非接触式眼压计与Goldmann压平眼压计测量眼压的比较

目的 :比较非接触式眼压计 ( NCT)和 Goldm ann压平眼压计测量眼压的差异。方法 :对 112例 ( 2 2 0眼 )志愿者分别进行 NCT和 Goldmann压平眼压计眼压测量及中央角膜厚度测量 ,并对其中 16 8眼进行自动验光检查。结果 :NCT和 Goldmann眼压计眼压测量值分别为 1.98± 0 .6 9k Pa和 2 .34± 0 .77k Pa。 NCT眼压测量值较 Goldmann眼压测量值偏低 0 .36± 0 .37k Pa( P<0 .0 5 )。眼压在 1.33～ 2 .6 7k Pa内 ,二种眼压计测量眼压值偏差最小。角膜厚度和眼球屈光度与 NCT眼压测量值分别呈明显正相关和负相关。结论 :NCT眼压测量值较Goldmann眼压测量值偏低 ,NCT眼压值为临界眼压时 ,应应用 Goldm ann压平眼压计校正     

动态轮廓眼压计与压平眼压计的比较

目的:评价和比较动态轮廓眼压计和Goldmann压平眼压计测得的LASIK手术后眼压值。方法:接受准分子激光原位角膜磨镶术(LASIK)的近视患者34例68眼,分别于术前和术后3mo使用动态轮廓眼压计(Pascal dynamic contour tonometer,PDCT)和Goldmann压平眼压计(the Goldmann applanation tonometer,GAT)进行眼压测量。比较手术前后两种测量方法测得的眼压值的差异。多元线性相关分析研究GAT,PDCT测量值和角膜曲率及角膜中央厚度(CCT)之间的相关性。结果:LASIK手术后GAT测量值较术前低,而PDCT值和术前比较差异则无统计学意义。角膜曲率、CCT和GAT读数呈线性相关,而与PDCT读数无关。结论:GAT测量得到的眼压低于实际值。PDCT测眼压不受角膜曲率和中央角膜厚度影响。     

iCare回弹式眼压计与Goldmann压平眼压计测量结果的比较

目的对比iCare回弹式眼压计（RBT）与Goldmann压平眼压计（GAT）测量眼压的一致性,评价RBT测量眼压的准确性及安全性。方法研究为诊断性试验评价。分别用2种眼压计测量角膜正常的患者52例104眼,其中男28例,女24例;年龄19～76岁,以GAT眼压值作为基准分为5组：≤10mmHg、11～20mmHg、21～30mmHg、31～40mmHg、≥41mmHg组。评估2种测量方法的眼压值差值及其与眼压的关系。对RBT眼压值随GAT眼压值变化的关系进行评价。结果 RBT测得的眼压读数为（17.20±9.13）mmHg,GAT测得的眼压读数为（17.13±8.94）mmHg,二者差异无统计学意义（t=0.260,P=0.795）。60.58%的患者2种方法测得的眼压差值在1mmHg以内。5个组中,GAT眼压与RBT眼压的绝对差值随着眼压读数的增高而加大,最大值在≥41mmHg组,二者的最大绝对差值〈4mmHg。RBT眼压读数随着GAT眼压读数的改变而变化,二者的变化呈现良好的相关性（r=0.917,P〈0.01）,但与GAT测量法比较,RBT测得的眼压值均稍高。当GAT眼压值〉21mmHg时,RBT测量的敏感度和特异度分别为95.5%和98.8%。RBT测量后25%的患者主诉有异物感和眼干。结论 iCareRBT测量眼压具有良好的耐受性和安全性,与GAT测量眼压具有较好的相关性,适用于临床。     

