Are nasal spectacles adequate for supplementary oxygen in patients after anaesthesia?

Two methods of oxygen delivery were compared when used postoperatively after a general anaesthetic had been administered. There were 255 patients randomly allocated to receive oxygen via nasal spectacles or a Hudson face mask in the initial postoperative period. Oxygen saturation was monitored using pulse oximetry. Seven percent of patients who received the Hudson mask and 14% of patients who received nasal spectacles desaturated below 94% (P = 0.10). Age, weight or American Society of Anesthesiologists (ASA) status did not predict oxygen desaturation; however, desaturation occurred more frequently in male patients with nasal spectacles undergoing abdominal surgery. If male patients who had abdominal surgery with muscle relaxants are excluded from the nasal spectacle group, the desaturation incidences for spectacles and masks are similar (10% versus 7%, P = 0.38). Using nasal spectacles for all postoperative oxygen therapy in selected patients is therefore feasible and could provide substantial cost-saving.     

Prospective,randomized comparison of two supplemental oxygen methods during gastroscopy with propofol mono-sedation in obese patients

BACKGROUNDHypoxemia is a common complication in obese patients during gastroscopy with sedation. The Wei nasal jet tube (WNJT) is a new special nasopharyngeal airway with the ability to provide supraglottic jet ventilation and oxygen insufflation via its built-in wall channels. The aim of this study was to compare the efficacy and safety of the WNJT vs a nasal cannula for supplemental oxygen during gastroscopy with propofol mono-sedation in obese patients.AIMTo compare the efficacy and safety of the WNJT vs a nasal cannula for supplemental oxygen during gastroscopy with propofol mono-sedation in obese patients.METHODSA total of 103 obese patients with a body mass index of 30 kg/m² or more undergoing elective gastroscopy under propofol mono-sedation were randomly assigned to receive supplemental oxygen at 5 L/min through either a WNJT (WNJT group, n = 51) or a nasal cannula (nasal cannula group, n = 52). The lowest pulse oxygen saturation (SpO₂) and mild and severe hypoxemia during gastroscopy were recorded. The primary outcome was the incidence of hypoxemia.RESULTSThe lowest SpO₂ during gastroscopy with propofol mono-sedation was significantly increased in the WNJT group compared with the nasal cannula group. The incidence of mild hypoxemia and total incidence of hypoxemia were significantly lower in the WNJT group than in the nasal cannula group. Other than a higher incidence of epistaxis in the WNJT group, the occurrence of adverse events was similar between the devices. While neither device demonstrated a statistically significant difference in satisfaction among patients, the WNJT did result in improved satisfaction among anesthetists and physicians.CONCLUSIONDuring gastroscopy with propofol mono-sedation in obese patients, the WNJT, when compared with a nasal cannula for supplemental oxygen, can significantly reduce the occurrence of hypoxemia and improve both arterial oxygenation and satisfaction among anesthetists and physicians. The use of the WNJT may, however, lead to epistaxis in a few patients. In view of this clinically acceptable risk-benefit ratio, the WNJT may be recommended as an alternative tool for supplemental oxygen for the prevention of hypoxemia during gastroscopy with propofol mono-sedation in obese patients.     

鼻塞联合高氧液给氧预防高龄患者硬膜外麻醉低氧血症的研究

目的探讨鼻塞联合高氧液预防高龄患者硬膜外麻醉低氧血症的疗效。方法60例硬膜外麻醉的高龄患者,随机分为两组,每组30例。实验组为鼻塞联合高氧液给氧;对照组为单纯鼻塞给氧。观察两组患者麻醉前后不同时点PaO2、SpO2的变化。结果麻醉前两组间比较差异无显著意义;麻醉后各时点两组比较,实验组PaO2,SpO2明显高于对照组(P<0.01/P<0.05)。结论鼻塞联合高氧液给氧技术,能有效预防高龄患者硬膜外麻醉引起低氧血症的发生。     

早期氧气面罩雾化给氧对纠正重型颅脑损伤患者低氧血症的影响效果观察

目的探讨氧气面罩雾化给氧方式对重型颅脑损伤患者低氧血症的可行性及安全性,以促进患者早日康复。方法将收治98例重型颅脑损伤患者随机分为观察组48例和对照组50例,在常规治疗的同时,观察组采用氧气面罩接雾化器给氧方式进行给氧;对照组采用鼻塞导管湿纱布覆盖口鼻进行给氧。结果观察组其动脉血氧饱和度、氧分压明显提高。2组病死率比较差异明显,而2组患者的心率、血压、pH、PaCO2比较差异不明显。结论氧气面罩雾化器给氧能快速、有效纠正重型颅脑损伤患者缺氧状态,纠正低氧血症。     

