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1.
中老年人椎体骨密度定量CT测定研究 总被引:1,自引:0,他引:1
目的探讨定量CT(quantitative CT,QCT)椎体骨密度(bone mineral density,BMD)测定在诊断骨质疏松症中的临床价值,分析骨质疏松发生率与年龄、性别的关系。方法对597例中老年无症状体检者进行BMD测定,其中男性356例,女性241例,年龄30~89岁,按年龄、性别分组,每10岁为一年龄段。将QCT扫描线分别定位于L1~4椎体中间层面,与椎体上下缘平行扫描。结果中老年人BMD随年龄增高而下降,本组骨质疏松症发生率,女性:50~59岁为54.05%,60~69岁为81.81%,70~79岁为94.74%,80~89岁为100%;男性:50~59岁为25%,60~69岁为50%,70~79岁为64.52%,80~89岁为90.91%。结论 QCT诊断骨质疏松症敏感、准确、重复性强,易于推广应用。骨质疏松症发生率与年龄增加有关,年龄越大,骨质疏松症发生率越高,女性显著高于男性。 相似文献
2.
目的 明确重庆地区人口跟骨超声骨密度检测参数的变化特点.方法 用定量超声骨密度仪对重庆地区2480例体检人员的跟骨进行测定,获得9个年龄组的骨质量指数(BQI)、超声速率(SOS)、宽波带超声衰减(BUA),并进行统计学分析.结果 女性各项参数值均显著低于男性,在30~39、50~59、60~69、70~79、80~89岁年龄段女性跟骨SOS较男性偏低,在40~49、50~59、60~69、70~79、80~89岁年龄段女性骨质疏松发生率高于男性,男女性跟骨SOS与年龄有关.结论 40岁以上女性及60岁以上男性进入骨量快速丢失期,应及早预防,并每年定期检查骨密度. 相似文献
3.
目的通过测定所得骨矿含量数值更好的评估骨强度,监测骨质疏松的发生、发展,提高高危患者骨折风险识别能力。方法选取吉林省2375例50—89岁体检者运用美国OSTEOMETER DTX200周围骨骨密度测量仪测量受检者非受力侧前臂桡尺骨远端三分之一处的骨密度、骨矿含量,应用采用SPSS 17.0软件分析处理,数据用X±S表示。进行统计分析。结果男性50~59岁年龄组OP发生率为9.33%,女性为7.38%;60~69岁男性OP发生率为18.59%,女性为26.26%;70~79岁男性OP发生率为40.00%,女性为55.90%;80岁以上男性OP发生率63.93%,女性为71.42%。结论提示随着年龄增加,男女骨密度及BMC均呈下降趋势,女性下降速度明显较男性快,OP发生率也随之增加,各年龄组之间OP发生率女性亦均高于男性;T值大于-1的受检者中有5.74%骨量丢失率在13%~24%之间,亦为骨量减少范围,这类人群远期骨质疏松症的发病率及骨折的发生率很高,故骨矿含量(BMC)在临床骨质疏松症的诊断、治疗、预防骨质疏松骨折发生等方面起着重要作用。 相似文献
4.
目的对筛查出的骨质疏松症者及低骨量者,分析其年龄、性别与低骨量和骨质疏松症发生率的关系。方法使用定量超声骨密度仪,对信阳市中心医院各科医师推荐的8000例门诊患者的右胫骨中段进行超声定量检查分析。结果骨质疏松症发生率为女28.83%(50岁以上40.53%,60岁以上65.71%,70岁以上85.7%),男19.31%(50岁以上29.03%,60岁以上55.78%)。女性与男性之间相比,差异有显著性意义(χ^2=3.2、4.5,P〈0.01);50岁以后的女性,骨超声传导速率随年龄增高而下降。结论骨质疏松症发生率与增龄有关,年龄越大,骨质疏松症发生率越高。女性明显高于男性,低骨量者明显高于骨质疏松者。 相似文献
5.
