Prevalence of intestinal parasitic infections in Riyadh district, Saudi Arabia

A total of 23,516 stool specimens collected from patients attending three medical centres in Riyadh, Saudi Arabia, were examined for intestinal parasites. Of these 5737 (24.4%) were positive. Entamoeba histolytica (8.8%) and Giardia lamblia (6.3%) were the commonest parasites found, and in the age group of one to 15 years. Giardia was found in 14.8% of males and 11.9% of females. Other intestinal parasites present included Ascaris lumbricoides, Trichuris trichiura, Schistosoma mansoni, Hymeolepis nana. Ancylostoma duodenale, Enterobius vermicularis. Taenia saginata and Schistosoma hematotium.     

Clostridium difficile-associated disease among patients in Dhahran, Saudi Arabia

Clostridium difficile-associated diarrhea (CDAD) is an important healthcare-associated infection. However, there are no data from Saudi Arabia on this disease. A two-year prospective, observational study on the incidence of CDAD in a hospital in Saudi Arabia was carried out. Stool analysis for C. difficile toxins A and B was carried out by an enzyme-linked immunosorbent assay. Medical and laboratory records were reviewed. Of the total number of patients, there were 53.3% male and the mean age was 44.6 ± 27.2 years. Of the 913 specimens, only 42 (4.6%) were positive for C. difficile toxins. The annual incidence rates of C. difficile were 1.2 and 0.9 per 1000 discharges, and 2.4 and 1.7 per 10,000 patient days in 2007 and 2008, respectively. Of the total number of cases, 52.4% were with onset in the hospital, 38.1% were with onset in the community and 9.5% were community-onset but healthcare facility-associated CDAD. Of the cases, 16 (39%) patients did not have exposure to antimicrobial drugs in the 3 months prior to the test date. The remaining patients received antimicrobial drug therapy. Cephalosporin and fluoroquinolone were the most common antimicrobial drugs used. Overall, the prevalence of C. difficile-associated diarrhea was low; further studies are required in Saudi Arabia to elucidate the true prevalence of the disease.     

Prevalence of bleeding symptoms among young adults in Saudi Arabia,a national survey

Prevalence of bleeding disorders vary due to several factors including geographical location. Mild bleeding disorders can lead to iron deficiency, morbidity, and in severe cases mortality. Quantification of haemorrhagic symptoms is a key component in management of bleeding disorders and a challenging task for clinicians.An abridged version of MCMDM-1vWD questionnaire with validated Arabic translation was used to quantify bleeding disorders in adult students (n = 1138) in 4 different regions of Kingdom of Saudi Arabia. Statistical analysis was performed to indicate gender disparity and prevalence.74.5% of respondents answered at least 1 question with affirmation, with 32.3% affected in Riyadh showing the highest prevalence and 14.03% affected in Dammam showing the least prevalence (P-value < .001). Gender-wise, higher prevalence of bleeding disorders in females 54.9% than in males 45.1% was observed (P-value .01). Epistaxis prevalence was significantly higher in males 30.7% vs 23.2% in females (P-value .0004), while cutaneous symptoms were reported significantly more by female participants 29.7% vs 12.3% in males (P-value < .001). Menorrhagia was reported by 28% of females, with heavy bleeding experienced by 57.6% female participants for <7 days while in 42.4% of females for >7 days.The current study signifies the ethnic distribution and gender disparity of mild bleeding disorders, and highlights the need for national surveillance system in order to improve management of patients with bleeding disorders.     

Sexually transmitted infections in Saudi Arabia

Background  

Data on sexually transmitted infections (STIs) in Saudi Arabia (SA) and other Islamic countries are limited. This study describes the results of a five-year surveillance for STIs in SA.     

Acute respiratory tract infections among Hajj medical mission personnel, Saudi Arabia.

