三角吻合在完全腹腔镜远端胃癌根治术中的应用研究

目的 对比分析远端胃癌根治术中全腹腔镜下三角吻合与腹腔镜辅助Brillroth Ⅰ式吻合的近期疗效,探讨三角吻合技术的应用价值.方法 回顾性分析2013年3月至2014年2月开展的50例全腹腔镜下远端胃癌根治术加三角吻合的临床资料（三角吻合组）,并以同期开展的43例腹腔镜辅助远端胃癌根治术加Brillroth Ⅰ吻合作为对照（BⅠ吻合组）,比较两组患者的手术相关指标和术后并发症发生情况.结果 两组手术时间、术中出血量、淋巴结清除数、术后肛门排气时间、并发症发生率和术后住院天数比较,差异均无统计学意义（均P＞0.05）;三角吻合组切口长度[（3.4±0.4）cm]和术后第1天疼痛评分[（3.1±1.0）]小于BⅠ吻合组[（6.9±0.8）cm和（4.6±1.4）],差异均有统计学意义（均P＜0.05）.结论 全腹腔镜下远端胃癌根治术三角吻合技术安全可行,在切口美观和舒适度方面较腹腔镜辅助下Brillroth Ⅰ式吻合更有优势。     

三角吻合在全腹腔镜远端胃癌根治术中的应用

目的 探讨三角吻合技术在全腹腔镜下远端胃癌根治术中应用的安全行、可行性和临床疗效.方法 对56例远端胃癌患者施行全腹腔镜下胃癌根治术并行残胃十二指肠三角吻合.结果 56例手术均获成功.手术时间（169.4±32.3） min;三角吻合时间（22.4 ±9.2） min;术中出血量（76.6±32.7）ml;淋巴结清扫总数（34.1±12.3）枚/例,进食流质时间（3.4±1.5）d,术后住院时间（8.4±2.6）d;全组切缘无肿瘤残留;全组均未出现吻合口出血、吻合口漏及吻合口狭窄或吻合口相关并发症.结论 三角吻合技术应用于全腹腔镜下远端胃癌根治术是安全可行的,近期效果满意,远期疗效需进一步观察研究.     

三角吻合技术在早期远端胃癌根治术中应用要点

正2002年,日本学者Kanaya等[1]首次提出了胃十二指肠全腹腔镜下三角吻合技术,该技术仅利用直线切割闭合器即可完成胃与十二指肠端端吻合。在此基础上Huang等[2]进一步改良了三角吻合术。目前,胃十二指肠三角吻合技术逐渐获得国内外多家医疗中心的认可和开展。本文将介绍在远端胃癌根治术中应用三角吻合技术的相关要点。     

全腹腔镜远端胃癌根治术Delta吻合技术要点

正全腹腔镜下的胃癌根治术在牵拉、暴露和手术视野等方面较腹腔镜辅助更有优势,微创效果更佳~([1-4])。因此,越来越受到腹腔镜外科医师的关注。然而,对于行远端胃大部切除的胃癌病人,全腹腔镜下的胃十二指肠吻合一度被认为存在技术上的难点。Kanaya等~([5])提出了全腹腔镜下远端胃癌根治术Delta吻合(delta-shaped gastroduodenostomy,DSG),该技术完全在腹腔镜下应用直线切割闭合器完成残     