PASCAL动态轮廓眼压计临床应用的初步报告

目的:验证动态轮廓眼压计(DCT)的临床性能。方法:对81例143眼青光眼及可疑病例青光眼患者用DCT测量眼内压(IOP);132眼同时用Goldmann压平眼压计(GAT)测量眼压,部分病例同时用NIDEKUP-1000型角膜测厚仪测量中央角膜厚度(CCT)。GAT与DCT测量结果采用配对t检验,GAT、DCT测量值与CCT的关系及DCT测量值与眼脉动振幅(OPA)的相关关系采用Spearman双变量相关分析。结果:①DCT和GAT测得的眼压均数分别为(18.6±3.9)mmHg和(17.4±4.1)mmHg;DCT测得的眼压值高于GAT,其差值均数为(1.1±2.3)mmHg;两种眼压计测得的眼压值呈正相关(r=0.83,P<0.01)。②116眼同时完成了DCT眼压测量及CCT测量,两者相关系数r=0.03,P=0.77;113眼同时完成了GAT眼压测量及CCT测量,两者相关系数r=0.28,P=0.003。③143眼同时记录了DCT眼压值和眼脉动振幅(OPA),其均数分别为(18.6±3.9)mmHg和(2.6±1.1)mmHg,两者的相关系数r=0.32,P<0.01。结论:以上结果初步证实:①DCT眼压计测量值与GAT眼压测量值高度相关,但DCT测量值略高于GAT测量值,提示DCT可用于临床诊断。②DCT测量值与CCT不相关,GAT测量值与CCT显著相关,提示DCT在青光眼诊断中有独特优势。③DCT测量的OPA与IOP值显著相关,相关的机制及临床意义有待探讨。     

凸面眼压计与Goldmann压平眼压计C值测量结果比较

目的比较我们自行研制的凸面眼压计与Goldmann压平眼压计(以下简称Goldmann眼压计)所测量的C值,以评价凸面眼压计在临床的应用价值。方法分别应用凸面眼压计与Goldmann眼压计测量15例(30只眼)正常人的C值;15例(15只眼)青光眼患者的C值,并作统计学分析。结果凸面眼压计C值是Goldmann眼压计C值的两倍,两种眼压计C值测量结果差异有显著性意义(P<0.01)。结论用凸面眼压计所测得的C值更接近于流体压力方法测得的C值,因此凸面眼压计更适合于眼压描记,具有临床使用价值。     

动态轮廓眼压计在正常人群中的应用及其影响因素分析

目的评价动态轮廓眼压计（DCT）与Goldmann压平眼压计（GAT）测量值之间的关系,寻找DCT眼压测量值的影响因素;分析DCT所测眼压脉动振幅（OPA）与DCT眼压值、中央角膜厚度（CCT）、角膜屈光力（CCV）、眼轴长度（AL）、前房深度（ACD）、收缩压（SBP）、舒张压（DBP）和心率（HR）的关系。方法分别测量正常人60例60眼的DCT眼压、GAT眼压、CCT、CCV、AL、ACD以及HR、SBP、DBP等指标,比较GAT、DCT2种眼压计测量的相关性及DCT测量值的影响因素。结果 DCT与GAT所测眼压平均值分别为（16.04±2.57）mmHg和（14.20±2.93）mmHg。DCT眼压值较GAT眼压值高,差异有统计学意义（t=6.454,P〈0.01）。DCT眼压值与GAT眼压值呈正相关（r=0.684,P〈0.01）。DCT眼压值与CCT不相关（r=0.212,P=0.105）,GAT眼压值与CCT呈正相关（r=0.291,P=0.024）。60例正常人的OPA均值为（2.50±0.89）mmHg,OPA与年龄、DCT眼压值、CCT、SBP、DBP、HR均不相关（P〉0.05）,与CCV呈正相关（r=0.343,P=0.007）。结论在正常人群中DCT眼压值与GAT眼压值有较好的相关性,DCT的眼压测量值不受CCT、CCV等因素的影响。DCT眼压值、CCT、SBP、DBP、HR等对OPA无明显影响。     

PASCAL动态轮廓眼压计与Goldmann压平眼压计在非青光眼人群中眼压测量值的比较及一致性分析

目的探讨在不同的中央角膜厚度(CCT)下PASCAL动态轮廓眼压计(DCT)与Goldmann压平眼压计(GAT)眼压(IOP)测量值的相关性,评价两者测量值的一致性及临床上两种眼压计测量值相互替换的可能性。方法非青光眼病例87例(168只眼)分别用DCT和GAT进行眼压测量,两种仪器的测量顺序随机。同时,用NIDEK UP-1000型角膜测厚仪测量CCT。DCT与GAT眼压测量值的相关性采用Spearson双变量相关分析,Bland-Altman分析法评价两种仪器IOP测量值的一致性。结果 (1)在不同的角膜厚度下DCT与GAT测得的IOP值均显著相关(CCT≤520μm,n=24,r=0.67,P<0.001;520μm580μm,n=44,r=0.61,P<0.001)。(2)DCT眼压测量值与CCT不相关(r=0.14,P=0.08),GAT眼压测量值与CCT显著相关(r=0.59,P<0.001)。(3)Bland-Altman一致性分析显示两种仪器的差值的均值为-0.9mm Hg,一致性界限为(-5.6 mm Hg,3.9 mm Hg)。结论 (1)在不同的角膜厚度下DCT与GAT的眼压测量值均显著相关。(2)DCT眼压测量值与CCT值不相关,GAT眼压测量值与CCT值显著相关。(3)一致性分析显示两者测量值的一致性界限跨度较宽,二者的IOP值不可简单地相互代替。     