OBJECTIVES: To estimate the prevalence of acute respiratory tract infections (ARI) among 250 personnel serving in a Hajj medical mission, Al-Hada and Taif Armed Forces Hospitals, during the 2005 season and to determine the effectiveness of protective measures, including influenza vaccination, for these infections. METHODS: This was a nested case-control study. A questionnaire was distributed to the study cohort two weeks after the Hajj period and was self-administered by all recruited subjects. In addition, the medical records of study subjects were reviewed at Al-Hada Hospital for the same period in order to document ARI. RESULTS: The attack rate for ARI among study subjects during Hajj season or within two weeks of returning was 25.6% (64/250). Logistic regression analysis of factors related to acquiring ARI revealed that contact with pilgrims imposed an extremely high risk of infection (adjusted OR 13.2, 95% CI 1.5-117.6). Moreover, non-use of alcohol-based hand disinfection carried a more than 8-fold risk of acquiring ARI compared to those who always used alcohol for hand disinfection (adjusted OR 8.4, 95% CI 2.2-32.2). Smoking was also a predictor of ARI in our cohort and influenza vaccination was associated with a 30% reduction in ARI compared to unvaccinated subjects, although this finding was not statistically significant. Unexpectedly, the logistic regression model showed that Saudi nationals were three times more likely to acquire ARI than non-Saudis (adjusted OR 3.1, 95% CI 1.2-8.4). CONCLUSIONS: The common practice among pilgrims and medical personnel of using surgical facemasks to protect themselves against ARI should be discontinued and regular use of alcohol-based hand scrubs should be more vigorously encouraged. Further research is needed to evaluate the protective value of N95 facemasks against ARI during the Hajj period.     

Prevalence of radiographic knee osteoarthritis in Saudi Arabia

In this cross-sectional study we looked at the radiographic evidence of osteoarthritis (OA) of the knee in 300 randomly chosen patients attending 14 primary care facilities for different medical conditions. Radiographic OA was seen in 89 out of 167 males (53.3%) and in 81 out of 133 females (60.9%). The patella was involved with radiographic osteoarthritic changes in 80.7% and 87.8% of female and male OA patients, respectively. In most cases the medial compartment joint space was narrowed. Radiographic OA of the knee is very common in Saudi patients, especially in the patellofemoral compartment. Received: 18 April 2001 / Accepted: 10 September 2001     

Prevalence of impaired awareness of hypoglycemia and its risk factors among patients with type 1 diabetes in Saudi Arabia

Background and aimsTo determine the prevalence of impaired awareness of hypoglycemia (IHA) and self-identification of symptoms in patients with type 1 diabetes (T1D).MethodsA cross-sectional study was conducted on 242 patients with T1D at the Diabetes Treatment Center, Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia from May 2021 to September 2021. In addition to the demographic data, patients' HbA1c level was also collected. Awareness and symptoms of hypoglycemia were assessed using two validated questionnaire-based methods, namely the Gold and Edinburgh methods.ResultsThe prevalence of IAH among patients with T1D was 62.8% and the presence of IAH was significantly associated with the duration of T1D (p = 0.019). Compared to males, females had significantly higher (p < 0.05) levels of warmth, pounding heart, and inability to concentrate. Compared to unmarried, married patients had significantly higher levels of (p < 0.05) drowsiness, dizziness, and blurred vision. Similarly, compared to school educated, college-educated showed a higher hunger level (p < 0.05). Patients with HbA1c ≥ 7% possess a significantly higher level of drowsiness, dizziness, and hunger. Dizziness, warmth, difficulty speaking, pounding heart, and blurred vision were significantly higher among patients with diabetes duration ≥10 yrs. Nausea was significantly higher among smokers than non-smokers (p < 0.05).ConclusionThe prevalence of IAH is high among patients with T1D in Saudi Arabia. Focused and evidence-based interventions are essential to minimize the hypoglycemia risk among patients with T1D.     

