Brandt-Daroff习服法联合倍他司汀治疗良性阵发性位置性眩晕复位后残余症状的疗效分析

目的　观察Brandt-Daroff习服法,以及联合倍他司汀治疗良性阵发性位置性眩晕（BPPV）复位后残余症状的疗效。方法　纳入2017年3月～2019年3月收治BPPV复位成功患者,将其中复位后仍存在残余头晕患者75例随机分3个组,对照组（倍他司汀治疗）、训练组（Brandt-Daroff习服法）和联合组（Brandt-Daroff习服法联合倍他司汀）,每组25例。对所有患者治疗后残余症状持续时间,治疗前后的眩晕残障量表（dizziness handicap inventory,DHI）进行评分比较。结果　治疗前各组患者的基线资料及DHI评分差异无统计学意义（P＞0.05）。治疗后,联合组残余症状持续时间低于对照组和训练组（P＜0.05）,对照组和训练组之间差异无统计学意义（P＞0.05）;治疗7天后,联合组DHI评分低于训练组及对照组（P 均＜0.05）,训练组和对照组比较差异无统计学意义（P＞0.05）;治疗28天后,联合组DHI评分均低于对照组和训练组（P 均＜0.001）,训练组评分低于对照组,差异具有统计学意义（P＜0.001）。结论  Brandt-Daroff习服法联合倍他司汀能显著减轻BPPV成功耳石复位后残余的头晕症状,单用Brandt-Daroff习服法和常规内科药物倍他司汀有相似疗效。     

管石复位法治疗良性阵发性位置性眩晕

目的 探讨管石复位法治疗良性阵发性位置性眩晕(benign paroxysmal positional vertigo,BPPV)的效果与方法.方法 回顾分析了2006年4月至2010年3月间我院治疗的BPPV患者96例,其中男性34例,女性62例,年龄43～70岁(平均55.5岁),后半规管BPPV 78例,水平半规管BPPV 16例,同时合并同侧后、水平半规管BPPV 2例,分别采用Epley管石复位法、Barbecue翻滚疗法及Brandt-Daroff习服疗法治疗.结果 后半规管BPPV 78例,经用Epley管石复位法治疗1～3次眩晕消失;水平半规管BPPV 16例,14例采用Barbecue翻滚疗法治疗1～2次眩晕消失,2例复位4次仍有眩晕,考虑嵴顶结石症,改用Brandt-Daroff习服疗法治疗半月眩晕消失;2例同时合并同侧后、水平半规管BPPV患者各复位2次眩晕消失.结论 管石复位法治疗BPPV安全有效,可疑嵴顶结石症患者,改用Brandt-Daroff习服疗法治疗效果良好.     

家庭式改良Epley法补充性治疗后半规管BPPV的疗效观察

目的观察家庭式改良Epley法补充性治疗后半规管BPPV的疗效。方法将2019年1月～2019年6月三甲医疗机构确诊的80例后半规管BPPV患者按随机数据表法分为对照组和治疗组,每组40例,对照组:在三甲医疗机构眩晕专科医师给予患者传统Epley法治疗,治疗组:在三甲医疗机构模拟家庭环境,以医患共同参与的医疗模式给予改良Epley法治疗,如患者仍有残余头晕或者位置性眩晕复发,予补充家庭式改良Epley法自我复位治疗。统计两组患者治愈率,记录两组患者治疗1天及1周后眩晕残障量表(DHI)评分。结果治疗1天后,治疗组治愈率85%,对照组治愈率60%,治疗组治愈率明显高于对照组(P<0.05);治疗1周后,治疗组治愈率92.5%,对照组治愈率87.5%,两组治愈率相当(P>0.05);治疗1天后、1周后治疗组的DHI得分均低于对照组(P<0.05),两组复位治疗过程均未出现严重不良反应。结论家庭式改良Epley法能有效、安全的补充性治疗后半规管BPPV,这一医患共同参与的医疗模式值得在临床上推广。     

