共查询到20条相似文献,搜索用时 46 毫秒
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《临床合理用药杂志》2009,(6):33-33
美国食品和药物管理局近日宣布,由于可能引发一种罕见的致命脑部疾病,美国遗传技术研究公司即日起自愿将其生产的牛皮癣治疗药物“瑞体肤(Raptiva)”撤出市场。 相似文献
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在医学科学主义至上的今天,在冰冷的医疗器械和实验数据面前,国外的家庭医生对待病人的态度却让人感到温暖。任何时候,医生首先应该是一个朋友,一个知己! 相似文献
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在很长的历史时期内,精米白面都是富足生活的标志。到了现代,尤其是那些经济发达的地区,精米白面又成了不健康食品的代表。在美国的膳食推荐里,就主张用全谷食物来代替精米白面。对中国人来说,更熟悉的用语是粗粮。那么,粗粮和全谷食物有什么区别?一度被当作贫穷象征的它们,又是如何实现华丽转身的呢? 相似文献
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“一个公司的发展史就是一部产业的发展史”,没有比这句话更适合用来描述健安喜(General Nutrition Centre:GNC)的了.在时代和生活方式的变迁中探求健康的真谛,在经济的潮涨潮落里挖掘财富、洞悉最细微的顾客需求,驾驭最变幻的商业风云,秉承着经营健康、健康经营的经略,80年来,健安喜始终雄踞保健品产业潮流之先,织就了自己“当今世界上最大的保健品专卖店零售商和专业的保健品生产商“的宏伟蓝图. 相似文献
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肝炎患者常伴多种维生素及微量元素缺乏,应注意补充,以保护肝功能。肝炎患者的平衡膳食供给是保证多种维生素和微量元素摄入’的重要前提,不可忽视。 相似文献
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学子营养健脑,商家大桶掘金,看似双赢的"高考保健经济",仍需谨慎对待。6月初的高考如同背水一战,十年寒窗只为金榜题名。在最后复习冲刺的时段,有些学生甚至一天只睡四五个小时,就为了多记几个单词、多做几道习题。家长看在眼里,疼在心里,又不好说"不要复习了",于是,买来各种各样的高考保健品"侍候"孩子,给孩子又补"元气"又"健脑"。由此,敏锐的商家在高考中发现了商机,纷纷掘金高考保健品市场,通过各种途径告诉家长,学生一定要健脑。吃补脑产品"健脑"了,脑袋 相似文献
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F L Smith D S Yu D G Smith A P Leccese W H Lyness 《Pharmacology, biochemistry, and behavior》1986,25(4):849-855
Previously, it had been shown that lesions of cerebral 5-hydroxytryptamine (5-HT)-containing neurons and injections of drugs affecting 5-HT synthesis or receptor mediated function would alter amphetamine self-administration in the rat. The present study sought to ascertain whether diets enriched in L-tryptophan (L-TRY), the amino acid precursor to 5-HT, would: elevate cerebral 5-HT concentrations and affect amphetamine self-administration behavior. Diets containing 2.0 and 4.0% L-TRY increased cerebral 5-HT concentrations above those of rats on normal rat chow (0.26% L-TRY). The 4.0% diet elevated brain 5-HT to the same degree in rats exposed to the diet for 1, 2 or 3 days. When normal diets were restored, brain 5-HT concentrations rapidly returned to normal. Animals trained to self-administer d-amphetamine, when given access to the L-TRY enriched diets, significantly reduced their daily amphetamine self-injection during exposure periods. When normal rat chow was restored a delay in recovery to pre-diet amphetamine self-administration was observed: 1 day with the 2.0% L-TRY diet and 2 days with the 4.0% L-TRY diet. The 4.0% L-TRY diet failed to alter saline-frustration responding indicating the diet did not produce decrements in motor performance. When animals were placed on the 4.0% L-TRY diet and allowed access to amphetamine for 1 day then exposed to saline, a profound decrease in saline-frustration responding was observed.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
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Burdock GA 《Regulatory toxicology and pharmacology : RTP》2000,31(1):68-76
The demand for dietary supplements by the public has transformed this once cottage industry into a 12-billion-dollar-per-year business. Restrictive actions against dietary supplements by the Food and Drug Administration (FDA) prompted Congress to enact new and more permissive amendments governing dietary supplements (Dietary Supplement Health and Education Act, DSHEA) to the Federal Food, Drug and Cosmetic (FFD&C) Act in 1994. A comparison is made between the present status of dietary supplement regulation and the concept of general recognition of safety (GRAS) under conditions of intended use as set forth by the landmark 1958 Food Additive Amendment to the FFD&C Act. An argument is posited for use of applicable principles learned in nearly 40 years of experience with determining the GRAS status for hundreds of substances to problems posed by dietary supplements. 相似文献
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Several dietary supplements claim medicinal benefits due to their composition in hydrophilic and lipophilic molecules, natural extracts or synthetic compounds with antioxidant properties. In the present work, the antioxidant activity of selected supplements taken in pills, capsules or infusions were studied either individually or combined. Linear discriminant analysis (LDA) was used to categorize the condensed formulations (pills and capsules), infusion bags and combined samples according with their antioxidant activity measured by radical scavenging activity, reducing power and lipid peroxidation inhibition using brain homogenates as models. AAF proved to have the highest antioxidant activity in all the assayed methods, either singly taken or included in mixtures. Furthermore, the mixtures containing this supplement revealed synergistic effects in 92% of the cases. The intake of antioxidant mixtures might provide some additional benefits. 相似文献