三角吻合技术在全腹腔镜下胃远端癌根治术中的应用

目的 探讨三角吻合技术在全腹腔镜下胃远端癌根治术中的可行性和临床疗效.方法 回顾性分析2012年11-12月间福建医科大学附属协和医院实施的18例全腹腔镜胃远端癌根治术并残胃十二指肠吻合(三角吻合)病例的临床资料.三角吻合是完全在腹腔镜下应用直线切割闭合器完成残胃和十二指肠后壁的功能性端端吻合,再利用直线切割闭合器闭合共同开口后,吻合口内部的缝钉线呈现为三角形.结果 18例患者均成功施行全腹腔镜下胃远端癌淋巴结清扫(D1+或D2)及三角吻合.手术时间(156.3±38.5) min,三角吻合耗时(24.6±11.2) min.肿瘤距上切缘(5.8±2.4) cm,距下切缘(4.1±2.7) cm,上、下切缘病理结果均未见癌残留.术中出血量(70.7±43.8) ml,淋巴结清扫数目(32.4±12.0)枚/例.术后首次下床活动时间(1.8±0.9)d,肛门排气时间(3.1±1.2)d,进食流质时间(3.6±1.7)d,术后住院时间(9.6±2.5)d.术后1例患者出现乳糜瘘伴腹腔感染;全组均未出现吻合口出血、吻合口狭窄或吻合口瘘等吻合口相关并发症.结论 三角吻合技术应用于全腹腔镜下胃远端癌根治术是安全可行的,近期疗效满意.     

胃空肠“裤形吻合”在腹腔镜辅助远端胃癌根治术中的应用

目的探讨胃空肠“裤形吻合”在腹腔镜辅助远端胃癌根治消化道重建中应用的安全性和可行性。方法2018年6~12月,采用胃空肠裤形吻合完成腹腔镜远端胃癌根治后毕Ⅱ式消化道重建96例。腹腔镜下胃切除完成后,上腹正中做5~7 cm切口。在拟行胃空肠吻合前,用直线切割闭合器在空肠肠壁开口处行空肠输入输出襻侧侧吻合,用圆形吻合器吻合输入输出襻共同开口于残胃。结果96例手术均获成功,切口长度4.8~6.8 cm(平均5.3 cm),手术总时间125~235 min(平均155.8 min),消化道重建时间15~33 min(平均22 min),术中出血量20~200 ml(平均50 ml),术后排气时间3~5 d(平均3.5 d),进流食时间2~3 d(平均2.7 d),进半流食时间4~6 d(平均5.5 d),术后住院时间7~12 d(平均8.2 d)。围手术期无严重并发症。术后随访3~9个月(平均6个月),1例小肠梗阻,保守治疗,无其他并发症。结论胃空肠裤形吻合操作简单、快捷,不增加手术复杂度,用于腹腔镜远端胃癌根治毕Ⅱ式消化道重建安全、可行。     

H形吻合在腹腔镜下远端胃癌根治术中的应用

目的:评价H形吻合在腹腔镜下远端胃癌根治术后消化道重建中的临床效果。方法:回顾分析2013年1月至2015年6月152例行腹腔镜下远端胃癌根治术且有完整随访资料患者的临床资料,根据其消化道重建方式分为:H形吻合组(n=20)、毕Ⅰ式吻合组(n=53)、毕Ⅱ式吻合组(n=58)及Roux-en-Y吻合组(n=21)。4组患者在年龄、性别、肿瘤大小、肿瘤分期及分级方面差异均无统计学意义。结果:H形吻合组手术时间及重建时间较毕Ⅰ式有所增加,且重建时间两者差异有统计学意义,与毕Ⅱ式吻合组差异无统计学意义,较Roux-en-Y吻合组明显缩短,差异有统计学意义;H形吻合组术中出血量少于毕Ⅰ式吻合组,差异有统计学意义。术后每日胃肠减压量、术后进流质饮食时间明显少于其他三组,差异有统计学意义。H形吻合组术后排气时间明显缩短,与Roux组相比差异有统计学意义。H形吻合组无术后吻合口狭窄、出血、吻合口漏等并发症发生。结论:H形吻合能明显降低手术时间,减少术后排气时间、胃潴留、吻合口梗阻等并发症,是远端胃癌根治术后理想的消化道重建方式。     

