结构化运动锻炼疗法对多囊卵巢综合征的疗效研究进展

多囊卵巢综合征（PCOS）是育龄期女性最常见的内分泌性疾病.该综合征的临床特征是月经失调、不孕、肥胖、多毛等,其病因目前尚不明确.PCOS 也是育龄期女性不孕的最常见原因之一,不孕常常成为患者就诊的主诉.针对PCOS患者的药物治疗包括改善胰岛素抵抗、调节月经周期、促排卵等,常用药物有二甲双胍、克罗米芬等,但是近年研究发现,药物治疗并不能完全缓解患者病情、改善生育功能[1].新近有研究发现,结构化运动锻炼疗法（SET）可以有效减轻PCOS 患者体重、改善胰岛素抵抗、恢复正常月经,本文就近年关于SET 和PCOS 的临床研究作一综述.     

多囊卵巢综合征的中西医结合治疗进展

多囊卵巢综合征(PCOS)是妇科常见的一种生殖内分泌疾病,严重影响患者的生活质量。目前PCOS西医病机尚未明确,病因错综复杂,临床上多使用避孕药、促排卵药及降糖药等药物治疗,取得不错的疗效。中医认为PCOS病机主要为肝、脾、肾三脏功能失调,加之痰浊血瘀,治疗原则围绕疏肝、补脾、益肾,兼以化痰、祛瘀,根据患者的临床症状及表现辨证施治,效果显著。本文就PCOS的中西医结合治疗进展进行阐述,以期为临床治疗PCOS提供可靠、有效的参考。     

达英-35治疗多囊卵巢综合征30例临床观察

多囊卵巢综合症(Polycystic Ovary Syndrme,PCOS)是一种好发于青春期及育龄妇女的内分泌紊乱综合症,发病原因至今尚不明确,表现为月经失调、多毛和肥胖等征像,以高雄激素血症和高胰岛素血症为特征.目前临床上治疗PCOS以药物为主,但现尚无规范的治疗标准,如何提高疗效.     

达英_(-35)治疗多囊卵巢综合征的临床分析

多囊卵巢综合征(PCOS)是由多种神经内分泌和代谢性疾病引起的卵巢终期病变。近期引起慢性无排卵、月经失调、不孕、多毛、痤疮、肥胖和黑棘皮症等,B超见卵巢体积增大,卵泡数目增多,激素水平异常。远期引起子宫内膜癌、糖尿病和心血管疾病。PCOS的治疗原则是促进排卵,恢复正常月     

多囊卵巢综合征的中医治疗现状

多囊卵巢综合征（polycystic ovary syndrome，PCOS）是妇科常见的生殖功能障碍性疾病，是因月经调节机制失调所产生的一种综合征，在妇科内分泌临床上占20％～60％。主要表现为月经失调、排卵障碍、多毛、痤疮、肥胖、不孕，其内分泌紊乱包括高LH／FSH比值、高雄激素血症、高泌乳素血症、高胰岛素及胰岛素抵抗等。中医在临床治疗取得了可喜的成绩，现就近年中医治疗PCOS的研究进展综述如下。     

二甲双胍治疗多囊卵巢综合征的研究进展

多囊卵巢综合征(PCOS)是一种发病多因性、临床表现呈多态性的育龄妇女常见的内分泌及代谢异常性疾病,也是不孕不育的主要原因之一,以月经失调、排卵障碍、雄激素过多、高胰岛素和胰岛素抵抗为主要特征。二甲双胍作为胰岛素增敏剂,可改善患者对胰岛素的抵抗,并能够起到积极的治疗作用。笔者对二甲双胍在治疗PCOS的研究进展进行综述。     

多囊卵巢综合征73例育龄期妇女生殖内分泌状态的探讨

目的探讨多囊卵巢综合征(PCOS)妇女在育龄期的生殖内分泌状态.方法选择73例育龄期PCOS妇女,分为月经稀发组(42例)和继发闭经组(31例),以月经周期正常、BBT双向,因男方因素不孕就诊的育龄期妇女39例为对照组,采用酶联免疫法(ELISA法)测定其血清生殖激素,并进行分析对比.结果 PCOS育龄妇女的血清T、LH水平、LH/FSH比值显著高于对照组(P＜0.01、P＜0.05、P＜0.01)月经稀发组的T、E2平均值高于继发闭经组(P＜0.05).结论育龄期PCOS妇女拥有较高的血清T、LH水平和高LH/FSH比值,且表现为月经稀发的PCOS妇女在育龄期有更严重的内分泌代谢失调,并伴有较低的妊娠率.     

