can restore the stability of knee joint as soon as possible and ensure motor function. OBJECTIVE: To summarize the basic and clinical research progress of artificial ligaments. METHODS: The articles regarding artificial ligaments in repair of knee joint cruciate ligament injury were retrieved from Wanfang database, CNKI and PubMed database during 1985 to 2015 by computer. The keywords were “cruciate ligament injuries, artificial ligament, biological materials” in Chinese and English, respectively. RESULTS AND CONCLUSION: Compared with autologous and allogenic ligaments, artificial ligament has good mechanical properties, and can get sufficient tensile strength and joint stability immediately after implantation, so as to ensure the cruciate ligament reconstruction of the knee joint. Artificial ligament technology has experienced carbon fiber ligament, polyester material and stent artificial ligaments. As a new type of polyester artificial ligament, LARS artificial ligament shows a good biocompatibility, on which, cells can adhere, proliferate and differentiate well. However, the controversies over the use of artificial ligament still exist, and its long-term clinical effects still need further observation. Further researches regarding the material selection, shape bionic design, weaving and surgical techniques of artificial ligaments are still further needed.      

自体腘绳肌腱与人工韧带加强系统重建前交叉韧带的比较

目的比较自体腘绳肌腱(HT)和人工韧带加强系统(LARS)重建前交叉韧带(ACL)的效果。方法选择61例ACL断裂患者(均为单侧断裂),其中男性37例,女性24例;年龄17~57岁,平均年龄36岁。采用自体HT重建ACL30例(HT组),采用LARS重建ACL31例(LARS组)。按Lysholm评分系统及KT-2000检查评估功能。结果全部病例均获随访,随访时间26~30个月。Lysholm评分术后2年HT组和LARS组分别为(90.80±8.87)分、(91.70±6.54)分;KT-2000测试膝关节移动距离分别为(2.58±2.18)mm、(2.39±2.09)mm。两组膝关节Lysholm评分在术后均较术前改善,差异有统计学意义(P0.05)。两组间术后Lysholm评分及膝关节稳定性KT-2000检查比较,差异无统计学意义(P0.05)。结论两种移植物均能够获得满意的临床效果,明显改善膝关节功能,LARS是一种良好的替代移植物。     

Satisfaction with playing pre-injury sports 1 year after anterior cruciate ligament reconstruction using a hamstring autograft

BackgroundFew studies have examined patient satisfaction with playing pre-injury sports after anterior cruciate ligament (ACL) reconstruction. The purpose of this study was to investigate patient satisfaction with playing pre-injury sport and identify factors associated with satisfaction.MethodsA total of 97 patients underwent unilateral ACL reconstruction using a hamstring autograft and returned to pre-injury sports 1 year after surgery. Patient satisfaction with playing pre-injury sport was assessed by a visual analog scale (VAS) and an ordinal four-grade scale. Problems related to the operated knee were also assessed. Knee muscle strength, single leg hop distance, knee laxity, subjective knee pain, and fear of movement/reinjury using Tampa Scale for Kinesiophobia-11 (TSK-11) were measured. Multivariate linear regression analysis was performed to determine the factors associated with patient satisfaction with playing pre-injury sport 1 year after surgery.ResultsThe average VAS score for patient satisfaction with playing pre-injury sports 1 year after surgery was 77.8 ± 20.2. Of the 97 patients, 87 patients (89.7%) answered “satisfied” or “mostly satisfied”, whereas 51 patients (52.6%) had one or more problems. Multivariate linear regression analysis identified that the TSK-11 score was associated with patient satisfaction with playing a pre-injury sport 1 year after surgery.ConclusionMost of the patients who returned to pre-injury sports were satisfied with their outcomes. In contrast, approximately half of the patients had one or more problems after returning to play pre-injury sports. In particular, fear of movement/reinjury was significantly associated with patient satisfaction with playing pre-injury sport 1 year after surgery.     