后半规管良性阵发性位置性眩晕三种自我治疗手法的疗效比较

目的 对后半规管良性阵发性位置性眩晕三种自我治疗手法(改良Epley法、改良Semont法和Brandt-Daroff法)进行临床疗效和复发率的对比研究.方法 168例患者随机抽签法分为四组,改良Epley组45例,改良Semont组43例,Brandt-Daroff组40例和对照组40例,对照组仅给予药物治疗不使用复位法.比较四组治疗1周和1个月时的疗效、不良反应发生率以及6个月时的复发率,并对四组达到治愈所需的时间进行比较.结果 改良Epley法治疗1周时疗效优于其他三组,差异具有统计学意义(x2=8.55、23.23及44.00,P值均＜0.01),1个月疗效优于Brandt-Daroff法(x2=8.42,P＜0.05).改良Semont法1周疗效优于对照组(x2=14.49,P＜0.01),1个月疗效与对照组比较差异无统计学意义(x2=0.01,P＞0.05).Brandt-Daroff法疗效较差,1周和1个月疗效与对照组比较,差异均无统计学意义(x2=3.35及0.18,P值均＞0.05).Kaplan-Meier生存曲线比较四组的治愈时间,经Log-rank检验分析,改良Epley组治愈时间短于其他三组,差异具有统计学意义(x2=10.850、25.779及35.085,P值均＜0.01).眩晕、恶心、呕吐、心悸等不良反应的发生率在三个物理治疗组间差异无统计学意义.治疗6个月时四组的复发率比较,差异无统计学意义(x2=4.076,P=0.253).Logistic回归分析显示,年龄和治疗前病程长短是复发的独立预测因素,而复位方法、性别、患侧、病因和发病次数等与复发无关.结论 改良Epley法在快速缓解后半规管良性阵发性位置性眩晕症状方面优于改良Semont法和Brandt-Daroff法,可作为反复发作患者的一线治疗选择,但该方法并不能降低复发率.     

Brandt-Daroff康复练习治疗水平半规管良性阵发性位置性眩晕

目的探讨Brandt-Daroff康复练习对23例水平半规管良性阵发性位置性眩晕患者的疗效。方法选取2007年3月~2013年12月间23例水平半规管良性阵发性位置性眩晕患者,包括2例主观性良性阵发性位置性眩晕和21例客观性水平半规管良性阵发性位置性眩晕患者,嘱患者进行Brandt-Daroff练习。结果 23例患者练习1周后,痊愈12例,9例症状减轻,2例无效;2周后复诊,痊愈17例,5例症状明显减轻,1例无效。结论 Brandt-Daroff康复练习治疗水平半规管良性阵发性位置性眩晕取得良好的疗效。     

Epley法和Semont法治疗后半规管良性阵发性位置性眩晕的疗效比较

目的探讨采用Epley管石复位法和Semont管石解脱法治疗后半规管良性阵发性位置性眩晕的疗效。方法将100例确诊为原发性后半规管良性阵发性位置性眩晕的患者随机分为Epley法组和Semont法组,Epley法组给予Epley管石复位法治疗,Semont法组给予Semont管石解脱法治疗,统计治疗1周后的疗效,并随访6个月。结果 Epley法50例,治愈40例,有效3例,无效7例,6个月后复发6例;Semont法50例,治愈31例,有效13例,无效6例,6个月后复发7例。治愈率:Epley法为80%,Semont法为62%,两组比较差异有统计学意义(χ~2=3.93,P0.05);总有效率:Epley法为86%,Semont法为88%,两组比较差异无统计学意义(χ~2=0.019,P0.05);6个月后复发率:Epley法为12%,Semont法为14%,两组比较差异无统计学意义(χ~2=0.019,P0.05)。结论Epley法治疗后半规管BPPV的短期治愈率明显高于Semont法,Epley法应被视为后半规管BPPV的一线首选治疗方法。     