目的 调查大庆市1096例健康汉族人群骨密度,了解该地区健康人群骨量峰值、骨密度变化的规律及骨质疏松发生率。方法 采用美国GE公司生产的Luner Prodigy Advance型骨密度仪,检测受试者腰椎和股骨颈骨密度(BMD)。将1096例检测结果按不同性别每5岁为1年龄组,应用SPSS19.0软件统计分析骨密度测量指标及骨质疏松(OP)发生率。结果 大庆市汉族男、女性人群腰椎骨密度峰值分别为1.197±0.203、1.192±0.145,股骨颈骨密度峰值分别为0.977±0.157、0.918±0.128。其峰值骨量年龄男性为45~49岁,50岁以后开始缓慢下降。其峰值骨量年龄女性为40~49岁,50岁以后开始缓慢下降。50~54岁年龄段男性骨质疏松症发生率为5.56%,女性为5.67%;55~59岁年龄段男性骨质疏松症发生率为7.32%,女性为11.51%;60~64岁年龄段男性骨质疏松症发生率为15.15%,女性为28.28%;65~69岁年龄段男性骨质疏松发生率为26.67%,女性为29.41%;70~74岁年龄段男性骨质疏松发生率为25.00%,女性为44.44%;75~79岁年龄段男性骨质疏松发生率为36.36%,女性为77.78%;80岁以上男性骨质疏松发生率为66.67%,女性为83.33%。结论 大庆市汉族人群不同年龄及同年龄组两性之间比较骨密度测定值差异显著(P<0.01)。55岁以后各年龄段女性骨质疏松发生率明显高于男性(P<0.01)。本研究报告的骨密度峰值大于沈阳地区,与合肥地区相近,略低于贵阳地区。OP发生率与合肥地区比较相近,略低于沈阳地区。 相似文献
6.
目的了解50岁以上体检人群局部肌肉含量(髋部、腰部)与相应骨密度变化趋势,分析不同年龄段局部肌肉含量与骨密度之间的相关性。方法收集苏州大学附属第二医院2008年6月至2013年12月50岁以上体检人群8 305例资料,整理双能X线骨密度仪(DXA)检测的骨密度数据(腰椎和髋部),同时整理每人"骨密度局部模式"所检测的"腰椎周围""髋部周围"肌肉比值数据;按性别分男女两组,两组再按年龄分为50~59、60~69、70~79、≥80岁四个亚组,用折线图显示局部肌肉含量及相应骨密度随年龄变化趋势,用偏相关分析、多元线性回归方法分析局部肌肉含量与相应骨密度的关系。结果①髋部肌肉含量与股骨颈骨密度关系:50~59、60~69岁两个年龄段中,男性及女性具有正相关,有统计学意义(P0. 05); 70~79、≥80岁两个年龄段中,男性及女性无相关性;②腰部肌肉含量与腰椎骨密度关系:仅在男性70~79岁年龄段中具有负相关关系(P0. 05),其余各组无相关性。结论 50岁以上人群中,在70岁之前,髋部肌肉含量对股骨颈骨密度影响显著,70岁之后,髋部肌肉含量对股骨颈骨密度影响不显著;所以,在肌少症与骨质疏松症相关范畴,建议50~70岁人群应关注下肢肌肉含量提高,以利骨量提高; 70岁以上老年人群,应更关注下肢肌肉含量之外骨质疏松症危险因素预防。 相似文献
7.
目的应用DEX200双能X线骨密度仪分析中老年人周围骨骨密度的测量结果。方法所选对象为哈尔滨地区及附近农村、郊区的中老年人,共3432例。年龄范围为40~79岁,每10岁为一个年龄段,分为4组。诊断标准:采用世界卫生组织(WHO)批准的诊断标准:T值≤-2.5标准差(SD)诊断为骨质疏松症;T值≥-1.0SD为骨量正常,-2.5SD相似文献
8.
目的调查北京地区健康体检人群骨密度的情况以及骨量减少和骨质疏松的患病率,为骨质疏松症的防治提供参考。方法选择2017年1月至2018年12月在中日友好医院健康体检中心进行健康体检的人群,排除继发性骨质疏松症及其他影响骨代谢的因素,共3859名。其中男性2067名,女性1792名。年龄20~83岁,平均年龄(51.29±11.18)岁,按性别及年龄每10年一组。采用美国GE公司的LUNAR Prodigy双能X线骨密度仪测量受试者腰椎1~4正位及股骨颈和全髋的骨密度。分析各组不同部位骨密度情况及骨量异常(包括骨量减少和骨质疏松)的患病率。采用SPSS 22.0统计软件进行分析,以P<0.05为差异有统计学意义。结果①男性腰椎1~4骨密度峰值在20~29岁,股骨颈和全髋骨密度峰值在30~39岁。女性各部位骨密度峰值均在30~39岁。②随年龄增长,男性和女性骨量异常患病率均呈上升趋势,50岁以上女性骨量异常患病率显著上升,明显高于同年龄组男性。③30~59岁男性和女性腰椎骨量异常患病率均明显高于髋部;70岁以上男性和60岁以上女性髋部骨量异常患病率明显高于腰椎。结论中老年人群尤其是绝经后女性是骨质疏松症的高危人群;老年人群的骨质疏松筛查可以考虑选择髋部骨密度为主。 相似文献
9.