改良三角吻合应用于腹腔镜远端胃癌根治术54例临床报告

目的探讨腹腔镜远端胃癌D2根治术采用改良三角吻合技术施行消化道重建的可行性、安全性及临床疗效。方法收集自2014年1月至2016年1月间54例病例资料,均施行腹腔镜远端胃癌D2根治术并采用改良三角吻合技术施行消化道重建。结果 54例成功施行手术。吻合时间为(26.0±4.5)min,术中出血量中位数106 ml(75~158 ml),切口长度为(2.0±1.5)cm。术后第1天C反应蛋白为(19.0±6.4)mg/L,疼痛评分(VAS评分)第1天为(4.1±0.9)分、第2天为(1.7±0.7)分,肛门排气时间为(2.3±1.7)d,拆线时间为(6.4±1.5)d,术后住院时间为(8.5±1.9)d。术后未发生吻合口相关并发症(吻合口漏、吻合口狭窄、吻合口出血),出现肺部感染1例。结论腹腔镜胃远端癌D2根治术中采用改良三角吻合技术施行消化道重建安全可行,临床效果满意。是远端胃癌可考虑采取的消化道重建方式。     

全腹腔镜下远端胃癌根治术三角吻合术

先确定肿瘤位置,沿横结肠边缘超声刀游离横结肠系膜前叶,向右游离至结肠肝曲,左至脾曲,离断网膜左血管,清扫4sb,4d淋巴结;沿结肠中动脉及其分支分离,向上暴露肠系膜上静脉、右结肠静脉、胃网膜右静脉,骨骼化胃网膜右动脉于根部切断;裸化十二指肠下缘,暴露胃十二指肠动脉,肝总动脉胃左脾动脉和腹腔干,切断胃左动脉清扫第7.8.9.11p组淋巴结;向下剥离裸化肝十二指肠韧带,清扫第12a组淋巴结,并向上彻底清扫第1,3,5组淋巴结,使用内镜下直线切割吻合器离断十二指肠球部,胃体。扩大脐部穿刺孔至取出标本,缝合切口。重建气腹,行胃大弯和十二指肠后壁三角吻合。     

全腔镜下吻合技术在腹腔镜胃癌根治术中的应用

目的 探讨全腔镜下吻合技术在腹腔镜胃癌根治术中的安全性及可行性.方法 回顾分析2012年7月-2013年7月吉林大学第二医院胃肠外科实施腹腔镜胃癌根治术全腔镜下吻合（36例,全腔镜吻合组）与小切口辅助吻合（47例, 小切口辅助组）患者的临床资料,并对两组临床资料进行对比分析.结果 83例患者均成功实施手术,无一例中转开腹.小切口辅助组切口长度为（7.1±0.9） cm,全腔镜吻合组为（2.6±0.4） cm.小切口辅助组吻合时间为（70.9±9.0） min,全腔镜吻合组为（29.1±4.9） min.术后小切口辅助组中度疼痛者6例,余41例为重度疼痛;全腔镜吻合组中度疼痛者29例,余7例为重度疼痛.小切口辅助组术后发生吻合口瘘1例,全腔镜吻合组未出现吻合口瘘及吻合口出血等并发症.结论 全腔镜下吻合技术在腹腔镜胃癌根治术中安全、可行,与小切口辅助吻合相比具有手术时间短和疼痛感减轻等优势.     

An Effective Duodenum Bulb Mobilization for Extracorporeal Billroth I Anastomosis of Laparoscopic Gastrectomy

Background Data  Extracorporeal circular-stapled Billroth I (B-I) anastomosis is difficult in patients with obesity, a large body shape, or small remnant stomach, as it requires the duodenal stump to be lifted outside of the wound. The aim of this study was to evaluate the feasibility of circular-stapled B-I reconstruction for laparoscopy-assisted distal gastrectomy (LADG) with effective duodenal mobilization. Methods  Between March 2005 and December 2007, 199 patients with early gastric cancer underwent LADG with B-I reconstruction in the Department of Gastrointestinal Surgery at the Cancer Institute. The greater omentum, comprised of four membrane layers, was completely dissected for effective duodenal bulb mobilization to allow easy performance of extracorporeal end-to-end gastroduodenostomy. Several clinicopathophysiological features relating to anastomosis complications, including anastomotic leakage, stenosis, bleeding, and ulcers, were evaluated. Results  The success rate of extracorporeal circular-stapled B-I anastomosis was 100% for the 199 patients, 24% of whom had a body mass index greater than 25. The rate of anastomosis-related postoperative complications was 2%. Anastomotic leakage was not observed in this study. Anastomotic stenosis was observed in 2 (1%) patients, anastomotic bleeding was observed in 1 (0.5%) patient, and anastomotic ulcer was diagnosed in 1 (0.5%) patient. All these complications were managed conservatively. There was no postoperative mortality. Conclusions  Feasible duodenal bulb mobilization by complete dissection of the greater omentum allows easy performance of extracorporeal B-I anastomosis and minimizes complications related to anastomosis in LADG.     

