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1.
Malignant colorectal obstruction treated by means of self-expanding metallic stents: effectiveness before surgery and in palliation 总被引:34,自引:0,他引:34
PURPOSE: To determine the effectiveness and safety of metallic stents in the treatment of malignant colorectal obstruction before surgery and for palliation. MATERIALS AND METHODS: Eighty patients with acute malignant colorectal obstruction presumed to be malignant were treated by means of implanting self-expanding metallic stents. RESULTS: Stent placement was successful in 70 of the 80 patients and resolved bowel obstruction in 67 patients (96%). Two patients had colonic perforation and developed peritonitis 18 and 24 hours after stent placement; one patient died as a consequence. Thirty-three patients underwent elective surgery after 7 days +/- 3 (SD; range, 4-10 days), and adequate tumoral coverage and cleansing of the colon were observed in all patients. Stent placement was used as final palliative treatment in another 35 patients. Patient follow-up lasted a mean of 138 days +/- 93 (range, 36-334 days). The survival rate for the palliative group was 55% at 3 months, 44% at 6 months, and 25% at 9 months. The estimated primary stent patency rate was 91% at 3 and 6 months. CONCLUSION: Management of colorectal obstruction by using metallic stents was effective and safe, although colonic perforation is a potential complication. In cases of palliation, the method may obviate palliative colostomy. 相似文献
2.
Jung Gu Park Gyoo-Sik Jung Kyung Seung Oh Seon-Ja Park 《Cardiovascular and interventional radiology》2010,33(4):772-779
We evaluated the effectiveness of a double-layered polytetrafluoroethylene (PTFE)-covered nitinol stent in the palliative
treatment of malignant esophageal strictures. A double-layered PTFE-covered nitinol stent was designed to reduce the propensity
to migration of conventional covered stent. The stent consists of an inner PTFE-covered stent and an outer uncovered nitinol
stent tube. With fluoroscopic guidance, the stent was placed in 32 consecutive patients with malignant esophageal strictures.
During the follow-up period, the technical and clinical success rates, complications, and cumulative patient survival and
stent patency were evaluated. Stent placement was technically successful in all patients, and no procedural complications
occurred. After stent placement, the symptoms of 30 patients (94%) showed improvement. During the mean follow-up of 103 days
(range, 9–348 days), 11 (34%) of 32 patients developed recurrent symptoms due to tumor overgrowth in five patients (16%),
tumor ingrowth owing to detachment of the covering material (PTFE) apart from the stent wire in 3 (9%), mucosal hyperplasia
in 2 (6%), and stent migration in 1 (3%). Ten of these 11 patients were treated by means of placing a second covered stent.
Thirty patients died, 29 as a result of disease progression and 1 from aspiration pneumonia. The median survival period was
92 days. The median period of primary stent patency was 190 days. The double-layered PTFE-covered nitinol stent seems to be
effective for the palliative treatment of malignant esophageal strictures. We believe that the double-layer configuration
of this stent can contribute to decreasing the stent’s migration rate. 相似文献
3.
Jin Soo Choi Sung Wook Choo Kwang Bo Park Sung Wook Shin So-Young Yoo Ji Hye Kim Young Soo Do 《Korean journal of radiology》2007,8(1):57-63
Objective
We wanted to evaluate usefulness of uncovered stent in comparison with covered stent for the palliative treatment of malignant colorectal obstruction.Materials and Methods
Covered (n = 52, type 1 and type 2) and uncovered (n = 22, type 3) stents were placed in 74 patients with malignant colorectal obstruction. Stent insertion was performed for palliative treatment in 37 patients (covered stent: n = 23 and uncovered stent: n = 14). In the palliative group, the data on the success of the procedure, the stent patency and the complications between the two groups (covered versus uncovered stents) were compared.Results
The technical success rate was 89% (33/37). Symptomatic improvement was achieved in 86% (18/21) of the covered stent group and in 92% (11/12) of the uncovered stent group patients. The period of follow-up ranged from three to 319 days (mean period: 116±85 days). The mean period of stent patency was 157±33 days in the covered stent group and 165±25 days in the uncovered stent group. In the covered stent group, stent migration (n = 11), stent fracture (n = 2) and poor expansion of the stent (n = 2) were noted. In the uncovered stent group, tumor ingrowth into the stents (n = 3) was noted.Conclusion
Self-expanding metallic stents are effective for relieving malignant colorectal obstruction. The rate of complications is lower in the uncovered stent group than in the covered stent group. 相似文献4.
