微波佐治小儿支气管肺炎104例的临床观察

目的观察微波辅助治疗小儿支气管肺炎的临床疗效。方法将104例支气管肺炎患儿随机分为微波治疗组（微波组）和对照组。微波组在常规治疗基础上加用脉冲式微波治疗（2次/d,每次30min,连续治疗3d）,对照组采用常规治疗（抗感染、氧疗、气道清理、退热等）。结果微波组有效率94.12%,对照组77.65%。2组间疗效有显著性差异（P〈0.05）。结论微波理疗治疗儿童支气管肺炎疗效显著。     

微波辅助治疗小儿支气管肺炎51例临床观察

目的探讨微波治疗对小儿支气管肺炎的疗效。方法102例支气管肺炎患儿随机分为对照组和治疗组,两组均给予抗感染、雾化吸入、口服止咳化痰药等基础治疗,治疗组加用脉冲式微波辅助治疗（每天2次每次15min连续治疗5d）,观察其疗效。结果治疗组显效31例（60.78%）,有效16例（31.38%）,无效4例（7.84%）;对照组显效19例（37.25%）,有效17例（33.3%）,无效15例（29.41%）。两组治疗结果经统计学处理,治疗组与对照组比较差异有显著性（P〈0.01）。结论微波治疗对小儿支气管肺炎疗效显著。     

微波辅助治疗小儿支气管肺炎的观察及分析

目的观察微波辅助治疗小儿支气管肺炎的疗效.方法将201例小儿支气管肺炎患者分成治疗组和对照组.治疗组在常规药物治疗同时用微波辅助治疗,对照组仅常规药物治疗,疗程为5天.结果治疗组有效率为97%,对照组有效率为87.9%,平均治疗天数治疗组比对照组少.结论微波辅助治疗小儿支气管肺炎有显著疗效并可缩短疗程,减轻药物的应用.     

阿奇霉素与热毒宁联合治疗小儿支气管肺炎的临床疗效观察

目的：观察阿奇霉素与热毒宁联合治疗小儿支气管肺炎的临床疗效。方法选取支气管肺炎患儿75例,随机分为对照组与观察组。对照组（n=37）,接受阿奇霉素治疗;观察组（n=38）,接受阿奇霉素与热毒宁联合治疗。比较2组患儿的临床疗效。结果对照组总有效率为81.1%,观察组总有效率为97.4%,2组患儿总有效率比较,差异具有统计学意义（P＜0.05）。结论阿奇霉素与热毒宁联合治疗小儿支气管肺炎,总有效率显著高于单用阿奇霉素治疗,可以临床推广应用。     

肺部微波疗法加复方丹参注射液治疗小儿支气管肺炎疗效观察

目的：观察肺部微波疗法加复方丹参注射液治疗小儿支气管肺炎的临床疗效。方法肺部微波疗法加复方丹参注射液53例作为治疗组,与常规治疗的对照组53例做比较。结果治疗组总有效率96.2%,对照组总有效率77.4%,2组疗效比较差异有显著性（P<0.05）;治疗组在主要症状改善方面优于对照组（P<0.05）。结论肺部微波疗法加复方丹参注射液治疗小儿支气管肺炎疗效确切,值得临床推广。     

中西医联合治疗小儿支气管肺炎的临床疗效观察

目的：观察中西医联合治疗小儿支气管肺炎的临床效果。方法选取145例小儿支气管肺炎患者,以就诊顺序随机分为对照组（n=70）,给予患者止咳、退热、抗生素的常规用药治疗;治疗组（n=75）,在对照组的基础上给予中药治疗。7d为1个疗程,观察2组患者的疗效。结果对照组总有效率81.43%,治疗组总有效率96.00%,治疗组有效率显著高于对照组（P<0.05）。结论与单纯西药治疗相比,中西医联合治疗小儿支气管肺炎的临床疗效更好,建议将该治疗方法应用于临床中。     

微波辅助治疗小儿支气管肺炎的疗效观察

目的 探讨微波辅助治疗在小儿支气管肺炎治疗中的作用.方法 100例小儿支气管肺炎病儿分别采用微波+常规治疗(A组,50例)和常规治疗(B组,50例);评价两组疗效、退热时间、胸片正常时间、肺部罗音消失时间、咳嗽停止时间及不良反应.结果 A组总有效率92.0%,明显高于B组74.0%(x2=3.92,P＜0.05);A组退热时间、胸片正常时间较B组有显著性差异(t=4.237,4.468,P均＜0.05);A组咳嗽停止时间、肺部罗音消失时间较B组有显著性差异(t=5.628,6.604,P均＜0.01).结论 微波辅助治疗小儿支气管肺炎疗效肯定、安全,值得推广使用.     

痰热清辅助治疗小儿支气管肺炎60例疗效观察

目的：痰热清辅助治疗小儿支气管肺炎。方法：对120例（其中治疗组60例,对照组60例）小儿支气管肺炎患者,在采用常规治疗的同时辅助痰热清治疗。结果：治疗纽优于对照组,经统计学处理差异有显著性。结论：痰热清辅助治疗小儿支气管肺炎有明显疗效值得推广。     

神阙贴穴位贴敷辅助治疗小儿支气管肺炎的临床观察

目的观察神阙贴穴位贴敷辅助治疗小儿支气管肺炎的治疗效果。方法选择2012-02-2013-08收治的1-12个月的小儿支气管肺炎患儿82例,随机分为观察组和对照组,两组均予以常规综合治疗,观察组在综合治疗的基础上加神阙贴穴位贴敷辅助治疗,对照组仅予以常规综合治疗。结果 （1）观察组总有效率优于对照组,差异有统计学意义（P〈0.05）;（2）两组临床指标（症状、体征消失时间和住院天数）比较差异无统计学意义（P〉0.05）;（3）治疗后7 d胸片炎症阴影的恢复观察组明显优于对照组,差异有统计学意义（P〈0.05）;（4）两组均未见明显不良反应,治疗后WBC、GRAN#、CRP、HsCRP、HGB、MCV的变化比较差异无统计学意义（P〉0.05）。结论神阙贴穴位贴敷有助于促进小儿支气管肺炎炎症吸收,提高疗效的作用,是辅助治疗小儿支气管肺炎的一种疗效确切、方法简便、价格低廉、无毒副作用的方法,值得临床推广。     

易坦静辅助治疗小儿支气管肺炎96例临床观察

目的观察易坦静辅助治疗小儿支气管肺炎的临床疗效。方法选择小儿支气管肺炎患者96例,随机分为对照组与治疗组各48例,观察两组的病情改善情况。结果治疗组总有效率为91.7%,对照组总有效率为72.9%,两组对比具有显著性差异（P〈0.05）,具有统计学意义。结论临床上应用易坦静辅助治疗小儿支气管肺炎,可以有效的控制儿童呼吸道疾病,缩短治疗时间,且安全性高、无不良反应,值得临床上进一步推广使用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.