自体巩膜包裹羟基磷灰石义眼座反向植入并斜肌缝合术

目的 探讨眼球摘除后自体巩膜包裹羟基磷灰石义眼座反向植入并斜肌缝合术的临床效果.方法 对64例眼球摘除自体巩膜包裹羟基磷灰石义眼座反向植入并斜肌缝合术.结果 64例术后结膜均Ⅰ期愈合,结膜囊宽阔光滑,义眼活动良好,外观良好.结论 羟基磷灰石具有良好的生物相容性,排斥反应低,自体巩膜包裹羟基磷灰石义眼座反向植入并斜肌缝合使义眼座得以双层巩固,提高了手术成功率.     

羟基磷灰石义眼座植入联合结膜囊成形改良术疗效观察

目的 观察羟基磷灰石义眼座植入联合结膜囊成形改良术的效果。方法 23例（23只眼）眼球严重损害伴部分结膜囊缩窄患者,在对其进行眼内容物摘除、羟基磷灰石义眼座植入的同时联合结膜囊成形改良术。结果 23例结膜囊狭窄患者手术全部成功,结膜囊成形良好,未见并发症。结论 对部分结膜囊缩窄患者,可在羟基磷灰石义眼座植入的同时行结膜囊成形改良术。     

羟基磷灰石义眼座植入同期结膜囊缩窄成形术

目的 观察羟基磷灰石义眼座植入同时结膜囊成形的效果。方法 19例眼球严重损害同时伴部分结膜囊缩窄19眼。在眼内容摘除，羟基磷灰石义眼座植入的同时行唇粘膜移植结膜囊成形术。结果 全部19眼唇粘膜移植成功。结膜囊成形良好，未见并发症。结论 对部分结膜囊缩窄患者，可在羟基磷灰石义眼座植入的同时行结膜囊成形术。     

改良唇粘膜移植结膜囊成形联合Ⅱ期羟基磷灰石义眼座植入术

目的 探讨同期唇粘膜移植结膜囊成形联合Ⅱ期羟基磷灰石义眼座植入术的手术方法及临床效果。方法 对16例眼球摘除术后结膜囊缩窄患者行改良唇粘膜移植结膜囊成形联合Ⅱ期羟基磷灰石义眼座植入术，观察术后眼窝内陷矫正、结膜囊成形及移植唇粘膜愈合情况，义眼座有无外露、感染及活动度。结果 移植唇粘膜全部成活，眼窝内陷基本矫正，眼座无外露，患者满意。结论 改良有唇粘膜移植结膜囊成形联合Ⅱ期羟基磷灰石义眼座植入术是治疗眼球摘除术后眼窝内陷、结膜囊缩窄的理想方法。     

Ⅱ期眼窝凹陷及结膜囊狭窄的联合整复手术

目的 探讨眼球摘除或眼内容物剜出术后眼窝内陷伴结膜囊狭窄的同期整复手术方法及临床疗效。方法 对2007年8月至2010年5月收治35例患者施行Ⅱ期义眼座植入联合结膜囊成形术,其中7例结膜囊轻度缺损采用下、上穹窿结膜划开;23例结膜囊中度缺损采用异体巩膜;5例结膜囊重度缺损采用自体唇粘膜移植。所有病例结膜囊内眼模支撑,轻、中度组行睑缘临时缝合,术后1月拆线,自体唇黏膜移植组行部分睑缘粘连术,术后3个月分开眼睑,试装义眼。观察术后眼窝内陷矫正、结膜囊成形情况。随访3～6月。结果 术后所有患者眼窝内陷明显改善,结膜囊成形良好,穹窿深浅可,均可配戴适合的义眼,活动度可。结论 Ⅱ期义眼座植入联合结膜囊成形术是治疗眼球摘除或眼内容物剜出术后眼窝内陷伴结膜囊狭窄的理想手术。     

