共查询到20条相似文献,搜索用时 0 毫秒
1.
David R Williams 《Movement disorders》2004,19(3):333-335
Recent criteria for the classification of palatal tremor use clinical, imaging, and electrophysiological features to differentiate essential and symptomatic forms. A case of probable psychogenic palatal tremor (PPT) is described within the context of these criteria, which lack clear guidelines for diagnosing PPT. The heterogenous nature of essential palatal tremor and its relationship with PPT, voluntary palatal movements, and tics is discussed. 相似文献
2.
Palatal tremor (formerly palatal myoclonus) is an extremely rare, but potentially treatable cause, of objective tinnitus.
The tinnitus is thought to be secondary to rhythmic involuntary movements of the soft palate. Its aetiology is variable and
it remains difficult to treat. Many different medical and surgical remedies have been tried but none have demonstrated reproducible
success. Botulinum toxin has been used in sporadic cases and seems to produce good results. Ten patients with palatal tremor
have presented to this department over the last three years. After discussion with the patients with regard to the management
of this condition and possible complications, five opted for botulinum toxin therapy and five declined further intervention.
Clinical diagnosis was made on the confirmation of soft palate movements synchronous with an audible clicking noise. Five
patients underwent botulinum toxin injection into the insertion of the levator and tensor veli palatini muscles. Of the five
that were treated with toxin, four showed complete resolution of symptoms after a course of treatment. Only one patient reported
transient side effects. This would suggest that botulinum toxin is a safe and effective first line treatment for palatal tremor. 相似文献
3.
Petra Schwingenschuh Karoline Wenzel Petra Katschnig Ronald Saurugg Erwin Ott 《Movement disorders》2007,22(5):742-745
We describe a case of a palatal tic resembling palatal tremor (PT) in a young female patient with a previously unrecognized mild Tourette syndrome. At the time of her visit, the patient complained about ear clicks that were audible to others. We discuss the differential diagnoses of hyperkinetic palatal movements emphasizing the ongoing discussion about essential PT representing a more heterogeneous disorder than previously thought. 相似文献
4.
Essential palatal tremor (EPT) may not be a uniform or single entity. We present two patients who had some "voluntary control" over EPT, including entrainment. We review the English language literature on EPT to describe a wider clinical spectrum of this syndrome. 相似文献
5.
Pramod Kumar Pal Ponnathpur Satish Lakshmi Muninarayanappa Nirmala 《Movement disorders》2007,22(10):1484-1486
We report the outcome of botulinum toxin injection for essential palatal myoclonus, given on two occasions over a period of one year, in an eight-year-old boy, the youngest patient treated with botulinum toxin to date. Though there was significant relief of ear clicks each time after the injection, he developed severe palatal palsy following the second injection, which persisted for a month. We suggest that appropriate caution needs to be exercised when repeating botulinum toxin injections for palatal myoclonus in children. 相似文献
6.
《Movement disorders》2006,21(2):274-276
We describe a case of psychogenic palatal tremor. The diagnosis was supported by clinical criteria and neurophysiological testing, including frequency analysis and jerk‐locked back‐averaging. We discuss the differential diagnosis of palatal tremor as well as the role of neurophysiological testing in the diagnosis of psychogenic movement disorders. © 2005 Movement Disorder Society 相似文献
7.
The clinical and electrophysiological features of a truncal myoclonus in a 55-year-old man are described. The electromyographic characteristics point toward propriospinal myoclonus. It is suggested that a myoclonic generator was released after use of ciprofloxacin, by antagonising the gamma-aminobutyric acid metabolism. 相似文献
8.
We describe a 16-year-old woman with an unusual clinical presentation of palatal myoclonus after a severe upper respiratory infection. Besides the postinfectious onset, this case is unique in that the rhythmical contractions of her oropharynx, larynx, and esophagus occur in couplets rather than single contractions of typical essential palatal myoclonus. Additionally, these contractions are present only during the inspiratory phase of respiration. Imaging and other diagnostic studies show no evidence of cerebellar or brainstem pathology. This case broadens the phenomenology of palatal myoclonus and illustrates the occasional overlap in clinical features between essential and symptomatic palatal myoclonus. 相似文献
9.
Tjeerd Mondria MD Henriëtte H.W. de Gier MD Agnita J.W. Boon MD PhD 《Movement disorders》2007,22(4):573-576
Lingual myoclonus is a poorly understood disorder that may occur in isolation or combined with palatal myoclonus. In this report, we present the case history of a 21-year-old patient with a therapy-resistant essential lingual and palatal myoclonus where a simple dental device was able to control symptoms. The use of this device will be highlighted and compared to previously described methods. Cases of previously recorded lingual and palatal myoclonus will be reviewed and compared to the case of our patient. 相似文献
10.