Selective bundle reconstruction in partial ACL tears leads to excellent long-term functional outcomes and a low percentage of failures

BackgroundThe optimal treatment of partial anterior cruciate ligament (ACL) tears continues to be debatable. Short-term results of selective bundle reconstruction have already been widely shown. The purpose of this study was to assess functional outcomes, subjective satisfaction and the failure rate of selective bundle reconstructions for partial ACL tears over a five to nine year follow-up period.MethodsPatients who underwent ACL selective bundle reconstruction between October 2008 and October 2012 were studied. Functional assessment was performed with the objective International Knee Documentation Committee (IKDC) ligament evaluation form, the Lysholm knee scale and the Tegner activity level scale. Cumulative failure and level of satisfaction have also been investigated.ResultsSeventy-six patients were included. The average follow-up period was 85 months (range 65–110). Thirty-four had AMB tear and 42 had PLB tears. An overall statistically significant improvement (p < 0.001) was obtained in terms of the subjective IKDC and the Lysholm questionnaire between preoperative and last follow-up. The same or no more than one level lower Tegner score was restored in 97.3% of the cases. Cumulative failure was observed in two patients (2.6%). Dissatisfied patient percentage was 15% (4/76).ConclusionsSelective bundle reconstruction in partial ACL tears leads to excellent long-term functional outcomes, a low percentage of failures and a high degree of subjective satisfaction in patients.Level of evidenceTherapeutic case series; level 4.     

Graft placement after the anterior cruciate ligament reconstruction: a new method to evaluate the femoral and tibial placements of the graft.

In order to evaluate graft placement of the anterior cruciate ligament (ACL) reconstruction and its relationship to the clinical outcome of the patient, 100 patients were examined 7 years after an ACL reconstruction. Clinical assessment was performed using the standard knee ligament evaluation form of the International Knee Documentation Committee (IKDC), and the Lysholm and the Marshall knee scores. We developed a new evaluation method of graft placement after an ACL reconstruction, 'the sum score of the graft placement', which takes into account both the femoral and the tibial positions of the graft simultaneously, and our study showed that 'the sum score of the graft placement' has an association to clinical outcome of patients and that it can better explain the long-term osteoarthritic changes at the injured knee than the separate measurements of the femoral and tibial tunnel placements.     

Anterior cruciate ligament reconstruction with autologous ipsilateral 1/2 peroneus longus tendon北大核心

BACKGROUND: Anterior cruciate ligament (ACL) injury is a commonly sport-induced knee joint injury that does serious harm to the knee stability. ACL reconstruction is a commonly used treatment method, but researches on 1/2 peroneus longus tendon (PLT) graft are rarely reported. OBJECTIVE: To investigate the clinical outcomes of removing the autologous ipsilateral 1/2 PLT under arthroscopy for ACL reconstruction. METHODS: 106 patients with complete ACL rupture in the Affiliated Hospital of Traditional Chinese Medicine, Southwest Medical University from December 2010 to December 2014 were enrolled, and autologous ipsilateral 1/2 PLT was removed under arthroscopy for ACL reconstruction. At baseline, 3, 6 and 12 months postoperatively, the knee stability was evaluated manually through the anterior drawer test, Lachman test, and pivot-shift test, and the knee function was evaluated by Tegner activity scale, Lysholm and International Knee Documentation Committee scores. RESULTS AND CONCLUSION: Postoperative anterior drawer test, Lachman test, and pivot-shift test tests were negative in all patients. In terms of Tegner activity scale, Lysholm and International Knee Documentation Committee scores, there were significant differences at baseline and postoperative 3 months as compared with postoperative 6 months (P < 0.05); the scores at baseline and postoperative 3 months showed significant differences compared with 12 months postoperatively (P < 0.05); the scores showed no significant difference between 6 and 12 months postoperatively (P > 0.05). These results indicate that autologous ipsilateral 1/2 PLT is a good choice for ACL reconstruction under arthroscopy, achieving rapid and satisfactory functional recovery of the knee joint, which is not only minimally invasive and easy to operate, but also exhibits good therapeutic efficacy. © 2017, Journal of Clinical Rehabilitative Tissue Engineering Research. All rights reserved.     

