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【摘要】目的:探讨新型冠状病毒肺炎(COVID-19)报告与数据系统(CO-RADS)评分及临床特征诊断COVID-19的价值。方法:回顾性分析本院COVID-19疫情期间就诊的169例患者的临床及影像资料,其中男68例,女101例,年龄15~98岁,平均(58.0±15.5)岁,入院后均行胸部CT、核酸及抗体检测。由两位影像医师独立进行CO-RADS评分,评价结果一致性,最终评分结果由两者协商确定。以核酸及抗体结果为金标准,分析CO-RADS评分的诊断效能,采用二元logistics回归分析评分预测COVID-19发生的风险。结果:169例患者中共139例确诊为COVID-19,临床症状以发热、咳嗽较常见(59.7%,51.8%),COVID-19患者CRP升高(χ2=15.93,P=0.000)及淋巴细胞百分比降低(χ2=4.11,P=0.043)较非COVID-19患者发生率高。COVID-19患者CT主要表现为病变多发(115/139,82.7%),下叶受累常见(102/139,73.4%),多位于外周或胸膜下(125/139,89.9%),磨玻璃密度(109/139,78.4%)伴铺路石征(83/139,59.7%)是特征表现之一。两位医生对169例患者CO-RADS评分具有较好一致性,线性加权Kappa分析系数值为0.84(95%CI:0.78~0.89)。COVID-19患者评分较非COVID-19患者高(Z=-7.473,P=0.000)。CO-RADS评分诊断COVID-19的ROC曲线下面积(AUC)为0.91(95% CI :0.85~0.95,Z=13.71,P<0.0001),最佳截断值为3,其敏感度、特异度分别为88.5%、83.3%。单因素二元logistics回归分析显示CO-RADS评分是诊断COVID-19的危险因素,评分为2~5分时其风险是1分的3.43、4.67、45.00、312.00倍。结论:不同医师的CO-RADS评分一致性好,诊断效能高,评分越高COVID-19的风险越大。 相似文献
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新型冠状病毒肺炎(COVID-19)被发现以来,迅速蔓延,其早期诊断有利于患者的及时救治和疾病进一步传播的有效控制。目前,诊断的依据是流行病史、临床表现、影像学特征和逆转录聚合酶链式反应(RT-PCR)检测结果,其中RT-PCR检测到新型冠状病毒核酸阳性是COVID-19确诊的主要依据,影像学特征尤其是肺部高分辨率CT表现则是诊断该病的重要临床依据。作为一种被广泛应用的影像学方法,18F-FDG PET/CT在COVID-19中的价值仍未可知。笔者分析了18F-FDG PET/CT在COVID-19中的诊断和鉴别诊断的价值,以及评估COVID-19患者纵隔淋巴结受累情况方面的潜在应用,讨论了COVID-19患者肺外器官和组织受累可能出现的18F-FDG PET/CT影像学表现。 相似文献
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【摘要】目的:探讨薄层高分辨率肺部CT在新型冠状病毒肺炎(COVID-19)中的诊断价值。方法:回顾性分析2020年1月20日-2020年2月10日本院发热门诊收治的120例患者的CT图像、临床和实验室资料(白细胞计数,淋巴细胞计数,淋巴细胞百分数,C反应蛋白及SARS-CoV-2核酸检测结果),计算CT诊断新冠肺炎的敏感度、特异度、阳性和阴性预测值。结果:120例中男49例,女71例,年龄(50.7±17.1)岁;白细胞计数正常及减低者110例(91.7%);淋巴细胞百分数正常及减低者 118例(98.3%);淋巴细胞计数正常及减低者120例(100%);C反应蛋白升高者67例(55.8%)。本组中最终确诊COVID-19患者91例,首次SARS-CoV-2核酸检测阳性81例,检出率为89.0%。120例患者中首次CT筛查诊断为新型冠状病毒肺炎104例,诊断敏感度、特异度、阳性和阴性预测值分别为96.7%、44.8%、84.6%和81.3%。结论:高分辨率薄层肺部CT检查能及时、敏感地检出病毒性肺炎,弥补部分新型冠状病毒肺炎患者首次核酸检测阴性的不足,使临床医师能及早对临床疑似病例采取隔离等处置措施,阻止疫情进一步扩散。 相似文献
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【摘要】目的:总结核酸检测阴性新型冠状病毒肺炎(COVID-2019)的CT表现特点,提高对该病早期病变的认识。方法:从3次核酸检测最终确诊为COVID-2019的 217例患者中,选取之前核酸检测阴性的56例患者为研究对象,回顾性分析其胸部CT表现。结果:56例核酸检测阴性患者中,首次胸部CT有2例(3.57%)未见异常,54例(96.43%)可见异常。54例胸部CT有异常患者的病变分布特点:累及单肺叶12例(22.22%),其中病变位于左下叶6例;累及多肺叶42例(77.78%),其中37例累及3~5个肺叶。病灶形态:表现为类圆形15例(27.78%),楔形9例(16.67%),不规则形30例(55.56%)。病变密度:表现为磨玻璃影(GGO)36例(66.67%),GGO+实变13例(24.07%),以实变为主5例(9.26%)。间质性改变:小叶核心间隔增厚(铺路石征)28例(51.85%),小叶间隔增厚16例(29.63%),细支气管充气征25例(46.30%)。CT分期情况:早期26例(48.15%),进展期23例(42.59%),重症期4例(7.41%),转归期1例(1.85%)。结论:96.43%的核酸检测阴性COVID-2019患者首次胸部CT可见阳性表现,CT分期主要为早期(48.15%)和进展期(42.59%),重症少见(7.41%),对胸部CT出现阳性表现即使核酸检测阴性者需高度重视,及时复查。 相似文献
