Problems of the pathogenesis of cor pulmonale in chronic nonspecific lung diseases

The article discusses the values of 22 external respiration indices reflecting the condition of the lung volumes and their ratios, the irregular distribution of the ventilation-perfusion ratios, the alveolar ventilation, the diffusion property of the lungs, and the gas composition of the alveolar air in patients with chronic nonspecific diseases of the lungs before and after the development of chronic cor pulmonale and in its stages of compensation and decompensation. Correlative and regressive analysis of the main pathogenetic mechanisms was conducted, making it possible to reveal the contribution made by each of them to the pathogenesis of cor pulmonale.     

细胞黏附分子与慢性肺源性心脏病

细胞黏附分子（CAM）具有介导细胞与细胞之间、细胞与细胞外基质（ECM）之间黏附及相互作用的功能。在慢性肺源性心脏病（CCP）的形成中。CAM通过影响慢性肺动脉高压的形成而发挥作用，是CCP的另一发病机制。抗细胞黏附分子治疗为CCP的治疗开辟了一条新途径。