坚持方向,直面未来

<临床神经病学杂志>是国内著名的神经病学专业性学术刊物.刊登内容以临床神经病学为主,兼及相关边缘学科.20年来,由于几代人的努力,<临床神经病学杂志>已被评为中文医学类核心期刊、中国科技论文统计源核心期刊、美国化学文摘等多国收录期刊.     

当勤精进,再创更高、更快、更强

首先庆贺<临床神经病学杂志>在2008这一举国欢腾的吉祥年迎来创刊20周年纪念.高尔基先生曾说过,书籍是"不可分离的生活伴侣".执子之手,我们与<临床神经病学杂志>已经共同走过了20个春秋.在这20年的风雨历程中,我们不仅见证了她初嫁时的羞涩,更有历经岁月后的妩媚与成熟.     

开拓进取,与时俱进

<临床神经病学杂志>于1988年7月创刊,至今不经意间已走过了20年的征程.回顾20年前的<临床神经病学杂志>如一棵幼小的树苗,在主办单位领导的关怀和支持下,以及历届编委和广大作者、读者、专家的扶持和帮助下,茁壮成长,现已根深叶茂,高大挺拔,在全国神经科学专业杂志中已名列前茅.     

祝贺《中国临床神经科学》杂志创刊廿周年

<中国临床神经科学>杂志是广大从事临床神经病学研究的医务工作者及从事神经病学基础研究科技工作者的学术园地.2012年,我们十分高兴地迎来了<中国临床神经科学>杂志廿周年华诞,过去的20年间,在蒋雨平教授及编辑部团队的辛勤耕耘下,在全国老中青三代神经病学专家们的协力下,杂志不断壮大、不断出新、不断发展,在神经科学基础研究和临床研究之间建起了一座相互融合的平台,在广大读者、作者、编者之间架起了一座互相沟通的桥梁.20年来,<中国临床神经科学>杂志从内部发行发展为国内外公开发行;从季刊发展为双月刊;从64页增至80页乃至如今的120页.为我国神经科学基础和临床的发展史上书写了浓墨重彩的一笔.而今,杂志已步伐稳健地迈进第20年,它不仅是上海市、华东六省乃至全国的神经内、外科青年医生临床工作中的良师益友,也是神经内、外科同仁临床和科研工作中的重要参考资料之一.并先后列入了中国科技论文统计源期刊,中国学术期刊光盘录入期刊以及中国学术期刊综合评价数据库来源期刊等.可以预见,在未来的征程中,编辑部全体同仁与全体编委们必将会给广大读者呈现更加丰富的精神饕餮大餐.     

回顾与期盼

我想最喜欢阅读<临床神经病学杂志>(以下简称杂志)的人,大多数都是工作在各类型医院第一线的神经内科医师,尤其是基层医院的医师.因为这本杂志的内容能帮助他们增加信息量,更新知识和解决许多临床工作中遇到的难题.杂志中介绍的一些临床、基础研究和神经科学方面的内容,会有利于医师们从发病机制角度开阔思路,从而制定出切合病情的诊治方案.这本杂志亲切之处在于"临床"二字,这对临床医师确有着非常强的吸引力.     

致读者的信

<中国神经免疫学和神经病学杂志>自1994年创刊以来得到广大读者和作者的关心和支持,使本刊越办越好,为此向大家表示衷心感谢.     

沉痛悼念著名的神经病学家王新德教授

王新德教授是我国著名的神经病学专家、老年医学专家、第八届全国政协委员、原中华医学会神经病学分会主任委员、老年医学分会主任委员、中华医学会神经病学分会主编、<中风与神经疾病杂志>顾问、卫生部北京医院神经科主任,因病抢救无效于2009年10月31日7时28分在北京逝世,享年85岁.     

敬告读者

<正>《中风与神经疾病杂志》是中华人民共和国教育部主管、吉林大学主办的专业性核心学术期刊。于1984年3月创刊,主编为吴江教授,名誉主编为著名神经病学专家饶明俐教授和张淑琴教授,编委均为全国神经科知名教授学者。本刊的办刊宗旨是活跃学术交流,传播神经病学领域中代表我国学术水平的临床与基础研究等方面的新理论、新技术、新经验和新成果,介绍国际上的新进展,促进国内外学术交流,以推动我国神经病学的发展     