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目的探讨新型冠状病毒肺炎(COVID-19)CT表现及定量CT肺功能对COVID-19肺功能评估。方法回顾性分析31例经病毒核酸检测确诊、且具有完整动态胸部HRCT资料的COVID-19患者,复查间隔时间48 h~14天。分析HRCT基本表现及CT-肺功能成像与临床分型的关系。结果31例患者均于发病3天内接受HRCT检查,病变检出率为100%。于发病5~7天复查CT,25例病变范围增大,3例病灶范围缩小,3例病灶范围同前;发病10~14天接受第2次复查,26例病变范围缩小,3例病灶范围增大;临床分型与CT肺功能值(PI)(r=-0.835,P<0.001)呈显著负相关。结论胸部HRCT能清晰显示COVID-19疾病影像学变化,CT肺功能与COVID-19相关,有助于指导临床早诊断、早治疗,并可评价COVID-19的临床治疗效果。 相似文献
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Miller E Metser U Avrahami G Dvir R Valdman D Sira LB Sayar D Burstein Y Toren A Yaniv I Even-Sapir E 《Journal of computer assisted tomography》2006,30(4):689-694
OBJECTIVE: To assess the role of 18F-Fluorodeoxyglucose (18F-FDG) PET/CT in pediatric patients with Hodgkin disease (HD) and non-Hodgkin lymphoma (NHL). MATERIALS AND METHODS: 31 patients, mean age 12.9 +/- 5.1, HD (n = 24), and NHL (n = 7) underwent 18F-FDG PET/CT at diagnosis (n = 31 studies) and later in the course of the disease (n = 75 studies). The findings of PET/CT were correlated with diagnostic CT and clinical follow-up. RESULTS: PET/CT findings resulted in a change of disease staging in 10 patients (32.3%), upstaging in 7 (22.6%) and downstaging in 3 (9.6%). On a lesion analysis, 164 disease sites were detected by PET/CT of which 38 were overlooked by DCT.At mid-treatment, PET was negative in 28 out of 31 patients (90%) with negative predictive value of 96% as all latter patients except for 1, were disease free (mean 15.4 +/- 8.8 months). The positive predictive value of persistent increased 18F-FDG uptake was 100% as 3 patients with latter findings had active disease. On the CT part, 76 residual masses were identified in 22 patients. Increased 18F-FDG uptake was detected in 11 masses in 4 patients who had active disease. Remaining 65 PET negative masses were false positive findings. The positive predictive value of residual CT mass was 14%. CONCLUSIONS: PET/CT is associated with change in staging in approximately 1 out of 3 pediatric patients with HD and NHL. When used for monitoring response to treatment, a negative study is associated with disease-free period, even when residual mass is detected. A positive PET study indicates residual malignant disease. 相似文献
