共查询到20条相似文献,搜索用时 0 毫秒
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Nicolas Brugger MD Mohammad Kassar MD George C. M. Siontis MD Sonja Widmer MD Taishi Okuno MD Mirjam G. Winkel MD Noé Corpataux MD Christoph Gräni MD Lutz Büllesfeld MD Lukas Hunziker MD Thomas Pilgrim MD Stephan Windecker MD Fabien Praz MD 《Catheterization and cardiovascular interventions》2021,98(7):1404-1412
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Mathias Orban Martin Orban Hasema Lesevic Daniel Braun Simon Deseive Carolin Sonne Lisa Hutterer Christian Grebmer Alexander Khandoga Jürgen Pache Julinda Mehilli Heribert Schunkert Adnan Kastrati Christian Hagl Axel Bauer Steffen Massberg Peter Boekstegers Michael Nabauer Ilka Ott Jörg Hausleiter 《Journal of interventional cardiology》2017,30(3):226-233
Objectives
To determine predictors for long‐term outcome in high‐risk patients undergoing transcatheter edge‐to‐edge mitral valve repair (TMVR) for severe mitral regurgitation (MR).Background
There is no data on predictors of long‐term outcome in high‐risk real‐world patients.Methods
From August 2009 to April 2011, 126 high‐risk patients deemed inoperable were treated with TMVR in two high‐volume university centers.Results
MR could be successfully reduced to grade ≤2 in 92.1% of patients (116/126 patients). Long‐term clinical follow‐up up to 5 years (95.2% follow‐up rate) revealed a mortality rate of 35.7% (45/126 patients). Repeat mitral valve treatment (surgery or intervention) was needed in 19 patients (15.1%). Long‐term clinical improvement was demonstrated with 69% of patients being in NYHA class ≤II. In a multivariable Cox regression analysis, the post‐procedural grade of MR (hazard ratio [HR] 1.55 per grade, P = 0.035), the left ventricular ejection fraction (HR 0.58 for difference between 75th and 25th percentile, P = 0.031) and the glomerular filtration rate (HR 0.33 for 75th vs 25th percentile, P < 0.001) were independent predictors for long‐term mortality. Patients with primary MR and a post‐procedural MR grade ≤1 had the most favorable long‐term outcome.Conclusions
This study determines predictors of long‐term clinical outcome after TMVR and demonstrates that the grade of residual MR determines long‐term survival. Our data suggest that it might be of benefit reducing residual MR to the lowest possible MR grade using TMVR—especially in selected high‐risk patients with primary MR who are not considered as candidates for surgical MVR.5.
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Shudo Y Nakatani S Sakaguchi T Miyagawa S Yoshikawa Y Takeda K Saito S Takeda Y Sakata Y Yamamoto K Sawa Y 《Echocardiography (Mount Kisco, N.Y.)》2012,29(4):445-450
Background: Restrictive mitral annuloplasty (RMA) is widely employed for patients with functional mitral regurgitation (MR). Its improvement of left ventricular (LV) function has been demonstrated by only a gradual increase in LV ejection fraction (EF) in the chronic phase. However, the detailed evaluation of changes in LV function has not been fully elucidated in functional MR patients before and after RMA. Therefore, we performed two‐dimensional speckle tracking echocardiography (2D‐STE), which enables accurate evaluation of myocardial deformation and rotation that are undetectable by conventional echocardiography. Methods: We studied 13 patients (mean age 61 ± 10 years) with functional MR associated with cardiomyopathy undergoing RMA. In addition to conventional echocardiographic measurements, 2D‐STE was performed to measure peak systolic radial (RS), circumferential (CS), and longitudinal (LS) strains and twist before and 4 ± 2 weeks after surgery. LV twist was defined as the difference between the apical and basal rotations. Results: After RMA, EF and LS remained unchanged, but RS and CS were significantly improved at the mid‐LV (RS, 20.6 ± 10.8 vs 24.5 ± 11.6%; CS, ?9.6 ± 5.2 vs ?12.8 ± 5.6%) and at the apex (RS, 15.0 ± 12.2 vs 18.7 ± 8.6%; CS, ?4.4 ± 3.0 vs ?7.8 ± 4.8%). RS and CS were unchanged at the base. The apical and basal rotations changed significantly, from 3.5°± 0.7° to 9.2°± 2.1°, and ?2.1°± 0.7° to ?3.8°± 1.0°, respectively. Consequently, the LV twist increased significantly, from 5.6°± 1.0° to 13.0°± 1.9°. Conclusions: Radial and circumferential strains and LV twist increased significantly in the early postoperative period in functional MR patients after RMA and concomitant procedures. (Echocardiography 2012;29:445‐450) 相似文献
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《Indian heart journal》2016,68(3):399-404
