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1.
Antonio Cano Sánchez Xavier Cortés Gil Ester Ramírez Vázquez 《Progresos de Obstetricia y Ginecología》2009
Objective
To determine the 5-year non-vertebral fracture risk in postmenopausal women on antiresorptive therapy.Subjects and methods
We performed a cross-sectional multicenter study in 2,111 postmenopausal women receiving antiresorptive therapy in gynecological settings. The risk of fracture was evaluated by means of the FRACTURE Index. The influence of clinical parameters on the main variable was evaluated through linear and/or logistic regression, using the SAS v. 9.1.3 program.Results
The mean age ± standard deviation was 61.0 ± 7.9 years. Densitometry was available in 60.5% of the women and showed a prevalence of osteopenia of 49.4% whereas that of osteoporosis was 42.4%. Biphosphonates were used in 59.3% of the women. When densitometry was available, 73.4% scored less than 6 points on the FRACTURE Index, and when densitometry was not available, 81.7% scored less than 4 points. The mean risk of non-vertebral fractures was 14.8 ± 5.3% and that of vertebral fractures was 4.0 ± 3.0%.Conclusions
In this large group of postmenopausal women receiving antiresorptive treatment, the 5-year non-vertebral fracture risk, as assessed by the FRACTURE index, was three times higher than that of vertebral fracture. 相似文献2.
Rafael Sánchez-Borrego Santiago Palacios José Luis Neyro Francisco Quereda Francisco Vázquez Maite Pérez 《Progresos de Obstetricia y Ginecología》2009
Objective
This study describes the profile and attitudes, knowledge and expectations of patients with postmenopausal osteoporosis.Subjects and methods
Epidemiological and cross-sectional study carried out in Spain. Participating patients were aged over 45 years and receiving treatment for postmenopausal osteoporosis. Data on personal and family medical history, diseases and concomitant medications, smoking and drinking habits, diet and physical activity, treatment and compliance were recorded. All patients completed a 17 item questionnaire on attitudes, knowledge and expectations related to their condition.Results
A total of 1179 valid patients with postmenopausal osteoporosis were included, with a mean age of 59.89 ± 7.53 years. Only 22.6% of the patients showed acceptable knowledge of osteoporosis. A large majority (74.6%) of the patients were very/quite concerned about their condition, and 53.3% described their health status as excellent/good. However, 63.6% of the patients indicated that they need more information about osteoporosis.Conclusions
The results of this study prove the need to provide accurate knowledge of their disease to patients with postmenopausal osteoporosis. 相似文献3.
J. Lorente J.A. MonserratJ.A. Borrego M. SantaellaJ. Cordón 《Progresos de Obstetricia y Ginecología》2006
Objectives
To determine the rates of cervical and vaginal disease in groups of asymptomatic women with risk factors and their degree of adhesion to the screening program.Patients and methods
269 asimptomatic women attended during 1 year (1998) were interrogated in relation to risk practices; they underwent pap smear, colposcopy-biopsy of the cervix and determination of antibodies for VIH. A follow-up was made during 5 years.Results
The prevalence of intaepithelial lesions was 26.8% and the accumulated incidence was 10.4%; 62.5% of the women never returned to revision more, whereas 37.6% returned at least once.Conclusions
The women of the studied groups show high rates of cervical-vaginal pathology and high risk of developing cervical cancer. The adhesion of these women to the screening program is very low. Because of the low precision of the citology, this women must undergo a second screening test. 相似文献4.
Aim
To evaluate the benefits of allowing oral intake of clear liquids in terms of labor duration, the cesarean section rate, and personal satisfaction.Methods
A randomized controlled trial was carried out to assess the effects of a clear liquid diet in a low risk population. The primary outcome was labor duration. The secondary outcome was the incidence of cesarean section. A satisfaction survey was performed within the first 2 h after delivery to evaluate the patient's perception of labor.Results
A total of 348 patients were randomized. The mean duration of labor was 257.75 min in the liquid diet group and 288.40 min in the fasting group (p = NS). There was no statistically significant difference (per-protocol analysis and intention-to-treat analysis) in the cesarean section rate.Patients reported greater satisfaction when allowed to drink during labor than when fasting.Conclusion
A clear liquid diet during labor did not alter the duration of labor or the cesarean section rate. Allowing a liquid diet during labor was associated with a better perception of the birth process and a higher degree of satisfaction. 相似文献5.
