脊椎嗜酸性肉芽肿（附14例报告）

报道经病理证实的脊椎嗜酸性肉芽肿１４例的治疗结果。其中１２例随访１～１８年，平均４年８个月，９例不全瘫痪者中，７例完全恢复，２例部分恢复；１例完全瘫痪者部分恢复。通过临床资料分析，着重阐述了脊椎嗜酸性肉芽肿的诊断和治疗方法的选择，认为有神经根或脊髓受压者，应以手术治疗为主，结合放疗或化疗；而无神经根或脊髓受压者，以放疗为主，结合化疗。早期诊断和正确的治疗是防止瘫痪发生的关键。     

Eosinophilic granuloma of the spine with neurological deficit

A case of a 14-year-old boy with a solitary eosinophilic granuloma of the thoracic spine, with paraplegia secondary to the collapse of the vertebra and peridural spread of tumor, is presented. It is the 14th case recorded in literature to this date. This disease is self-limiting, and there is no role of steroids or radiotherapy observed.     

脊柱嗜酸性肉芽肿伴运动神经麻痹的手术治疗

目的探讨脊柱嗜酸性肉芽肿伴运动神经麻痹患者的手术方式及疗效。方法对17例病理诊断为脊柱嗜酸性肉芽肿的患者行病灶切除及减压融合手术,并对患者资料进行研究。结果 17例患者手术均顺利完成。术后4周的Frankel评级,较术前均有一个等级及以上的改善,神经功能改善明显(P0.05)。术后随访期间,未发现复发及脊柱后凸畸形等并发症。结论对伴有运动神经麻痹的脊柱嗜酸性肉芽肿患者,病灶切除及减压融合手术,疗效确切,远期并发症发生率低。     

Eosinophilic granuloma of the hand

The first reported case of eosinophilic granuloma of the hand is presented. A slowly expanding lesion of the right third metacarpal shaft was treated by biopsy and curettage. Histological examination confirmed the presence of eosinophilic granuloma. A bone scan showed that it was a solitary lesion. There has been no evidence of recurrence of the lesion during follow-up. Eosinophilic granuloma is a rare disease of the mononuclear phagocyte system, representing one of the clinical manifestations of Langerhans-cell histiocytosis. The lesions are usually associated with the skull, femur, mandible and ribs; this condition has not been previously reported in the hand.