Mitral valve disease affects more than 4 million people in the United States. The gold standard of treatment in these patients is surgical repair or replacement of the valve with a prosthesis. The MitraClip (Abbott Vascular, Menlo Park, CA) is a new technology, which offers an alternative to open surgical repair or replacement via a minimally invasive route. We present an evidence-based clinical update that provides an overview of this technology as it relates to managing patients with significant mitral regurgitation. This review article is particularly useful to noninterventional cardiologists and interventional cardiologists who will be managing patients with this novel technology in increased volumes over the next decade but who do not perform this procedure. 相似文献
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Gender‐related clinical and echocardiographic outcomes at 30‐day and 12‐month follow up after MitraClip implantation in the GRASP registry 下载免费PDF全文
Yohei Ohno MD Davide Capodanno MD PhD Stefano Cannata MD Fabio Dipasqua MD Sebastiano Immé MD Sarah Mangiafico MD Marco Barbanti MD Margherita Ministeri MD Anna Cageggi MD Anna Maria Pistritto MD Sandra Giaquinta MD Silvia Farruggio MD Marta Chiarandà MD Giuseppe Ronsivalle MD Salvatore Scandura MD Corrado Tamburino MD PhD Piera Capranzano MD PhD Carmelo Grasso MD 《Catheterization and cardiovascular interventions》2015,85(5):889-897
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Mirjam Gauri Winkel Nicolas Brugger Stephan Windecker Fabien Praz 《Catheterization and cardiovascular interventions》2020,96(3):E393-E394
Recurrent flail leaflet represents an infrequent cause of recurrent mitral regurgitation after MitraClip. This report presents a case of recurrent severe MR due to a ruptured chorda tendineae after edge‐to‐edge repair. 相似文献
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The MitraClip Asia‐Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation 下载免费PDF全文
Edgar Tay MBBS Nasir Muda MBBS Jonathan Yap MBBS David W.M. Muller MD Teguh Santoso MBBS Darren L. Walters MD Xianbao Liu MD Eric Yamen MD Paul Jansz MD James Yip MBBS Robaayah Zambahari MBBS Jurgen Passage MD Zee Pin Ding MBBS Jian'an Wang MD Gregory Scalia MD Amiliana M. Soesanto MBBS Khung Keong Yeo MBBS 《Catheterization and cardiovascular interventions》2016,87(7):E275-E281
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Percutaneous therapy for the treatment of mitral regurgitation has emerged rapidly over the past few years. Most of the percutaneous approaches are modifications of existing surgical approaches to mitral annuloplasty or leaflet repair. Catheter-based devices mimic these surgical approaches with less procedural morbidity and mortality as a consequence of their less invasive nature. Percutaneous annuloplasty can be achieved indirectly via the coronary sinus or directly from retrograde left ventricular access. Catheter-based leaflet repair is accomplished using an implantable clip to mimic the surgical edge-to-edge technique. Several of these percutaneous approaches have been successfully used in patients to demonstrate proof of concept, while others have already stopped further development. There is increasing experience in both trials and practice to begin to define the clinical utility of percutanenous leaflet repair, and annuloplasty approaches are undergoing significant development. 相似文献
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Percutaneous mitral valve repair: a feasibility study in an ovine model of acute ischemic mitral regurgitation. 总被引:5,自引:0,他引:5
John R Liddicoat Briain D Mac Neill A Marc Gillinov William E Cohn Chi-Hui Chin Aldo D Prado Natesa G Pandian Stephen N Oesterle 《Catheterization and cardiovascular interventions》2003,60(3):410-416
Annuloplasty is the cornerstone of surgical mitral valve repair. A percutaneous transvenous catheter-based approach for mitral valve repair was tested by placing a novel annuloplasty device in the coronary sinus of sheep with acute ischemic mitral regurgitation. Mitral regurgitation was reduced from 3-4+ to 0-1+ in all animals (P < 0.03). The annuloplasty functioned by reducing septal-lateral mitral annular diameter (30 +/- 2.1 mm preinsertion vs. 24 +/- 1.7 mm postinsertion; P < 0.03). These preliminary experiments demonstrate that percutaneous mitral annuloplasty is feasible. Further study is necessary to demonstrate long-term safety and efficacy of this novel approach. 相似文献
