Impact of cyclosporine on cadaveric renal transplantation: a summary statement

CsA has now been used in this country for about four years and has been widely available for a little more than one year. Both the experience of those centers that have been using it longest, and total US national experience, suggest that CsA is now, with the sole exception of recipients matched for both HLA-DR antigens, the immunosuppressive of choice for all cadaveric renal allografts, conferring approximately a 10% advantage in graft survival. The advantages of CsA seem particularly apparent in the management of high-risk patients such as those over 50 years old and those with diabetes. CsA appears to reduce the frequency of rejection episodes and to permit reduction of steroid dosage. These factors, together with the improved graft survival rate, may contribute to a substantially higher rate of patient rehabilitation. The role of transfusion and HLA matching in association with CsA remains somewhat controversial. While large multicenter studies show the continued importance of both transfusion and optimal HLA matching, it has been argued that avoidance of pretransplant transfusions has avoided presentation of potential recipients, and that simplification of matching requirements has saved money and has permitted speedier transplantation of patients, favoring improved rehabilitation. Careful monitoring of the experience with this major new immunosuppressive agent over the next several years may answer these remaining questions.     

腹腔镜胆囊切除术1 660例临床总结

目的:探讨LC并发症预防及处理。方法:总结1997年12月~2004年3月,1660例LC患者手术方法、发生并发症原因、并发症预防及治疗资料。结果:1660例全部治愈,无死亡病例,并发症26例,其中胆漏12例,出血12例,过敏性休克2例,中转开腹38例,置腹腔引流管83例。结论:规范手术操作是减少并发症的基础,重视并发症的预防及正确处理是提高手术成功率的关键,正确把握中转手术指征及放置腹腔引流管是成功开展腔镜手术的重要措施。     

Clinical consensus statement: Diagnosis and management of nasal valve compromise

Objective

To create a clinical consensus statement to address ambiguities and disparities in the diagnosis and management of nasal valve compromise (NVC).

Subjects and Methods

An updated systematic review of the literature was conducted. In addition, a Modified Delphi Method was used to refine expert opinion and facilitate a consensus position.

Results

After two rounds of surveys and conference calls, 36 items reached consensus, six items reached near consensus, and 10 items reached no consensus. The categories that had the greatest percentage of consensus or near consensus items were as follows: definition, history and physical examination, outcome measures, and management. Conversely, the categories with greater percentage of no consensus items were adjunctive tests and coding.

Conclusion

The consensus panel agreed that NVC is a distinct clinical entity that is best evaluated with history and physical examination findings. Endoscopy and photography are useful but not routinely indicated, whereas radiographic studies are not useful in evaluating NVC. Other objective nasal outcome measures may not be useful or accepted for NVC. Nasal steroid medication is not useful for treatment of NVC in the absence of rhinitis, and mechanical treatments may be useful in selected patients. Surgical treatment is the primary mode of treatment of NVC, but bill coding remains ambiguous and confusing.     

腹腔镜辅助下治疗儿童脐尿管异常的临床总结

【摘要】 目的 总结腹腔镜辅助治疗脐尿管异常的临床经验。方法 回顾分析2006年1月至2012年12月我科开展腹腔镜辅助治疗脐尿管异常20例患儿的临床资料。结果 全部手术均顺利完成,无1例中转开腹手术,手术时间为45~90 min,平均60 min,术中出血3~5 mL,创伤小,无明显手术疤痕,术后5~7天出院,随访未发现复发及粘连性肠梗阻,疗效满意。结论 腹腔镜辅助治疗脐尿管异常是一种创伤小、美观、术后恢复快、安全有效的治疗方法。     

儿童误食磁性异物致消化道损伤的临床经验总结

目的:探讨儿童误食磁性异物致消化道损伤的临床特点、致病机制及诊治方法,为临床决策提供理论依据。方法:回顾性分析2017年10月—2021年9月安徽省儿童医院收治的46例消化道磁性异物患儿的临床资料,根据是否存在消化道穿孔将患儿分为消化道穿孔组( n＝28)和消化道未穿孔组( n＝18)。观察患儿...     

仙灵骨葆胶囊治疗骨质疏松症128例临床总结

目的探讨仙灵骨葆胶囊治疗骨质疏松症的疗效。方法 选择骨质疏松症患者128例,口服仙灵骨葆胶囊3粒/次,2次/天,计算总有效率。结果仙灵骨葆胶囊治疗骨质疏松症总有效率为86.7%。结论 仙灵骨葆胶囊治疗骨质疏松症效果显著。