继发于突发性聋的BPPV与原发性BPPV的疗效和转归比较

目的 回顾性分析继发于突发性聋的良性阵发性位置性眩晕(BPPV)与原发性BPPV的临床特点,比较两者疗效和转归,并分析可能的原因。方法 观察2019年12月—2021年12月就诊的突发性聋继发BPPV患者74例,与同期就诊的原发性BPPV患者112例进行比较。观察、比较突聋继发BPPV患者与原发性BPPV患者的临床分型、疗效、治疗后眩晕障碍量表(DHI)评分、治疗前血同型半胱氨酸(Hcy)数值的差异。结果 原发组中单管管石症80.4%(90/112),高于继发组33.8%(25/74),两者比较差异具有统计学意义(χ²=40.953,P<0.01);原发组1次治愈率86.6%(97/112),高于继发组50.0%(37/74),两者比较差异具有统计学意义(χ²=29.467,P<0.01);继发组1次治愈后眼震慢相速度CP值>20%为67.6%(25/37),高于原发组25.8%(25/97),两者比较差异具有统计学意义(χ²=20.002,P<0.01)。继发组治疗后DHI评分≤30分为31.1...     

手法复位结合中药治疗BPPV的疗效观察

目的探讨手法复位结合中药治疗良性阵发性位置性眩晕的临床应用价值。方法把75名后半规管型BPPV患者自愿选择分为2组,一组为观察组,一组为对照组,并签署知情同意书。治疗组40例,先行手法复位,再配合中药治疗2周,中药的使用根据病人的症状予以辩证施治。对照组35例,仅行单纯手法复位治疗。两组病人均随访6个月,分别于治疗后即刻,2周,1个月,6个月4个时间点作疗效评价。结果观察组治疗后即刻总有效率为90%(36/40),对照组治疗后即刻为91.4%(32/35)。两组比较,差异无统计学意义(P0.05)。观察组2周和1个月的总有效率分别为92.5%(37/40),和95%(38/40);对照组治疗2周和1个月的总有效率均为74.3%(26/35)。两组比较,差异均具有统计学意义(P0.05),观察组高于对照组。半年后,观察组复发率为5.26%(2/38),对照组为21.9%(7/32)。两组比较,差异具有统计学意义(P0.05),其复发率,观察组低于对照组。结论手法复位结合辨证应用中药治疗BPPV,能有效提高临床疗效,减少复发。     

良性阵发性位置性眩晕诊治分析

目的回顾性分析我科诊治的良性阵发性位置性眩晕(BPPV)患者,分析发病因素及治疗方式,旨在协助临床医生提高精准诊治。方法以眩晕问卷形式收集2010年6月-2016年11月接诊1200例BPPV患者,分别采用Epley复位法、Barbecue复位法、Semont复位法及Brandt-Daroff习服法,药物与心理辅助治疗。分析发病原因、临床特征、治疗方式。结果 1200例BPPV患者中,女性多见,男女比例为1:2.2;60-70岁年龄段发病多;症状仅表现为体位发作性眩晕,无基础病和合并症者多;诊断分型后半规管BPPV1012例(84.33%)、水平半规管BPPV162(13.50%)、上半规管BPPV0例(0.00%)、多个半规管BPPV26例(2.17%);耳石复位是首选治疗方法,首次复位有效率为88%。结论详细收集病史及临床特征,综合评估做出正确诊断,给予个性化治疗是有效治疗BPPV的关键。     

良性阵发性位置性眩晕的认知行为治疗

目的研究认知行为治疗在良性阵发性位置性眩晕(BPPV)治疗中的作用。方法24例确诊为BPPV且焦虑抑郁量表(HADS)评分提示有显著临床精神性症状的患者被随机分为观察组(手法复位+药物治疗+认知行为治疗)和对照组(手法复位+药物治疗),每组12例。在治疗前及治疗后2周分别进行眩晕残障程度评定量表(DHI)、焦虑抑郁量表(HADS)及视觉模拟量表(VAS)评估。结果治疗后,观察组与对照组DHI躯体评分无显著差异(2.00±1.48比2.50±1.51,P0.05);观察组与对照组DHI情感评分(3.50±1.93比6.00±3.52)、DHI功能评分(6.67±2.74比10.33±3.89)、HADS评分(7.17±1.99比10.58±4.50)及VAS评分(0.58±0.67比1.25±0.87)之差异均具有显著统计学意义,均P0.05。结论认知行为治疗可改善BPPV患者的情感及功能症状,缓解其焦虑、抑郁情绪,提高生活质量。     