前交叉韧带重建后的满意度调查北大核心

BACKGROUND: There are many methods for evaluating anterior cruciate ligament reconstruction. However, doctors always like to assess the outcome with the objective criteria, such as range of motion and imaging examinations, and patient satisfaction is little considered. OBJECTIVE: To explore the factors that may influence the patient satisfaction after anterior cruciate ligament reconstruction. METHODS: Ninety-eight patients undergoing anterior cruciate ligament reconstruction were enrolled, including 58 male and 40 female patients, and the average age was 27.4 years old. All patients were followed up (average 17.5 months) to investigate the patient satisfaction. The factors related to the satisfaction were analyzed, such as age, follow-up time, sex, injured knee, mental health, education, economic situation, postoperative athletic ability, and International Knee Documentation Committee scores. RESULTS AND CONCLUSION: After the follow-up, 72.4% patients said that they were satisfied with the outcome, and 27.6% dissatisfied with the outcome. The mental health, economy situation, postoperative athletic ability, and International Knee Documentation Committee scores were significantly related to the patient satisfaction (P < 0.05). To conclude, improved living and medical standard, intensive communication and psychological counseling, as well as rational postoperative rehabilitation scheme can improve the patient satisfaction after anterior cruciate ligament reconstruction. [ABSTRACT FROM AUTHOR]     

非接触性前交叉韧带损伤特点及机制的研究进展

前交叉韧带断裂是膝关节最常见运动损伤之一,大部分是非接触性原因造成的。理解前交叉韧带受力和损伤机制对预防和治疗损伤有重要意义。本文综述了国内外对前交叉韧带损伤特点及其受力和损伤机制的研究结果。研究表明,下肢矢状面的生物力学是前交叉韧带受力的主要影响因素,如较小的膝关节屈角,较大的地面反作用力,较大的股四头肌力。其中较大的地面反作用力引发较大的股四头肌力和胫骨近端向前的拉力从而增加前交叉韧带负荷。较小的膝关节角合并较大的髌韧带与胫骨夹角和前交叉韧带倾斜角会增大韧带负荷。交叉韧带并不是承受膝关节内、外翻和内旋     

A systematic literature review to investigate if we identify those patients who can cope with anterior cruciate ligament deficiency

Rupture of the anterior cruciate ligament (ACL) results in increased tibiofemoral laxity in the knee, thereby ultimately resulting in knee instability and dysfunction. However, ACL rupture does not automatically infer functional impairment and instability as confirmed by the ACL deficient (ACLD) coper, who can resume pre-morbid activity levels. Alternatively, an authentic ACLD non-coper is unable to return to pre-injury levels of activity due to repeated incidents of giving-way. Little is known as to the contributory factors, which allows copers dynamic stability and render non-copers functionally impaired. This systematic literature review aims to examine the evidence presented by relevant trials in order to identify measurement tools, which could differentiate ACLD copers and non-copers. A literature search found nine trials; four adhered to the inclusion criteria of this review. Consensus was achieved within the studies that laxity measurements and IKDC ratings are incapable of distinguishing the functional status of the ACLD patient. Alternatively, Lysholm, KOS-Sport, KOS-ADL and Global Knee Function Rating Scores were regarded as capable of discriminating between ACLD copers and non-copers. Disagreement existed as to the efficacy of the Quadriceps Index and the single leg hop in categorising the ACLD patient according to function level. It was concluded that no single measurement tool is sufficient in determining the functional status of the ACLD individual. Consequently, a collaboration of tests is recommended, specifically incorporating the KOS-Sport, Global Knee Function Rating, hop tests and Quadriceps Index.     

