女性流浪精神障碍患者非正常性行为调查分析及对照研究

目的:探讨女性流浪精神障碍患者的非正常性行为的临床特点。方法:对2005-2010年由南京市社会救助站送入我院的女性流浪精神障碍患者的非正常性行为进行调查分析及对照研究。结果:女性流浪精神障碍患者非正常性行为发生率显著高于男性流浪患者及常规入院女性患者,有低龄化及高龄化趋势,性病发生率高,情感性精神障碍及精神发育迟滞患者非正常性行为发生率高。结论:女性流浪精神障碍患者极易受到性侵犯,已成为性病感染高危人群,在其救助过程中要做好性病筛查,性安全知识教育,同时需要公安、民政救助、卫生医疗、社区等机构多方协作,共同维护女性流浪精神障碍患者的权益。     

流浪精神障碍患者的临床特点与治疗方式研究

目的 探讨流浪精神障碍患者的临床特点及其治疗方法.方法 选取我院2014年1月—2015年12月收治的流浪精神障碍患者148例进行研究,总结其临床特点,分析治疗方法及疗效.结果 148例流浪精神障碍患者中男性显著多于女性,年龄以25岁~50岁最多,入院原因以乞讨流浪为主,其次有言语行为怪异、伤人毁物等;入院诊断显示精神分裂症最多,其次为精神病性障碍、精神发育迟滞、器质性精神障碍等.经过临床药物治疗与康复训练,住院时间2 d~78 d,平均(8.6±1.3)d,最终救助站遣返原籍最多,其次为家属接出院,剩余无法查清身源或找不到家属,病情稳定后送至福利院管理,住院期间无1例死亡.结论 流浪精神障碍患者比较常见,男性显著多于女性,且以成年人为主.政府需加大对流浪精神障碍患者的关注力度,建立相应的福利院或收容点,及时制定政策与措施提供帮助.     

1749例流浪精神病患者的临床分析

目的:分析在城市流浪精神病患者的临床特征。方法:回顾性分析东莞市新涌医院2007年1月至2010年12月收治的1749名流浪精神病患者的临床特征。结果:住院的流浪精神病患者中以男性、广东省外的青年为主,大多为精神分裂症患者,部分既往有精神障碍史,67%合并有躯体疾病,病情稳定后大部分为家人接领或救助出院。结论:流浪精神病患者的救治工作复杂,与社会安全、和谐幸福息息相关,须高度重视并积极解决存在问题。     

流浪与正常住院精神障碍患者常见抗原抗体检测结果对照研究

目的:了解流浪乞讨精神障碍患者常见抗原抗体阳性携带情况。方法:对2005年10月至2009年9月在南京市青龙山精神病院住院的流浪精神障碍患者701例采用金标记免疫分析技术(胶体金法)检测乙肝五项、抗HIV、抗Tp抗体;采用ELISA法检测抗HAV、抗HCV抗体,同期正常住院的460例精神病患者为对照组,并对检测结果进行统计学分析。结果:701例流浪精神障碍患者抗Tp抗体阳性率4.1%(其中男性2.2%,女性6.2%,女性显著高于男性,P<0.01),HBV总感染率45.4%,抗-HBs阳性率31.8%,显著高于对照组(P<0.01);HBsAg阳性率9.3%,抗-HBc阳性率19.0%,高于对照组(P<0.05);抗-HCV阳性率2.4%,HBeAg阳性率1.9%,抗-HBe阳性率5.8%,两组间差异无显著性(P>0.05);流浪精神障碍患者发现1例抗-HAV阳性和1例抗-HIV阳性。结论:流浪乞讨精神障碍患者是某些传染病感染的高危人群,女性流浪精神障碍患者是梅毒感染的高危人群,应该常规血清标志物检查,加强监管,积极预防和治疗。     