早期氧气面罩雾化给氧对纠正重型颅脑损伤患者低氧血症的影响效果观察

目的 探讨氧气面罩雾化给氧方式对重型颅脑损伤患者低氧血症的可行性及安全性,以促进患者早日康复.方法 将收治98例重型颅脑损伤患者随机分为观察组48例和对照组50例,在常规治疗的同时,观察组采用氧气面罩接雾化器给氧方式进行给氧;对照组采用鼻塞导管湿纱布覆盖口鼻进行给氧.结果 观察组其动脉血氧饱和度、氧分压明显提高.2组病死率比较差异明显,而2组患者的心率、血压、pH、PaCO2比较差异不明显.结论 氧气面罩雾化器给氧能快速、有效纠正重型颅脑损伤患者缺氧状态,纠正低氧血症.     

不同给氧方法在脑肿瘤术后气管切开患者氧疗中的应用

目的探讨脑肿瘤术后气管切开患者氧疗中实施不同给氧方法的效果。方法选取脑肿瘤术后气管切开患者60例,按照随机数字法分为鼻导管组、人工鼻组、面罩组各20例,分别实施鼻导管吸氧、人工鼻吸氧及面罩法吸氧。观察3组患者氧疗前、氧疗1 h、氧疗24 h时的血氧饱和度、痰液黏稠度(Ⅲ度)以及并发症(肺部感染与切口感染)发生情况并进行统计学分析。结果 3组患者在吸氧1 h、吸氧24 h时的血氧饱和度均比吸氧前有显著提高(P0.05),但面罩组提高幅度显著更高(P0.05);鼻导管组与面罩组吸氧1 h、吸氧24 h时的痰液黏稠(Ⅲ度)率相比吸氧前显著下降(P0.05),优于人工鼻组(P0.05);面罩组与人工鼻组的肺部感染与切口处感染发生率差异无统计学意义(P0.05),均显著低于鼻导管组(P0.05)。结论面罩吸氧应用在脑肿瘤术后气管切开患者中有良好效果,不仅可快速平稳改善血氧饱和度,而且能降低痰液黏稠度以及肺部感染与切口感染的发生率,值得借鉴。     

Evaluation of Aromatherapy in Treating Postoperative Pain: Pilot Study

Abstract:   This study compared the analgesic efficacy of postoperative lavender oil aromatherapy in 50 patients undergoing breast biopsy surgery. Twenty-five patients received supplemental oxygen through a face mask with two drops of 2% lavender oil postoperatively. The remainder of the patients received supplemental oxygen through a face mask with no lavender oil. Outcome variables included pain scores (a numeric rating scale from 0 to 10) at 5, 30, and 60 minutes postoperatively, narcotic requirements in the postanesthesia care unit (PACU), patient satisfaction with pain control, as well as time to discharge from the PACU. There were no significant differences in narcotic requirements and recovery room discharge times between the two groups. Postoperative lavender oil aromatherapy did not significantly affect pain scores. However, patients in the lavender group reported a higher satisfaction rate with pain control than patients in the control group ( P  = 0.0001).     

无痛支气管镜检查中使用内镜面罩和鼻塞吸氧预防低氧血症发生的比较分析

目的观察内镜面罩和鼻塞两种不同的吸氧方法,对比二者在预防无痛支气管镜检查时引起的低氧血症的发生效果。方法选择行纤维支气管镜检查的患者131例,随机分为两组,A组63例,B组68例。A组用鼻塞法持续吸氧（5 L/min）,B组用内镜面罩持续吸氧。两组均采用芬太尼联合异丙酚静脉麻醉行无痛支气管镜检查,观察患者镜检前、中、后的脉搏氧饱和度（SpO2）、血压（BP）、心率（HR）以及术中和术后受检者的不适反应。结果①术中低氧血症发生率A组为36.5%,B组为7.3%,两组之间比较差异有统计学意义（P〈0.05）;②B组术中BP变化与术前比较,差异无统计学意义（P〉0.05）;A组术中BP下降与术前比较下降明显（P〈0.05）;③两组受检者术后SpO2、BP、HR与术前比较,差异无统计学意义（均P〉0.05）。结论芬太尼联合异丙酚静脉麻醉行无痛支气管镜检查,具有安全、无痛、不适反应少等特点。但在芬太尼和异丙酚静脉麻醉下采用鼻塞法吸氧进行纤维支气管镜检查时低氧血症发生率较高,内镜面罩吸氧法可有效降低低氧血症的发生,并且内镜面罩吸氧法行无痛支气管镜检查具有稳定血流动力学的效果。     