Soh KC Tay KH Tan BS Mm Htoo A Hg Lo R Lin SE 《Cardiovascular and interventional radiology》2008,31(3):604-609
Our aim was to review our experience with percutaneous antegrade ureteric stent (PAUS) placement and to determine if the routinely
conducted check nephrostogram on the day following ureteric stent placement was necessary. Retrospective review of patients
who had undergone PAUS placement between January 2004 and December 2005 was performed. There were 83 subjects (36 males, 47
females), with a mean age of 59.9 years (range, 22–94 years). Average follow-up duration was 7.1 months (range, 1–24 months).
The most common indications for PAUS placement were ureteric obstruction due to metastatic disease (n = 56) and urinary calculi (n = 34). Technical success was 93.2% (96/103 attempts), with no major immediate procedure-related complications or mortalities.
The Bard 7Fr Urosoft DJ Stent was used in more than 95% of the cases. Eighty-one of 89 (91.0%) check nephrostograms demonstrated
a patent ureteric stent with resultant safety catheter removal. Three check nephrostograms revealed distal stent migration
requiring repositioning by a goose-snare, while five others showed stent occlusion necessitating permanent external drainage
by nephrostomy drainage catheter reinsertion. Following PAUS placement, the serum creatinine level improved or stabilized
in 82% of patients. The serum creatinine outcome difference between the groups with benign and malignant indications for PAUS
placement was not statistically significant (p = 0.145) but resolution of hydronephrosis was significantly better (p = 0.008) in patients with benign indications. Percutaneous antegrade ureteric stent placement is a safe and effective means
of relief for ureteric obstruction. The check nephrostogram following ureteric stent placement was unnecessary in the majority
of patients. 相似文献
5.
Sandas Qi Hua Chou Ho-Young Song Jin Hyoung Kim Jung-Hoon Park Yong Fan Heuiran Lee Yong Sik Yoon Jin Cheon Kim 《Korean journal of radiology》2012,13(1):66-72
Objective
To evaluate the safety and effectiveness of a 20-mm diameter dual-design expandable colorectal stent for malignant colorectal obstruction.Materials and Methods
The study series included 34 patients with malignant colorectal obstruction who underwent implantation of a 20-mm dual-design expandable colorectal stent in our department between March 2009 and June 2010. The 20-mm dual-design expandable colorectal stent was placed by using a 3.8-mm delivery system that had 28-mm diameter proximal and distal ends. Among the 34 patients, stent placement for palliation was performed in 20 patients, while stent placement for bridge to surgery was performed in 14 patients.Results
A 97% (33 of 34) success rate was achieved for the stent placement. The perforation rate in the bridge to surgery group was 7% (1 of 14), compared to 0% (0 of 19) in palliative group. Migration occurred in one of 33 patients (3%) at 30 days after stent placement.Conclusion
The placement of a 20-mm diameter dual-design stent appears to be clinically safe and effective for the management of colorectal obstruction, with low perforation and migration rates. 相似文献6.
