包皮环切术切口缝合方法改进的体会

目的 介绍一种包皮环切后切口缝合的方法,以减轻拆线时患者的痛苦.方法 凡士林油纱条上缝线的交叉打结法,切口愈合后只需剪断油纱条上面的结扎线即可顺利拆除切口缝线.结果 150例患者顺利拆除切口缝线,拆线时较传统缝合方法明显减轻了患者疼痛,且拆线所需时间缩短,切口愈合良好.结论 包皮环切术切口缝合法对减轻拆线时患者的痛苦及医务人员的工作量效果明显,值得临床推广.     

包皮环切术切口缝合的改进

目的：绍一种改进的包皮环切后切口缝合的方法，以减轻拆线时病人的痛苦和医务人员的工作量。方法：包皮环切后切口缝线先不结扎，提起切缘缝线两端，交叉拉紧，放置凡士林油纱条1根，在油纱上面打结，切口愈合后只需剪断油纱条上面的结扎线，即可顺利拆除切口缝线。结果：50例患者顺利拆除切口缝线，均无明显疼痛。拆线所需时间缩短，切口愈合良好。结论：改进的包皮环切术切口缝扎法，对减轻拆线时的患者的痛苦及医务人员的工作量效果明显，值得临床推广，     

包皮环切术缝合法的改进

1985年以来,我院在包皮环切术中对缝合法加以改进,共治疗36例,减轻病员拆线痛苦,效果良好,现介绍如下。行常规包皮环切后,用小三角针和1号缝合线,先在阴茎背侧及腹侧,缝针穿过内外板切口缘,各缝一针作牵引。在此线牵引下,再分别在2,4,8,10点针位各缝合一针,将每针两线头交叉(只交叉,不打结),在缝线交叉点面上压一条橡皮片引流条(可采用废乳胶手套剪成,浸于0.1％新洁尔灭溶液内消毒备用。皮片宽约0.5cm,长以     

介绍一种包皮环切术后不需拆纯的缝合法

传统的包皮环切术后拆线时 ,患者疼痛难以忍受 ,尤其是小儿患者。我院 2 0 0 1年 1月～ 2 0 0 2年 1月 ,采用无需术后拆线的缝合法 ,手术治疗包皮过长36例 ,效果满意 ,现报告如下。1　临床资料1.1　一般资料　 36例患者中 ,包茎 2 0例 ,包皮过长 16例 ;年龄 6～ 39岁 ,平均 (2 3± 2 )岁。1.2　手术方法　行常规消毒 ,阴茎根部局麻 ,切除过长包皮 ,结扎活动性出血点。缝合时 ,使用 1 0或2 0号无创伤丝线距皮缘约 1ｍｍ缝合包皮内外壁 ,缝合线交叉 1次 ,不打结 ,在交叉点上放置油纱条 ,同时将结打于油纱条上 ,依次缝合。1.3　结果　术后 5～…     

三种包皮环切术治疗包茎及包皮过长的方法与疗效比较

目的探讨包皮环切的理想术式。方法对548例包茎、包皮过长患者随机分为改良包皮环切术（A组）230例、袖套式包皮环切术（B组）112例、传统背侧切开包皮环切术（C组）206例，对三组术中出血量、手术时间及术后创口出血、血肿、水肿、疼痛、感染、粘连、外观差等并发症进行观察，并进行随访，比较其治疗效果。结果A组术中出血量为（5．3±2．1）mL，B组为（10．2±3．2）mL，C组为（8．3±3．6）mL（P〈0．001）；手术时间分别为（25±7）min、（58±15）min、（31±8）min（P〈0．001）；并发症发生率分别为7．0％、8．9％和12．6％（P〈0．001）。结论改良包皮环切术比传统的包皮环切术及袖套式包皮环切术更具有优越性，其操作简单，耗时短，并发症少，值得推广。     