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Wollschlaeger B 《International journal of toxicology》2003,22(5):387-390
The Dietary Supplement and Health Education Act (DSHEA) of 1994 was intended to ensure consumer access to safe dietary supplements, e.g., herbs, minerals, and vitamins. It granted the Food and Drug Administration (FDA) considerable enforcement authority to regulate dietary supplement industry. This article discusses relevant components of the DSHEA, explains the division of regulatory responsibilities between the FDA and the Federal Trade Commission (FTC), and refutes the often cited allegation that the herb and dietary supplement industry are unregulated. 相似文献
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Dietary calcium and magnesium supplements in spontaneously hypertensive rats and isolated arterial reactivity. 下载免费PDF全文
H. Mkynen M. Khnen P. Arvola H. Wuorela H. Vapaatalo I. Prsti 《British journal of pharmacology》1995,115(8):1455-1462
1. High calcium diet attenuates the development of hypertension but an associated undesirable effect is that Mg2+ loss to the urine is enhanced. Therefore, we studied the effects of high calcium diet alone and in combination with increased magnesium intake on blood pressure and arterial function. 2. Forty-eight young spontaneously hypertensive rats (SHR) were allocated into four groups, the dietary contents of Ca2+ and Mg2+ being: 1.1%, 0.2% (SHR); 2.5%, 0.2% (Ca-SHR); 2.5%, 0.8% (CaMg-SHR); and 1.1%, 0.8% (Mg-SHR), respectively. Development of hypertension was followed for 13 weeks, whereafter electrolyte balance, lymphocyte intracellular free calcium ([Ca2+]i), and mesenteric arterial responses in vitro were examined. Forty normotensive Wistar-Kyoto (WKY) rats were investigated in a similar manner. 3. Calcium supplementation comparably attenuated the development of Lypertension during normal and high magnesium intake in SHR, with an associated reduced lymphocyte [Ca2+]i and increased Mg2+ loss to the urine. 4. Endothelium-dependent arterial relaxation to acetylcholine was augmented in Ca-SHR and CaMg-SHR, while the relaxations to isoprenaline and the nitric oxide donor SIN-1 were similar in all SHR groups. Relaxation responses induced by the return of K+ to the organ bath upon precontractions in K(+)-free solution were used to evaluate the function of arterial Na+, K(+)-ATPase. The rate of potassium relaxation was similar in Ca-SHR and CaMg-SHR and faster than in untreated SHR.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
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Laura Boehnke Michaud Julie Phillips Karpinski Kellie L Jones Janet Espirito 《American journal of health-system pharmacy》2007,64(5):467-480
PURPOSE: The risks and key concepts regarding the use of dietary supplements in patients with cancer are described. SUMMARY: There are six common characteristics of dietary supplements that must be addressed when used by patients with cancer. Clinicians must establish if the supplement is an antioxidant, is an anticoagulant or procoagulant, has immunosuppressive or immunomodulating properties, has hormonal properties, has known safety issues, and has known or theoretical drug interactions. These six characteristics of the dietary supplements commonly used by patients with cancer are reviewed to aid in the analysis of the scientific data and communication of the results with the patient or family members. A framework upon which clinicians can adequately help patients make informed decisions regarding the use of complimentary and alternative medicine and dietary supplements is also described. When evaluating the appropriateness of a supplement for use by a patient with cancer, clinicians must conduct a safety review (evaluate the six characteristics). If the supplement is considered safe, an efficacy review must be conducted, after which the clinicians can recommend the supplement's use, accept the patient's decision to use the supplement if no or inconclusive evidence exists, or discourage use if there is conclusive evidence supporting inefficacy. Available resources for locating information regarding dietary supplements are also discussed. CONCLUSION: Counseling patients with cancer about dietary supplements requires a systematic thought process that considers the available theories and data, as well as the patients' views about the agents. 相似文献