Cardiopulmonary complications during gastroscopy in patients with chronic respiratory failure undergoing long-term home oxygen therapy

BACKGROUND AND STUDY AIMS: Gastric ulcer and hemorrhage are major complications in patients with chronic respiratory failure, but upper GI endoscopy tends to be avoided because of possible cardiopulmonary events. This study was designed to evaluate hypoxemia and subsequent cardiac complications during gastroscopic procedures in patients with chronic respiratory failure undergoing long-term home oxygen therapy (LHOT). PATIENTS AND METHODS: Gastroscopy was carried out in 10 patients undergoing LHOT and 10 age-matched control subjects without pulmonary diseases. Oxygen saturation and cardiac arrhythmias before and during gastroscopy were monitored. Patients were given 10 mg intramuscular scopolamine butylbromide and local anesthesia using 100-300 mg lidocaine gel 15 minutes before the procedure. Each patient continued to receive oxygen via a nasal cannula in the same dosage as their daily use. RESULTS: Decrease in oxygen saturation during endoscopic procedure was significantly greater in patients undergoing LHOT (from 95.9+/-0.9 to 93.4+/-1.7%) compared with control subjects (from 96.7+/-0.4 to 96.2+/-0.4%). There was a significant correlation between the degree of hypoxemia and the oxygen dosage required for their daily treatment in the patients (r = 0.727, P<0.02). CONCLUSIONS: These results indicate that the degree of respiratory failure influences the degree of decrease in oxygen saturation during gastroscopy. It is suggested that use of the nasal route for oxygen supply may be one of the major causes of the hypoxemia.     

Effects of Intravenous Small Dose Ketamine and Midazolam on Postoperative Pain Following Knee Arthroscopy

Background:   The aim of this randomized, double blind, controlled study was to assess the effect of intravenous coadministration of small dose midazolam with ketamine on postoperative pain and spinal block level.
Methods:   Sixty patients undergoing arthroscopic knee surgery under spinal anesthesia were randomized into three groups: Group I (saline control); group II (ketamine 0.15 mg/kg i.v.); and group III (ketamine 0.15 mg/kg +  midazolam 0.01 mg/kg i.v.). Sedation scores, visual analogue scores, time to first postoperative analgesic, total meperidine consumption, patient satisfaction, sensory and motor block levels, and two segments regression times were assessed.
Results:   Sedation scores were significantly lower in group I when compared with groups II and III at 1, 3, 5, and 10 minutes after administration of the spinal anesthetic ( P  = 0.001). Sensory block was significantly higher in group III ( P  = 0.001) in comparison with group II. Two segment regression time was significantly longer in group II than group I, whereas no difference was found between groups II and III. Total meperidine consumption was significantly higher in group I ( P  = 0,001). Patient satisfaction was significantly higher in group III compared with group I ( P  = 0.001), but no difference was found between groups II and III ( P  = 0.3).
Conclusion:   Ketamine improved the postoperative pain patient satisfaction, increased the maximal sensory level, and was associated with lower sedation scores in the first 15 minutes after administration. Group I was also associated with decreased total meperidine consumption and delayed the time to first recue analgesic administration. Coadministration of ketamine and midazolam did not provide any further benefit over ketamine alone.     