目的调查大庆地区60岁以上老年人对骨质疏松的认知情况及骨质疏松患病率。方法对来我院就诊的361名60岁以上患者进行骨质疏松危险因素问卷调查,并行骨密度检查。骨密度检查采用美国GE公司生产的Luner Prodigy Advance型骨密度仪,检测受试者腰椎和股骨颈骨密度。将361例检测结果按不同性别每5岁为一年龄组,应用SPSS19.0软件统计分析骨密度测量指标及骨质疏松患病率。结果大庆地区60岁以上老年人对于骨质疏松危险因素的知晓率由高到低依次是钙饮食少或素食40.2%,长期使用激素34.9%,光照少29.9%,运动少25.5%,吸烟16.1%,饮酒15.5%,身体瘦小7.2%,骨质疏松家族史6.1%,肝肾功能不全4.2%,器官移植1.4%,绝经后或绝经过早1.1%。60~64岁年龄段男性骨质疏松症发生率为15.2%,女性为28.3%;65~69岁年龄段男性骨质疏松发生率为26.7%,女性为29.4%;70~74岁年龄段男性骨质疏松发生率为25.0%,女性为44.4%;75~79岁年龄段男性骨质疏松发生率为36.4%,女性为77.8%;80岁以上男性骨质疏松发生率为66.7%,女性为83.3%。结论大庆地区60岁以上人群对于骨质疏松危险因素的知晓率较低,骨质疏松患病率较高,提醒广大医务工作者应广泛开展骨质疏松健康教育。 相似文献
10.
目的调查北京地区9103例体检人群骨密度,探讨本地区原发性骨质疏松症流行病学情况。方法选择2012年3月-7月在我院体检的9103例汉族体检人群为研究对象,年龄16~93岁,采用韩国osteosys公司生产的ExA-3000型骨密度仪,检测受试者非受力侧前臂尺桡骨中远端1/3处骨密度,建立信息采集表,记录体检人群骨密度、身高、体重、体重指数(BMI)等情况,将检测结果以每10岁为一年龄段分组,分析每组骨密度、t、z评分、患病率及相关影响因素。结果北京地区男性、女性峰值骨量均发生在30~39岁年龄段,骨峰值分别为0.528±0.072、0.451±0.067,随着年龄的增长,骨密度逐渐降低,骨质疏松症发病率逐年增高;男性、女性30岁以前骨密度分别为0.47±0.107、0.436±0.060,骨质疏松症发病率分别为21.88%、1.33%;30~39岁骨密度分别为0.528±0.072、0.451±0.067,骨质疏松症发病率分别为7.31%、1.71%;40~49岁骨密度分别为0.52±0.071、0.445±0.065,骨质疏松症发病率分别为9.88%、2.3%;50~59骨密度分别为0.49±0.076、0.396±0.082,骨质疏松症发病率分别为20.83%、18.94%;60~69岁骨密度分别为0.463±0.085、0.328±0.071,骨质疏松症发病率分别为35.49%、52.21%;70~79岁骨密度分别为0.416±0.086、0.268±0.072,骨质疏松症发病率分别为57.31%、77.59%;80岁以上骨密度分别为0.384±0.091、0.222±0.059,骨质疏松症发病率分别为71.37%、95.24%。低BMI人群骨质疏松症发病率明显高于正常和高BMI人群,差距具有统计学意义(P0.05)。结论峰值骨量过后,随着年龄的增加,骨密度均呈下降趋势,骨质疏松症发病率显著上升,且女性绝经后骨量丢失明显加快,骨质疏松症发病率较同龄男性明显升高,差异具有统计学意义(P0.05)。值得关注的是,30岁以前的年轻男性骨密度状况也并不理想,可能跟工作繁忙,生活压力大,缺乏锻炼,生活方式不健康有关。因此,将骨密度检测作为中老年人体检的常规检查项目,早期发现,积极干预,同时加强年轻人群的健康宣教,倡导健康生活方式,提高峰值骨量,对于防治骨质疏松症具有重要意义。 相似文献
11.