Totally Laparoscopic Distal Gastrectomy Using the Hand-Sewn Billroth-I Anastomotic Technique: Report of a Case

The development of more sophisticated instruments has enabled advanced laparoscopic surgery. We recently devised a totally laparoscopic method of performing Billroth-I hand-sewn anastomosis and established this technique in an animal training model. This report presents the case of a 50-year-old man in whom totally laparoscopic distal gastrectomy was successfully performed for gastric cancer, using the hand-sewn Billroth-I anastomotic technique. The patient was admitted with gastric cancer in the angle of the stomach and underwent laparoscopic distal gastrectomy with radical lymph node dissection. After the resected specimen was extracted through the small incision, a Billroth-I anastomosis was performed laparoscopically by the hand-sewn technique using the Albert-Leinbert method. The patient was discharged on the seventh postoperative day without any intra- or postoperative complications. Laparoscopic hand-sewn anastomosis was performed safely and allowed for quick recovery and good cosmesis in this patient. Received: February 4, 2002 / Accepted: September 3, 2002 Reprint requests to: S. Takiguchi     

Prophylactic Laparoscopic Gastrectomy for Hereditary Diffuse Gastric Cancer: A Case Series in a Single Family

Background:

Hereditary diffuse gastric carcinomas (HDGCs) are particularly troubling because of autosomal dominant heritance, high penetrance, early age of onset, and a lack of effective treatment once symptomatic. HDGC is further complicated by difficulty of effective screening. Gastrectomy provides definitive treatment for CDH1 mutation-positive patients. Attempting to minimize the morbidity and mortality of this procedure via a laparoscopic approach is appropriate.

Methods:

Six consanguineous patients, 21 to 51 years of age, were identified as carriers of the CDH1 gene mutation. All of the patients'' gastric mucosa was normal by endoscopic appearance and biopsy. After appropriate multispecialty counseling, all patients elected to undergo a laparoscopic total gastrectomy. Demographics, genealogy, operative approach, outcomes, and pathology were reviewed.

Results:

All gastrectomies were completed using a laparoscopic approach. Gross examination of resected stomachs was unremarkable. Histological examination demonstrated multiple foci of invasive signet ring adenocarcinoma in all patients. There were no anastomotic leaks, one small bowel obstruction requiring reoperation, and one esophageal stricture requiring dilation.

Conclusions:

This series demonstrates the utility and safety of the laparoscopic approach for prophylactic total gastrectomy for carriers of the CDH1 gene mutation. It serves to highlight that patients with CDH1 mutations may be more likely to undergo gastrectomy if they are offered the lower risk laparoscopic approach.     

腹腔镜下全子宫切除与腹腔镜辅助阴式子宫切除的比较

目的对比分析腹腔镜全子宫切除术（total laparoscopic hysterectomy,TLH）和腹腔镜辅助阴式子宫切除术（1aparoscopic-assisted vaginal hysterectomy,LAVH）的临床价值。方法回顾性比较2007年1月-2012年1月1034例TLH和LAVH的手术时间、出血量、排气时间、住院时间、子宫重量及术后病率、泌尿系损伤、肠管损伤、血管损伤等并发症。结果1034例手术均顺利完成,无中转开腹。TLH组手术时间（80．4±19．2）min与LAVH组（80．2±17．8）min无显著性差异（t=0．166,P=0．868）;LAVH组出血量（53．4±14．3）ml显著多于TLH组（49．84-16．8）ml（t=-3．596,P=0．000）;LAVH组排气时间（27．1±5．5）h显著长于TLH组（24．6±5．1）h（t=-7．059,P=0．000）;LAVH组住院时间（5．4±1．2）d显著长于TLH组（5．1±1．4）d（t=-3．581,P=0．000）。LAVH组切除的子宫重量（286．1±28．2）g,与TLH组（279．6±27．4）g有显著性差异（t=-3．528,P=0．000）。术后病率TLH组1．4％和LAVH组1．7％无显著性差异（∥=0．122,P=0．727）。术后泌尿系统损伤1例（LAVH组）、肠管损伤1例（TLH组）、血管损伤2例（2组各1例）,2组并发症发生率无统计学差异[0．6％（2／345）vs．0．3％（2／689）,X2=0．031,P=0．861]。术后随访0．5～5年,平均3．9年,无切口感染、切口疝、出血等并发症发生。结论TLH和LAVH均是安全可行的。     