经鼻高流量氧疗在胃减容术后患者中的应用

目的探讨经鼻高流量氧疗（HFNC）可否改善肥胖症患者胃减容术后低氧血症，提升术后呼吸舒适度。 方法采用前瞻性随机对照研究，选择2019年10月到2020年9月于上海市第十人民医院接受胃减容术后转入急诊ICU的肥胖患者为研究对象，根据随机抛硬币法将患者分为高流量组（22例，经鼻高流量氧疗）与传统氧疗组（28例，传统氧疗）。比较2组间患者一般资料，包括性别、年龄、体质量指数（BMI）、是否合并有睡眠呼吸暂停综合征（OSAHS）等，记录入科0.5 h、2 h、24 h动脉血气分析相关指标，夜间（20∶00-次日08∶00）心率（HR）、血氧饱和度（SpO₂）、最低SpO₂、氧减次数、呼吸暂停低通气指数（AHI）及舒适度等相关临床指标。 结果（1）2组患者年龄、性别及BMI比较，差异无统计学意义（P＞0.05）。（2）组间比较，高流量组患者2 h的PO₂、氧合指数及入科24 h PO₂、氧合指数明显高于传统氧疗组，PCO₂低于传统氧疗组，差异有统计学意义（P＜0.05），其余各指标组间比较，差异均无统计学意义（P＞0.05）。组内比较，高流量组入科2 h及24 h的pH、PO₂、氧合指数明显高于入科0.5 h时，差异有统计学意义（P＜0.05）；传统氧疗组入科2 h的pH及24 h的pH、PO₂、氧合指数明显高于入科0.5 h时，差异有统计学意义（P＜0.05），其余各指标不同时点组内比较，差异均无统计学意义（P＞0.05）。（3）12 h夜间睡眠监测相关指标中，高流量组患者夜间SpO₂、最低SpO₂高于传统氧疗组，HR、氧减次数低于传统氧疗组，差异有统计学意义（P＜0.05），而2组间AHI比较，差异无统计学意义（P＞0.05）。（4）高流量组患者主观舒适度优于传统氧疗组，差异有统计学意义（P<0.05）。 结论HFNC可以有效降低胃减容术后患者出现低氧血症风险，提升患者可接受度及主观舒适感。     

The men and history behind the Venturi mask

The delivery of supplemental oxygen is a critical part in the management of patients presenting with acute hypoxemia. While a number of delivery options are available, one of easiest and least invasive is the simple facemask or “Venturi” mask. Worldwide, these types of masks have been used for over 50 years. Developed initially as simple oxygen-delivery system, the face mask has evolved, acquiring more complexity and efficacy by the application of physical principles in an attempt to provide maximal patient benefit. The original Venturi mask was created by the British physician Earl James Moran Campbell. It was named after the Italian physicist Giovanni Battista Venturi who described the principal of increased velocity of a gas resulting in lower pressures, Campbell incorporated Venturi's principle into the oxygen delivery facemask. By using this principle, precise oxygen delivery occurs, thus, representing the standard of supplemental oxygen facemasks today.     

An Improvised Oxygen Supply System for Pandemic and Disaster Use

Background:  Current disaster planning for pandemic influenza anticipates overwhelming numbers of patients in need of hospitalization. The anticipated use of extra, or "surge," beds is common in both hospital and community disaster response planning. In a pandemic of respiratory illness, supplemental oxygen will be a life-saving intervention. There are currently few options to provide these proposed surge beds with the necessary oxygen.
Objectives:  A method of providing an improvised oxygen delivery system for use in a disaster was developed and tested. This system was designed to use readily available commercial materials to assemble an oxygen delivery system.
Methods:  The study consisted of a laboratory design, assembly, and testing of an improvised oxygen system.
Results:  A liquid oxygen (LOX) Dewar container was used to supply oxygen systems built from inexpensive commercially available plastic tubing and fittings. The system will drive ventilators without significant pressure drop or ventilator malfunction. The final developed system will supply 30 patients with up to 6 L/min (l pm) oxygen each by nasal cannula from a single oxygen Dewar.
Conclusions:  An improvised system to deliver oxygen for patient beds or ventilator use can be easily assembled in the event of a disaster. This could be life-saving in the event of a pandemic of respiratory illness.     

Investigating the Effects of Protective Face Masks on the Respiratory Parameters of Children in the Postanesthesia Care Unit During the COVID-19 Pandemic

PurposeThe purpose of this study was to investigate the effect of protective face mask usage during the postoperative period on carbon dioxide retention in children during the COVID-19 pandemic.DesignThis study was designed as a prospective, randomized trial including 40 ASA I–II patients aged 3 to 10 years who were scheduled for elective surgery.MethodsPatients were randomly allocated to two groups. The first group (group 1) received O₂ treatment over the protective face mask. In the second group (group 2), the protective face mask was worn over the O₂ delivery system. Heart rate, oxygen saturation (SPO₂) level, end-tidal carbon dioxide (EtCO₂) level, and respiratory rate were measured using a patient monitor at 0, 5, 10, 15, 30, and 45 minutes and recorded. The primary outcome of the study was the determination of the EtCO₂ levels, which were used to assess the safety of the mask in terms of potential carbon dioxide retention.FindingsNone of the participants’ SPO₂ levels fell below 92% while wearing masks. There was no statistically significant difference between the groups in terms of EtCO₂, heart rate, SPO₂, and respiratory rate (P > .05).ConclusionsDuring the COVID-19 pandemic, protective surgical face masks can be used safely in the postoperative period for pediatric patients aged 3 to 10 years.     