Strategies to prevent recurrence of benign paroxysmal positional vertigo

OBJECTIVE: To determine if a daily routine of Brandt-Daroff exercises increases the time to recurrence and reduces the rate of recurrence of benign paroxysmal positional vertigo (BPPV). DESIGN: Random sample of convenience and retrospective case review. SETTING: Tertiary referral center and outpatient clinic. PATIENTS: One hundred sixteen patients diagnosed with BPPV involving the posterior semicircular canal (BPPV-PC) who were successfully treated with the canalith repositioning procedure. INTERVENTIONS: Patients in the treatment group (n = 43) performed daily Brandt-Daroff exercises, while patients in the no-treatment group (n = 73) performed no exercises. MAIN OUTCOME MEASURES: Follow-up was as long as 2 years. Every 2 months patients were mailed a questionnaire. If BPPV had recurred, patients contacted the principal investigator within 24 hours. Within 1 to 2 weeks, patients were evaluated in the clinic with the Dix-Hallpike maneuver or, if unable to travel to the clinic, interviewed by telephone. RESULTS: Symptoms recurred in 50 (43%) of the 116 subjects, 34 (47%) of 73 in the no-treatment group and 16 (37%) of 43 in the treatment group. There was no significant difference in the frequency of recurrence (Pearson chi(2), P = .33) or time to recurrence (survival analysis, log-rank test, P = .92). A history of recurrent BPPV-PC did not affect frequency of recurrence (Pearson chi(2), P = .33) or time to recurrence (survival analysis, log-rank test, P = .72). CONCLUSION: Our results suggest that a daily routine of Brandt-Daroff exercises does not significantly affect the time to recurrence or the rate of recurrence of BPPV-PC.     

难治性良性阵发性位置性眩晕的临床分析

目的 探讨难治性良性阵发性位置性眩晕(BPPV)的临床特点及治疗。 方法 回顾分析2014年8月至2016年1月诊断为难治性BPPV的13例患者的临床资料,分析其病因相关因素、类型、临床特点及治疗效果。 结果 13例难治性BPPV中,头部外伤为最常见因素,离地性水平半规管BPPV为最常见类型。根据病因积极治疗伴随疾病,正确手法复位治疗,联合Brandt-Daroff康复训练,11例治愈,随访1年无复发;2例无效;1例后半规管、1例水平半规管BPPV,至他院行半规管堵塞术手术治疗,术后效果好。 结论 难治性BPPV可能与头部外伤及突发性聋等疾病相关,首先需根据病因积极治疗伴随疾病,同时采用正确的手法复位治疗,并联合康复训练。治疗后大部分患者疗效好,无效者行半规管堵塞术效果好。     

190例特发性良性阵发性位置性眩晕患者半规管功能分析

目的 分析特发性良性阵发性位置性眩晕(benign paroxysmal position vertigo,BPPV)患者半规管功能的特征,为患者的治疗提供进一步帮助.方法 选择本院2019年8月至2020年2月收治的单侧特发性BPPV患者190例,包括后半规管BPPV患者162例,水平半规管BPPV患者28例.行冷热...     

Effectiveness of treatments for benign paroxysmal positional vertigo of the posterior canal.

OBJECTIVE: To determine which common, nonpharmacological, nonsurgical treatments are most effective for treatment of benign paroxysmal positional vertigo (BPPV). STUDY DESIGN: Prospective, randomized, sham-controlled. PATIENTS: Patients (n = 124) with BPPV of the posterior semicircular canal. SETTING: Tertiary care center. INTERVENTIONS: Random assignment to one of five groups: modified canalith repositioning maneuver (CRP), modified liberatory maneuver (LM), sham maneuver, Brandt and Daroff's exercise, and vertigo habituation exercises. Subjects received a standard educational lecture about BPPV and the purpose of the intervention. No vestibular-suppressant medication or special instructions for head positioning were used. Post-tests were given at 1 week after treatment and at approximately 3 months and 6 months later. MAIN OUTCOME MEASURES: Vertigo intensity and frequency. RESULTS: Multilevel analyses showed that vertigo decreased significantly after LM, CRP, and Brandt-Daroff exercise; those three groups did not differ significantly. The habituation group did not differ from sham, Brandt-Daroff, LM, or CRP groups. Changes in scores were maintained throughout the 6-month follow-up period. CONCLUSION: LM, CRP, and exercises are all effective interventions; patient education plus the sham maneuver, however, had some beneficial effect. These results support two possible mechanisms of BPPV: displaced otoconia and a neural mechanism affecting interpretation of semicircular canal signals.     