Tono-Pen眼压计与Goldmann眼压计的临床比较

目的:了解Tono-Pen眼压计的临床实用性。方法:62例(111只眼)随机先后用Tono-Pen眼压计与Goldmann眼压计进行眼压测量,比较两种眼压计测量值的差异。结果:111只眼中,用Goldmann眼压计测量的眼压平均值为(15.82±4.88)mmHg,用Tono-Pen眼压计测量的眼压平均值为(16.34±4.33)mmHg,两者有显著性差异。眼压在9～30mmHg范围时,两种眼压计的测量值之差为(-0.51±2.24)mmHg,差异无显著性。在眼压低于9mmHg时,有过高估计眼压的趋向;在眼压高于30mmHg时,有过低估计眼压的趋向。Tono-Pen眼压计与Goldmann眼压计的相关系数为0.865,呈密切相关。结论:Tono-Pen眼压计与Goldmann眼压计有很好的相关性,尤其是在眼压为9～30mmHg范围。眼科学报 2002;18:226-229.     

非接触眼压计测量的评价——与Goldmann眼压计的比较

目的 :对比非接触式眼压计 (NCT)与Goldmann眼压计所测量的眼压值以评价非接触式眼压计在临床的应用价值。方法 :10 5例 2 0 9只眼纳入本观察 ,其中 14 2只眼作了验光、眼轴及角膜曲率测量 ,并调查患者对两种眼压计的接受度。结果 :两种眼压计测量结果的相关系数为 0 975 ,两者差异有显著性 (t值 -7 949,P <0 0 0 1)。非接触式眼压计的测量结果高于Goldmann眼压计 ,尤其在眼压 >2 1mmHg组更为明显 (t值 -5 5 0 6,P <0 0 0 1)。角膜曲率、屈光度、散光、眼轴与两者测量值间差d无相关性 ,相关系数分别为 -0 0 5 4,-0 0 41,-0 13 5 ,0 113 ,P值均 >0 0 5。患者对非接触式眼压计的接受程度大于Goldmann眼压计结论 :非接触式眼压计可用于临床普查 ,但在青光眼的临床工作中建议使用Goldmann压平式眼压计     

非接触式眼压计与Goldmann压平眼压计测量眼压的比较

目的:比较非接触眼压计(non-contacttonometer,NCT)与Goldmann压平眼压计(GAT)测量眼压的差异,以评价非接触式眼压计在临床青光眼患者及疑似青光眼患者中的的应用价值。方法:志愿者174例348眼分别由专人进行非接触眼压计(NCT)与Goldmann压平眼压计眼压测量。结果:非接触眼压计(NCT)的测量结果低于Gold-mann压平眼压计且差异有显著性(19.6vs23.4,P<0.05),两者相关系数为r=0.783,差异在眼压>30mmHg组更为明显,相关系数为0.334。结论:非接触眼压计(NCT)可以用于临床普查,在青光眼的临床工作中建议使用Goldmann压平眼压计矫正。     

Differences between Goldmann Applanation Tonometry and Dynamic Contour Tonometry in pseudoexfoliation syndrome

Purpose: To evaluate differences between Goldmann Applanation Tonometry (GAT) and Dynamic Controur Tonometry (DCT) in eyes with pseudoexfoliation syndrome (PEX). Methods: Thirty‐eight patients (38 eyes) with PEX in both eyes (pseudoexfoliative group, PG) as well as 19 patients (19 eyes) without PEX in either eye (control group, CG), were included. All eyes were phakic. GAT, DCT, the central corneal thickness (CCT) and the axial length of the eyeball (AL) were measured and the difference between GAT and DCT (dIOP) was calculated. Differences in dIOP between CG and PG and correlations of dIOP with CCT and AL were examined. Results: dIOP was significantly (P = 0.02) higher in PG (mean value 3.69 mmHg), compared with CG (mean value 2.15 mmHg). In PG (but not in CG), dIOP was also significantly correlated with AL but not with CCT. Conclusion: The fact that dIOP was significantly higher in PG than in CG implies that PEX may affect ocular biomechanical properties. The significant association of dIOP with AL but not with CCT is in agreement with previous reports and complies with the fact that pseudoexfoliative material is not deposited in corneal stroma.     