敬告读者

<正>《中风与神经疾病杂志》是中华人民共和国教育部主管、吉林大学主办的专业性核心学术期刊。于1984年3月创刊,主编为吴江教授,名誉主编为著名神经病学专家饶明俐教授和张淑琴教授,编委均为全国神经科知名教授学者。本刊的办刊宗旨是活跃学术交流,传播神经病学领域中代表我国学术水平的临床与基础研究等方面的新理论、新技术、新经验和新成果,介绍国际上的新进展,促进国内外学术交流,以推动我国神经病学的发展     

敬告读者

<正>《中风与神经疾病杂志》是中华人民共和国教育部主管、吉林大学主办的专业性核心学术期刊。于1984年3月创刊,主编为吴江教授,名誉主编为著名神经病学专家饶明俐教授和张淑琴教授,编委均为全国神经科知名教授学者。本刊的办刊宗旨是活跃学术交流,传播神经病学领域中代表我国学术水平的临床与基础研究等方面的新理论、新技术、新经验和新成果,介绍国际上的新进展,促进国内外学术交流,以推动我国神经病学的发展     

Handling clinical comorbidity in randomized clinical trials in psychiatry

The purpose of this paper is to a) outline the importance of including patients with clinical comorbidities in Randomized Clinical Trials (RCTs) of psychiatric treatments; and b) to propose a specific approach for best handling, analyzing and interpreting the data on clinical comorbidities in terms of their impact on treatment outcomes. To do this we first define and describe clinical comorbidity and differentiate it from other forms of comorbidity. We then describe the methodological and analytical problems associated with excluding patients with clinically comorbid conditions from RCTs, including the impact on the outcomes of RCTs in psychiatry and the impact on evidence-based clinical decision-making. We then address the challenges inherent to including patients with clinical comorbidities in RCTs. Finally, we propose a methodological and analytic approach to deal with these issues in RCTs which aims to significantly improve the information yielded from RCTs in psychiatry, and thus improve clinical decision-making.     

An opportunity to bridge the gap between clinical research and clinical practice: implications for clinical training

Clinical researchers and clinical practitioners share a goal of increasing the integration of research and clinical practice, which is reflected in an evidence-based practice (EBP) approach to psychology. The EBP framework involves the integration of research findings with clinical expertise and client characteristics, values, and preferences, and consequently provides an important foundation for conducting clinically relevant research, as well as empirically based and clinically sensitive practice. Given the critical role that early training can play in the integration of science and practice and in promoting the future of the field, the present article addresses predoctoral training programs as a context for adopting an EBP approach to clinical work. We address training in the three components of EBP and provide suggestions for curriculum development and practicum training that we hope will contribute to bridging the gap between research and practice.     

Intracranial lipomas: clinical appearances on neuroimaging and clinical significance

Intracranial lipomas are rare congenital malformations which are neither hematomas nor true neoplasms. They result from the abnormal persistence and maldifferentiation of the meninx primitiva. The majority of such lesions occur near the midline. Around 55% of intracranial lipomas are associated with brain malformations of varying severity. Although they are usually an incidental finding, symptomatic intracranial lipomas are sometimes observed. Surgical excision may result in high morbidity and mortality due to the highly vascular nature of intracranial lipomas and the latter’s strong adhesion to the surrounding tissue and is very rarely indicated.     

Epidemiological knowledge and clinical truth: objectivity and clinical practice

The authors analyse the difficulties of the knowledge given by epidemiological studies from the clinician's point of view. They propose three arguments to define the aid epidemiology can bring to clinicians: to give rise to hypotheses from clinical experience, validate some epidemiological results, and reflect on the integration of predictive knowledge in clinical practice. These arguments are illustrated by examples taken from the authors work and propositions of epidemiological studies of which the aim and the problematic could emanate from observation and clinical experiences.     

A clinical review

The optimal management of muscular dystrophy is multidisciplinary and aggressive in nature. Serial assessment aids in determining the functional stage of the disease and in indicating specific therapies. Physical therapy can augment strength through exercise and relieve contracture through passive stretching. Occupational therapy is employed to help the patient manage his activities of daily living within the restrictions imposed on him by his disease. Progressive disability can be delayed through a variety of physiatric and orthopedic techniques, including surgical release of lower-extremity contracture, repair of foot and ankle deformity, and correction of scoliosis. Appropriate orthoses are available, as are a variety of special devices to facilitate ongoing care for postambulatory patients. Physicians treating the muscular dystrophies should be aware of the complications of these diseases, particularly cardiomyopathy, pulmonary failure, and psychological and social problems.