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Rodrigo Estévez-Loureiro MD PhD Mony Shuvy MD Maurizio Taramasso MD PhD Tomas Benito-Gonzalez MD Paolo Denti MD PhD Dabit Arzamendi MD PhD Marianna Adamo MD Xavier Freixa MD PhD Pedro Villablanca MD MSc Lian Krivoshei MD Neil Fam MD PhD Konstantinos Spargias MD Andrew Czarnecki MD Dan Haberman MD Yoram Agmon MD Doron Sudarsky MD Isaac Pascual MD PhD Vlasis Ninios MD Salvatore Scianna MD Igal Moaraf MD Davide Schiavi MD Michael Chrissoheris MD Ronen Beeri MD Arthur Kerner MD Estefanía Fernández-Peregrina MD Mattia Di Pasquale MD Ander Regueiro MD PhD Lion Poles MD Andres Iñiguez-Romo MD PhD Felipe Fernández-Vázquez MD PhD Francesco Maisano MD 《Catheterization and cardiovascular interventions》2021,97(6):1259-1267
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Matthias Gröger MD Katharina P. Zeiml MD Leonhard M. Schneider MD Wolfgang Rottbauer MD Sinisa Markovic MD Mirjam Keßler MD 《Catheterization and cardiovascular interventions》2023,102(3):528-537
Aims
To evaluate the impact of tricuspid regurgitation (TR) on echocardiographic and functional outcome after mitral valve transcatheter edge-to-edge-repair (M-TEER).Methods and Results
A total of 740 patients underwent M-TEER at our center from 2010 to 2021. Patients were analyzed according to severity of concomitant TR at the time of M-TEER procedure: low-grade TR (grade ≤I [trace–mild], 279 patients [37.7%]), moderate TR (grade II, 170 patients [23.0%]) and high-grade TR (grade III-V [severe–torrential], 291 patients [39.3%]). Patients with moderate to high-grade TR had higher morbidity. Procedural success of M-TEER was achieved similarly in all groups (98.2% vs. 97.6% vs. 95.9%, p = 0.22). TR severity decreased rapidly and consistently after M-TEER to only 48.0% of high-grade TR patients after 3 months (p < 0.001) and to 46.8% after 12 months (p = 0.99). High-grade TR patients had significantly higher mortality (21.5% vs. 18.2% vs. 11.1%, p = 0.003) up to 12 months after M-TEER. However, high-grade TR did not independently predict mortality (HR 1.302, 95% CI 0.937–1.810; p = 0.116). Echocardiographic and functional outcome was similar in both secondary and primary MR patients.Conclusions
High-grade concomitant TR did not independently predict adverse outcome following M-TEER. A wait-and-observe approach for these patients is reasonable. 相似文献16.
Howard C Herrmann Sameer Rohatgi Hal S Wasserman Peter Block William Gray Andrew Hamilton Alan Zunamon Shunichi Homma Marco R Di Tullio Kimberly Kraybill John Merlino Randy Martin Leonardo Rodriguez William J Stewart Patrick Whitlow Susan E Wiegers Frank E Silvestry Elyse Foster Ted Feldman 《Catheterization and cardiovascular interventions》2006,68(6):821-828
INTRODUCTION: The Endovascular Valve Edge-to-Edge REpair STudies (EVEREST) are investigating a percutaneous technique for edge-to-edge mitral valve repair with a repositionable clip. The effects on the mitral valve gradient (MVG) and mitral valve area (MVA) are not known. METHODS: Twenty seven patients with moderate to severe or severe mitral regurgitation (MR) were enrolled. Echocardiography was performed preprocedure, at discharge, and at 1, 6, and 12 months. Mean MVG was measured by Doppler and MVA by planimetry and pressure half-time, and evaluated in a central core laboratory. Pre- and postclip deployment, simultaneous left atrial/pulmonary capillary wedge and left ventricular pressures were obtained in eight patients. RESULTS: Three patients did not receive a clip, six patients had their clip(s) explanted by 6 months (none for mitral stenosis), and four were repaired with two clips. Results are notable for a slight increase in mean MVG by Doppler postclip deployment (1.79 +/- 0.89 to 3.31 +/- 2.09 mm Hg, P < 0.01) and an expected decrease in MVA by planimetry (6.49 +/- 1.61 to 4.46 +/- 2.14 cm(2), P < 0.001) and by pressure half time (4.35 +/- 0.98 to 3.01 +/- 1.42 cm(2), P < 0.05). There were no significant changes in hemodynamic parameters postclip deployment by direct pressure measurements. There was no change in MVA by planimetry from discharge to 12 months (3.90 +/- 1.90 to 3.79 +/- 1.54 cm(2), P = 0.78). CONCLUSIONS: Echocardiographic and hemodynamic measurements after percutaneous mitral valve repair with the MitraClip show an expected decrease in mitral valve area with no evidence of clinically significant mitral stenosis either immediately after clip deployment or after 12 months of follow-up. 相似文献
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