Dominic Thyagarajan Timothy Chataway Rong Li Wei Ping Gai Michael Brenner 《Movement disorders》2004,19(10):1244-1248
We report on a pedigree of dominantly-inherited, adult-onset Alexander disease caused by the glial fibrillary acidic protein (GFAP) gene mutation, R416W. This pedigree highlights the importance of genetic analysis of the GFAP gene in leukodystrophy with palatal tremor. 相似文献
11.
Idiopathic palatal myoclonus 总被引:1,自引:0,他引:1
T. Yokota F. Hirashima Y. Ito H. Tanabe T. Furukawa H. Tsukagoshi 《Acta neurologica Scandinavica》1990,81(3):239-242
Two cases with idiopathic palatal myoclonus without other neurological deficits were described. They did not have any other neurological deficits other than myoclonus of branchial muscles. In these cases, the myoclonus disappeared during natural or induced sleep. In Case 1, the myoclonus ceased transiently when the patient was calculating or receiving an injection. In Case 2, the myoclonus disappeared with intravenous injection of saline as a placebo. Detailed examinations, including brain CT, MRI and multiple evoked potentials, showed normal results. The myoclonus in Case 2 disappeared after we had explained that her disease was benign. Since the clinical features and laboratory data in idiopathic palatal myoclonus are quite different from those in palatal myoclonus with other neurological deficits, idiopathic palatal myoclonus is considered to be a separate syndrome. Invasive examinations or excessive medications should be avoided because of its benign prognosis. 相似文献
12.
Espen Dietrichs Mona Skard Heier Hilde Faye-Lund Per H Nakstad 《European journal of neurology》1999,6(3):367-370
A 40-year-old woman with myoclonic contractions bilaterally in the infrahyoid neck muscles, especially in the left cricothyroid muscle, was presented and successfully treated with botulinum toxin injections. The patient had a wide, aberrant vessel curving into the left dorsolateral reticular formation of the medulla oblongata. Based on our observations, we propose that symptomatic bulbar and palatal myoclonus is caused by pathology in the dorsolateral reticular formation, and not by inferior olivary dysfunction as is currently thought. 相似文献
13.
Frédéric Bourdain Emmanuelle Apartis Jean-Marc Trocello Jean-Sébastien Vidal Pascal Masnou Laurent Vercueil Marie Vidailhet 《Movement disorders》2006,21(5):599-608
Familial cortical myoclonic tremor (FCMT) is a rare disorder often leading to a wrong clinical diagnosis of essential tremor. Electrophysiological data are usually considered to allow a correct diagnosis. We describe a FCMT French family with previously unreported clinical features such as sensitivity to glucose deprivation, vibration, repetitive visual patterns, and intense visual or auditory stimulation and contrasts. Electrophysiological studies of the propositus confirm the cortical reflex myoclonus elicited by photic stimulation and the absence of epileptic electroencephalographic discharges. We emphasize that a precise clinical analysis can lead to a correct diagnosis before electrophysiological confirmation. This is also the first-ever report of efficacy of levetiracetam in FCMT. 相似文献
14.
Andrew F. Gao MD Achinoam Faust‐Socher MD Maryam Al‐Murshed MD Marc R. Del Bigio MD PhD Anthony E. Lang MD David G. Munoz MD MSc 《Movement disorders》2017,32(10):1465-1473
Background: Sporadic progressive ataxia and palatal tremor is a rare syndrome characterized by mid‐ to late‐adult‐onset symptomatic palatal tremor and slowly progressive cerebellar ataxia. To date, there has been only one autopsy report, which described a novel 4‐repeat tauopathy with hypertrophic olivary degeneration and tau‐positive inclusions in olivary neurons and dystrophic neuritic processes termed glomeruloid bodies. We report on 2 additional autopsy cases. Methods: Sections from selected paraffin‐embedded brain regions were stained with hematoxylin and eosin/Luxol fast blue and processed for phosphorylated tau, 3‐repeat tau, 4‐repeat tau, neurofilament, glial fibrillary acid protein, phosphorylated α‐synuclein, phosphorylated TAR DNA‐binding protein 43, beta‐amyloid, and p62 immunohistochemistry. Results: Two male patients were aged 74 and 64 years at onset. Both had clinical findings consistent with progressive ataxia and palatal tremor and T2 hyperintensity in the bilateral olives on MRI. Pathological findings included bilateral hypertrophic olivary degeneration accompanied by glomeruloid bodies, 3‐repeat and 4‐repeat tau‐positive neuronal inclusions in the olive, and additional tauopathy in the midbrain, pons, and thalamus. Cerebellar cortical degeneration was extensive, but involvement of the dentate was minimal. P62‐positive, but tau‐ and TAR DNA‐binding protein 43–negative, inclusions in the cerebellum of 1 case was also a feature. Conclusions: Whereas our findings are largely in keeping with the previously published case report, we found a more extensive and mixed 3/4‐repeat tauopathy and additional cerebellar p62 pathology, highlighting our incomplete understanding of the pathogenesis of this disease. © 2017 International Parkinson and Movement Disorder Society 相似文献
15.