Lead poisoning among children in Saudi Arabia

Six Saudi children aged between 10 and 30 months were found to have lead poisoning. Two of them presented with encephalopathy. Twenty children with unexplained convulsions, some of whom died, were reported to have been admitted to the local district hospital recently. All our cases were diagnosed within 2 weeks of diagnosing the index case. The source of lead was found to be a locally used teething powder known as 'Saoott' and 'Cebagin'. This was prescribed by a traditional healer. The lead content of this powder was found to be 51%. Chemical analysis of other locally used eye cosmetics and teething medicines showed a lead content of up to 88%. The difficulties faced in diagnosis and managements of these cases in developing countries are discussed. The importance of prevention is stressed.     

Prevalence of Celiac Disease among Symptom-free Children from The Eastern Province of Saudi Arabia

Background/Aim:Epidemiological studies of celiac disease (CD) among Saudi children have been performed only within some groups who are at a high risk of developing CD. The aim of this study was to determine the prevalence of CD among symptom-free children from the public schools of the military campus of National Guard in the Eastern Province of Saudi Arabia.Results:Of the 1141 participants, 32 were IgA-tTG positive. Thus, the estimated serology-positive prevalence was 3%. An intestinal biopsy was performed in 10 of the participants with antibody positivity. The biopsy findings of all 10 children were consistent with CD. Thus, the estimated biopsy-confirmed prevalence was about 1%.Conclusions:The prevalence of CD was estimated to be about 1% among symptom-free children from the public schools of the military campus of National Guard in the Eastern Province of Saudi Arabia.     

Prevalence of seromarkers of HBV and HCV among blood donors in eastern Saudi Arabia, 1998-2001

The prevalence of serological markers of HBV and HCV were determined for blood donors in eastern Saudi Arabia. Between 1998 and 2001, 13,443 donors (10,778 Saudi and 2665 non-Saudi), were screened for HBsAg, anti-HBc Ab, and anti-HCV Ab using commercial kits. There was a steady decrease in the HBsAg (2.58 and 1.67%), anti-HBc rates (15.32 and 9.15%), and anti-HCV (1.04 and 0.59%) rates between 1998 and 2001, respectively. However, there was a marked difference between Saudi and non-Saudi donors with regard to anti-HBc (P < 0.001) and anti-HCV (P < 0.01), but not HBsAg prevalence rates in the same time period.     

Predictors of diabetes foot complications among patients with diabetes in Saudi Arabia

AimsTo identify risk factors and clinical biomarkers of prevalent diabetes foot complications, including foot ulcers, gangrene and amputations among patients with diabetes in Jeddah, Saudi Arabia.Methods598 diabetes patients from Jeddah participated in the current study. Patients were considered to have diabetes foot complications if they reported diagnosis of foot ulcers or gangrene or amputations in a questionnaire administered by a physician and confirmed by clinical exams. Information on socio-demographic and lifestyle variables was self-reported by patients, and several clinical markers were assessed following standard procedures.ResultsThe prevalence of diabetes foot complications in this population was 11.4%. In the multivariable model without adjustment for PAD (peripheral artery disease) and DPN (diabetes peripheral neuropathy), non-Saudi nationality, longer diabetes duration and insulin use was significantly associated with higher diabetes foot complications prevalence. Each 1 g/L increase of hemoglobin was associated with 2.8% lower prevalence of diabetes foot complications. In the multivariable model adjusting for PAD and DPN, the previously observed associations except for nationality were no longer significant. Patients with both DPN and PAD had 9.73 times the odds of diabetes foot complications compared to the patients with neither condition.ConclusionIn this population, longer diabetes duration, insulin use, lower hemoglobin levels and non-Saudi nationality were associated with higher prevalence of foot complications. These associations were largely explained by the presence of DPN and PAD except for non-Saudi nationality. Diabetes patients with both DPN and PAD had nearly 10-fold increased risk of foot complications than those with neither condition.     

Prevalence of radiographic osteoarthritis of the hands in Saudi Arabia

We studied the radiographic evidence of osteoarthritis (OA) of the hands in 300 patients (167 male, 133 female) attending 14 primary care facilities for a variety of medical conditions. Radiographic OA was seen in 30.3% of males and 36.3% of females. Most commonly affected were the metacarpophalangeal joints, followed by the distal interphalangeal and carpometacarpophalangeal joints.     