Malignant gastric outlet obstructions: treatment by means of coaxial placement of uncovered and covered expandable nitinol stents 总被引:5,自引:0,他引:5
Jung GS Song HY Seo TS Park SJ Koo JY Huh JD Cho YD 《Journal of vascular and interventional radiology : JVIR》2002,13(3):275-283
PURPOSE: To assess whether coaxial placement of uncovered and covered expandable nitinol stents overcomes the disadvantages of the increased migration rate seen with covered stents and the tumor ingrowth seen in uncovered stents in the treatment of malignant gastric outlet obstructions. MATERIALS AND METHODS: Two types of expandable nitinol stent were designed: an uncovered stent and a covered stent. Under fluoroscopic guidance, the uncovered and covered stents were placed coaxially with complete overlap in 39 consecutive patients with malignant gastric outlet obstruction caused by stomach cancer. Food intake capacity was graded on a scale of 0-4. Stent patency rate was estimated by the Kaplan-Meier method. RESULTS: Technical success rate was 97% (38 of 39 patients). After stent placement, food intake capacity improved at least one grade in 36 patients. Stent migration occurred in three patients (8%), that is, partial (n = 2) or complete (n = 1) upward migration of the inner covered stent into the stomach. Two of these patients were treated by placement of an additional covered stent. During the mean follow-up period of 134 days (range, 15-569 d), 10 patients developed recurrent symptoms of obstruction with tumor overgrowth being the most common cause. Nine underwent placement of an additional covered stent with good results. The median period of primary stent patency was 157 days (mean, 278 d). The 30-, 60-, and 180-day patency rates were 97%, 91%, and 39%, respectively. Four patients (10%) died within 1 month after the procedure. CONCLUSION: Coaxial stent placement technique seems to contribute to decreasing the migration rate of the stent and decrease the rate of recurrent obstruction by preventing or delaying tumor ingrowth. 相似文献
7.
Yong-Dong Li Ying-Sheng Cheng Ming-Hua Li Ni-Wei Chen Jun-Gong Zhao 《European journal of radiology》2010,73(3):566-571
Purpose
To prospectively evaluate the safety and clinical efficacy of a newly designed self-expandable metallic stent (SEMS) in the treatment of patients with acute malignant colorectal obstruction.Methods
Between April 2001 and October 2007, 52 patients with acute malignant colorectal obstruction were treated with a new designed SEMS as an investigational bridge to surgery. Patients were prospectively followed and relevant data collection was collected, including details regarding technique, clinical symptoms, complications, need for elective surgery, and overall survival.Results
Stent placement was technically successful in all but two patients (due to complete obstruction) with no procedure-related complications. Complications included stent migration (n = 4), anal pain (n = 2) and stool impaction (n = 1). Clinical success was achieved in 49 (98%) of 50 patients with resolution of bowel obstruction within 2 days of stent placement. In one patient with stool impaction 2 days after stent placement, endoscopic disimpaction was successfully performed. An elective one-stage surgical procedure was performed in all 50 patients who successfully received a SEMS as a bridge to surgery within a mean of 8 ± 2 days (range: 4-11 days) after stent placement. Mean follow-up time was 36 ± 12 months (range 3-70 months), and all patients remained alive at the time of this report.Conclusion
The newly designed SEMS placement as a bridge to surgery was a safe and effective intervention for colonic decompression in patients with acute malignant colorectal obstruction and allowed a high proportion of patients to be successfully proceeded to elective surgery. 相似文献8.
