共查询到18条相似文献,搜索用时 515 毫秒
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目的:本文提出了用导数火焰原子吸收法测定中成药儿康宁中的微量铁、锌、钙的方法。方法:利用自制导数测量装置与火焰原子吸收分光光度计连接,对中成药儿康宁中的微量元素铁、锌、钙进行了测定。结果:检验出铁、锌、钙的含量分别为0.03939,0.0406,0.123mg·ml-1。结论:表明导数火焰原子吸收法具有较高的灵敏度、较低的检测限和较好的精密度,是一种测定中成药儿康宁中微量元素含量的较好方法 相似文献
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目的:探讨自备井水和污水中微量元素的快速测定方法。方法:直接蒸发浓集样品后,加入抑制剂测定。结果:镉、铅、锰、铜、锌、铁、铬、钴、镍九种元素测定结果标准偏差为0.001~0.003,相对标准偏差(RSD)为0.54%-1.30%.回收率为90%~110%。结论:火焰原子吸收分光光度法(AAS法)测定井水和污水中微量元素灵敏度较高,精密度好,准确度好,在实际工作中有一定的推荐应用价值。 相似文献
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悬浮液进样—火焰原子吸收光谱法测定中草药中的微量锰 总被引:12,自引:1,他引:11
目的:将悬浮液进样技术应用于火焰原子吸收光谱法,建立用原子吸收法测定中草药中微量元素的快速分析新方法。方法:将样品粉碎、悬浮在琼脂胶体中制成悬浮液,取适量样品悬浮液配制成试液,在试液中加入钙盐溶液以消除化学干扰。将试液喷入空气-乙炔火焰中,以空白溶液为参比,用标准加入法测定。结果:已用本方法成功地测定了当归、川芎及川乌中的锰,测定结果与灰化法-火焰原子吸收法一致,相对误差小于±20%,t检验表明2种方法之间无显著性差异。方法简便、快速、准确。结论:用悬浮液进样法取代灰化法进行样品前处理,以火焰原子吸收光谱法测定中草药中的锰是可行的。 相似文献
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目的:研究塞曼效应背景校正的火焰和石墨炉原子吸收法测定胶囊中铬的影响。方法:采用微波消解仪对胶囊壳样品进行消解,在波长359.3 nm下,灯电流7.5 mA;狭缝宽1.3 nm,塞曼背景校正,分别采用塞曼火焰原子吸收和石墨炉原子吸收法进行测定。结果:火焰原子吸收法:线性范围0.04~1.0 mg.mL-1;相关系数为0.9998,检测限5.26 ng.mL-1,RSD为0.68%~1.0%,加样回收率为100.0%~116.7%;石墨炉原子吸收法:线性范围为1~20 ng.mL-1,相关系数为0.9998,检测限为0.26 ng.mL-1,RSD为1.7%~4.9%,加样回收率为98.2%~105.6%。结论:塞曼火焰原子吸收法简便、快捷,能满足大量样品筛选及企业内部质控筛选与定值;石墨炉原子吸收法检测限较前者低,准确度较高。 相似文献
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目的:建立测定重组人胰岛素中锌的火焰原子吸收分光光度法。方法:样品经溶解后,采用火焰原子吸收分光光度法,利用锌元素的特征吸收波长(213.9nm)测定重组人胰岛素锌。结果:锌在0~0.8μg/ml范围内浓度与吸光度相关系数为0.9993(n=6),加标回收率98.6%~103.8%。结论:该方法操作简便,干扰少,可用于重组人胰岛素锌的测定。 相似文献
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目的 对比研究金诃脑血康与治疗19种心脑血管的中成药中微量元素的含量.方法 采用火焰原子吸收分光光法测定金诃脑血康与19种心脑m管类药物中镉、铬、钴、铜、铁、镁、锰、镍、铅、锌10种微量元素的含量.结果 心脑血管类药物中含有丰富的铁、铜、镁、锰、锌、钴、铬等微量元素.为探讨中成药中微量元素与治疗心血管疾病的关系提供了有用的数据.结论 所建方法简便、准确、重复件好,可用于金诃脑血康的质量控制. 相似文献
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5种常见中草药中有害元素铅、镉、铜的含量测定与分析 总被引:1,自引:0,他引:1
目的测定不同产地的5种常用中草药(黄芪、丹参、甘草、西洋参、金银花)中金属元素铅(Pb)、镉(Cd)和铜(Cu)的含量。方法 采用湿法消解处理样品,以火焰吸收和石墨炉原子吸收分光光度法测定Pb、Cd和Cu的含量。结果各产地5种中草药Pb、Cd和Cu含量的平均值依次为:黄芪3.77、0.191、5.82mg·kg-1,丹参6.24、0.194、12.07mg·kg-1,甘草4.72、0.177、7.59mg·kg-1,西洋参4.96、0.218、8.87mg·kg-1,金银花6.59、0.180、15.55mg·kg-1。结论不同产地的中草药大部分含有害金属元素,采取有效的质量控制是必要的。 相似文献
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On-line preconcentration and determination of chromium in parenteral solutions by flow injection-flame atomic absorption spectrometry 总被引:1,自引:0,他引:1
Wuilloud GM Wuilloud RG de Wuilloud JC Olsina RA Martinez LD 《Journal of pharmaceutical and biomedical analysis》2003,31(1):117-124
An on-line chromium preconcentration and determination system implemented with flame atomic absorption spectrometry (FAAS) associated to flow injection (FI) was studied. For the retention of chromium, 4-(2-Thiazolylazo)-resorcinol (TAR) and Amberlite XAD-16 were used, at pH 5.0. The Cr-TAR complex was removed from the micro-column with ethanol. An enrichment factor of 50 was obtained for the preconcentration of 50 ml of sample solution. The detection limit value for the preconcentration of 50 ml of aqueous solution of Cr was 20 ng l(-1). The precision for ten replicate determinations at the 5 microg l(-1) Cr levels was 2.9% relative standard deviation (RSD), calculated from the peak heights obtained. The calibration graph using the preconcentration system for chromium was linear with a correlation coefficient of 0.9997 at levels near the detection limits up to at least 100 microg l(-1). The method was successfully applied to the determination of chromium in parenteral solution samples. 相似文献