Correlates of memory loss and depression among myocardial infarction patients in Al-Qassim,Saudi Arabia

Background

After myocardial infarction (MI), patients have an elevated risk for depression, which has a negative impact on morbidity and mortality for patients. As depression and memory function are associated, we examined them in the context of one another. Our objectives were to determine the proportion of patients with either depression only, memory loss only, or both depression and memory loss and to examine the correlates with each outcome.

Prevalence of intestinal parasites among members of the public in Kuala Lumpur, Malaysia

A total of 246 stool samples were collected from the public who participated in a Medical Fair held at the University Malaya Medical Center. The stools were examined for intestinal parasites using the formalin-ether concentration technique. The overall infection rate was 6.9% (17 out of 246), with Trichuris trichiura being the most common parasite (4.5%), followed by Ascaris lumbricoides (0.8%), Clonorchis sinensis (0.8%), hookworm (0.4%), and Entamoeba histolytica (0.4%). None of these participants showed any clinical symptoms. The highest infection rate was among the Chinese 7.7% (13 out of 169), followed by the Malays 7.0% (3 out of 43) and Indians 3.3% (1 out of 30). The highest infection rate was in the age group 16-30 years, which was 9% (6 out of 67). The two cases of clonorchiasis were from two Chinese women aged 28 and 66 years. The 28-year-old Chinese woman was born in Malaysia and had never left the country, while the older woman was also born in Malaysia but had visited Hong Kong as a tourist on two occasions. Both enjoyed eating raw fresh water fish with porridge.     

Prevalence and socioeconomic risk factors of obesity among urban female students in Al-Khobar city, Eastern Saudi Arabia, 2003

The aim of this study was to determine the prevalence and the socioeconomic risk factors associated with obesity among female school-aged children and adolescents in primary and intermediate schools in Al-Khobar city, Kingdom of Saudi Arabia. This is a cross-sectional study conducted in Al-Khobar city, which is located in the eastern part of Saudi Arabia, during the period of January to March 2003. It involved 2239 female schoolchildren randomly selected from 30 regular government and private primary and preparatory schools. The students' ages ranged from 6 to 17 years, with a mean of 10.49 +/- 2.64 years. A multistage stratified random sampling technique with proportional allocation was used. Data were collected using questionnaires and anthropometric measurements. Body mass index interpretation was based on using a table of standard definitions for overweight and obesity in children (Cole's). The spss version 10 (SPSS Inc., Chicago, IL, USA) was used for data entry and analysis. A chi-squared test was used in cross-tabulation analysis to test the significance of association between body mass index and socioeconomic variables. The prevalence of overweight and obesity were 20% and 11%, respectively. The prevalence of overweight was higher among schoolchildren with father in private work (P<0.01) and the prevalence of overweight and obesity was higher among schoolchildren with highly educated mothers (P=0.008). The prevalence of overweight and obesity among female school-aged children and adolescents in the Al-Khobar city was very high. Accordingly, it is recommended that health education programmes regarding obesity should be provided to all schoolchildren, their families and teachers.     

Hepatitis B virus among saudi children in Gizan,Saudi Arabia

Summary Using the enzyme-linked immunosorbent assay (ELISA), the prevalence rates for hepatitis B virus surface antigen (HBsAg), antibody to core antigen (anti-HBc), and antibody to surface antigen (anti-HBs) were studied among 325 school children and those seeking treatment for minor ailments in Gizan City, Saudi Arabia. Tests for hepatitis B virus e antigen (HBeAg), antibody to HBeAg (anti-HBe), IgM antibody to HBV core antigen (IgM anti-HBc) and antibody to delta-virus were made in HBsAg carriers. There was a serological evidence of HBV infection in 91 (28%) Saudis of which 11.1% were HBsAg carriers, 9.5% positive for anti-HBs and 7.4% positive only for anti-HBc. There was no intersex difference for positivity for HBsAg, anti-HBs and anti-HBc. The evidence of existing or earlier infection was higher in females. Among HBsAg carriers, none of the 24 was positive for IgM anti-HBc, 12% were positive for HBeAg or anti-HBe. Anti-delta antibody was present in one of the nine carriers tested. HBV infection in Gizan City is acquired fairly early during childhood with little clinical evidence suggestive of an acute hepatitis. Immunization against HBV should be considered in the neonatal period to prevent the long term sequelae of HBV, like cirrhosis and primary hepatocellular carcinoma.