关节镜下LARS韧带重建后交叉韧带的早期临床疗效分析

目的 回顾性分析关节镜下LARS韧带重建后交叉韧带的早期临床疗效。方法 自2016年8月~2017年10月筛选50例确诊为后交叉韧带损伤患者。其中应用LARS韧带重建后交叉韧带患者22例设为实验组,应用自体半腱肌、股薄肌重建后交叉韧带的患者28例设为对照组。记录患者术后并发症发生率,采用Lysholm、IKDC、Tegner膝关节运动评分标准对术后膝关节的稳定性与活动性随访评分。结果 所有患者均获得随访,随访时间3~6个月。对照组术后并发症的发生率高于实验组（21.43% vs 9.09%）,实验组在避免膝关节僵硬及下肢深静脉血栓方面优于对照组（4.55% vs 17.86%）,差异具有统计学意义（P＜0.05）;两组患者术前Lysholm评分、IKDC评分以及Tegner评分比较,差异无统计学意义（P＞0.05）,在术后随访过程中,实验组Lysholm评分、IKDC评分以及Tegner评分优于对照组,差异有统计学意义（P＜0.05）。结论 关节镜下LARS韧带重建后交叉韧带创伤小,降低术后并发症,有效的恢复膝关节的稳定性和功能性,具有较好的近期临床疗效。     

Outcome measurement in the ACL deficient knee--what's the score?

There is increasing pressure within the United Kingdom for transparent assessment of the performance of every doctor along with the procedures they perform. Unfortunately, the validation of the outcome measures used to assess such procedures has been questioned. This has been well illustrated in the anterior cruciate ligament (ACL) deficient knee. Over 54 different outcome measures used to assess the ACL deficient knee have been identified, few of which were formally assessed at their initial publication. For those most frequently used the Lysholm (I and II) knee scoring scale and Tegner activity score are the only ones to have been adequately validated prior to use. The Cincinnati rating system and International Knee Documentation Committee (IKDC) form were not assessed and the reliability of both measures has since been questioned. Appropriately tested newer measures include the IKDC subjective knee evaluation form, Mohtadi's ACL quality of life outcome measure and the Knee injury and osteoarthritis outcome score (KOOS). We recommend use of the Lysholm II knee scoring scale and Tegner activity score for clinical follow-up of patients and for use as a gold standard to which future measures can be compared. These have their deficiencies and will ultimately require replacement. In view of the international standing of its authors, the IKDC subjective knee evaluation form is likely to be used in preference to the KOOS despite its attractions. For long-term clinical trials the SF-36 should also be used. Further research is required to produce suitable measures for assessing the ACL deficient knee and this work should be appropriately funded.     

Medial/central PF arthritis and functionally stable ACL deficiency do not compromise outcomes of fixed-bearing medial UKA

BackgroundThere is limited published data assessing functional scores and patient satisfaction following unicompartmental knee arthroplasty (UKA) in patients with patellofemoral (PF) arthritis or anterior cruciate ligament (ACL) deficiency. The purpose of this study was to determine whether medial/central PF arthritis or functionally stable ACL deficiency compromise outcomes of fixed-bearing medial UKA at a minimum follow-up of 2 years. The hypothesis was that equivalent outcomes can be achieved in patients with substantial medial/central PF arthritis or with functionally stable ACL deficiency.MethodsThe authors studied a consecutive series of 229 patients (240 knees) at 36.9 ± 6.3 months after receiving fixed-bearing medial UKA. Patients completed pre- and post-operative (2 years) clinical outcome questionnaires for Oxford Knee Score (OKS), EQ-5D, Knee injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS), University of California, Los Angeles (UCLA) activity score, and Forgotten Joint Score (FJS). Multivariable analyses were performed to determine associations between clinical scores, patient demographics, PF arthritis and functionally stable ACL deficiency.ResultsOf the 240 knees, 125 (54%) had substantial medial/central PF arthritis and 21 (9%) functionally stable ACL deficiency. Multivariable analyses revealed no association between outcomes and medial/central PF arthritis, but knees with functionally stable ACL deficiency were associated with better KOOS-PS (β = 8.99, p = 0.012).ConclusionFixed-bearing medial UKA grants satisfactory outcomes at 2 years even in knees with substantial medial/central PF arthritis or functionally stable ACL deficiency. Longer-term prospective studies with larger cohorts are needed to confirm these promising findings regarding outcomes in patients traditionally contraindicated for medial UKA.