单气囊小肠镜在小肠疾病诊断中的应用

目的评价单气囊小肠镜（SBE）在小肠疾病诊断中的安全性、检查范围及临床价值。方法对2009年6月至9月间行SBE检查的疑有小肠疾病患者的临床资料进行回顾性分析,总结检查完成情况、操作时间以及并发症发生情况等。结果30例患者共行35例次SBE检查。单纯经口检查15例;单纯经肛检查10例;经口＋经肛检查5例,均完成对接检查。共26例明确诊断,疾病检出率为86．7％（26／30）。经口进镜检查平均用时49．7min,经肛进镜检查平均用时48．6min。所有患者检查过程中生命体征处于安全范围,无心脑血管并发症发生,无剧烈腹痛及出血、穿孔等并发症出现。结论SBE是一种安全、可靠的检查手段,用于诊断小肠疾病具有较好的临床价值。     

双气囊内镜在诊断和治疗小肠疾病中操作难易性和安全性评价

目的探讨双气囊内镜在诊断和治疗小肠疾病中的难易性和安全性。方法2003年8月至2006年9月对196例患者进行双气囊内镜检查，观察其检查时间、操作成功率、全小肠检查成功率和并发症发生情况。结果单纯经口检查82例，平均耗时71min；单纯经肛检查52例，平均耗时99min；经口经肛联合检查62例，平均耗时159min。经口双气囊内镜144次，成功143次，操作成功率为99．3％，经肛检查114次，成功106次，操作成功率为93．0％。单纯经口或经肛均未能完成全小肠的检查，经口经肛联合检查完成3例全小肠检查。检查后发生声音嘶哑3例，黏膜下血肿1例，无死亡病例。结论双气囊内镜检查操作简单易学，成功率较高，其在小肠疾病诊治中的应用是安全可靠的，但是观察全部小肠尚有一定困难。     

单气囊小肠镜对可疑小肠疾病诊疗价值的探讨

背景:单气囊小肠镜(SBE)作为一种较新的小肠检查手段,在可疑小肠疾病中的临床价值需进一步探讨。目的:评价SBE在可疑小肠疾病诊疗中的价值。方法:回顾性总结2011年7月-2013年10月成都军区总医院接受SBE检查的73例患者共81例次检查的资料,分析SBE的适应证以及对可疑小肠疾病的诊断和治疗效果。结果:81例次SBE检查中,不明原因消化道出血33例次(40.7%),不全性肠梗阻29例次(35.8%),慢性腹痛或腹泻19例次(23.5%)。SBE经口插镜深度平均为230 cm,经肛平均为100 cm。SBE的阳性诊断率为67.9%,检出病变主要包括小肠溃疡、小肠炎症、小肠肿瘤和小肠息肉等。镜下治疗8例,其中止血治疗5例,息肉切除3例。无严重并发症发生。结论:SBE是可疑小肠疾病的有效诊疗手段,其主要适应证为不明原因消化道出血和不全性肠梗阻。     

单气囊内镜的临床应用价值初步探讨

目的初步评价单气囊内镜在小肠疾病诊治中的应用价值。方法回顾分析2009年2月-8月使用Olympus单气囊内镜检查23例临床怀疑小肠疾病患者的临床资料。接受检查患者包括消化道隐源性出血9例,腹痛7例,胶囊内镜检查发现可疑肿物4例,高度怀疑克罗恩病3例。结果23名患者共进行了34次单气囊内镜检查。内镜准备平均时间少于5min。经口途径的平均检查时间为（61±25）min,经肛途径的平均检查时间为（67±28）min。6名患者完成了全小肠检查。小肠病变的检出率为60．9％。无穿孔等严重并发症发生。结论单气囊内镜的准备及操作过程简单,而且能够安全的检查小肠。单气囊内镜可用于可疑小肠疾病的诊治。     

双气囊小肠镜对小肠出血的诊断价值

目的探讨双气囊小肠镜对小肠出血的诊断价值及安全性。方法对2007年1月-2008年12月我院经常规检查怀疑为小肠出血的56例患者行双气囊小肠镜检查,分别接受经口或经肛双气囊小肠镜检查。主要分析检查时间、内镜插入深度、确诊情况和并发症发生率。结果所有患者无严重并发症,操作时间为35-150 min,平均（76±22）min;平均插入小肠长度经口和经肛分别为（254±126）cm和（182±103）cm。小肠病变中阳性发现46例（82.1%）,主要包括血管畸形、小肠溃疡、克罗恩病、慢性非特异性炎症、肿瘤、息肉及憩室等。结论双气囊小肠镜检查安全有效,为小肠出血疾病的诊断提供了新的手段。     