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Hepatitis B-Virus-Marker bei Kindern in Gizan, Saudi-Arabien

Zusammenfassung Bei 325 Schulkindern und Kindern, die wegen geringfügiger Beschwerden in Gizan, Saudi-Arabien, zur Behandlung kamen, wurden Untersuchungen zur Prävalenz des Hepatitis B-Virus-Oberflächenantigens (HBsAg), des Antikörpers gegen core-Antigen (anti-HBc) und des Antikörpers gegen Oberflächenantigen (anti-HBs) unter Verwendung des enzymgebundenen Immunsorbent-Tests (ELISA) vorgenommen. Bei Trägern von HBsAg wurden auch Tests zur Bestimmung des Hepatitis B Virus e-Antigen (HBeAg), des Antikörpers gegen HBeAg (anti-HBe), des IgM-Antikörpers gegen HBV core-Antigen (IgM anti-HBc) und des Antikörpers gegen delta-Virus durchgeführt. Bei 91 Saudis (28%) ergab sich ein serologischer Beweis für eine HBV-Infektion, 11,1% davon waren HBsAg-Träger, 9,5% anti-HBs-positiv und 7,4% nur anti-HBc-positiv. Es zeigten sich keine Geschlechtsunterschiede in der Positivität für HBsAg, anti-HBs und anti-HBc. Anhalt für eine vorliegende oder früher durchgemachte Infektion bestand bei Mädchen häufiger als bei Knaben. Von den 24 HBsAg-Trägern war keiner anti-HBc-IgM-positiv, bei 12% wurden sowohl HBeAg wie anti-HBe nachgewiesen. Bei einem der neun untersuchten Träger fanden sich Anti-delta-Antikörper. Die HBV-Infektion in der Stadt Gizan wird relativ früh in der Kindheit erworben, wobei nur geringfügige klinische Zeichen für eine akute Hepatitis auftreten. Es sollte eine Immunisierung gegen HBV in der Neonatalperiode erwogen werden, um die Langzeitfolgen der HBV-Infektion wie Leberzirrhose und hepatozelluläres Karzinom zu verhüten.

     

Determinants of asthma control among children in Saudi Arabia

Objective: Asthma is the most common chronic disease among children. Uncontrolled asthma may considerably decrease the quality of life for patients and their families. Our objective was to identify possible risk factors for poor asthma control in children. Methods: A cross-sectional study was conducted among children with asthma aged 4–11?years who attended a pediatric clinic for follow-up visits at one of the major teaching hospitals in Riyadh, Saudi Arabia. Asthma control status was measured by the childhood asthma control test. Multiple logistic regression analysis was performed to explore the relationships between the outcome and exposure variables. Results: Uncontrolled asthma was present in 89 out of 158 children (59.3%). Asthma control improved with the number of siblings. Control improved by 69% with two or three siblings (OR?=?0.31, 95% CI?=?0.10–0.96) and by 87% with four or more siblings (OR?=?0.13, 95% CI?=?0.04–0.48). Similarly, asthma control improved with an increased asthma knowledge of the caregiver (OR?=?0.87, 95% CI?=?0.81–0.93). Household incomes less than SAR 15?000 and sharing a bedroom increased the odds of having uncontrolled asthma by 2.30 (95% CI?=?1.02–5.21) and 3.33 (95% CI?=?1.33–8.35), respectively. Conclusions: In addition to knowledge, socioeconomic factors, such as family income, household crowding, and the number of siblings are associated with asthma control among children in Saudi Arabia. Further research is needed to investigate the role of these factors.