Miyayama S Matsui O Kifune K Yamashiro M Yamamoto T Kitagawa K Kasahara Y Asada Y Iida Y Miura S 《AJR. American journal of roentgenology》2000,175(6):1631-1637
OBJECTIVE: The purpose of this study was to evaluate the usefulness of self-expanding nitinol stents for palliative treatment of malignant colorectal obstruction caused by unresectable extrinsic tumor, colorectal metastasis, or peritoneal seeding. SUBJECTS AND METHODS: One covered stent and 10 uncovered stents were deployed in eight patients with colorectal obstruction due to extrinsic tumor under fluoroscopic guidance. The sites of obstruction were located in the rectum (n = 5), in the rectosigmoid colon (n = 2), and from the transverse colon to the descending colon (n = 1). Clinical usefulness and complications were analyzed. RESULTS: Stents were placed successfully in all patients. Minor modifications of the delivery system were required in the tortuous rectosigmoid and lower rectum strictures. Symptoms of obstruction were initially resolved in all but one patient. In that patient, the presence of other points of obstruction was suspected. Bowel obstruction recurred in two patients: one obstruction was due to migration of a covered stent 4 days after the procedure, and the other obstruction was due to peritoneal seeding 33 days after the procedure. Both required colostomy or ileostomy. All patients died 12-111 days after stent placement (mean, 56 days). In five patients (63%), colonic obstruction was palliated by placing a stent until the patients' death between 39 and 111 days after stent placement (mean, 62 days). Six complications occurred in four patients and included stent migration (n = 1), anal bleeding (n = 2), anal pain that required analgesia (n = 1), and fever (n = 2). CONCLUSION; This self-expandable nitinol stent adequately palliated 63% of patients with colonic obstruction due to extrinsic tumor in this small series. Patient selection is very important to the success of this treatment. 相似文献
9.
R Yi DI Gwon GY Ko HK Yoon JH Kim JH Shin KB Sung 《Acta radiologica (Stockholm, Sweden : 1987)》2012,53(7):742-749
Background Unilateral biliary metallic stent placement in the lobe with patent portal vein seemed to be a safe and effective palliative treatment of patients with contralateral portal vein occlusion caused by advanced hilar malignancy, obviating bilateral stent placement in these patients, because the hepatic lobe with portal vein occlusion ceases to produce bile due to interruption of enterohepatic circulation. Purpose To investigate the safety and efficacy of percutaneous unilateral expanded polytetrafluoroethylene (ePTFE)-covered stent placement in malignant hilar biliary obstruction with contralateral portal vein occlusion. Material and Methods From February 2008 to March 2011, 24 consecutive patients with malignant hilar biliary obstruction and unilobar portal vein occlusion were enrolled in this prospective study. All patients were treated by percutaneous placement of ePTFE-covered stents. Results Stent deployment was technically successful in all patients. Two (8%) patients experienced minor self-limiting hemobilia. No major complication was noted. Successful internal drainage was achieved in 22 (91.6%) patients. Mean serum bilirubin level, which was 12.5 mg/dl ± 8.4 before drainage, decreased significantly to 2.7 mg/dl ± 3.4, 1 month after stent placement (P < 0.001). Median survival was 191 days (95% CI, 94-288 days) and cumulative stent patency rates at 1, 3, 6, 9, and 12 months were 100%, 95%, 95%, 95%, and 71%, respectively. Two (8%) patients presented with stent occlusion due to sludge incrustation. Aside from two patients who had died within 30 days after stent placement, the other 22 patients demonstrated slight decrease in diameter of undrained lobe and did not experience cholangitis nor jaundice. Conclusion Unilateral placement of ePTFE-covered stent in the lobe with patent portal vein seems to be a safe and effective method for palliative treatment of patients with contralateral portal vein occlusion. In addition, ePTFE-covered stent placement can prevent tumor ingrowth without functional occlusion of segmental bile ducts. 相似文献
10.