José L. Gallo Vallejo M. Teresa Aguilar Romero Esperanza González Perán Bárbara Romero Guadix Ángel A. Santalla Hernández 《Progresos de Obstetricia y Ginecología》2010
Objective
To review the characteristics of breast cancer in young women.Material and methods
The scientific literature was reviewed, indicating the etiological factors, diagnostic methods and treatment options, with special reference to the factors that can concur in young patients such as premature menopause, loss of fertility, pregnancy after breast cancer and breast cancer during pregnancy.Results
Importantly, breast cancer in young women is very rare but is on the increase. Tumors are larger in young women and have positive margins, making the disease more aggressive and leading to higher mortality. Diagnosis is more difficult than in older women and the triple test (mammography, ultrasound and biopsy) is of great importance. Treatment options are the same as in older women.Conclusions
Breast cancer in young women shows certain characteristics that differentiate it in some respects from breast cancer diagnosed in older women. 相似文献6.
Jorge Fernández Parra Aída González ParedesAntonio J. Rodríguez Oliver Francisco Montoya Ventoso 《Progresos de Obstetricia y Ginecología》2008
Objective
To determine the incidence of endometrial cancer in asymptomatic postmenopausal women with a sonographic endometrial thickness above 5 mm.Materials and methods
We performed a retrospective study of 270 asymptomatic postmenopausal women with endometrial thickness > 5 mm on sonography. All women underwent hysteroscopy with histological evaluation if required. The incidence of endometrial cancer was evaluated.Results
Five cases of endometrial cancer were diagnosed in the 270 women, representing an incidence of 1.85%. Of the 106 patients with a sonographic image leading to suspicion of polyp, four were diagnosed with endometrial cancer (3.77%), all of which were stage I tumors. None of the 270 women was receiving hormone replacement therapy.Conclusions
The incidence of endometrial cancer in asymptomatic postmenopausal women with sonographic suspicion of polyp was 3.77%. Patients with this sonographic finding should undergo thorough hysteroscopy and biopsy to rule out malignancy. We believe that the cut-off value for endometrial thickness in postmenopausal women without vaginal bleeding should be determined. 相似文献7.
Laura Yago Lisbona M. Rosario Noguero MeseguerBlanca Sancho Pérez Consuelo Sanz FerrándezMarta Gallego Álvarez José Manuel Hernández García 《Progresos de Obstetricia y Ginecología》2010
Background and objective
Two per cent of breast cancers develop in women aged 35 years old or younger. The aim of this study was to analyze the influence of the histological characteristics of the tumor and axillary involvement on the prognosis of the disease.Methods
We performed a retrospective study of 71 women aged 35 years old or younger diagnosed with breast cancer in the 12 de Octubre Hospital from 1983 to 2000. A survival curve was designed using the Kaplan-Meier method.Results
The most important prognostic factor was tumoral extension at diagnosis. A total of 66.7% of the patients in initial stage IV died within 5 years of follow-up. For stages 0 and I, 92.3% and 100% of the patients, respectively, were alive and had no evidence of disease. The most frequent histological type was infiltrating ductal carcinoma. Outcome was not influenced by tumoral type or histological grade. Recurrence was more frequent in patients with positive receptors than in those with negative receptors. One of the most important prognostic factors was axillary involvement. Recurrence occurred in 71.4% of the patients with nodal involvement compared with 31.4% of those without nodal invasion. The greater the number of affected nodes, the higher the risk of recurrence. Alteration of P53 and c-erb 2 were poor prognostic factors.Conclusions
Tumoral size and stage, axillary involvement and the number of affected nodes were associated with a higher risk of recurrence and worse 5-year outcome. The presence of positive receptors was also related to an unfavorable outcome. Fifty percent of women lived for more than 15 years. 相似文献8.
M.P. Hormaza Angel J.S. Lopera Valle M.M. Massaro Ceballos G.J. Rendón Pereira N. Campo Campo 《Clínica e investigación en ginecología y obstetricia》2014
Objective
To compare the prevalence of metabolic syndrome in postmenopausal women by applying the IDF and the NCEP/ATPIII criteria and to assess the risk of cardiovascular disease in postmenopausal women and associated risk factors.Material and methods
A cross-sectional study of 224 women aged ≥45 years was carried out following IDF and NCEP/ATPIII guidelines. Cardiovascular risk was estimated using Framingham projections of 10-year absolute cardiovascular disease risk and AHA cardiovascular disease risk assessment.Results
Among evaluated women, the mean age was 59 years (SD 8.36 years). Half of the women had had their last menstrual period >10 years previously, from the FUM (RIQ: 5-18). A total of 62.9% were overweight or obese. The prevalence of metabolic syndrome was 57.1% according to the IDF criteria (IC 95%: 50.4-63.7) vs. 37.5% according to the NCEP/ATPIII criteria (IC 95%: 31.1-44.2). Framingham score was >10% in 46% of the women. According to AHA criteria, 76.8% were at risk, or at high risk, for cardiovascular disease. In the multivariate analysis, the factors most strongly associated with metabolic syndrome according to IDF criteria were obesity (OR 5.05; IC 95%: 2.18-11.69) and age >65 years (OR 2.75; IC 95% 1.34-5.64). The factors most strongly associated with cardiovascular risk were hypertension (OR 11.58; IC 95%: 4.81-27.86), low levels of high-density lipoprotein cholesterol (OR 16.63; IC 95%: 5.96-46.37), and age >55 years (OR 4.5; IC 95%: 1.90-10.67).Conclusion
The joint application of the IDF criteria for metabolic syndrome and the AHA criteria for cardiovascular disease risk assessment is useful to identify a greater number of women at risk. 相似文献9.