Assessment of intraocular pressure measured by Reichert Ocular Response Analyzer, Goldmann Applanation Tonometry, and Dynamic Contour Tonometry in healthy individuals

AIM: To investigate the accuracy of intraocular pressure (IOP) as measured by a Reichert Ocular Response Analyzer (ORA), as well as the relationship between central corneal thickness (CCT) and IOP as measured by ORA, Goldmann applanation tonometry (GAT), and dynamic contour tonometry (DCT). METHODS: A total of 158 healthy individuals (296 eyes) were chosen randomly for measurement of IOP. After CCT was measured using A-ultrasound (A-US), IOP was measured by ORA, GAT, and DCT devices in a randomized order. The IOP values acquired using each of the three tonometries were compared, and the relationship between CCT and IOP values were analyzed separately. Two IOP values, Goldmann-correlated IOP value (IOPg) and corneal-compensated intraocular pressure (IOPcc), were got using ORA. Three groups were defined according to CCT: 1) thin cornea (CCT<520μm); 2) normal-thickness cornea (CCT: 520–580μm); and 3) thick cornea (CCT>580μm) groups. RESULTS: In normal subjects, IOP measurements were 14.95±2.99mmHg with ORA (IOPg), 15.21±2.77mmHg with ORA (IOPcc), 15.22±2.77mmHg with GAT, and 15.49±2.56mmHg with DCT. Mean differences were 0.01±2.29mmHg between IOPcc and GAT (P>0.05) and 0.28±2.20mmHg between IOPcc and DCT (P>0.05). There was a greater correlation between IOPcc and DCT (r=0.946, P=0.000) than that between IOPcc and GAT (r=0.845, P=0.000). DCT had a significant correlation with GAT (r=0.854, P=0.000). GAT was moderately correlated with CCT (r=0.296, P<0.001), while IOPcc showed a weak but significant correlation with CCT (r=?0.155, P=0.007). There was a strong negative correlation between CCT and the difference between IOPcc and GAT(r=-0.803,P=0.000), with every 10μm increase in CCT resulting in an increase in this difference of 0.35mmHg. The thick cornea group (CCT>580μm) showed the least significant correlation between IOPcc and GAT (r=0.859, P=0.000); while the thin cornea group (CCT＜520μm) had the most significant correlation between IOPcc and GAT (r=0.926, P=0.000). The correlated differences between IOPcc and DCT were not significant in any of the three groups (P>0.05). CONCLUSION: Measurement of IOP by ORA has high repeatability and is largely consistent with GAT measurements. Moreover, the ORA measurements are affected only to a small extent by CCT, and are likely to be much closer to the real IOP value than GAT.     

等高线眼压测量与压平眼压测量的临床比较及其与角膜厚度的关系

目的：对比最近引进的动态等高线眼压测量（DCT）与气动眼压测量（PTG）和Goldmann压平眼压测量（GAT）的眼压读数值。并将读数与中央角膜厚度（CCT）联系起来分析它们之间的关系。 设计：前瞻性的、横断面的观察和仪器审定的研究。纳入研究的258眼（258人）均为前节检查结果正常的眼睛。无论是否诊断为青光眼或可疑青光眼。在角膜厚度测量之后。按照随机的顺序进行DCT,PTG,GAT的眼压测量。将DCT,PTG,GAT测量所得的读数之间进行相互比较,并与CCT进行比较。 结果：用GAT测量时,CCT偏薄的眼睛眼压测量值偏低。CCT与GAT之间存在显著相关性（Pearson。P〈0．001）。回归结果为0．25mmHg／10pm（R^2=0．060）。cur的变化对PTG（P=0．10；R^2=0．01）和DCT（P=0．80；R^2〈0．01）的眼压测量值没有显著的影响。分段回归模型显示GAT读数与CCT不是线性相关的。535μm上下的斜率的对比显著性最大（P〈0．001）。 结论：Goldmann压平眼压测量的读数可能受到CCT的影响。而PTG和DCT受CCT的影响似乎要小。CCT与GAT之间的关系不是线性的。一个简单的线性关系的矫正公式可能是不正确的。     

