Management of retained intravitreal lens fragments after cataract surgery.

With the rise of popularity of phacoemulsification as the preferred surgical method for cataract extraction, there has been an increased incidence of posterior dislocation of lens fragments. The appropriate management of this complication both during and after cataract extraction is discussed in this review. It is suggested that vigorous attempts by the cataract surgeon to retrieve intravitreal lens fragments should be avoided. Timely referral to a posterior segment surgeon for pars plana vitrectomy and removal of lens fragments can result in good visual outcome. Complications, such as glaucoma and retinal detachment, may develop in some cases. The importance of careful clinical follow-up is emphasized.     

Vitreoretinal surgery for retained lens fragments after phacoemulsification

PURPOSE: To evaluate the prognostic factors, effect of timing and outcomes of vitreoretinal surgery for removal of retained lens fragments after phacoemulsification. METHODS: A retrospective review of 43 eyes of 43 patients who had vitreoretinal surgery for retained lens fragments after phacoemulsification, between January 1998 and November 2000. RESULTS: Seven of the 43 patients underwent vitrectomy on the same day as cataract surgery, 20 in the first week, and 23 after the first week, with a mean of 14.8 days (0-90). Initial visual acuity was < or = 20/400 in 27 (75%, n=36) and intraocular pressure (IOP) > or = 25 mmHg in 22 (61%, n=36) eyes with or without medication. The mean preoperative IOP was 27.4 mmHg. Initial ocular findings included moderate or severe corneal edema in 17 patients (40%), uveitis in 14 (33%), retinal detachment in 1 (2%) and vitreous hemorrhage in 2 (5%). After a mean follow-up of 8.4 months, final best-corrected visual acuity (BCVA) was > or = 20/40 in 24 patients (56%) and < or = 20/400 in 7 (16%). Persistent corneal edema (one eye), cystoid macular edema (four eyes), age-related macular degeneration (one eye) and suprachoroidal hemorrhage (one eye) were the causes of BCVA < or = 20/400. Final mean IOP was 15.2 mmHg and only one case had IOP > 25 mmHg. Uveitis disappeared in all cases (p<0.001), and corneal edema persisted in only one eye. Both the BCVA and IOP differences were significant (p<0.001), but no correlation was found between pre- and postoperative BCVA and IOP as regards vitreoretinal surgery timing, posterior or anterior removal sites and IOL implantation sites or procedures. CONCLUSIONS: Vitreoretinal surgery is effective for removing retained lens fragments after phacoemulsification, lowering the IOP and reducing the uveitic reaction and corneal edema. BCVA > or = 20/40 can be reached in at least half the patients.     

Pars plana vitrectomy in the management of retained intravitreal lens fragments after cataract surgery

Purpose: To assess the outcome of patients who underwent pars plana vitrectomy for retained lens fragments after cataract surgery. Methods: A retrospective study of all consecutive cases with pars plana vitrectomy performed for retained lens fragment was conducted. Twenty‐seven eyes of 27 patients were included in the study. Results: Twenty‐four (89.9%) eyes received phacoemulsification. Pars plana vitrectomy was performed at the same sitting, or ranged from day 1?70 after cataract surgery. The mean follow up was 31.1 months. Final visual acuity of 6/12 or better was achieved in 15 (55.6%) patients. After excluding patients with pre‐existing eye diseases, 68.4% of patients had visual acuity 6/12 or better. Complications after pars plana vitrectomy included glaucoma (22.2%), retinal detachment (11.1%) and surgically induced necrotizing scleritis (3.7%). Conclusion: Ocular complications with poor visual outcome can occur after removal of intravitreal retained lens fragments complicating cataract surgery.     

