“调神止痛”针刺法治疗神经根型颈椎病临床疗效观察30例

目的比较"调神止痛"针刺法与普通针刺治疗神经根型颈椎病的临床疗效。方法将60例神经根型颈椎病患者随机分为治疗组与对照组。结果治疗组治愈25例,好转3例,未愈2例,总有效率93.3%;对照组治愈20例,好转6例,未愈4例,总有效率86.7%;结论 "调神止痛"针刺法治疗神经根型颈椎病临床疗效优于普通针刺,值得临床推广。     

温针灸治疗阳痿30例临床观察

目的：观察温针灸治疗对阳痿的有效治疗方法。方法：将60例患者随机分为2组,治疗组30例采用温针治疗,对照组30例单纯采用针刺治疗,比较2组的临床疗效。结果：治疗组治愈18例,好转10例,未愈2例;总有效率为93%;对照组治愈15例,好转6例,未愈9例,总有效率为70%。2组比较（P〈0.05）,差异有无统计学意义。结论：温针灸治疗疗效明显优于单纯针刺对照组。     

小针刀治疗屈指肌腱狭窄性腱鞘炎的疗效观察

目的:观察在手屈指肌腱狭窄性腱鞘炎治疗中运用小针刀后的临床疗效,探讨手屈指肌腱狭窄性腱鞘炎治疗中简便有效的临床方法。方法:将60例随机分为小针刀组及封闭组,小针刀组应用局部麻醉后用小针刀的刀刃纵向划拨开粘连、增厚、狭窄的屈指肌腱腱鞘从而达到治疗目的。结果:术后7 d小针刀组:治愈28例,好转1例,无效1例,总有效率为96.7%;封闭组:治愈8例,好转4例,未愈18例,总有效率为40%。结论:小针刀治疗手屈指肌腱狭窄性腱鞘炎创伤小,快速、简单,方便,治愈率高,相较封闭疗法,小针刀疗法是治疗手指屈肌腱狭窄性腱鞘炎的一种理想方法。     

针刺配合推拿治疗肩周炎102例疗效观察

目的观察针刺配合推拿治疗肩周炎的临床疗效。方法将204例肩周炎患者随机分为2组,治疗组予针刺配合推拿治疗,对照组采取针刺治疗。治疗2个疗程后,分别对2组患者进行疗效评定并对比分析。结果治疗组治愈63例,好转35例,未愈4例,总有效率为96.1%;对照组治愈40例,好转30例,未愈32例,总有效率为68.6%。2组总有效率比较差异有高度统计意义(χ2=17.19,P<0.01),表明治疗组临床疗效显著优于对照组。结论针刺配合推拿治疗肩周炎疗效确切,值得临床推广应用。     

针刺治疗胆心综合征临床疗效观察

目的:观察针刺治疗胆心综合征的临床疗效.方法:56例非手术治疗的胆心综合征患者采取随机分组的方法分为针刺治疗组28例,以针刺疗法治疗;对照组28例以常规西药消炎利胆、对症治疗等措施治疗.结果:针刺治疗组28例中治愈16例,好转10例,无效2例,总有效率92.86%.对照组28例中治愈12例,好转9例,无效7例,总有效率75.00%.两组患者有效率比较χ2=6.421,P<0.05.针刺治疗组疗效优于常规药物治疗组.结论:针刺治疗胆心综合征疗效显著,优于一般西药治疗效果.     

浮针疗法治疗30例落枕疗效观察

目的:观察浮针疗法治疗落枕的效果。方法:确诊的60例落枕门诊患者,按照就诊顺序随机分为治疗组30例与对照组30例,治疗组用浮针治疗,对照组行常规针刺治疗,日1次,共治疗1~3次。观察疗效及治疗前后的VAS评分。结果:浮针组22例治愈,6例好转,2例未愈,总有效率93%;常规针刺组10例治愈,12例好转,8例未愈,总有效率73%,两组疗效比较差异有统计学意义(P=0.000)。结论:浮针疗法治疗落枕比普通针刺有更好的疗效,且疗程短,痛苦小,操作简单。     

针刺配合骨质增生治疗机治疗腰椎间盘突出症的疗效观察

目的 观察针刺、电疗与综合治疗腰椎间盘突出症的临床疗效,寻找一种行之有效的治疗方法。方法腰椎间盘突出症患者316例,分为针刺组104例,电疗组100例,综合组112例。针刺组采用常规针刺治疗,每日1次,每次30min,10次为1个疗程,连续2个疗程;电疗组采用骨质增生专用治疗机治疗,每日1次,每次30min,10次为1个疗程,连续2个疗程;综合组采用针刺与电疗共同治疗,先针刺后电疗,每日1次,每次各30min,疗程同上,治疗后进行疗效评定。结果 针刺组临床治愈48例,好转34例,未愈22例,总有效率78.85％;电疗组临床治愈40例,好转34例,未愈26例,总有效率74％;综合组临床治愈74例,好转32例,未愈6例,总有效率94.64％。组间差异有显著性(P<0.05)。结论 综合治疗腰椎间盘突出症是一种行之有效的方法,值得推广应用。     

中西医结合治疗心绞痛疗效观察

目的:观察血府逐淤汤与单硝酸异山梨酯联合治疗心绞痛的临床疗效。方法:将108例冠心病心绞痛患者,随机分为治疗组56例与对照组52例。两组患者均服用单硝酸异山梨酯治疗,治疗组在此基础上加用血府逐淤汤。两组均以10d为1个疗程,连续使用2个疗程。结果:治疗组治愈26例,好转19例,未愈11例,总有效率80.36%;对照组治愈20例,好转12例,未愈20例,总有效率61.54%。两组比较差异有显著性(P<0.05)。结论:血府逐淤汤与单硝酸异山梨酯联合治疗心绞痛临床效果较好。     

毫火针结合新医正骨治疗梨状肌综合征的临床研究

目的：研究毫火针结合新医正骨治疗梨状肌综合征的临床疗效,验证其安全性,探讨毫火针结合新医正骨对梨状肌综合征患者的治疗效果。方法：观察组予针刺结合新医正骨疗法,对照组予针刺结合按摩治疗梨状肌综合征,每组各60例,治疗2个疗程结束后观测其症状变化情况,根据疗效判定标准判定其临床疗效。结果：观察组治愈45例,好转12例,未愈3例,治愈率75.0％,总有效率95.0％;对照组治愈29例,好转10例,未愈21例,治愈率48.3％,总有效率65.0％。两组治愈率、总有效率比较差异有非常显著性（ P ＜0.01）,观察组疗效明显优于对照组。结论：毫火针结合新医正骨疗法治疗梨状肌综合征,疗效显著、确切,安全。     

针刺结合中药蜡疗治疗腕管综合征

目的：观察针刺结合中药蜡疗联合疗法治疗腕管综合征的临床疗效。方法将符合试验纳入标准的40例腕管综合征患者随机分成治疗组和对照组,各20例。治疗组采用针刺结合中药蜡疗局部治疗,先中药蜡疗后针刺治疗,1次/ d,4周为1疗程,对照组予立舒（双氯芬酸钠凝胶）腕关节外用治疗。结果治疗组总有效率85%,明显高于对照组的50%（P ＜0.05）。结论针刺结合中药蜡疗治疗腕管综合征,能促进局部血液循环,减轻炎症反应,增强关节自身的新陈代谢,改善症状。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.