泪膜改变对Goldmann眼压测量值的影响

目的:探讨泪膜改变对Goldmann压平眼压计测量值的影响.方法:将68例(136只眼)受检者随机分为2组,每组34例.随机选择一只眼作为实验眼.另一只眼作为对照眼.A组的实验眼采用右旋糖苷70滴眼液滴眼,B组的实验眼采用粘弹剂Viscoat滴眼.采用Goldmann眼压计测量2次眼压,比较滴眼前、后测量值的差异.结果:A组对照眼第1、2次的眼压测量值分别为(14.44±2.68)mmHg(1 mmHg=0.133 KPa)、(14.47±2.69)mmHg,两次眼压测量值的差异无统计学意义(t=-0.329,P=0.744).实验眼滴右旋糖苷70滴眼液前、后的眼压测量值分别为(14.41±2.63)mmHg、(12.94±2.59)mmHg.两次眼压测量值的差异有统计学意义(t=13.949,P=0.000).B组对照眼第1、2次的眼压测量值分别为(14.29±2.96)mmHg、(14.35±3.12)mmHg,两次眼压测量值的差异无统计学意义(t=-0.466,P=0.644).实验眼滴Viscoat前、后的眼压测量值分别为(14.53±3.13)mmHg、(11.18±3.07)mmHg,两次眼压测量值的差异有统计学意义(t=22.126,P=0.000).两组的实验眼滴眼后的眼压均呈一致性的下降.结论:泪膜的改变可以使Goldmann压平眼压计的测量值产生偏差.     

Comparison of the iCare rebound tonometer and the Goldmann applanation tonometer over a wide IOP range

Background The aim of this study was to compare the intraocular pressure (IOP) results measured by the iCare rebound tonometer with those obtained by the Goldmann applanation tonometer (GAT) over a wide range of IOP values. Furthermore, the comfort level of the iCare measurement was evaluated. Method The study included 75 eyes of 75 patients. The patients were divided into three groups (7–15 mmHg n = 25, 16–22 mmHg n = 25, 23–60 mmHg n = 25). The measurements were taken by two independent observers in a masked fashion. All patients were asked about discomfort during the iCare measurement. To establish the agreement between the two devices, a Bland-Altman analysis was performed. Results Overall, the 95% confidence interval of the differences between the two devices was −8.67 to 10.25 mmHg and in 62.7%, the iCare measurement was within ±3 mmHg of the GAT measurements. The distribution of the differences in IOP was similar, from 7–22 mmHg. In the higher IOP range (23–60 mmHg), however, the deviation was almost twice as large. The measurement with the iCare tonometer was well tolerated; 100% of the patients denied any discomfort. Conclusions The iCare tonometer is a mobile alternative to GAT in a low to moderate IOP range, but our findings show a greater deviation than previously reported. In high IOP values, measurements with the iCare tonometer do not correlate well with GAT.     

The effect of contact lens-induced corneal edema on Goldmann applanation tonometry and dynamic contour tonometry

Purpose  To evaluate the effect of contact lens-induced corneal edema on intraocular pressure (IOP) measurements using Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) in Asian subjects. Participants  The study included 40 eyes of 20 normal volunteers with no evidence of ocular disease. Methods  Forty eyes of 20 healthy volunteers were required to wear soft contact lenses for 2 hours to induce corneal swelling. Central corneal thickness (CCT) and IOP were measured before and immediately after contact lens wear using specular microscope, GAT, and DCT. The IOP measurements by GAT and DCT were compared. The changes in the CCT and the IOP measurements after wearing contact lenses were assessed. Results  The mean CCT of the 40 eyes evaluated was 532.6 ± 31.6 μm. The mean IOP was 11.78 ± 2.04 mmHg for the GAT and 14.46 ± 1.89 mmHg for the DCT, and the difference was statistically significant (P < 0.001). After wearing contact lenses, the mean CCT was 553.2 ± 34.3 μm, which was 20.6 ± 12.9 μm greater than before wearing them (P < 0.001). The mean IOP measurements of the GAT and DCT were decreased after wearing the contact lenses. The mean decrease of the GAT values was 0.43 ± 1.95 mmHg, which was not statistically significant (P = 0.175). However, the mean decrease of the DCT readings, which was 0.75 ± 1.74 mm Hg, was statistically significant (P = 0.010). Conclusion  The IOP measurements with DCT were significantly higher than those with GAT in healthy Asian eyes. Although the mean IOP measurements of both the GAT and the DCT were decreased in the edematous cornea, IOP measurements of the DCT were more affected by corneal edema than were the GAT. The authors have no proprietary, commercial, or financial interests in any of the products described in this study.