Retained intravitreal lens fragments after phacoemulsification: a clinicopathological correlation

AIMS: To explore the relation between clinical course and timing of vitrectomy with the nature and intensity of intraocular inflammatory response in eyes with retained intravitreal lens fragments following complicated phacoemulsification. METHODS: Prospective evaluation of 22 eyes with retained lens fragments with emphasis on corneal clarity, uveitis, intraocular pressure (IOP), timing of vitrectomy, and visual outcome. Numbers of different types of inflammatory cells in vitreous washings were counted, masked to clinical details, in three non-overlapping adjacent high power fields. Relations between clinical and pathological findings were assessed. RESULTS: The IOP was raised in 19 eyes before vitrectomy and remained high in nine postoperatively. The latter had higher median total cell count (104 cells/mm(2)) than those with normal postoperative IOP (37 cells/mm(2)) but this difference was not statistically significantly different (p=0.17). Nine of 22 eyes underwent vitrectomy within 1 week of cataract surgery. Median total cell count in these eyes was 20 cells/mm(2) compared with 140 cells/mm(2) in eyes vitrectomised later-this difference was statistically significant (p <0.001). Final visual acuity was 6/12 or better in 13 eyes, these had fewer intravitreal inflammatory cells than the remaining six with poor visual outcome and no pre-existing cause for this (three patients excluded) (p=0.02). Macrophages were the predominant inflammatory cell type. CONCLUSION: There was significantly less inflammatory cell activity in eyes which had retained lens fragments removed early (within 1 week). Later removal was associated with persistently elevated IOP and poorer visual outcome.     

Vitrectomy for retained lens fragments in the vitreous after phacoemulsification

PURPOSE: To assess the visual results, retinal detachment (RD) rate, incidence of glaucoma, and intraocular lens (IOL) placement after vitrectomy for removal of retained lens fragments in the vitreous after phacoemulsification. SETTING: Department of Ophthalmology, University Hospital of Lund, Lund, Sweden. METHODS: This retrospective noncomparative interventional case series included all cases of pars plana vitrectomy for removal of retained lens fragments from January 1997 through January 2000. RESULTS: Sixty-six eyes of 65 patients had pars plana vitrectomy with removal of the lens material over the 3-year period. Visual acuity on presentation was 0.1 or worse in 36 eyes (54%). Visual acuity after vitrectomy was 0.5 or better in 35 eyes (53%). The postoperative visual acuity was worse than 0.1 in 14 eyes (21%). Twenty-seven (56%) of the 48 eyes operated on within 1 week and 8 (44%) of the 18 eyes operated on later achieved a visual acuity of 0.5 or better. Twelve eyes (80%) that had secondary posterior chamber IOL implantation achieved an acuity of 0.5 or better. An RD occurred in 7 eyes (11%). CONCLUSIONS: There was no statistically significant difference in outcomes between those having vitrectomy the first few days after cataract surgery and those having it later, although there was a trend toward better results when the vitrectomy was done sooner. Secondary IOL implantation resulted in a good visual outcome. Retinal detachment was the most severe complication.     

Retained intravitreal lens fragments after cataract surgery.

PURPOSE: The purpose of this study is to review the possible benefits and complications of vitrectomy for retained lens fragments after cataract surgery. METHODS: The authors reviewed the charts of 65 patients referred over a 12-year period for retained lens fragments after cataract surgery. Of these, 56 underwent vitrectomy and 9 were followed. Of these 56 eyes, 29 (52%) had received an intraocular lens (IOL) at the time of cataract surgery. RESULTS: Resulting complications from retained lens material included glaucoma (52%), corneal edema (46%), uveitis (56%), and decreased vision (100%). These sequelae responded equally to vitrectomy in eyes with or without an IOL and irrespective of type of cataract surgery (phacoemulsification or extracapsular cataract extraction). The timing of surgery did not statistically influence the final vision or the incidence of glaucoma. CONCLUSION: Removal of retained lens fragments allows rapid visual restoration, enhances resolution of uveitis, and improves control of glaucoma. Insertion of an IOL at the time of cataract surgery in the face of dislocated lens fragments is not contraindicated provided that it could be performed safely.     

Retrocapsular lens fragments after uneventful phacoemulsification cataract surgery

PURPOSE: To analyze the factors influencing the risk for lens fragments in the retrocapsular space after uneventful phacoemulsification cataract surgery. Setting: Norfolk and Norwich University Hospital, Norwich, United Kingdom. METHODS: Five hundred six consecutive patients who had uneventful phacoemulsification cataract surgery were examined intraoperatively for lens fragments in the retrocapsular space. Data collected for each patient included site of corneal incision, axial length, cataract nuclear density, phaco power and duration, and equivalent phaco time (EPT, calculated as a product of phaco power and duration). Statistical analysis was performed to determine the effect of each factor on the risk for developing retrocapsular lens fragments. RESULTS: Retrocapsular lens fragments were present in 16.6% of patients. Univariate analysis showed that the duration of phacoemulsification and EPT were significantly longer in patients with retrocapsular lens fragments than in those without. Logistic regression showed that EPT was the only factor statistically significantly associated with the fragments. However, the effect of EPT on the odds ratio of developing fragments was small. CONCLUSIONS: Lens fragments in the retrocapsular space occurred relatively frequently after uneventful phacoemulsification surgery. There was a small but statistically significant relationship between EPT and the risk for lens fragments.     

