儿童人工晶体二期植入术

目的确定后房型人工晶体二期植入术矫正儿童无晶体眼的视力预后及手术适应证。方法对３４只儿童术后无晶体眼，在分离虹膜与后囊膜的粘连，形成足够的人工晶体植入放置空间后，根据后囊膜的完整与否，采用不同的技术二期植入后房型人工晶体。结果术后随访６～２４个月，２９只眼（８５．２９％）术后矫正视力等于或高于术前最佳矫正视力，１６只眼（４７．０６％）未矫正视力≥０．５，２８只眼（８２．３５％）矫正视力≥０．５。结论对于尚存完整或部分后囊膜的儿童无晶体眼，后房型人工晶体二期植入术是安全、有效的矫正方法。     

无后囊的后房型人工晶体缝线固定术

本文报告３０例（３０只眼）的后房型人工晶体缝线固定植入术，平均年龄４３．５岁。１７只眼为白内障囊内摘除术后，５只眼为囊外摘除破后囊膜者，８只眼为外伤白内障。术后随访３－１８个月，矫正视力≥０．５者为２６只眼（８６．６％），比术前矫正视力略有（０．１６）。手术中并发症主要有前房出血，瞳孔变开豚玻璃体混浊加重。术后炎性反应较一般后房人工晶体植入术重。我们对手术探讨，认为前房切口与巩膜瓣相连有利于手术操     

新型弹性开放襻前房型人工晶体植入临床观察

本文采用巩膜隧道切口对白内障术后后囊不完整的９６例（７０只眼）行新型弹性开放襻前房型人工晶体（ＡｎｔｅｒｉｏｒＣｈａｍｂｅｒＩｎ－ｔｒａｏｃｕｌａｒＬｅｎｓ，ＡｃＩＯＬ）植入术。所有７０只眼术后矫正视力等于或超过术前最佳矫正视力。５２只眼（７４．３％）术后视力≥０．５。术后无严重并发症。结果显示新型弹性开放襻前房型人工晶体植入安全、有效     

无缝线切口二期后房型人工晶状体植入术疗效观察

目的评价无缝线切口二期后房型人工晶状体植入术的疗效。方法对 ２２眼无晶状体眼患者分别采用３．５ ｍｍ（Ａ组 １０眼）及 ５．５ ｍｍ（Ｂ组 １２眼）的反眉状巩膜隧道切口，二期植入 ６ ｍｍ折叠式丙烯酸脂类及一体式 ＰＭＭＡ后房型人工晶状体，并与同期 １２眼６ ｍｍ常规角膜缘切口（Ｃ组），二期 ６ ｍｍ一体式 ＰＭＭＡ后房型人工晶状体植人对比。结果随访 ３～１５个月，无缝线切口组术后矫正视力均优于及等于术前最佳矫正视力，其中≥０．５者 Ａ组 ９眼（９０％），Ｂ组 ９眼（７５％）。缝线切口组，术后矫正视力优于及等于术前最佳矫正视力１０眼（８３． ５％）， ≥０．５者７眼（５８．３％）。结论采用无缝线切口二期后房型人工晶状体植人可明显降低角膜散光，减轻术后炎症反应及增加手术的安全性，是矫正无晶状体眼屈光不正的一种较理想的方法。     

复杂无晶状体眼的二期后房型人工晶状体植入术

目的：探讨复杂无晶状体眼的二期后房型人工晶状体植入术的方法和效果。方法：对46例53只眼伴有不同程度眼前段结构紊乱、前房玻璃体疝、后囊膜缺损、玻璃体切除术后的复杂无晶状体眼患者，联合行眼前段重建、前段玻璃体切除、人工晶状体缝线固定等术式及二期植入后房型人工晶状体。术后随访5～18个月。结果：术后裸眼视力均达到或优于术前矫正视力，其中术后裸眼视力≥0．3者45只眼(84．9％)。术后瞳孔圆者42只眼，人工晶状体正位者48只眼，4只眼稍偏位，仅1只眼人工晶状体倾斜。结论：复杂无晶状体眼的二期后房型人工晶状体植入术可取得满意效果，熟练的操作技巧和使用高质量粘弹剂是手术成功的关键。     

前房人工晶体植入术100例

目的探讨前房人工晶体植入术的手术方法和效果。方法对100例（103只眼）前房人工晶体植入术的患者进行回顾性研究。结果矫正视力＜0．1者2只眼（1.9％），0．1～0．4者25只眼（24.3％），≥0．5者75只眼（73．5％），≥1．0者31只眼（30．4％）。除外合并其它严重影响视力恢复因素的眼外，矫正视力≥0．5者为89．3％。结论虽然前房人工晶体多在有并发症的眼中植入．只要妥善处理仍能获得良好视力     

无囊膜支撑的折叠式人工晶体植入术

为探讨在无囊膜的无晶体眼中植入折叠式人工晶体的手术方法和疗效,通过颞侧透明角膜隧道切口,对超声乳化白内障吸除术后囊膜缺如的７只眼一期植入折叠式人工晶体,对白内障术后囊膜缺如的１６只无晶体眼二期植入折叠式人工晶体,用聚丙烯缝线将人工晶体襻固定于睫状沟中。结果：２２只眼人工晶体正位,１只眼人工晶体稍向下移位。一期植入术后１周,平均视力为０．５６,术后１个月,全部矫正视力高于０．５。二期植入后的矫正视力等于或高于术前最佳矫正视力,１３只眼（８１．２５％）裸眼视力达到０．５,５只眼（３１．２５％）达到１．０。术后角膜散光无明显变化,未发现严重并发症。结论：通过颞侧透明角膜隧道切口及睫状沟缝合固定襻的折叠式人工晶体植入术是矫正无晶体眼闭合式技术,并可作为处理超声乳化术中晶体脱位的有效方法。     