Il Soo Chang Sang Woo Park Dae-Yong Hwang Moo Kyung Seong Hee-Kyung Joh So Young Yoon Yo-Han Cho Won Hyeok Choe 《Korean journal of radiology》2011,12(1):107-112
Objective
We wanted to evaluate the efficacy of stent placement using the coaxial technique with a stiff, long introducer sheath in patients with technical failure using an angiographic catheter for the obstructions proximal to the descending colon.Materials and Methods
Self-expandable metallic stent placement was attempted under fluoroscopy-guidance in 77 consecutive patients who had malignant colorectal obstruction. Stent placement was performed using an angiographic catheter and a guide wire. If the angiographic catheter could not be advanced over the guide wire into the obstructive lesions proximal to the descending colon, then a 6-Fr introducer sheath was used. The technical success rate, the clinical success rate and the complications were analyzed.Results
Successful stent placement was achieved in 75 of 77 patients (97%). The angiographic catheter failed to advance into the obstructive lesions of 11 patients (M:F = 7:4; mean age, 65.5 years) whose lesions were at the level of the splenic flexure or transverse colon. Therefore, the coaxial technique was implemented in all these 11 patients using a 6-Fr stiff introducer sheath and then the stent placement was successful. There were no complications related to the use of a stiff introducer sheath. Clinical success, which was defined as relief of clinical obstructive bowel symptoms, was obtained within 24 hours in all of patients.Conclusion
The coaxial technique using a stiff introducer sheath can increase the technical success of fluoroscopy-guided, self-expandable metallic stent placement in patients with colonic obstruction proximal to the descending colon. 相似文献11.
Palliation of Obstructing Malignant Colonic Lesions Using Self-Expanding Metal Stents: A Single-Center Experience 总被引:1,自引:1,他引:0
Shrivastava V Tariq O Tiam R Nyhsen C Marsh R 《Cardiovascular and interventional radiology》2008,31(5):931-936
To evaluate the efficacy, risks, and survival after palliative colorectal stenting at a single center, we conducted a retrospective
review of consecutive patients who had colorectal self-expanding metal stents (SEMSs) inserted over an 8-year period (September
1998 to September 2006) to relieve an obstructing colorectal tumor. All patients either had proven distant metastases or were
unfit for surgical decompression. A single interventional radiologist (R.M.) inserted the stents, which were either Memotherm
or WallFlex. Ninety-one patients with a median age of 73 years had a colorectal stent inserted for palliation of an obstructing
colorectal malignancy. Technical success was achieved in 81 of 91 (89%) patients, and clinical success in 80 of 81 (99%).
At the time of analysis (December 2006), 13 of 91 (14.2%) patients were alive. The patients who died had a median survival
of 59 days, IQR 17–181 days. Seven (7/81) patients suffered stent migration, which occurred 10.3 days (IQR, 5–14 days) after
the procedure. Three patients (3/81) re-presented with intestinal obstruction secondary to tumor ingrowth and 10 (10.9%) patients
suffered bowel perforation. Ten patients (10.9%) had two stents inserted coaxially and overlapping in one procedure. This
was performed in cases where the stricture was too long to be easily crossed by a single stent. We conclude that colorectal
SEMS is a safe and effective mode of treatment for the palliation of obstructing colorectal cancers, which avoids high-risk
surgery. 相似文献
12.
Nagata T Makutani S Uchida H Kichikawa K Maeda M Yoshioka T Anai H Sakaguchi H Yoshimura H 《Cardiovascular and interventional radiology》2007,30(5):959-967
Purpose To retrospectively clarify the utility of metallic stent placement for the treatment of the malignant obstruction of the superior
vena cava (SVC) in 71 patients with VC syndrome (SVCS) on the basis of long-term follow-up data.
Materials and Methods Seventy-one patients underwent stent placement and were followed until death. The applicability of the spiral Z-stent (S-Z-stent)
mainly used the initial and follow-up results, stent placement for bilateral BCV obstruction and the value of concurrent anticancer
therapy were studied.
Results The technical success rate was 100%, the initial clinical success rate was 87% (62/71), the primary clinical patency rate
was 88% (57/65), and the secondary clinical patency rate was 95% (62/65). The obstruction rate of the stent was 12% (8/65),
and an additional stent was useful for relief of recurrent SVCS. Survival of 57 patients in whom there was no recurrence of
SVCS until death ranged from 1 week to 29 months (mean, 5.4 months and the S-Z-stent appeared to be suitable for the treatment
of the malignant obstruction of SVC. Unilateral stent placement was effective for relief of SVCS with bilateral BCV obstruction.
Patients who received concurrent anticancer therapy survived 2 months longer than those who did not.