双气囊小肠镜在68例小肠疾病诊断中的价值

目的 评价双气囊小肠镜对小肠疾病的诊断价值及安全性和耐受性.方法 2003年5月至2005年7月,对68例经常规检查无异常发现、疑患小肠疾病患者进行双气囊小肠镜检查,其中不明原因反复消化道出血39例、不完全性小肠梗阻7例、慢性腹痛14例、慢性腹泻8例.结果 68例患者中,36例经口进镜,25例经肛进镜,7例患者分别经口及经肛进镜检查.除3例因肠腔狭窄中止进镜外,其余病例均能检查1/2-3/4的小肠,7例患者结合经口及经肛途径完成全小肠检查.68例患者中41例检出阳性病灶,总阳性率为60.3%;其中不明原因消化道出血阳性率为62.6%（26/39）,不完全性小肠梗阻阳性5例,慢性腹痛阳性率为43%（6/14）,慢性腹泻阳性4例.除11例经口进镜者行异丙芬静脉全身麻醉外,其他经口及经肛进镜患者均能耐受整个检查,未出现出血、穿孔等严重并发症.结论 双气囊小肠镜是一种对小肠疾病诊断价值较高、安全可靠的检查手段.     

双气囊小肠镜对小肠疾病的诊断价值

目的评价双气囊小肠镜对小肠疾病的诊断价值。方法使用Fujinon双气囊小肠镜对我院2011年1月～2012年7月间拟诊小肠疾病的186例患者进行检查。43例患者经口进镜检查,69例患者经肛进镜检查,36例患者经口+经肛进镜检查。镜下可疑病变常规进行组织病理活检。结果 186例双气囊小肠镜检查共发现小肠病变164例,阳性率达88.2%。发现小肠肿瘤性病变28例(炎性息肉14例,间质瘤5例,黄色瘤5例,错构瘤1例,小肠腺癌1例,十二指肠恶性淋巴瘤1例,胃肠息肉病1例)。小肠炎症性病变108例,其中小肠克罗恩病17例,小肠非特异性炎症91例。小肠寄生虫病5例(包括钩虫、鞭虫)。小肠憩室13例,其中确诊小肠Meckels憩室出血1例。小肠外压性狭窄8例。小肠异物2例,均通过小肠镜异物钳成功取出异物。成功行回盲部溃疡出血小肠镜下钛夹止血治疗1例。尚未发生出血、穿孔、胰腺炎等并发症。结论双气囊小肠镜能安全、准确地检查全段小肠,并能对可疑病变取活检,明显提高了诊断的准确性及阳性率,对小肠疾病的诊断有很大应用价值。     

双气囊小肠镜对小肠出血的诊断价值研究

目的通过双气囊小肠镜对不明原因的小肠出血疾病进行病因分析。方法回顾性分析2008年10月至2014年1月我院应用双气囊小肠镜对小肠出血疾病患者进行检查,并分析消化道出血的病因组成。结果 163名患者接受173例次小肠镜检查,经口进镜检查59例次,经肛门进镜检查104例次,经口及经肛门两端进镜检查10例,检查成功率100%,其中阳性病例134例(77.46%),所有患者未发生出血、穿孔、梗阻等不良反应和相关并发症。结论小肠出血的病因诊断较困难,目前双气囊小肠镜是诊断小肠出血有价值、安全可靠的检查方法。     

双气囊小肠镜在治疗老年患者小肠疾病中的有效性与安全性

目的探讨双气囊小肠镜(DBE)在老年患者小肠疾病中的诊治作用及安全性。方法回顾性分析2014年1月至2014年12月在江苏省中医院消化内镜中心住院的24例年龄60岁的老年小肠疾病患者,男16例、女8例;年龄60~83岁(68.7±5.6)岁;行小肠镜诊治30例次,经口18例、经肛12例;全小肠检查4例,经口+经肛进镜2例。结果 24例行DBE检查共发现病变18例,阳性率75%;30例次检查中,6例次治疗、炎性病变4例、肿瘤占位性病变3例、出血性病变3例、息肉3例、淋巴管扩张1例、多发性憩室1例、间质瘤1例、克罗思病2例、检查阴性6例。6例次治疗中,3例行内镜黏膜下切除术(EMR),2例行镜下止血术,置小肠营养管1例;2例术后腹痛,无出血、穿孔并发症。结论双气囊小肠镜是老年患者小肠疾病诊疗的有效手段,且安全有效。     