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目的 探讨儿童新型冠状病毒肺炎(COVID-19)患者高分辨率CT(HRCT)表现。方法 回顾性分析2020年1月25日至2月5日华中科技大学同济医学院附属武汉儿童医院22例经临床及核酸检测确诊为COVID-19患儿的胸部HRCT表现。其中男12例,女10例,年龄2个月~14岁,中位年龄4岁,5岁以下患儿14例。由2名放射科医师共同观察肺部病变分布、形态、密度等特征及有无肺门、纵隔淋巴结肿大及胸膜改变。结果 22例患儿中,3例(3/22)肺部CT正常,19例(19/22)肺部HRCT见病灶浸润,其中单侧肺病变7例,双侧肺病变12例。HRCT表现为:磨玻璃影6例,其中淡磨玻璃影4例、典型铺路石征磨玻璃影2例;4例呈肺实变改变,表现为局限性条索影、斑片状高密度影;6例表现为实变影与磨玻璃影共存,呈斑片状致密影夹杂周围磨玻璃影改变,其中1例呈右侧白肺表现;3例呈类支气管肺炎改变,表现为肺叶内散在点状或斑片状密度不均高密度影。下叶病灶较上叶为重,肺外后带较肺尖部、中央区多见。全部患儿均未见肺门淋巴结增大和胸腔积液,1例见叶间胸膜增厚。结论 儿童COVID-19的HRCT表现多样化,需结合流行病学资料、临床表现及实验室检测综合判断,但肺部CT表现可作为临床早期诊断和防控干预的重要依据。 相似文献
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Rubinder Birk Dominick Shaw Cheika Kennedy Yutaro Higashi Roma Patel Ayushman Gupta Iain Au-Yong 《Current problems in diagnostic radiology》2021,50(5):656-661
PurposeCritically ill patients with coronavirus disease 2019 (COVID-19) are at increased risk of thrombosis. There are limited data on PE rates in COVID-19 patients at presentation to the emergency department (ED). In this study, we evaluated the detection rates of PE in patients presenting to the ED with suspected and proven COVID-19.MethodsA single-centre retrospective study was undertaken of 285 consecutive patients undergoing CT pulmonary angiogram (CTPA) in the Emergency Department at Nottingham University Hospitals NHS Trust in the United Kingdom between 25 March and 30 April 2020. At our institution, CTPA is performed in all patients undergoing CT for triage. The study group consisted of patients considered COVID-19 positive based on polymerase chain reaction (PCR) results and CTPA findings. The detection rate of PE in COVID-19 patients was compared to patients undergoing CTPA for suspected PE only and for suspected COVID-19 with no COVID CT findings and negative PCR (control group 1); and CTPAs prior to the coronavirus pandemic (control group 2).ResultsOne of 48 patients in the study group had a PE (2%) compared to 25/215 (12%) in control group 1 and 10/50 (20%) in control group 2. Prevalence of PE in the study group was lower than in control group 1 (P = 0.058) and compared to control group 2 (P = 0.005). Eleven patients undergoing CTPA had negative PCR but positive CT for COVID-19.ConclusionDetection rate of pulmonary embolus is low in patients with COVID-19 undergoing CTPA on a triage pathway. 相似文献