免拆线缝合法在包皮环切术中的应用

0　引言　传统的包皮环切术方法是需要拆线的 ,尤其不配合的小儿甚至要在全麻下拆线 ,这是十分麻烦的 .免拆线缝合法包皮环切术实现了既缝合了切口又避免了拆线 ,同时简化了手术过程 ,易学、易懂 ,便于推广 .1　对象和方法　 1990 - 0 1/ 2 0 0 0 - 12 ,6 2 7例全部采用了免拆线缝合法 .年龄 2～ 72 (平均 19.6 )岁 .包茎 6 5例 ,包皮过长 5 6 2例 .出现切口完全裂开的 1例 ,部分切口裂开的 2 6例 .切口全部感染的 2例 ,切口部分感染的 9例 .术后继发出血 8例 .愈后无疤痕过大及系带过短者 .术中包皮环切的过程与传统的手术方法无异 ,电刀电…     

内外板分别环切及交叉压条缝合法进行包皮环切术156例报告

2000年以来，采用内外板分别环切及交叉压条缝合法进行包皮环切术治疗包皮过长患者156例，取得了满意疗效，现报告如下。     

一次性包皮切割缝合器与两种传统包皮环切术的应用比较

目的 比较一次性包皮切割缝合器与传统包皮环切术和套扎环包皮环切术的临床应用效果.方法 对我院2016年7月-2016年12月内门诊收治的包皮过长和包茎患者,采用不同手术方法治疗,其手术时间、术中疼痛评分(VAS评分)、术后水肿、疼痛持续时间、以及外观满意度等方面进行对比.结果 在手术时间和外观满意度方面一次性包皮切割缝合器明显优于传统包皮环切术;在术中疼痛评分(VAS评分)、疼痛持续时间和术后水肿方面一次性包皮切割缝合器明显优于套扎环包皮环切术.结论 一次性包皮切割缝合器与两种传统常规手术比较,手术更加简单、方便且安全,术后外观满意度高,值得临床推广.     

比较采用一次性包皮环切缝合器与袖套式包皮环切术的临床疗效

目的研究实行一次性包皮环切缝合器与袖套式包皮环切术的临床疗效比较。方法两组患者将分别接受一次性包皮环切缝合器和袖套式包皮环切术治疗。观察比较两组患者术前、术中、术后的情况。结果对照组和试验组的手术时间分别为(11.83±1.93)min和(30.23±2.91)min;患者的术中出血量分别为(7.83±1.94)m L和(1.13±0.91)m L;患者术中疼痛率分别为73%、24%;患者术后切口愈合时间分别是(14.83±1.54)d和(14.01±1.04)d;患者术后外观的满意率分别为53%、91.2%。结论采用一次性包皮环切缝合器对包皮、包径过长患者具有重要的临床价值,值得临床推广使用。     

血管分离保全法激光包皮环切122例

目的 评价血管分离保全法CO2激光包皮环切术的治疗效果. 方法 对A组122例包皮过长患者,中包茎8例,皮嵌顿3例,皮囊肿2例,锐湿疣23例,行血管分离保全法CO 2激光包皮环切,期B组114例包皮过长患者,中包茎6例,皮嵌顿2例,皮囊肿1例,锐湿疣19例,行常规的CO 2激光包皮环切,两组手术时间、术中出血量、愈合拆线时间以及水肿、血肿、伤口感染等并发症进行比较.结果 A组中手术时间37.45±2min,中出血量3.6±1ml.愈合拆线时间5±1d ,组手术时间25.30±1min,中出血量10.8±2ml ,合拆线时间7±2d,比差异有统计学意义(P <0.01);A组水肿3例(2.5%),肿1例(0.8%),口感染1例(0.8 %),组水肿13例(11.4%),肿6例(5.3%),口感染4例(3.5 %),组并发症发生率对比差异有显著性意义(P <0.05).结论 血管分离保全法CO2激光包皮环切可减少术中出血、降低并发症发生率,合加快,效满意.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.