双气囊电子小肠镜在小肠狭窄诊断中的作用

目的:比较双气囊电子小肠镜及小肠钡灌检查在疑有小肠狭窄患者中病变的检出率和诊断率,评价双气囊电子小肠镜在小肠狭窄诊断中的价值及安全性.方法:疑患小肠疾病患者76例,行双气囊电子小肠镜检查,分别经口或经肛进镜,对未检出病灶者建议择期改换进镜方式再行检查;其中疑小肠狭窄患者13例均行小肠钡灌检查.比较2种检查方法在疑小肠狭窄患者中病变的检出率、诊断率.结果:疑有小肠狭窄患者13例中有8例经口、3例经肛、2例分别经口和经肛行双气囊电子小肠镜检查,检查所用平均时间74(55-120)min,小肠狭窄病变检出率为84.6%(11/13),其中小肠肿瘤6例,克罗恩病3例,炎性狭窄2例.检出病变中双气囊电子小肠镜诊断率为69.2%(9/13),所有患者均未发生严重不良反应和并发症.疑小肠狭窄患者小肠钡灌检查的病变检出率为53.8%(7/13),其中小肠肿瘤3例,克罗恩病2例,炎性狭窄2例.在小肠钡灌检查未发现异常的6例病变中有4例在双气囊电子小肠镜检查中发现病变;3例未能正确诊断的病例在双气囊电子小肠镜检查中均得到正确诊断.双气囊电子小肠镜在小肠狭窄中的病变检出率和诊断率均明显高于小肠钡灌检查,二者均有显著差异(P<0.05).结论:双气囊电子小肠镜对小肠狭窄有较高的病变检出率和诊断率,无严重不良反应和并发症,可作为首选检查方法.     

单气囊小肠镜诊治疗小肠疾病的安全性及其临床价值观察

目的 评价单气囊小肠镜在小肠疾病诊治过程中的安全性及其临床应用价值.方法 回顾2009年4月至2010年7月间采用单气囊小肠镜榆查或治疗的83例患者的临床资料,对准备时间、检查时间、病变检出率及并发症发生率等情况进行总结分析.结果 83例患者包括不明原因消化道出血37例、不明原因慢性腹痛38例、慢性腹泻1例、不明原因发...     

Diagnostic yield and therapeutic impact of single-balloon enteroscopy: Series of 106 cases

Background and Aim:  Single-balloon enteroscopy (SBE) is a novel method of balloon assisted enteroscopy which allows deep intubation of intestine and has therapeutic potential. This prospective study was done in a tertiary care center to evaluate the feasibility, complications, diagnostic and therapeutic yield of SBE in patients with suspected small bowel disorders.
Methods:  One hundred and six patients (mean age 40.1 years, range 12–76 years, 65 men) with suspected small bowel diseases underwent 131 SBE procedures between February 2007 and July 2008.
Results:  Indications for SBE included obscure gastrointestinal bleeding (OGIB) (40), chronic abdominal pain with abnormal imaging studies (34), chronic diarrhea (20), polyposis syndromes (11) and foreign body (1).The mean insertion depth was 255.8 ± 84.5 cm beyond the duodenojejunal flexure by the oral route and 163 ± 59.3 cm proximal to the ileocecal valve by the per anal approach. The mean duration of the procedure for antegrade and retrograde enteroscopy was 65.9 ± 19.5 min and 72.3 ± 18.3 min, respectively. Pan-enteroscopy was possible in 25% of cases (five of 20 cases in which total enteroscopy was attempted). Diagnostic yields in cases of OGIB, chronic abdominal pain and chronic diarrhea were 60%, 65% and 55%, respectively. Overall new diagnosis was established in 46% and the extent of known disease was assessed in 15% of cases. In 21% of patients, therapeutic interventions were carried out while surgical treatment was directed to 8.4% of the patients. No major complications were observed.
Conclusion:  SBE is well tolerated and has good diagnostic yield, having a similar yield to previous double-balloon enteroscopy reports.     

单气囊小肠镜在小肠疾病诊断中的临床应用

背景:小肠镜的应用使观察完整的小肠成为可能,但目前关于单气囊小肠镜诊断小肠疾病的研究尚较少。目的:评价单气囊小肠镜对小肠疾病的诊断价值、安全性和患者耐受性。方法:对2009年2～9月上海新华医院收治的28例疑似小肠疾病患者行单气囊小肠镜检查,分析疾病检出率、操作相关并发症以及患者的耐受性。结果:本组经口进镜者9例,经肛门进镜17例,分别从两端进镜2例。检查操作时间40～100 min,平均(65.0±25.7)min。插管成功率96.4%。20例患者发现阳性病灶,检出率71.4%。所有患者均未发生操作相关并发症,耐受性良好。结论:单气囊小肠镜是一种对小肠疾病诊断价值较高、安全可靠的检查手段。     