多囊卵巢综合征和心血管并发症

<正>多囊卵巢综合征(PCOS)是育龄妇女常见的内分泌紊乱性疾病,其病理生理改变范围广泛,涉及神经内分泌、糖代谢、卵巢调控因素异常。育龄妇女中PCOS的患病率占5%～10%,近几年来对PCOS中神经内分泌代谢紊乱日益增多的研究及其对妇女生活质量的长远影响的报道,使人们对PCOS的治疗观念已不仅仅限于促排卵和妊娠,PCOS的结局已超出了生殖范畴,PCOS并发症己被纳入了PCOS研究的新视野且其重要性日益突出。     

多囊卵巢综合征患者胰岛素抵抗与血清激素水平的研究

<正>多囊卵巢综合征(PCOS)是育龄妇女中最常见的内分泌紊乱性疾病。目前的研究认为,胰岛素抵抗(IR)是导致PCOS在代谢紊乱和生殖内分泌功能失调的主要原因。在PCOS患者中,50%～70%的患者有IR[1]。肥胖是PCOS患者中较常见的临床表征,也是加IR和PCOS不育的一个重要因素。本文通过对PCOS患者肥胖组与非肥胖组内分     

多囊卵巢综合征不孕育龄女性的心理特征与运动干预研究进展

多囊卵巢综合征(PCOS)是一种常见的内分泌疾病,临床表现为肥胖、多毛及身体不适,导致育龄女性出现月经稀少、生育能力下降,严重者甚至不孕不育,治疗过程中会引起焦虑、抑郁、夫妻关系不和等心理社会问题。特别是PCOS育龄女性在不孕治疗过程中存在更多的心理问题,而运动是有效解决PCOS不孕育龄女性心理问题的非药物治疗方法。本文就PCOS不孕育龄女性的心理特征与运动干预研究进展进行综述,为临床治疗提供参考。     

Degraded and undegraded carrageenans and experimental gastric and duodenal ulceration

The prevention of histamine-induced gastric and duodenal ulceration in the guinea-pig has been examined using a series of undegraded and degraded carrageenans. Undegraded carrageenans were active at lower doses than degraded carrageenans. The high viscosity of the undegraded carrageenans in solution prevented their use in larger doses. Degradation of carrageenan without serious loss of sulphate, gives a product which allows the dose to be increased to an extent that its effect more than offsets the slight loss in activity caused by the degradation. No single feature of carrageenan structure can be related to anti-ulcer activity although degradation, and hence reduction of molecular size, generally reduces activity. Sulphate contents over 30% have little apparent effect on activity; κ-carrageenans were not consistently different in anti-ulcer activity from Λ-carrageenans. This contrasts with the antipeptic activity of carrageenans where κ-carrageenans are less active than their Λ-counter-parts. As with antipeptic activity, the degree of anti-ulcer activity is probably determined by a combination of structural features which includes molecular size and polyanionic properties.     

Affective and Anxiety Disorders and Alcohol and Drug Dependence:

Depression and anxiety frequently coexist in patients with substance use disorders. This clinically-oriented article examiens the relationship between these conditions and emphasizes data showing that substances of abuse can cause signs and symptoms of both depression and anxiety. These substance-related syndromes appear to have a different course and prognosis than uncomplicated, independent anxiety and major depressive disorders, and clinicians should consider the role of alcohol and other drugs in all patients presenting with these complaints. The authors will also outline an approach for diagnosing and managing patients with the combination of a substance use and depressive or anxiety disorder.     

Alcohol and Substance Use and Abuse in Women and Children

No abstract available for this article.     

Glucosidase and fucosidase inhibitors and Advances in nucleosides and nucleotides.

The American Chemical Society Symposium "Glucosidase and fucosidase inhibitors" took place on 1 April 1998 and was organized by Professors Zbigniew J Witczak (UConn, School of Pharmacy, CT, USA), Kuniaki Tatsuta (Waseda University, Tokyo, Japan) and Waldemar Priebe, MD (Anderson Cancer Center, University of Texas, USA). Professor Witczak provided introductory remarks including the status of existing glucosidase inhibitors, and chaired the morning session, which consisted of six lectures. The symposium was well received, and was particularly attractive for those interested in networking, as attendance was about sixty. In addition, some participants and attendees presented posters on the subject during the regular poster session organized by the Division of Carbohydrate Chemistry.