Acute physiologic effects of nasal and full-face masks during noninvasive positive-pressure ventilation in patients with acute exacerbations of chronic obstructive pulmonary disease

OBJECTIVE: To assess the efficacy of and patient tolerance for nasal and full-face masks during noninvasive positive-pressure ventilation (NPPV) with patients suffering acute exacerbations of chronic obstructive pulmonary disease. SETTING: A respiratory medicine ward of a referral hospital. METHODS: Fourteen patients were randomized to 2 groups. Seven used nasal masks and 7 used full-face masks. We used a portable ventilator and recorded arterial blood gases and indices of respiratory muscle effort before and after 15 min of NPPV. Patient tolerance was scored as follows: no tolerance (mask had to be withdrawn before the study period ended) = 0 points; poor tolerance (patient complained of discomfort from the ventilation devices but nevertheless remained compliant) = 1 point; fair tolerance (patient seemed uncomfortable but did not complain) = 2 points; excellent tolerance (patient felt better than before beginning NPPV) = 3 points. RESULTS: The groups were comparable in clinical and pulmonary function variables at baseline. NPPV improved both arterial blood gases and the indices of respiratory effort, with no significant differences between the groups. During NPPV the group that used full-face mask had a greater decrease in respiratory rate, but no other differences. NPPV was well tolerated in both groups. CONCLUSIONS: In patients suffering acute exacerbations of chronic obstructive pulmonary disease NPPV improves arterial blood gases and respiratory effort indices regardless of the type of mask used.     

经鼻气管内吸痰法在肺心病急性加重期患者中的应用研究

目的 探讨经鼻气管内吸痰方法在慢性肺心病急性加重期患者中的应用及其吸痰较果.将在我院住院治疗的慢性肺心病急性加重期患者100例随机分为观察组(50例)与对照组(50例)观察组采用经鼻气管内吸痰方法吸痰,对照组采用经鼻腔/口腔直接吸痰法(常规吸痰法)观察两种吸痰方法对24 h吸痰次数和吸痰总量、黏膜损伤的发生及对血氧饱和度和心肌耗氧量的影响.结果 观察组吸痰次数和总量、黏膜损伤的发生及吸痰方法对血氧饱和度和心肌耗氧量的影响与对照组相比均有显著性差异(P<0.05).实验组吸痰后与吸痰前比较HR、SBP和心肌耗氧量显著降低,差异有统计学意义(P<0.05) 吸痰后实验组SpO2高于对照组(P<0.05).结论 气管内吸痰法效果明显优于传统吸痰法.能彻底清除潴留的痰液,改善通气功能,减轻吸痰所致的低氧血症和气道黏膜损伤,降低心肌耗氧量,提高血氧饱和度.

Abstract：

Objective To explore the application and effect of sputum suction by tracheal intubation via nasal approach on patients with acute deteriorating chronic cor-pulmonale.Methods A total of 100 cases of patients with acute deteriorating chronic cor-pulmonale in our hospital were randomly divided into observation group ( 50 cases ) and control group (50 cases ). The observation group was received sputum suction by tracheal intubation via nasal.Control group was sputum drainage via nasal directly.The times and the quantity of sputum drainage in 24 hours and the effect on oxyhemoglobin saturation and myocardial oxygen consumption were observed.Results As compared with control group, there were significant difference in observation group as following :the times and the quantity of sputum drainage in 24 hours,the occurrence of mucosa injury, the effect on oxyhemoglobin saturation and myocardial oxygen consumption. There were statistical differences before and after aspiration of sputum in HR, SBP and myocardial oxygen consumption. Those of observation group were better than those of control group.Conclusions The effect of sputum suction by tracheal intubation via nasal approach was better than that of traditional way of sputum suction. It could clean the sputum retention, improve ventilation function, reduce hypoxemia and mucosa injury caused by suction, reduce myocardial oxygen consumption, improve oxyhemoglobin saturation.     