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目的:建立药品和保健品软胶囊壳中有害元素铬的检测方法。方法采用石墨炉-原子吸收分光光度法进行测定,波长357.9 nm ,狭缝宽度为0.7 nm ,氘灯作为背景校正,微波消解对样品进行前处理。结果回归方程:Y=0.01016 X+0.00132,在0~50μg · L -1范围内线性关系良好(r=0.9989),方法的检出限为0.02 mg · kg -1,定量限为0.08 mg · kg -1。高中低3个质量浓度平均回收率分别为101.4%,100.8%和99.7%,RSD分别为1.9%,2.1%和3.2%。结论该方法简便、准确、灵敏度高,适用于药品和保健品软胶囊壳中有害元素铬的含量测定。 相似文献
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原子吸收法测定中药材中6种重金属及有害元素的残留量 总被引:8,自引:0,他引:8
目的:建立中药中6种重金属及有害元素(铅、镉、砷、汞、铜、锑)的检测方法,测定6种中药材中的残留含量。方法:样品经微波消解,采用石墨炉原子吸收法测定铅、镉、锑;采用氢化物-原子吸收法测定砷;采用冷原子吸收法测定汞;采用火焰原子吸收法测定铜,并对测定方法进行了方法学考察。结果:6种重金属及有害元素的回收率为79.0%~125.8%,RSD 为0.8%~14.6%。结论:该方法简便,准确,可较好地用于中药重金属及有害元素残留量的测定。 相似文献
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Determination of lipid bilayer/water partition coefficient of new phenothiazines using the second derivative of absorption spectra method. 总被引:1,自引:0,他引:1
Andrzej Po?a Krystyna Michalak Anna Burliga Noboru Motohashi Masami Kawase 《European journal of pharmaceutical sciences》2004,21(4):421-427
The partition coefficients (K(p)) between lipid bilayer of phosphatidylcholine (PC) vesicles and buffer for five new phenothiazines were determined using the second derivatives of ultraviolet absorption spectra. The lambda(max) of absorption band for each of the investigated phenothiazine derivatives (PDs) was shifted to the longer wavelengths in the presence of PC vesicles with increasing of lipid concentration. As a result of light scattering in liposome suspension no isosbestic point could be observed in absorption spectra. However, the background signal could be eliminated using the method of second derivative of absorption spectra. In the second derivative of absorption spectra two isosbestic points were observed. Changes of intensity (Delta D) of second derivative of absorption spectra at the lambda(max) (wavelength of absorption maximum for drug in buffer) caused by the increase in lipid concentration were measured for set of phenothiazine derivatives. K(p) for these drugs were calculated from the relationship between Delta D and lipid concentration. The K(p) values for all studied phenothiazine derivatives are in the order of magnitude of 10(5) and they increase about 1.7-fold when length of the alkyl phenothiazine chain was enhanced by addition of the each next one (-CH(2)) group. Substitution of -H atom by -CF(3) group at position 2 of phenothiazine ring results in 3.5-fold increase in K(p) values. 相似文献
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目的 研究地龙与地龙配方颗粒中铅(Pb)的含量。方法 采用于法处理样品,火焰原子吸收法测定。结果 相关系数为0.9998。回收率为93.4%~98.7%。地龙配方颗粒中铅的含量明显低于地龙药材。结论 方法简便,重现性好,可用于中药配方颗粒及中药制剂中铅的含量测定。 相似文献