共查询到20条相似文献,搜索用时 0 毫秒
1.
Disseminated, nonmeningeal gastrointestinal cryptococcal infection in an HIV-negative patient 总被引:1,自引:0,他引:1
J S Daly K A Porter F K Chong R J Robillard 《The American journal of gastroenterology》1990,85(10):1421-1424
Gastrointestinal cryptococcosis is extremely rare, especially in patients with no involvement of the central nervous system. We describe a 63-yr-old man undergoing prednisone therapy for chronic hepatitis and cirrhosis who presented with peritonitis, colitis, and skin lesions. Pathological studies revealed necrosis and numerous cryptococcal organisms in the colon, omentum, and skin, and cultures yielded Cryptococcus neoformans. The patient died of multisystem organ failure following emergency exploratory surgery performed when he had onset of symptoms of a bowel perforation after an endoscopic biopsy. Clinicians should be aware that gastrointestinal cryptococcosis can occur in the absence of infection of the central nervous system or lungs, and that it may affect relatively healthy patients who are immunocompromised because of splenectomy, chronic liver disease, or steroid therapy. 相似文献
2.
3.
4.
M. Pynka M.D. A. Wnuk M.D. D. Bander M.D. M. Syczewska M.D. A. Boroń M.D. Ph.D. B. Prost M. Sc. S. Wrzecion M.D. 《Infection》1998,26(3):184-186
A 47-year-old man with acquired immune deficiency syndrome was found to have disseminatedSaccharomyces kluyveri infection. The yeast was isolated from blood and cerebrospinal fluid. An autopsy revealed the presence of the microorganism in many organs including liver, kidneys, pancreas, spleen, lung, and brain. The case confirms a potential pathogenicity of yeasts of the genusSaccharomyces in patients with profound immune deficiency, especially in advanced HIV infection. 相似文献
5.
Sumihisa Imakado Yuichi Kojima Toru Hiyoshi Shuhei Morimoto 《Diabetes research and clinical practice》2009,83(2):e35-e36
A patient with diabetic nephropathy who presented with multiple tender subcutaneous nodules caused by Mycobacterium marinum infection is presented. 相似文献
6.
《Hematology/oncology and stem cell therapy》2017,10(2):89-92
Infections with rapidly growing mycobacteria are rare and most often seen in immunocompromised patients. We herein present the case of a 69-year-old man with a T-cell lymphoma treated by chemotherapy and mogamulizumab with a 6-month history of febrile episodes and subcutaneous nodules in both arms and arthritis of metacarpophalangeal joints. Blood cultures and DNA sequencing results demonstrated the growth of Mycobacterium chelonae. The patient was successfully treated with clarithromycin, moxifloxacin, and tobramycin, but died shortly after due to lymphoma progression. 相似文献
7.
8.
9.
10.
A 60-year-old woman with non-Hodgkin's lymphoma was admitted to the hospital because of extensive subcutaneous abscesses developing
on all limbs. The patient had an aquarium and kept tropical fish as pets. After repeated investigations, the diagnosis of
Mycobacterium marinum was established from skin biopsy by PCR and culture. Long-term therapy with several drugs regimens had only a limited efficacy
and was accompanied by severe adverse reactions. This report highlights the therapeutic problems posed by disseminated cutaneous
M. marinum infection in the immunosuppressed host.
Received: July 3, 2001 · Revision accepted: August 19, 2002
Ruxandra Enzensberger (corresponding author) 相似文献
11.
12.
P. ENGERVALL MD M. BJÖRKHOLM B. PETRINI N. HEURLIN B. HENRIQUES G. KÄLLENIUS 《Journal of internal medicine》1993,234(2):231-233
Abstract. Mycobacterium malmoense is an atypical mycobacterium previously isolated from lymph nodes in children and from adults with pulmonary disease. Disseminated infection is extremely rare and bone marrow involvement has never previously been described. We report a patient with chronic granulocytic leukaemia and persistent fever with granuloma in the bone marrow due to disseminated M. malmoense infection. The patient initially received treatment with isoniazid, ethambutol and rifampicin with clearance of mycobacteria in the bone marrow and clinical improvement. Sensitivity in vitro was established for streptomycin, amikacin, ethambutol and rifabutin. The patient eventually expired as a result of progressive respiratory failure from other opportunistic infections. At autopsy staining of samples from lung parenchyma revealed fungal hyphi but staining for Pneumocystis carinii and myobacteria were negative. 相似文献
13.
14.
15.
I. Cardeau‐Desangles A. Fabre O. Cointault J. Guitard L. Esposito X. Iriart A. Berry A. Valentin N. Kamar 《Transplant infectious disease》2013,15(3):E115-E118
Ochroconis gallopava is an emerging cause of mycosis in solid organ transplant recipients. Herein, we report a rare case of disseminated O. gallopava infection that involved lung, subcutaneous area, brain and peritoneum in a heart transplant recipient. Despite voriconazole therapy, the patient died 2 months after diagnosis. 相似文献
16.
17.
Tanaka Y Hori T Ito K Fujita T Ishikawa T Uchiyama T 《Internal medicine (Tokyo, Japan)》2007,46(13):1005-1009
A 54-year-old man was admitted to our hospital because of intermittent high fever, general malaise, cough and body weight loss after he had been examined and treated at the former hospital for 3 years without a definitive diagnosis and effective therapy. Bacterial examination on admission revealed Streptococcus pyogenes in peripheral blood, bone marrow aspirates and pleural effusion. Furthermore, Mycobacterium avium complex (MAC) was detected in sputum, gastric juice, bone marrow liquid, pleural effusion by acid-fast bacillus culture or polymerase chain reaction (PCR). Biopsy of the neck lymph node showed multiple granulomas and the presence of acid-fast bacilli. Administration of ABPC/SBT and later CLDM resulted in disappearance of Streptococcus pyrogenes after 2 weeks. We suspected of generalized immunodeficiency that might underlie the severe bacteremia/osteomyelitis and disseminated MAC infection. We tested interferon (IFN)-gamma production of peripheral blood mononuclear cells (PBMC) of the patient after phytohemagglutinin (PHA)-stimulation and found that these cells produced no or undetectable levels of IFN-gamma in the presence of autologous plasma while produced almost normal levels of IFN-gamma in the presence of healthy donor's plasma. Since this neutralizing activity was co-purified in the IgG fraction, the immunodeficient state of the patient seemed to be caused by autoantibody to IFN-gamma. As far as we know, this is the first report of a Japanese case of disseminated MAC infection presumably due to autoantibody to IFN-gamma. 相似文献
18.
19.
Disseminated Sporothrix schenckii infection with arthritis in a patient with acquired immunodeficiency syndrome 总被引:2,自引:0,他引:2
E Lipstein-Kresch H D Isenberg C Singer O Cooke R A Greenwald 《The Journal of rheumatology》1985,12(4):805-808
Patients with the acquired immune deficiency syndrome are susceptible to a wide spectrum of opportunistic infections. We report a 34-year-old man who developed systemic sporotrichosis involving the skin and joints, and whose illness terminated in subacute encephalopathy and Pneumocystis carinii pneumonia. Fungal arthritis is another infection to which patients with this syndrome are subject. 相似文献
20.
We report of a case of severe disseminated U. urealyticum infection in a 35-y-old kidney transplanted patient with CVID. Routine microbiological tests were negative. Six weeks after admission, abscess material was grown on Mycoplasma culture medium yielding U. urealyticum in high titres. The patient responded promptly to appropriate antibiotics. 相似文献