Josep Lluis Carbonell i Esteve Orlando Perera Boza Ana María Riverón Cobo Jesús González Giuseppe Tomasi 《Progresos de Obstetricia y Ginecología》2012
Objectives
To evaluate the safety and efficacy of 5 mg and 25 mg doses of mifepristone for the treatment of endometriosis.Design
Randomized double-blind study.Setting
Eusebio Hernández Hospital, Havana, Cuba.Subjects
Twenty-six women laparoscopically diagnosed with endometriosis were included.Treatment
Group I received one tablet of 25 mg mifepristone daily and group II received one tablet of 5 mg mifepristone daily for 6 months. Laparoscopy and endometrial biopsy were performed before and after treatment.Variable to evaluate efficacy
Reduction in the intensity of dysmenorrhea measured by a visual analogue scale.Results
In both groups reductions in the intensity of dysmenorrhea and dyspareunia were highly significant compared with initial values (P <.001). All the women were amenorrheic after 45 days of treatment.Conclusions
At doses of 5 mg or 25 mg, mifepristone could be an alternative for the treatment of endometriosis. 相似文献10.
Objective
to evaluate how much education midwives in Sweden have undertaken to help them assess alcohol intake during pregnancy, and what tools they use to identify women who may be at risk of drinking during pregnancy.Design
a national survey was conducted in March 2006, using a questionnaire constructed by a Swedish team of researchers and clinicians.Setting
maternity health-care centres in Sweden.Participant
2106 midwives.Findings
nearly all midwives stated that they had excellent or good knowledge concerning the risks associated with drinking during pregnancy. They considered themselves less knowledgeable about detecting pregnant women with risky alcohol consumption before pregnancy. The majority of the midwives had participated in some education in handling risky drinking. Almost half of the midwives assessed women's alcohol intake before pregnancy. Important facilitators for increased activity concerned recommendations and decisions at different levels (national, local and management) on how to address alcohol with expectant parents and work with risky drinkers.Key conclusions
more education was associated with more common use of a questionnaire for assessment of women's alcohol intake before pregnancy, and more frequent counselling when identifying a pregnant woman whose pre-pregnancy consumption was risky. 相似文献11.
M. Dolores Juliá Javier Ferrer Francisco Quereda Concepción Navarro Carmen Menéndez Nicolás Mendoza Andrés Forteza Camil Castelo-Branco M. Jesús Cornellana M. Jesús Cancelo Estanislao Beltrán Luis Ignacio Bachiller Josep Allué José Villero Rafael Sánchez-Borrego Santiago Palacios Javier Haya Magdalena Durán 《Progresos de Obstetricia y Ginecología》2009
Objective
Due to an increasing interest in the symptoms related to menopause in western countries, the Spanish Menopause Society (SMS) has assessed the role of cimicifuga racemosa in relieving those symptoms based on the most reliable evidence available.Material and methods
A meeting was held with a panel of experts, health scientists and researchers specialised in the field of phytotherapy. The studies selected were obtained through electronic search which included INTERNET, MEDLINE (1985-May 2008), and the Cochrane Controlled Clinical Trials Register.Results
Most studies published in recent years have been carried out using an isopropanol extract of cimicifuga racemosa. The dose most commonly studied was 40mg/day and was shown to result in a moderate decrease in hot flushes, particularly in those women with the most intense hot flushes, and an improvement in their mood. When recommended doses are used there is no significant risk to the hepatic system. Available data on the effect of cimicifuga racemosa on cardiovascular disease, bones, cognitive function or skin are scarce or non-existent.Conclusions
Cimicifuga racemosa is an effective treatment for relief of vasomotor symptoms, at least within a suitable population of peri- and postmenopausal women. Nevertheless, more accurate clinical trials which include sufficient numbers of patients and a longer follow-up are required. 相似文献12.