Conclusion Stent placement is an effective treatment for SVCS. Further, the utility of S-Z-stent for SVCS, an additional stent for recurrence,
unilateral stent for patients with bilateral BCV obstruction, and anticancer therapy after stent placement were verified. 相似文献
13.
Malignant biliary obstruction: treatment with expandable metallic stents--follow-up of 50 consecutive patients. 总被引:17,自引:0,他引:17
A consecutive series of 50 patients with malignant biliary obstruction were treated by means of palliative drainage with a metallic expandable stent. Stent placement was successful in all patients. The patients were followed up prospectively at 2-month intervals over a period of 9-22 months. Forty-one patients (82%) died; nine (18%) are still living. The overall patency and survival rates for the 50 patients were 5.8 months and 7.5 months, respectively. The 30-day mortality rate was 8% (n = 4), the minor complication rate was 18% (n = 9), and the major complication rate was 8% (n = 4). One patient (2%) had intrahepatic arterial bleeding that required embolization, one (2%) had a right subphrenic abscess, and two patients (4%) had transient septic events. Stent occlusion requiring a second intervention occurred in 24% of patients (n = 12). Excellent palliation was achieved in most patients. No stent migration occurred. No great clinical advantages in prolonged patency compared with those of other published series involving the use of plastic stents were demonstrated. Ease of placement and versatility may offset the high cost of the stent. 相似文献
14.
A. Gutzeit Ch. L. Zollikofer M. Dettling-Pizzolato N. Graf J. Largiad��r C. A. Binkert 《Cardiovascular and interventional radiology》2011,34(3):542-549
Venous stenting has been shown to effectively treat iliofemoral venous obstruction with good short- and mid-term results.
The aim of this study was to investigate long-term clinical outcome and stent patency. Twenty patients were treated with venous
stenting for benign disease at our institution between 1987 and 2005. Fifteen of 20 patients (15 female, mean age at time
of stent implantation 38 years [range 18–66]) returned for a clinical visit, a plain X-ray of the stent, and a Duplex ultrasound.
Four patients were lost to follow-up, and one patient died 277 months after stent placement although a good clinical result
was documented 267 months after stent placement. Mean follow-up after stent placement was 167.8 months (13.9 years) (range
71 (6 years) to 267 months [22 years]). No patient needed an additional venous intervention after stent implantation. No significant
difference between the circumference of the thigh on the stented side (mean 55.1 cm [range 47.0–70.0]) compared with the contralateral
thigh (mean 54.9 cm [range 47.0–70.0]) (p = 0.684) was seen. There was a nonsignificant trend toward higher flow velocities within the stent (mean 30.8 cm/s [range
10.0–48.0]) and the corresponding vein segment on the contralateral side (mean 25.2 cm/s [range 12.0–47.0]) (p = 0.065). Stent integrity was confirmed in 14 of 15 cases. Only one stent showed a fracture, as documented on x-ray, without
any impairment of flow. Venous stenting using Wallstents showed excellent long-term clinical outcome and primary patency rate. 相似文献
15.
Malignant gastroduodenal obstructions: treatment by means of a covered expandable metallic stent-initial experience 总被引:23,自引:0,他引:23
PURPOSE: To investigate the technical feasibility and clinical effectiveness of a polyurethane-covered expandable nitinol stent in the treatment of malignant gastroduodenal obstructions. MATERIALS AND METHODS: The stent was constructed in-house by weaving a single thread of 0.2-mm nitinol wire in a tubular configuration and was covered with polyurethane solution by means of a dipping method. With fluoroscopic guidance, the stent was placed in 19 consecutive patients with malignant gastric outlet obstruction (n = 15) or duodenal obstruction (n = 4). All patients had severe nausea and recurrent vomiting, and their obstructions were inoperable. RESULTS: Stent placement was technically successful in all but one patient. After stent placement, symptoms improved in all but one patient, who had another stenosis at the proximal jejunum. One patient with stent placement in the second portion of the duodenum became jaundiced. During the mean follow-up of 11 weeks, stent migration occurred in five patients 1-4 days after the procedure. All patients with stent migration were treated by means of placing a second, uncovered nitinol stent. Two of these five patients showed recurrence of stricture because of tumor ingrowth; they underwent coaxial placement of a third, covered nitinol stent with good results. CONCLUSION: Placement of a polyurethane-covered expandable nitinol stent seems to be technically feasible and effective for palliative treatment of inoperable malignant gastroduodenal obstructions. Stent migration, however, is problematic and requires further investigation. 相似文献
16.