双气囊小肠镜在不完全性小肠梗阻中的诊疗作用

目的:评价双气囊小肠镜(DBE)在诊断和治疗小肠不全性梗阻中的临床应用价值.方法:2004-04/2011-09,对107例不完全性小肠梗阻患者进行了DBE检查,并选择部分患者进行DBE镜下治疗.结果:107例不完全性肠梗阻患者共接受DBE检查189例次(经口检查122例,经肛门检查67例,其中双侧对接检查45例).共有98例明确了梗阻原因,诊断率为91.6%(98/107).对其中64例患者(56例为发现小肠巨大息肉的Peutz-Jeghers综合征患者,8例为良性小肠狭窄患者)共进行了175例次镜下治疗:包括小肠息肉切除167例次,扩张治疗8例次.50例患者(78.1%,息肉切除45例,扩张治疗5例)经内镜治疗后肠梗阻症状消失或缓解.189例次DBE检查或治疗过程中出现3例小肠穿孔,2例引起血色素下降的消化系出血,严重并发症发生率2.7%(5/189).结论:DBE对不完全性小肠梗阻患者具有较高的诊断率,并能对部分患者提供镜下治疗,避免了不必要的外科手术,在不完全小肠梗阻的诊断和治疗中具有重要临床应用价值.     

Double Balloon Enteroscopy–The Last Blind-Point of the Gastrointestinal Tract

Technical challenges have obstructed the diagnosis and treatment of small intestine disease. An innovative form of enteroscopy—the double balloon method—permits visualization of the complete small intestine, to-and-fro examination of an area of interest, and biopsy and endoscopic procedures which are safer, faster, and less painful than earlier methods. From October 2003 to May 2004, a total of 10 patients with obscure gastrointestinal bleeding received 12 enteroscopic examinations, 8 per oral and 4 per rectal examinations, while 2 patients received per oral enteroscopy first and further per rectal procedures 2 days later. Two cases with intestinal submucosal tumors were discovered by per oral enteroscopy, one with a 5-cm SMT with reddish mucosa at the jejunum and another with a 4-cm SMT and surface ulceration, in which the biopsy showed GIST. Both patients received an operation later. Four patients were found to have intestinal angiodysplasia in jejunum(per oral) and one in ileum (per rectal), and after local therapy bleeding stopped. Multiple angiodysplasias were observed in a patient who was operated on for active bleeding from the ileum after Indian ink tattooing. The two patients who received per oral and per rectal procedures did not display definite small intestinal lesions. All patients underwent the procedures satisfactorily without any complications, and the examination times varied from 90 to 360 min. Double balloon enteroscopy permits deep insertion of an endoscope into the small intestine without excessive stretching of the intestinal tract. This method can use either an oral or an anal approach. To-and-fro observation of almost the complete small intestine is possible, as are interventions.     

双气囊小肠镜的临床应用及评价

目的探讨双气囊电子小肠镜对小肠疾病的诊断价值及其安全性。方法对怀疑或证实有小肠疾病的156例患者进行小肠镜检查,经口检查22例,经肛门检查32例,双侧对接检查102例。结果小肠镜对小肠病变的阳性检出率为69.2%(108/156),小肠出血患者的病变检出率最高(83.3%),腹痛患者的病变检出率较低(51.7%),两组检出率相比差异有统计学意义(P<0.01)。肿瘤是小肠出血最多见的病因(25.0%),其次为憩室(19.4%)。黑便患者主要经口进镜检出(59.5%),鲜血便患者主要通过经肛进镜检出(74.3%),两者相比差异有统计学意义(P<0.01)。小肠镜检查无明显并发症出现。结论双气囊小肠镜检查成功率高,安全可靠,可作为小肠疾病诊断的首选方法。     

Capsule endoscopy and single-balloon enteroscopy in small bowel diseases: Competing or complementary?

AIM To evaluate diagnostic yields of capsule endoscopy(CE) and/or single-balloon enteroscopy(SBE) in patients with suspected small bowel diseases.METHODS Were trospectively analyzed 700 patients with suspected small bowel diseases from September 2010 to March 2016. CE, SBE, or SBE with prior CE was performed in 401, 353, and 47 patients, respectively. Data from clinical and endoscopy records were collected for analysis. Indications, procedure times, diagnostic yields, and complications were summarized and evaluated.RESULTS The overall diagnostic yield for the CE group was 57.6%. The diagnostic yield of CE in patients with obscure gastroin testinal bleeding(OGIB) was significantly greater than that in patients with no bleeding(70.5% vs 43.8%, P 0.01). The overall diagnostic yield of SBE was 69.7%. There was no difference in the diagnostic yield of SBE between patients with OGIB and those with no bleeding(72.5% vs 68.9%, P = 0.534). Forty-seven patients underwent CE prior to SBE. Among them, the diagnostic yield of SBE with positive findings on prior CE was 93.3%. In addition, SBE detected two cases with superficial ulcer and erosive lesions in the small bowel, which were missed by CE. However, one case with lymphoma and two with Crohn's disease were not confirmed by SBE. The rate of capsule retention was 2.0%. There were no significant complications during or after SBE examinations.CONCLUSION SBE is a safe and effective technique for diagnosing small bowel diseases. SBE with prior CE seemed to improve the diagnostic yield of small bowel diseases.