Osteoporosis in patients on long-term home parenteral nutrition: a longitudinal study. 总被引:4,自引:0,他引:4
M Cohen-Solal C Baudoin F Joly K Vahedi L D'Aoust M C De Vernejoul B Messing 《Journal of bone and mineral research》2003,18(11):1989-1994
The prevalence of osteoporosis was investigated in 88 patients with intestinal failure (IF). Osteoporosis was found in 67%, dependent of body mass index and age when IF occurred. In 56 patients on HPN, followed prospectively, changes in bone density were dependent on the duration of HPN; older patients had a higher increase. INTRODUCTION: It has been suggested that low bone mass and negative bone balance may occur in adult patients receiving home parenteral nutrition (HPN). The aim of this study was to assess prospectively the prevalence of osteoporosis in intestinal failure (IF) patients and the changes in bone mineral density in those on long-term HPN and to analyze the factors that may influence the occurrence and evolution of osteoporosis. MATERIALS AND METHODS: Bone mineral density was measured at the lumbar spine and femoral neck in 88 IF patients. RESULTS: At the first bone mineral density determination (baseline), the prevalence of osteoporosis was 67% in this population (median age, 52 years). Ten percent of the patients with osteoporosis experienced fragility fractures. Osteoporosis was independent of age and gender but occurred earlier in patients who had received corticosteroids. At baseline, the lumbar Z-score was positively correlated mainly to body mass index and age when IF occurred; these two parameters explained 34% of the Z-score. Repeated measurements were performed in 56 patients during long-term HPN (mean duration, 5.5 +/- 1.2 years). The changes in Z-score at the lumbar spine were dependent on the age when IF occurred and on the duration of HPN, with a synergistic effect between them. The older the patients, the higher the increase in Z-score during HPN. CONCLUSION: HPN had no deleterious effect on cortical bone and actually improved trabecular bone in patients whose intestinal disease started after the age of 21 years. 相似文献
12.
Sarath Lekamwasam Lalith Wijayaratne Mahinda Rodrigo Udual Hewage 《Archives of osteoporosis》2009,4(1-2):79-84
Summary
This study, based on phalangeal bone mineral density (BMD) of 1,174 community dwelling male volunteers aged 50 years or more from seven provinces in Sri Lanka, shows 5.8% prevalence of osteoporosis among them. Advancing age, less physical activity, and low body weight were associated with low BMD. Men with larger families were more likely to have a lower bone mineral density.Purpose
The prevalence of osteoporosis among Sri Lankans is not well-known. We wished to estimate the prevalence and determinants of osteoporosis among older men in Sri Lanka.Methods
One thousand one hundred seventy-four healthy, community dwelling male volunteers, aged 50 years or more from seven out of nine provinces in Sri Lanka underwent phalangeal bone mineral density estimation using an AccuDXA® scanner. We calculated T scores using the local reference data, and subjects with T score equal or less than ?2.5 was considered to have osteoporosis.Results
Sixty-six men (5.8%) were detected to have osteoporosis. In contrast to men in the highest tertile of bone mineral density, men in the lowest tertile were older (60.0 versus 55.8 years, p?<?0.001), lighter (56.3 versus 65.6 kg, p?<?0.001), less physically active (16.1% versus 5.5%, p?<?0.001) and had larger families consisting of four or more children (36% versus 20.9%, p?<?0.001). Smoking, alcohol, or milk consumption showed no association with bone mineral density.Conclusions
We report 5.8% prevalence of osteoporosis among men older than 50 years in Sri Lanka, and advancing age, less physical activity, and low body weight were associated with low bone mineral density. Men with larger families were more likely to have a lower bone mineral density. 相似文献13.
Hongfu Wang Guoying Zhu Yongxin Shi Shifang Weng Taiyi Jin Qinghu Kong Gunnar F Nordberg 《Journal of bone and mineral research》2003,18(3):553-560
Cadmium may have both direct and indirect effects on bone turnover. It is nephrotoxic and can interfere with vitamin D metabolism. Such perturbation may result in osteoporosis and osteomalacia. In this study, a total of 790 persons (302 males and 488 females) participated; they were all over 35 years old and resided in an area near a cadmium smelter in southeast China. All participants completed a questionnaire, and bone mineral density was measured by SPA-4 single-photon absorptiometry at the radius and ulna. Cadmium content of urine was determined by graphite-furnace atomic absorption spectrophotometry as a measure of dose. The decline in bone mineral density with age in a heavily polluted area was greater than that in a control area for subjects over 60 years of age of both sexes (p < 0.05). In single regression, forearm bone densities were negatively correlated with urinary cadmium excretion in both males and females (p < 0.001), whereas stepwise regression showed that forearm bone density decreased linearly with age (p < 0.001) and urinary cadmium (p < 0.01) in both sexes, suggesting a dose-effect relationship between cadmium dose and bone mineral density. Based on the World Health Organization criteria, (bone mineral density < -2.5 SDs below the normal young adult), the prevalence of osteoporosis in women increased from 34.0% in the control area to 51.9% in the heavily polluted area (p < 0.01) among subjects over 50 years old, and the odds ratio value was 2.09 (95% CI: 1.08-4.03) for the highly polluted area compared with the control area. A striking observation in the study was the marked increase of the prevalence of fracture in the cadmium-polluted area in both sexes. It was concluded that environmental exposure to cadmium is associated with an increased loss of bone mineral density in both males and females, leading to osteoporosis and increased risk of fractures, especially in the elderly and in females. 相似文献
14.