Pedro José Cabeza Vengoechea Andrés Calvo Pérez Ana Pilar Betrán María del Mar Mas Morey María Mercedes Febles Borges Paula Ximena Alcácer Ana Ramallo Alcover Enrique Francisco Campos Villamiel Eva María Morán Antolín Sabine Rehkugler Francisco Javier Agüera Ortiz Olga Román Delgado Ana Román De la Peña 《Progresos de Obstetricia y Ginecología》2010
Objective
To identify groups of women with changes in cesarean rates in two different periods.Subjects and methods
Deliveries in the Manacor Hospital in 2000-2001 and 2005-2006, were analyzed through a retrospective review of clinical records and were grouped using Robsońs classification.Results
The cesarean rate increased from 14 to 18.6% with a statistically significant increase among women with a single cephalic pregnancy at term who underwent labor induction or elective cesarean section. These two groups were the major contributors to the cesarean rate at our hospital.Conclusion
A trend towards an increase in the rates of cesarean section was found during the study period. Robson's Classification allowed us to identify the groups of women contributing to this increase. 相似文献13.
Javier Agüera Ortiz M. del Mar Mas MoreyAndrés Calvo Pérez 《Progresos de Obstetricia y Ginecología》2008
Objective
To alert clinicians to the possibility of synchronous tumors in patients with gynecological cancer. An important tool in diagnosis is the family history. We describe several familial syndromes involving the development of synchronous gynecological tumors.Subjects and methods
We studied all cases of synchronous gynecological tumors in the Manacor Hospital from 1997 to 2006.Results
Synchronous gynecologic tumors represented 0.83% of all gynecological neoplasms treated in our center in the period studied.Conclusions
This kind of tumor is uncommon but should be considered by clinicians, especially in women with a familial history of cancer or in those with certain genetic syndromes. Examination aimed at excluding the presence of synchronous tumors is recommended. 相似文献14.
Nieves Gaitán José Luis Dueñas Carlos Bedoya Claudio Taboada Juan Polo 《Progresos de Obstetricia y Ginecología》2009
Introduction
There are very few studies published in the scientific literature to assess the real value of the x-ray pelvimetry (X-PM). The current recommendations on its use are based on a single meta-analysis that includes only four studies with a very low level of scientific evidence.Objectives
To evaluate the usefulness of the X-PM in induction in primiparous women for the diagnosis of pelvic-cephalic disproportion and analysing its influence on the duration of pregnancy, neonatal mortality and the rate of caesarean sections.Materials and methods
The observational, prospective, randomised, double-blind, study, in a population of 264 primigravid pregnant women in whom induction of labour was an indication.Results
X-ray pelvimetry did not influence the rate of caesarean section or the perinatal results, and has a low predictive value as a prognostic factor in the method of delivery. 相似文献15.
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17.
Carlos Gegúndez Gómez Inmaculada Monjero AresM. Victoria Martín Vidal Josefina Cao PenaJosé Conde Vales Isabel Pérez MoreirasJosé Félix Arija Val 《Progresos de Obstetricia y Ginecología》2009
Objective
To evaluate which factors are related to the presence of residual tumor after lumpectomy for breast cancer with a view to determining the excisional biopsy margins that guarantee a complete excision.Material and methods
The records of 118 women with invasive breast carcinoma who were treated with lumpectomy in our service between June 2004 and December 2006 were retrospectively reviewed. The parameters evaluated were age, palpability, diagnostic method, type of initial and definitive surgery, histologic type, tumor size, lymphovascular invasion, presence/absence of extensive intraductal component (EIC), estrogen receptors, surgical margins, reexcision, and the presence of residual tumor.Results
Residual disease was found in 27%. In the univariate analysis, only margins (P=.015), EIC (P=.026) and size (P=.025) were significantly associated with the presence of residual tumor. With simple lineal regression analysis, only margins (P=.008) and EIC (P=.025) showed a significant association.Conclusions
We believe that a minimum margin of 2 mm is enough to guarantee the absence of residual breast cancer if there is no EIC. In patients with margins ≤ 2 mm, the presence of EIC is an indication of high risk of residual disease. 相似文献18.
Sara Roldán Baños Jesús Márquez Rojas Belén Andújar Quirós Amador García Blanco Gerardo Blanco Fernández Francisco Galeano Díaz 《Progresos de Obstetricia y Ginecología》2012
Background
Although intrauterine device is safe for the most women, its association with liver abscess has been reported and can produce fatal sepsis.Clinical case
We report a case of a patient wearing intrauterine device who arrived at the emergency department with acute abdomen due to ruptured liver abscess. The patient underwent exploratory laparotomy for surgical drainage.Conclusion
Intrauterine device can be considered the etiology in a woman with intraabdominal infection. 相似文献19.
20.
Ruth Carpintero Franco Rosario Noguero MeseguerBlanca Sancho Pérez Marta Gallego ÁlvarezConsuelo Sanz Fernández Ignacio Herraiz GarcíaJ.M. Hernández García 《Progresos de Obstetricia y Ginecología》2007