生物可降解吻合环在胃切除术后消化道重建中的应用

目的总结生物可降解吻合环在胃切除术后消化道重建中的应用经验. 方法全胃或胃部分切除后,用吻合环完成消化道重建32例,包括胃空肠吻合和空肠端侧吻合. 结果本组均一次性获得成功,平均完成一个吻合所需时间为10 min,无吻合口瘘、出血及感染.术后1个月内吻合环自行溶解,经肠道排出体外.随访3～12个月,复查胃镜或钡餐无一例出现吻合口狭窄等并发症. 结论在胃切除后消化道重建中,与传统手工吻合相比,吻合环具有方便、快捷、可靠等优点,大大提高了操作效率,缩短了手术时间,并且有利于防止吻合口瘘或狭窄等并发症.只要病人经济条件允许,应尽量使用.     

Readmission Following Laparoscopic Sleeve Gastrectomy

Methods:Data on 343 consecutive LSG operations performed from February 2010 to May 2014 by a single surgeon (PG) were analyzed. Patients readmitted within 30 d were compared to the remaining patients by using Student''s t test for continuous variables and the χ² test for categorical variables.Results:All LSGs were completed laparoscopically with no conversions to open procedures. There were no reoperations, leaks, perioperative hemorrhages, or mortalities. Twelve patients (3.5%) were readmitted; 1 was readmitted twice. There were no identified risk factors for readmission, including patient demographics, comorbidities, and perioperative factors. Notably, 7 (7%) readmissions occurred in the initial 100 patients and 5 (2%) in the remaining 243 patients (P = .04). Clinical pathways were modified after the initial 100 patients; routine contrast esophagograms were no longer performed, and a 1-day routine postoperative stay was adopted. Operative time also decreased from 94.2 ± 23.8 to 78.2 ± 20.0 min (P < .001).Conclusions:Readmission rates after LSG remain in a range similar to those described for other laparoscopic bariatric procedures. Larger prospective studies are needed to identify patterns of complications and readmissions in patients undergoing LSG that may differ from other bariatric procedures.     

Mechanical-Stapled Versus Hand-Sutured Anastomoses in Billroth-I Reconstruction with Distal Gastrectomy

PURPOSE: In June 2000, we started performing mechanical-stapled anastomosis (MSA) for Billroth-I reconstruction (B-I) in distal gastrectomy. Thus, we performed a retrospective study to compare the clinical outcome of MSA and conventional hand-sutured anastomosis (HA). METHODS: We evaluated 103 patients who underwent a B-I reconstruction. The data we collected included operative time, operative blood loss, time until oral intake, postoperative hospital stay, and anastomotic and general complications. We also examined the remnant stomach by endoscopy and classified it according to the Residue, Gastritis, Bile (RGB) criteria. RESULTS: The operative time was significantly shorter with MSA than with HA, but there were no other significant differences between the two groups. The RGB classification showed that there was more residual stomach content after MSA than after HA. The incidence of gastritis and bile reflux was not significantly different between the two procedures. CONCLUSION: The operative time for B-I reconstruction with distal gastrectomy was significantly shorter with MSA than with HA. While there were no significant disadvantages in the incidence of complications associated with MSA compared with HA, MSA resulted in more residue in the remnant stomach. The findings of this study showed the advantages and disadvantages of MSA, and suggest that MSA and HA are equivalent as anastomotic procedures in B-I reconstruction.