Jun-Gong Zhao Yong-Dong Li Ying-Sheng Cheng Ming-Hua Li Ni-Wei Chen Wei-Xiong Chen Ke-Zhong Shang 《European radiology》2009,19(8):1973-1980
To prospectively evaluate the long-term clinical safety and efficacy of a newly designed self-expanding metallic stent (SEMS)
in the treatment of patients with achalasia. Seventy-five patients with achalasia were treated with a temporary SEMS with
a 30-mm diameter. The SEMSs were placed under fluoroscopic guidance and removed by gastroscopy 4–5 days after stent placement.
Follow-up data focused on dysphagia score, technique and clinical success, clinical remissions and failures, and complications
and was performed at 6 months, 1 year, and within 3 to 5 years, 5 to 8 years, 8 to 10 years, and >10 years postoperatively.
Stent placement was technically successful in all patients. Complications included stent migration (n = 4, 5.33%), chest pain
(n = 28, 38.7%), reflux (n = 15, 20%), and bleeding (n = 9, 12%). No perforation or 30-day mortality occurred. Clinical success
was achieved in all patients 1 month after stent removal. The overall remission rates at 6 months, 1, 1–3, 3–5, 5–8, 8–10,
and >10 year follow-up periods were 100%, 96%, 93.9%, 90.9%, 100%, 100%, and 83.3%, respectively. Stent treatment failed in
six patients, and the overall remission rate in our series was 92%. The median and mean primary patencies were 2.8 ± 0.28 years
(95% CI: 2.25–3.35) and 4.28 ± 0.40 years (95% CI: 3.51–5.05), respectively. The use of temporary SEMSs with 30-mm diameter
proved to be a safe and effective approach for managing achalasia with a long-term satisfactory clinical remission rate.
Supported by the National Key Medical Research and Development Program of China during the 9th Five-year Plan Period (no.
96–907–03–04), Shanghai Nature Science Funds (no. 02Z1314073), Shanghai Medical Development Funds (no. 00419), the National
Natural Science Foundation of China (no. 30670614). 相似文献
17.
Yang ZQ Song HY Kim JH Shin JH Kim TW Yook JH Kim BS 《Journal of vascular and interventional radiology : JVIR》2007,18(12):1533-1537
PURPOSE: To assess the technical feasibility and clinical effectiveness of covered stent placement in patients with recurrent malignant obstructions after Billroth I reconstruction. MATERIALS AND METHODS: From June 1997 to November 2005, 16 patients underwent covered stent placement for recurrent gastric cancer after Billroth I reconstruction. A total of 19 covered stents were used, including 14 dual stents and five fully covered stents, as available. RESULTS: Stent placement was technically successful in all patients, with 13 of 16 patients (81%) showing improvement of symptoms. Stent migration occurred in one patient, tumor ingrowth in one, and stent collapse and/or bowel perforation in one. Nine patients (56%) had concomitant (n=7) or subsequent (n=2) biliary obstruction. One patient was lost to follow-up. The remaining 15 patients died 5-628 days (median, 52 days; mean, 120 days) after stent placement due to progression of disease or pneumonia. CONCLUSIONS: Placement of covered metallic stents is feasible and effective in patients with recurrent malignant obstruction after Billroth I reconstruction. 相似文献
18.