前庭康复对老年良性阵发性位置性眩晕患者后遗头晕的疗效

目的 探讨前庭康复训练对老年良性阵发性位置性眩晕(BPPV)患者后遗头晕的疗效。 方法 选择BPPV患者耳石成功复位治疗眼震消失3 d仍后遗头晕患者86例,按照随机表法分为观察组43例与对照组43例。对照组采用甲磺酸倍他司汀治疗,观察组在对照组基础上结合前庭康复训练,两组疗程均为7 d。比较两组治疗疗效、治疗前后BBS评分、VSI评分及DHI量表评分。 结果 观察组总有效率(95.35%)高于对照组(72.09%)(P<0.05)。观察组治疗前BBS评分为7.39±1.24,治疗后为49.81±4.56;对照组治疗前BBS评分为7.61±1.27,治疗后为39.62±3.21,观察组治疗后高于对照组(P<0.05)。观察组治疗前VSI评分为32.78±2.41,治疗后为24.87±3.28;对照组治疗前VSI评分为32.54±2.39,治疗后为28.46±2.80,观察组治疗后低于对照组(P<0.05)。观察组治疗前DHI量表总分为76.44±6.57,治疗后为30.81±3.24;对照组治疗前DHI量表总分为76.36±5.82,治疗后为42.36±4.67,观察组治疗后低于对照组(P<0.05)。 结论 前庭康复训练对老年BPPV患者后遗头晕疗效显著。     

Efficacy of BPPV diagnosis and treatment system for benign paroxysmal positional vertigo

ObjectivesTo evaluate the efficacy of automatic benign paroxysmal positional vertigo (BPPV) diagnosis and treatment system for BPPV compared with the manual repositioning group.MethodsTwo hundred thirty patients diagnosed as idiopathic BPPV who were admitted from August 2018 to July 2019 in Zhejiang Hospital were included. Among them, 150 patients of posterior semicircular canal BPPV(pc-BPPV), 53 patients of horizontal semicircular canal BPPV(hc-BPPV), and 27 patients of horizontal semicircular canal calculus (hc-BPPV-cu) were randomly treated with BPPV diagnosis and treatment system(the experimental group) or manual repositioning (the control group). Resolution of vertigo and nystagmus on the Dix-Hallpike and Roll test on day 3,day 7,day 14 and day 28 follow-up after first treatment was the main outcome measure to assess the efficacy of treatment.ResultsAt 3-day and 7-day follow-up after treatment with BPPV diagnosis and treatment system, 79%, 91%had complete resolution of vertigo and nystagmus, the effective rate in the experimental group were significantly higher than those in the control group, the differences were statistically significant(P < .05). On day 14, the effective rate in the experimental group (96%) was slightly higher than that in the control group(91%), but there was no significant difference between the two groups. And at 28-day after the first treatment, the effective rate was 100% in the experimental group and the control group. The repositioning efficiency of pc-BPPV (the first, second, third treatment), hc-BPPV (the first, second, third treatment), hc-BPPV-cu(the first, second treatment) in the experimental group were higher than the control group, and the secondary reposition of pc-BPPV in the experimental group was significantly higher than the control group(96%vs.84%; P < .05). While for the hc-BPPV-cu patients, the effective rate of the third treatment in the experimental group was slightly lower than that of the control group, but the differences were not statistically significant.ConclusionsBPPV diagnosis and treatment system is effective for the treatment of BPPV, with a better effective rate than those treated with manual maneuver, and is safe and easy to perform on patients.     