Ⅱ期义眼座直接植入联合新鲜羊膜移植治疗眼窝内陷结膜囊狭窄

目的探讨Ⅱ期义眼座直接植入、新鲜羊膜移植治疗眼球摘除术后眼窝内陷、结膜囊狭窄的手术方法及手术间隔时间.方法对2000-04/2003-04收治眼球摘除术后出现眼窝内陷、结膜囊狭窄患者21例行Ⅱ期羟基磷灰石义眼座直接植入治疗眼窝内陷,1mo后行新鲜羊膜移植治疗结膜囊狭窄.观察术后义眼活动度、结膜囊成形情况,义眼配戴情况.结果21例患者H期羟基磷灰石义眼座直接植入后义眼活动度＞0.5cm,眼窝内陷明显好转;1mo后行新鲜羊膜移植治疗后结膜囊成形良好,深浅正常,临时义眼配戴后无脱落,活动尚可.无义眼座暴露及脱出,无新鲜羊膜溶解及排斥反应发生.结论Ⅱ期义眼座直接植入联合新鲜羊膜移植是目前治疗眼球摘除术后出现眼窝内陷、结膜囊狭窄的理想方法.     

前部巩膜覆盖羟基磷灰石义眼座植入术临床观察

羟基磷灰石义眼座植入术是目前改善眼球摘除术后眼窝畸形广泛采取的治疗方法.我院对47例眼球摘除患者行前部巩膜覆盖羟基磷灰石义眼座植入术取得理想效果,报告如下.     

羟基磷灰石义眼座在儿童应用的临床报告

目的研究羟基磷灰石义眼座在儿童应用的必要性及安全性。方法采用新型假体材料－羟基磷灰石义眼座对眼球摘除的16例患儿分别行一期或二期植入，分析植入的羟基磷灰石义眼座的直径大小及与眼球摘除时间、患者年龄等的关系。结果16例手术均术后一期愈合，无感染、伤口裂开等并发症。植入物的直径大小与患儿的年龄、眼球摘除时间及结膜囊内是否安装义眼有密切关系。结论在儿童期行眼球摘除术后应一期植入义眼座，以保证眼眶骨的正常发育。同时，应该选用具有良好的生物及组织相容性的羟基磷灰石义眼座。     

Medpor义眼座植入术矫正眼窝凹陷畸形临床观察

目的探讨多孔聚乙烯义眼座(M edpor)植入矫正眼窝凹陷畸形手术效果。方法 55例(55只眼)包括眼球萎缩、眼球摘除术后、眼内容摘除术后及合并结膜囊狭窄的患者,随机植入M edpor义眼座或羟基磷灰石义眼座,随访观察术后义眼座暴露、感染等并发症情况,比较手术疗效。结果 Medpor义眼座与羟基磷灰石义眼座能取得相同的良好的治疗效果,但前者并发症更少。结论 Medpor义眼座植入术疗效可靠,Medpor具有良好的组织相容性,是矫正眼窝凹陷畸形的理想材料。     

羊膜移植治疗义眼座植入术后结膜裂开伴结膜囊狭窄

目的:探讨羊膜移植治疗羟基磷灰石义眼座植入术后结膜裂开伴结膜囊狭窄的临床效果。方法:羟基磷灰石义眼座植入术后结膜裂开伴结膜囊狭窄患者16例16眼,手术松解结膜张力后,行保存羊膜移植于巩膜暴露区。结果:所有患者中,15例术后结膜愈合完全遮盖巩膜,结膜囊恢复理想深度;1例失败。结论:保存羊膜移植是治疗义眼座植入术后结膜裂开、保持理想结膜囊深度的有效方法。     

