241例孕妇血清中人微小病毒B19—IgM与其他TORCH抗体检测结…

本文报告２４１例孕妇血清中人微小病毒Ｂ１９－ＩｇＭ及其他ＴＯＲＣＨ抗体的检测结果，其中Ｂ１９－ＩｇＭ阳性率为７．０５％，与蓁四项抗体阳性率比较，均呈显著性差异，表明我地区孕妇中人微小病毒Ｂ１９较其余四项ＴＯＲＣＨ因子有着较高的新近感染率，从而提示有必要将Ｂ１９－ＩｇＭ列为孕发ＴＯＲＣＨ监测项目之一。     

105例上感及皮疹孕妇和正常孕妇血清中人微小病毒B19抗体检测结果分析

作者用ＥＬＩＳＡ法检测了１０５例有上感及皮疹史孕妇和正常孕妇血清中的Ｂ１９特异性抗体，其结果Ｂ１９－ＩｇＧ抗体的总阳性率为３３．３％（３５／１０５），表明在我地区存在着Ｂ１９感染孕妇和Ｂ１９易感孕妇（Ｂ１９－ＩｇＧ抗体阴性者）；同时检测的Ｂ１９－ＩｇＭ抗体的阳性率为：有上感及皮疹史者是１２．９％（９／７０），正常孕妇均为阴性（０／３５），两者有显著性差异（Ｐ＜０．０５），提示上感及皮疹与Ｂ１９的新近感染相关，而孕期的Ｂ１９新近感染可致胎儿水肿死亡。因而我们认为孕期作该病毒监测在保证优生工作中有着重要意义。     

孕妇人微小病毒B19-IgM与城乡和季节的关系

用ELISA法检测了 4 93例孕妇之人微小病毒B19-IgM ,其中城市孕妇为 2 31例 ,阳性率 6 % ,农村孕妇为 2 6 2例 ,阳性率 0 7% ,两者有极显著差异 (P <0 0 1) ,显示城市孕妇更易感染B19病毒 ;冬春孕妇为 2 5 0人 ,阳性率 5 2 % ,夏秋为2 4 3例 ,阳性率为 1 2 % ,两者也相差显著 (0 0 1

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Prevalence of human parvovirus (B19) and rubella virus infections in urban and remote rural areas in northern Brazil

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Conclusions: A high level of B19 DNAemia was associated with symptomatic infection, with severe anemia, whereas low-level DNAemia was long-lasting in asymptomatic subjects with impaired immunologic responses. The endpoint titration assay by nested PCR was very useful for the monitoring of B19 infection, particularly following the therapeutic intravenous immunoglobulin administration.     

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The effect of combined therapy with ritodrine,erythromycin and verapamil on the frequency of micronuclei in peripheral blood lymphocytes of pregnant women

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