目的 探讨男性体检人群血清尿酸(serum uric acid, SUA)水平对前臂骨密度(bone mineral density, BMD)的影响及SUA与体质量指数(body mass index, BMI)对BMD影响的交互作用。方法 选取2020年1~12月于河北省人民医院体检中心进行年度体检的50岁及以上的2270名男性。采用双能X线骨密度仪测定非优势侧前臂桡骨远端1/3处BMD值,计算T值,根据T值分为骨量正常组、骨量减少组和骨质疏松组。SUA水平在正常范围者按四分位分为Q1~Q4组,高于正常范围者为Q5组。探讨各组SUA变化及与BMD的关系,分析骨量异常的影响因素,建立相乘和相加效应模型分析影响因素间的交互作用。结果 骨质疏松组SUA水平低于骨量正常组和骨量减少组,Q1~Q5组BMD值、T值、骨量减少患病率、骨质疏松症患病率比较差异均有统计学意义(P<0.05)。双变量相关性分析显示,BMD值、T值均与SUA呈正相关性(P<0.05)。有序多分类Logistic回归分析显示,年龄、收缩压(SBP)、患有高血压与骨量异常的风险呈正相关性,BMI、SUA与骨量异... 相似文献
15.
目的 调查长春市16019例汉族人群骨密度,分析本地区峰值骨量及骨密度变化的人群规律.方法 采用美国Osteometer Medi Tech公司生产的DTX-200型骨密度仪,检测受试者非受力侧前臂桡尺骨远端三分之一处骨密度(BMD).将16019例检测结果按不同性别每5岁为一年龄组,应用SPSS 13.0软件统计分析骨密度均值、T评分及骨量丢失百分率.结果 长春市男、女性人群骨密度峰值分别为0.625±0.109、0.506±0.058,其峰值年龄为30~39岁年龄段,40岁以后开始缓慢下降,50~59岁年龄段男性骨质疏松发病率为7.7%,女性为6.97%;60~69岁年龄段男性骨质疏松发病率为18.13%,女性为35.97%;70~79岁年龄段男性骨质疏松发病率为36.41%,女性为59.55%,80岁以上男性骨质疏松发病率为57.53%,女性为75.56%.结论 不同年龄及同年龄组两性之间比较骨密度测定值差异显著(P<0.01).50岁以后各年龄段女性骨质疏松发病率明显高于男性(P<0.01).本研究报告的骨密度峰值高于日本、丹麦同类型骨密度仪检测结果;与北京地区骨密度检测结果相近.与西双版纳傣族、西藏、甘肃东乡族比较,差异显著(P<0.01). 相似文献
16.
目的 调查北京昌平地区60岁以上老年人的骨质疏松情况.方法 采用随机整群抽样调查,抽取昌平地区992名60岁以上老年人测量前臂骨骨密度并问卷调查一般情况.结果 昌平地区60岁以上人群总体骨质疏松率为49.19%,男性为9.68%,女性为39.92%.总体骨密度平均T值为-1.8998,男性为-1.1416,女性为-2.2812,随年龄的增加,整体骨质疏松发病率也在增高,女性骨量减少和骨质疏松发生率均高于男性,而且女性在60~69岁之间骨量减少高于其他年龄段.骨折与骨密度呈负相关关系,而骨密度与性别、体重、身高、年龄、饮酒均有关.结论 北京昌平地区60岁以上的老年人骨质疏松发生率较高,提醒广大医务工作者应广泛开展骨质疏松健康教育. 相似文献
17.