Anne-Fleur van Rootselaar Natasha M Maurits Johannes H T M Koelman Johannes H van der Hoeven Lo J Bour Klaus L Leenders Peter Brown Marina A J Tijssen 《Movement disorders》2006,21(2):215-222
Familial cortical myoclonic tremor with epilepsy (FCMTE) is characterized by a distal kinetic tremor, infrequent epileptic attacks, and autosomal dominant inheritance. The tremor is thought to originate from the motor cortex. In our patient group, a premovement cortical spike could not be established on electroencephalogram (EEG) back-averaging. Corticomuscular and intermuscular coherence analysis can demonstrate a cortical common drive to muscles. We carried out coherence analysis of electromyography (EMG) of forearm muscles and EEG of contralateral motor cortex in 7 FCMTE patients, 8 essential tremor (ET) patients, and 7 healthy controls. Results showed strong cortico- and intermuscular coherence in the 8- to 30-Hz range in the FCMTE patients, with EEG preceding EMG. Healthy controls and ET patients showed normal weak coherence around 20 Hz. The ET patients showed some additional coherence at tremor frequency (6 Hz), probably the result of sensory information flowing back to the sensorimotor cortex. These findings point to a pathological cortical drive in FCMTE patients leading to tremulous movements. Coherence analysis is an easy and useful method to differentiate FCMTE from ET. Coherence analysis is helpful when investigating a cortical common drive in cortical tremor and other movement disorders. 相似文献
16.
Katherine L. Howard MS Deborah A. Hall MD Michelle Moon MD Pinky Agarwal MD Elizabeth Newman Michael Brenner PhD 《Movement disorders》2008,23(1):118-122
A novel glial fibrillary acidic protein (GFAP) mutation, Y257C, is reported in a patient with adult‐onset Alexander disease. This is the oldest reported case with confirmation of a GFAP mutation. Onset was late in the sixth decade. Genetic analysis of the GFAP gene is recommended in cases of progressive ataxia and palatal tremor. © 2007 Movement Disorder Society 相似文献
17.
J. De Bleecker W. van Landegem L. Crevits J. De Reuck 《Acta neurologica Scandinavica》1992,85(2):150-153
A 23-year-old man suffered from palatal myoclonus for 2 years. It had appeared one week after a minor head trauma. MRI and basal cisternography revealed a localized atrophy of the left paramedian part of the medulla, encroached upon the left vertebral artery. Clonazepam treatment was beneficial. This particular case is discussed in relation to etiopathogenesis and other causes of palatal myoclonus. 相似文献
18.
Anne-Fleur van Rootselaar Eleonora Aronica Ernst N H Jansen Steur Johanna M Rozemuller-Kwakkel Rob A I de Vos Marina A J Tijssen 《Movement disorders》2004,19(2):213-217
The clinical and neuropathological findings in a patient with familial cortical tremor with epilepsy (FCTE) are described. Clinically, the patient showed cortical myoclonus, tremor, and generalized seizures. Pathological investigation showed cerebellar degeneration and somal sprouting and loss of dendritic tree in Purkinje cells. Striking similarities were found in diseases caused by channelopathies such as spinocerebellar ataxia subtype 6. 相似文献
19.
20.
Summary Palatal myoclonus associated with extremity movements such as myoclonus or tremor is uncommon and reports are rare. Five patients with palatal myoclonus and a rest tremor are presented. In four patients, a slow rest tremor (3 Hz or less) was present. The tremor persisted on sustained posture and finger-to-nose maneuvers and was usually not synchronous with the palatal movements. It was not associated with clinical manifestations of Parkinson's disease and occurred in conjunction with brain-stem infarction in three patients. 相似文献