不同雾化吸入对脑出血开颅术后病人血氧饱和度的影响

[目的]探讨氧气雾化吸入和常规超声雾化吸入对全身麻醉脑出血术后血氧饱和度的影响.[方法]将64例脑出血开术后病人分为A组和B组各32例,A组病人使用氧气雾化吸入,B组病人使用常规超声雾化吸入,比较两组病人雾化吸入前后血氧饱和度的变化.[结果]A组病人治疗后血氧饱和度上升较B组明显,差异有统计学意义(P<0.05).[结论]氧气雾化吸入对提高脑出血开颅术后病人血氧饱和度优于常规超声雾化吸入.     

Time to Equilibration of Oxygen Saturation Using Pulse Oximetry

Objective: To determine the time it takes for O₂, saturation measured by pulse oximetry to equilibrate after a change is made in supplemental O₂, administered by nasal cannula in patients with cardiac and pulmonary disease.
Methods: A prospective, observational study of a convenience sample of 51 patients treated in a university-affiliated ED with nasal cannula O₂. Patients were placed on and/or subsequently taken off O₂ via nasal cannula set at 2 or 4L/min based on clinical indications. Oxygen saturation was measured at l-minute intervals over a 30-minute period using finger-probe pulse oximetry. Of the 51 patients in the study, 43 were monitored while O₂, treatment was initiated and 18 were monitored when it was discontinued.
Results: Most (95%) of the patients placed on O₂, attained equilibration of O₂, saturation within 3.5 minutes. Most (95%) of the patients taken off supplemental O₂, attained equilibration of O₂, saturation within 4.5 minutes.
Conclusion: The interval to equilibration of O₂, saturation in patients receiving O₂ by nasal cannula is considerably shorter than the 20–30 minutes generally suggested. Adequacy of O₂, supplementation should be assessable much sooner than was previously taught.     

不同气道管理方式下静脉全身麻醉对输尿管钬激光治疗输尿管结石的影响

目的分析面罩复合鼻咽通气道与喉罩通气模式下实施静脉全身麻醉对输尿管钬激光治疗输尿管结石的影响。方法选取2019年1月至2020年6月到该院进行输尿管结石治疗的患者160例,均行静脉全身麻醉下输尿管镜钬激光碎石术。采用随机、双盲法将其分为面罩复合鼻咽通气道组(S1组)和喉罩组(S2组),每组80例。比较并分析两组患者平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO₂)、手术时间、术后康复时间、不良反应率、结石清除率、治疗优良率及患者满意度等。结果组内比较,两组患者置入喉罩或者鼻咽通气道(面罩)时刻(T1)的MAP、HR均明显低于麻醉诱导前时刻(T0)和拔出时刻(T2),差异有统计学意义(P<0.05),各时刻SpO₂差异无统计学意义(P>0.05);组间比较,S1组T1时刻MAP较S2组低,差异有统计学意义(P<0.05),HR、SpO₂差异无统计学意义(P>0.05);两组手术时间、不良反应率及患者满意度比较,差异有统计学意义(P<0.05);术后康复时间、结石清除率以及优良率比较,差异无统计学意义(P>0.05)。结论与喉罩相比,面罩复合鼻咽通气道静脉全身麻醉应用于输尿管钬激光治疗输尿管结石,对血流动力学影响较小,能明显减少术后黏膜损伤等并发症,提高患者的满意度,且通气效果明显,实施简单易行。     

面罩与鼻罩在无创呼吸治疗AECOPD并发呼吸衰竭患者中的疗效对比

目的：探讨面罩与鼻罩在无创呼吸治疗AECOPD合并呼吸衰竭患者中的疗效对比。方法：将100例AECOPD患者并发呼吸衰竭的患者随机分为无创呼吸面罩治疗组（n=50）,鼻罩治疗组（n=50）。观察两组疗效：血气24hPH、PaO2、PaCO2、总有效率及住院时间、不良反应。结果：面罩治疗组与鼻罩治疗组在疗效、血气指标、心率、呼吸及住院时间无差异,但在不良反应方面,鼻罩组明显较面罩组减少。结论：对于AECOPD并发有呼吸衰竭的患者,在临床上更易优先推广鼻罩在无创呼吸中应用。