目的观察成都市城区健康人群骨密度变化规律,建立该型骨密度仪成都地区骨密度正常值,为骨质疏松诊断、防治提供参考依据。方法①采用EXPERT-XL双能X线骨密度仪(美国 LUNAR公司生产)测定成都市城区健康体检者771例,其中男性300例,女性471例,测量部位包括腰椎1~4和髋部;②按年龄、性别分别输入数据,以10岁为一年龄组,分别计算各组骨密度值,结果以x-±s表示。结果男性腰椎及股骨近端骨密度峰值出现在30~39岁,女性腰椎及股骨近端骨密度峰值出现在20~29岁,随着年龄增加,骨密度逐渐降低,男性在70岁后腰椎骨密度有反弹,而女性在50~59岁间骨密度下降迅速。结论本组健康人群骨密度数据将为成都地区骨质疏松诊断、防治提供参考依据;分析男性腰椎骨密度时应结合股骨近端骨密度;女性50岁后应注意预防、治疗骨质疏松,男性骨质疏松不容忽视。 相似文献
18.
目的为了解广州地区正常人群骨密度(BMD)的变化规律和骨质疏松(OP)的患病率.方法采用美国Lunar公司的双能X线骨密度仪对广州地区1 530名20~89岁居民进行腰椎2-4和髋部骨密度测量.结果男性腰椎骨密度峰值在20~29岁,女性腰椎骨密度峰值在30~39岁,男性与女性髋部骨密度峰值均在30~39岁,峰值后随年龄增加而骨密度下降,女性在50~59岁出现明显加速,男性没有加速下降现象.广州地区男性50~89岁骨质疏松患病率26.53%,女性50~89岁骨质疏松患病率42.64%,两者之间差异有非常显著性(P<0.01).结论广州地区女性骨质疏松患病率高于男性,预防骨质疏松的重点在女性,但对男性骨质疏松患者也不容忽视. 相似文献
19.
Seventy-six of 108 random men aged 50 years or over were evaluated for erectile dysfunction with interviews of patients using the International Index of Erectile Function Form and minimal evaluation. Serum hormone concentrations were measured. Bone mineral density was measured using dual energy x-ray absorptiometry. Hormone levels did not show significance in terms of erectile dysfunction or bone mineral density results. Erectile dysfunction was determined in 57 (75%) of 76 patients. Ten (13.2%) patients had osteoporosis and 45 (59.2%) had osteopenia at the bone mineral density measurements. The distribution of bone mineral density groups relating to erectile dysfunction did not show significance. The frequencies of osteoporosis and erectile dysfunction increased with age, but the association of these conditions seems to be independent of each other and hormonal changes appear not to be the major determinants for both conditions in elderly men. 相似文献
20.
Diane L Schneider Ricki Bettencourt Elizabeth Barrett-Connor 《Journal of clinical densitometry》2006,9(3):255-260
It is common clinical practice to obtain a bone density measurement at both the hip and spine to evaluate osteoporosis. With aging, degenerative changes in the lumbar spine may elevate the bone mineral density (BMD) results giving false assurances that the fracture risk at the spine is low. We examined the association of spine osteoarthritis and bone mineral density in 1082 community-dwelling ambulatory older women aged 50-96 years who participated in a 1992-1996 osteoporosis research clinic visit. The BMD was measured at the hip and posteroanterior (PA) and lateral lumbar spine using dual energy X-ray absorptiometry (DXA). Spine osteoarthritis was identified on the PA lumbar spine DXA images by a musculoskeletal radiologist. Forty percent of women had evidence of spine osteoarthritis (OA). Women with spine OA had a mean age of 77.4 yr (95% confidence interval [CI]: 76.5-78.2), were significantly older than women without spine OA (mean age, 66.8 yr; 95% CI: 65.9-67.7), and were more likely to have prevalent radiographic fractures (14.2% vs. 9.5%; p<0.05). Age-adjusted BMD at the femoral neck, total hip, PA spine, and lateral spine was significantly higher in women with spine OA. Women with spine OA were more likely to have osteoporosis by the World Health Organization classification at the femoral neck and total hip than those without spine OA, but less likely based on the PA spine (14.4% vs. 24.5%). Despite higher BMD levels, women with OA of the lumbar spine had higher prevalence of osteoporosis at the hip and more radiographic vertebral fractures. In elderly women 65 yr and older who are likely to have spine OA, the DXA measurement of the spine may not be useful in assessing fracture risk, and DXA of the hip is recommended for identification of osteoporosis. 相似文献