目的 比较胆道支架跨与不跨十二指肠壶腹部放置治疗低位恶性梗阻性黄疸患者的临床预后差异.方法 分析本院符合条件的56例恶性梗阻性黄疸患者的临床资料,其中支架跨十二指肠壶腹部放置31例,支架不跨十二指肠壶腹部放置25例,比较2组患者间支架置入术后4~7 d总胆红素下降率、胆道感染率及支架再阻塞率等方面的差异.结果 跨壶腹部组与不跨壶腹部组的生存期分别为(180.3±142.5) d、(178.6±137.7) d(P=0.840).2组患者术后4~7 d总胆红素下降率为42.0%±43.6%、41.4%±28.7%(P=0.950);治疗成功率分别为93.5%、92.0%(P=1.0).跨壶腹部组术后胆道感染7例(22.6%),不跨壶腹部组术后胆道感染5例(20.0%)(P=0.815).2组患者支架再阻塞率分别为22.6%、28.0%(P=0.642).结论 2种支架置入方式均是治疗低位胆道梗阻安全、有效的方法;与支架非跨壶腹部放置相比,支架跨壶腹部放置未增加胆道感染及支架再狭窄发生率. 相似文献
19.
Separate支架在治疗胃十二指肠恶性梗阻中的应用 总被引:2,自引:1,他引:1
目的 探讨Separate支架置入术在姑息性治疗不能手术的胃肠道恶性梗阻的可行性和有效性。方法 34例患者采用经口置入Separate支架治疗不能手术的恶性胃十二指肠梗阻。梗阻的原因分别是胃癌11例、胰腺癌12例、转移性肿瘤3例、胆道肿瘤6例和十二指肠癌2例。透视下分别将Separate支架的外层带膜支架和内层裸支架同轴重叠释放在狭窄病变处。结果 技术成功率为97%,未发生严重并发症。33例患者胃肠道梗阻症状缓解或消失,在Separate支架置入后,患者进食能力评分平均从3.8提高到1.2。随访期间未发现支架移位和肿瘤内生性生长等并发症,l例患者由于肿瘤浸润致支架近端梗阻复发,置入第2枚支架。结论 经口途径置入Separate支架姑息性治疗不能手术的胃十二指肠恶性梗阻是可行的和有效的。 相似文献
20.
Gutzeit A Binkert CA Schoch E Sautter T Jost R Zollikofer CL 《Cardiovascular and interventional radiology》2009,32(1):97-105
Purpose: To retrospectively evaluate the clinical effectiveness of a self-expanding uncovered Wallstent in patients with malignant
gastroduodenal obstruction. Materials and Methods: Under combined endoscopic and fluoroscopic guidance, 29 patients with a malignant gastroduodenal stenosis were treated with
a self-expanding uncovered metallic Wallstent. A dysphagia score was assessed before and after the intervention to measure
the success of this palliative therapy. The dysphagia score ranged between grade 0 to grade 4: grade 0 = able to tolerate
solid food, grade 1 = able to tolerate soft food, grade 2 = able to tolerate thick liquids, grade 3 = able to tolerate water
or clear fluids, and grade 4 = unable to tolerate anything perorally. Stent patency and patients survival rates were calculated.
Results: The insertion of the gastroduodenal stent was technically successful in 28 patients (96.5%). After stenting, 25 patients
(86.2%) showed clinical improvement by at least one score point. During follow-up, 22 (78.5%) of 28 patients showed no stent
occlusion until death and did not have to undergo any further intervention. In six patients (20.6%), all of whom were treated
with secondary stent insertions, occlusion with tumor ingrowth and/or overgrowth was observed after the intervention. The
median period of primary stent patency in our study was 240 days. Conclusion: Placement of an uncovered Wallstent is clinically effective in patients with malignant gastroduodenal obstruction. Stent
placement is associated with high technical success, good palliation effect, and high durability of stent function. 相似文献