合并成型性渗出的急性前葡萄膜炎与HLA-B27的相关性研究

目的 探讨急性渗出性前葡萄膜炎与HLA-B27的相关性。方法 对53例前房内出现成型性渗出的急性前葡萄膜炎（AAUPE）患者及61例前房内无成型性渗出的急性前葡萄膜炎（AAU）患者进行HLA-B27的检测,并结合临床表现加以分析。结果 成型性渗出的AAUPE患者的HLA-B27阳性率为100％,而无成型性渗出的AAU患者的HLA-B27阳性率仅为50.8％。二者有显著差异性（P<0.01）。两组HLA-B27阳性的病人强直性脊柱炎发生率分别为50.0％和42.9％。结论 结果进一步证实了HLA-B27与成型性渗出密切相关的论点。提示检测AAU患者HLA-B27的阳性率,发现成型性渗出裂隙灯检查似与血清法检测同样准确。     

The efficacy of treating patients with intraocular hemorrhages with emoxypin

Emoxipin, a home-made preparation approved by the Pharmacological Committee for clinical usage in 1986, is a retinal protector. Its usage is indicated for treatment of chorioretinitis, diabetic retinopathy, thrombosis of retinal vessels as well as to protects the retina from a damaging action of light of high intensity. In order to study therapeutic effectiveness of emoxipin in intraocular hemorrhages of different genesis, the preparation was used subconjunctivally, 0.5 ml of a 1% solution daily for 10-15 days. Emoxipin was used in 29 patients (29 eyes) with intraocular hemorrhages, of them, due to contusion of the eye--in 19, hypertonic disease--in 6, thrombosis of the central retinal vein--in 2, after intraocular operations--in 2 patients. As a result of the treatment, partial or almost total resolution of hemorrhages and a rise of visual acuity of different degree were recorded in all patients. Before treatment, visual acuity was from light perception to 0.04 in 26 eyes, from 0.09 to 0.3 in 3 eyes. After treatment, it rose to 0.1-0.2 in 12 eyes, to 0.3-1.0--in 17 eyes.     

A case of hypertensive keratouveitis with endotheliitis associated with cytomegalovirus

AIM: While cytomegalovirus is well known as a pathogenic organism of retinitis, especially associated with human immunodeficiency virus infection, there are few reports of anterior uveitis associated with cytomegalovirus. METHODS: The authors present a case of keratouveitis associated with cytomegalovirus. RESULTS: A 70-year-old Japanese man was referred to the authors because of poorly controlled hypertensive keratouveitis in the left eye. The patient had a history of recurrent hypertensive anterior uveitis. At presentation, the corneal stroma was edematous, with Descemet's folds and pigmented keratic precipitates. The anterior chamber angle was depigmented compared to the fellow eye. Even though pupil dilation and posterior synechiae were absent, iris atrophy was not evident. His right eye appeared normal except for moderate cataract. Funduscopy of the left eye was hazy, with the optic disc showing a normal color but poorly defined details, and no apparent exdative retinitis. The best-corrected decimal visual acuity of the right and left eyes was 0.4 and 0.02, respectively. Intraocular pressure was 11 mmHg in the right eye and 35 mmHg in the left, despite maximum medical therapy. Systemic acyclovir and prednisolone for a month did not improve the hypertensive keratouveitis. The aqueous humor was investigated for herpes simplex virus, varicella-zoster virus and cytomegalovirus. Cytomegalovius genome was detected by polymerase chain reaction analysis. Oral valganciclovir rapidly reduced ocular hypertension within a week. CMV DNA disappeared 3 months after the initiation of valganciclovir. CONCLUSION: The authors reported a case of hypertensive keratouveitis with endotheliitis associated with cytomegalovirus.     

Angiolymphoid hyperplasia with eosinophilia of the eyelid with spontaneous regression

A 53-year-old Chinese man presented with a painless left upper eyelid lump of 2 weeks' duration. Histopathology was consistent with angiolymphoid hyperplasia with eosinophilia, and also revealed neutrophilic infiltrate secondary to ulceration. After incisional biopsy, the residual lesion, which was not treated, developed surface keratinization over the next 2 weeks and sloughed off, leaving intact epidermis and no scar. This case illustrates that observation awaiting spontaneous regression may be considered prior to surgical and other therapeutic interventions. The authors also briefly review the literature on angiolymphoid hyperplasia with eosinophilia and Kimura disease, with emphasis on ocular involvement.