男性流浪精神障碍患者的临床特点及治疗分析

目的：探讨男性流浪精神障碍患者的临床特点及治疗方法。方法：对比分析男性流浪与非流浪精神障碍患者的临床特点及疗效。随机选择我院2007年1月至2008年9月收治的男性流浪精神障碍患者共40例作为观察组,以同期在本院首次住院的40例男性非流浪精神障碍患者作为对照组,评价两组患者入院时的精神症状、合并躯体病情况、精神疾病诊断及治疗8周后的总体疗效。结果：两组在年龄、来源、婚姻状况、受教育程度、PANSS评分、诊断、合并躯体病、疗效等方面均有显著性差异。结论：男性流浪精神障碍患者精神症状重,问题行为突出,躯体状况差,多缺乏主诉。治疗强调以精神药物治疗、认知行为治疗及躯体病防治并举的综合治疗。     

对流浪救助精神障碍患者的治疗与思考

目的总结流浪救助精神障碍患者的治疗措施,分析关于流浪救助精神障碍患者的管理工作,降低流浪救助精神障碍患者。方法对我院在2011年1月到2012年1月期间收治治疗的流浪救助精神障碍患者的临床资料进行回顾性分析。结果在流浪救助精神障碍患者中,女性比例明显高于男性,P0.05;1流浪人口多数为外地户籍,对患者进行诊断(多数为精神分裂症)以及初步治疗后,大部分患者可找到家庭,但是个别患者由于病情较重或者无名等情况无法找到家庭。最终多数患者均由当地救助站送回家中,少部分家属主动接回患者,个别患者由于其他原因滞留在院。结论流浪救助精神障碍患者需要家庭以及社会的关爱,需要进一步的发挥家庭作用。     

流浪救助精神障碍者临床特征分析

目的:分析我院收治的流浪救助精神障碍者一般情况、诊断、治疗及回归社会等存在的问题,提出对策.方法:采用自行设计调查表,调查272例流浪救助精神障碍者,将数据进行统计学处理.结果:患者中男性多于女性,以外地和户口地址不详为主,其来源有显著差异(P＜0.05).入院原因以危害社会治安、伤人及破坏行为最多(66.90%).结论:以精神分裂症最多,滞留医院者最多;民族的构成呈汉>维>回>哈>蒙.     

流浪精神病患者的智力特点及影响因素分析

目的探讨流浪精神病患者的智力特点及影响因素,为临床提供一定借鉴。方法回顾性分析本院在2015年4月~2017年4月间从各地救助站接收的60例流浪精神病患者的病历资料,所有患者均经韦氏成人智力测验测定智力符合精神障碍诊断与DSM-Ⅳ诊断标准。统计分析本组60例患者的首次流浪年龄、流浪时间、性别以及文化程度等资料,并采用SPSS 20.0进行统计分析。结果本组60例患者中,男性的总智商评分为(66.82±17.91)分,明显高于女性的(61.84±12.98)分,组间差异显著(P0.05)。流浪精神病患者的智力与其受教育水平、首次流浪年龄呈现出较明显的正相关,与被救助次数以及流浪时间呈现出较明显的负相关。结论对于流浪精神病患者来说,因其具备一定的特殊性,所以社会相关部门还应针对这一群体积极采取有效的措施,如建立特殊教育学校以及建立患者档案等,帮助患者减轻心理压力,改善生活质量,减少家庭负担。     

流浪精神病患者130例临床分析

目的:了解流浪精神病患者精神障碍临床特征.方法:对我院收治的130例住流浪精神病患者进行调查.结果:精神障碍以精神分裂症居首位,待分类的精神障碍、精神发育迟滞多见,且伴有明显的行为异常,往往合併有躯体疾病,病情较为复杂.讨论:对流浪精神病患者需充分认识并采取综合措施救治.     

对101例流浪救助精神障碍患者的治疗与思考

目的：通过对我院101例流浪救助精神障碍患者的治疗与思考,探索依法加强流浪救助精神障碍患者的管理,减少流浪救助精神障碍患者的措施.方法：采用自编调查表,对我院2008年1月1日至2012年12月31日5年收治的流浪救助精神障碍患者病例资料进行回顾性调查分析与思考.结果：流浪救助精神障碍患者女性比例略高于男性,户籍大多为本地户口,经过诊断后的初步治疗,多数找到家庭,由于病情原因,无名或不详占有一定比例,诊断大多为精神分裂症.出院方式以救助站送回居多,家属主动接回占有一定比例,部分滞留在院.结论：我院流浪救助精神障碍患者家庭重视、关怀、关注尚需加强,家庭应有作用有待进一步发挥.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.