原发性良性阵发性位置性眩晕患者VEMP异常率的临床观察

目的 比较原发性初发和复发良性阵发性位置性眩晕(BPPV)患者的前庭诱发肌源性电位(VEMPs)特点,探索原发性BPPV屡次复发的可能发病机制。 方法 收集首次就诊即确诊为单侧原发性BPPV的患者57例,其中初发患者36例,复发患者21例。所有患者均进行气导声刺激条件下的颈肌VEMP(cVEMP)和眼肌VEMP(oVEMP)检查,对比分析初发组和复发组cVEMP和oVEMP结果的差异。 结果 (1)初发和复发BPPV组在性别、发病侧别及受累半规管均无统计学差异(P>0.05),年龄存在统计学差异(P<0.05);(2)57例BPPV患者中21例(36.84%)cVEMP异常,35例(61.40%)oVEMP异常,oVEMP异常率更高(P<0.05);分别对初发组中和复发组中的cVEMP和oVEMP异常率进行比较,结果显示两组oVEMP异常率更高,差异具有统计学意义(P<0.05);(3)初发BPPV组cVEMP异常有16例(44.45%),复发BPPV组异常有5例(23.81%);初发BPPV组oVEM异常有19例(52.79%),复发BPPV组中oVEMP异常有16例(76.19%);两组cVEMP和oVEMP异常率均无统计学差异(P>0.05);(4)复发2次组和复发3次以上组,与初发组进行VEMPs异常率比较显示三组间cVEMP及oVEMP异常率均无统计学差异(P>0.05)。 结论 原发性初发组和复发组BPPV患者的cVEMP和oVEMP异常率差异均无统计学意义,提示耳石器功能异常可能不是原发性BPPV患者反复复发的发病机制。     

探究参苓白术散加味治疗儿童变应性鼻炎的临床价值

目的探究在儿童变应性鼻炎中应用参苓白术散加味治疗的临床价值。方法择取120例罹患变应性鼻炎的患儿,均为我院2016年5月至2020年7月期间收治,随机分组,即对照组(常规西医)与观察组(联用参苓白术散加味)各60例总有效率评定结果、中医证候积分测评分值及复发率情况加以对比。结果相较对照组,观察组有更高的治疗有效率(P<0.05);观察组症状积分经评测相较对照组居更低水平(P<0.05);安排在3个月时复查,相较对照组,观察组复发率居更低水平(P<0.05)。结论针对罹患变应性鼻炎的患儿,取参苓白术散加味方案应用,可促使患儿症状得以有效改善,复发率明显降低,总体效果理想。     

FESS术后加用香菊胶囊与康复新液治疗慢性鼻窦炎伴有鼻息肉的对比研究

目的 评价对比慢性鼻窦炎伴有鼻息肉患者功能性鼻内镜手术后,分别加用香菊胶囊口服治疗与康复新液冲洗术腔治疗的有效性及安全性.方法 选取择期行FESS治疗的90例CRSwNP患者,使用简单随机数字表法将其随机分成康复新组(n=30)、香菊组(n=30)、对照组(n=30).所有患者均接受FESS及相同的术后常规处理.对照组...     

Benign Paroxysmal Positional Vertigo without nystagmus: diagnosis and treatment

Nystagmus tests to diagnose BPPV are still relevant in the clinical evaluation of BPPV. However, in everyday practice, there are cases of vertigo caused by head movements, which do not follow this sign in the Dix-Hallpike maneuver and the turn test.AimTo characterize BPPV without nystagmus and treatment for it.Materials and methodsA non-systematic review of diagnosis and treatment of benign paroxysmal positional vertigo (BPPV) without nystagmus in the PubMed, SciELO, Cochrane, BIREME, LILACS and MEDLINE databases in the years between 2001 and 2009.ResultsWe found nine papers dealing with BPPV without nystagmus, whose diagnoses were based solely on clinical history and physical examination. The treatment of BPPV without nystagmus was made by Epley maneuvers, Sémont, modified releasing for posterior semicircular canal and Brandt-Daroff exercises.ConclusionFrom 50% to 97.1% of the patients with BPPV without nystagmus had symptom remission, while patients with BPPV with nystagmus with symptom remission ranged from 76% to 100%. These differences may not be significant, which points to the need for more studies on BPPV without nystagmus.