后囊破损的Ⅱ期后房型人工晶体植人术

目的探讨后囊破损Ⅱ期后房型人工晶体植入术的临床疗效。方法对２２例（２２只眼）后囊破损的白内障术后患者,根据后囊破损的大小和位置,分别采用睫状沟或囊袋内固定和缝线睫状沟单襻或双襻固定的Ⅱ期后房型人工晶体植入术。结果后囊破损的Ⅱ期后房型人工晶体植入术术后矫正视力≥０．５者占５９．１％（１３例）,术后前房及人工晶体表面渗出者占２２．７％（５例）,而同期所做的后囊破损的Ⅰ期后房型人工晶体植入术者术后矫正视力≥０．５者占４０％,术后前房及晶体表面渗出者占４０％。结论后囊破损的白内障患者,在破损的范围不能确定或范围过大时,主张选择Ⅱ期后房型人工晶体植入术。     

眼前段结构紊乱的二期后房型人工晶状体植入

目的 探讨重建眼前段结构,以机化膜为依托行二期后房型人工晶体状体植入手术的方法,并评价其疗效。方法 对不同程度眼前段结构紊乱８６只眼前眼前段结构重建及人工晶状体植入术。包括部分穿透性角膜移植术、前粘连松解术、虹膜根部离断缝合术、后粘连松解术、瞳孔成形术、瞳孔区机化膜造孔及以机化膜为依托的二期后房型人工晶状体植入术。随访３～３２个月。结果 ８６只眼手术顺利。术后视力≥０．５者７１只眼（８２．６％）,     

门诊后房型人工晶体植入术的体会

对５３例（５４眼）门诊白内障手术合并后房型人工晶体植入进行随访，其中老年性自内障２９眼，并发性白内障１４眼，外伤性白内障９眼，人工晶体二期植入２眼。术后视力≥０．５者２５眼（４６．３％），矫正视力≥０．５者４９眼（９０．７％）。术后并发症和国内其他报道相似。     

Strabisme Alternant - Etude clinique - traitement

The author defines motor and sensory alternation: the term alternation should not be used in isolation, it should always be accompanied by the name of the parameter concerned. Sensory alternation is always found together with motor alternation but the reverse is not true.The examining criteria for a diagnosis of sensory alternation are given, sensory alternation must not be confused with alternating inhibition. Working from clinical observations of cases of motor alternating strabismus, the author selects 2 types of binocular sensory relations which allow one to differentiate between:- cases of primary alternating strabismus- cases of secondary alternating strabismusThese forms will develop in different ways; in both cases a cure is possible providing that the right treatment is prescribed and once prescribed carefully followed, etc. It is always a case of serious forms of strabismus whose developmental period is spread over several years.According to the authors, the frequency of cases of true primary strabismus is from 1–3%, the frequency of cases of secondary alternating strabismus varies according to the type of therapy practised on cases of monocular strabismus with amblyopia. These latter will become cases of alternating strabismus under the influence of certain types of therapy carried out over several years (penalization, rocking, alternated occlusion, etc...).Experimental data on kittens confirm clinical data; kittens placed in abnormal environments during the sensitive period will show modification in the distribution of cortical cells and the absence of binocular cells (either because the excitation of the two eyes was not simultaneous, or not identical: artificial strabismus, occlusion, opaque glasses). This disturbances become irreversible after a certain period of exposure (a function of age, length of exposure, etc...).It is thus necessary to bear in mind: 1) the iatrogenic risks of certain orthoptic treatments, 2) the necessity for a binocular form of treatment as soon as possible, as once a certain stage is passed, cortical plasticity diminishes and the elaboration of normal binocular relations becomes impossible.

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Effects of Adenosine Agonists on Intraocular Pressure and Aqueous Humor Dynamics in Cynomolgus Monkeys

The effects of single or multiple topical doses of the relatively selective A₁adenosine receptor agonists (R)-phenylisopropyladenosine (R-PIA) and N⁶-cyclohexyladenosine (CHA) on intraocular pressure (IOP), aqueous humor flow (AHF) and outflow facility were investigated in ocular normotensive cynomolgus monkeys. IOP and AHF were determined, under ketamine anesthesia, by Goldmann applanation tonometry and fluorophotometry, respectively. Total outflow facility was determined by anterior chamber perfusion under pentobarbital anesthesia. A single unilateral topical application of R-PIA (20–250 μg) or CHA (20–500 μg) produced ocular hypertension (maximum rise=4.9 or 3.5 mmHg) within 30 min, followed by ocular hypotension (maximum fall=2.1 or 3.6 mmHg) from 2–6 hr. The relatively selective adenosine A₂antagonist 3,7-dimethyl-1-propargylxanthine (DMPX, 320 μg) inhibited the early hypertension, without influencing the hypotension. Neither 100 μg R-PIA nor 500 μg CHA clearly altered AHF. Total outflow facility was increased by 71% 3 hr after 100 μg R-PIA. In conclusion, the early ocular hypertension produced by topical adenosine agonists in cynomolgus monkeys is associated with the activation of adenosine A₂receptors, while the subsequent hypotension appears to be mediated by adenosine A₁receptors and results primarily from increased outflow facility.