超声乳化致晶体碎块坠入玻璃体腔的手术治疗

目的评价玻璃体切除术治疗晶体坠落物的效果。方法对１９９２年１０月至１９９５年１０月澳大利亚墨尔本皇家维多利亚眼耳医院所做５８例玻璃体切除术治疗晶体坠落物的病例,随访３个月以上资料进行回顾分析。结果最后随访时残留囊样黄斑水肿３例（５．２％）,视网膜脱离２例（３．４％）,低眼压ｌ例（１．７％）,其余并发症均消失。其中３８只眼（６５．５％）最后视力≥０．５,仅６只眼视力＜０．０５。结论白内障手术中一旦发生晶体成分坠落于玻璃体内,宜妥善处理眼前段,可能时植入人工晶体,并尽快行玻璃体切除术治疗,一般可取得良好效果     

Clinical features and outcomes of pars plana vitrectomy in patients with retained lens fragments after phacoemulsification

PURPOSE: To review the clinical features and outcomes of pars plana vitrectomy (PPV) in patients with retained lens fragments after phacoemulsification and compare the results with those in previous studies. SETTING: Department of Ophthalmology, Queen's Medical Centre, Nottingham, United Kingdom. METHODS: This retrospective chart review comprised 82 consecutive eyes of 82 patients who had vitrectomy for retained lens material after phacoemulsification between January 2000 and June 2006. Data on demographics, preexisting eye conditions, cataract surgery details, findings at presentation, interval between phacoemulsification and vitrectomy, details of vitrectomy, details of follow-up visits, and postoperative complications were collected. RESULTS: The incidence of raised intraocular pressure (IOP) was 46.3%. Anterior vitrectomy was associated with a lower incidence of increased IOP (P = .006). There was no association between late vitrectomy and a worse visual outcome. There was a much lower rate of complications than in other studies; the incidence of retinal detachment and of cystoid macular edema was 4.9%, and there were no cases of endophthalmitis. CONCLUSION: The incidence of raised IOP in patients who had anterior vitrectomy at the time of cataract surgery was low. The visual outcomes were good, and the incidence of complications was low irrespective of the timing of the PPV.     

Management of dislocated lens fragments during phacoemulsification.

BACKGROUND: Dislocation of nuclear lens fragments during phacoemulsification can lead to a high incidence of glaucoma, uveitis, and poor visual acuity. The correct approach to these patients is uncertain. The authors report on eight patients who underwent pars plana vitrectomy with removal of lens fragments. METHODS: Charts of eight consecutive patients who developed dislocation of nuclear lens fragments into the vitreous cavity during phacoemulsification were retrospectively reviewed. All patients underwent a standard three-port pars plana vitrectomy with removal of the dislocated nuclear fragments by pars plana fragmentation. After the vitrectomy, the retina was inspected with indirect ophthalmoscopy. Tears were treated with cryopexy. A fluid-air exchange and scleral buckle were performed when indicated. RESULTS: Retinal tears were located at the vitreous base in four of eight patients. After vitrectomy, visual acuity improved in all patients, with 7 of 8 patients achieving visual acuity of 20/40 or better. The type of pseudophakia did not influence the final visual acuity. There were no cases of glaucoma, uveitis, or macular edema with up to 22 months of follow-up. CONCLUSIONS: These results suggest that large nuclear fragments dislocated into the posterior segment during phacoemulsification can be removed safely with pars plana vitrectomy and lensectomy with an excellent visual prognosis. Attempts to remove lens fragments during the phacoemulsification through an anterior wound should be avoided because of excessive vitreous traction, leading to retinal break formation.     

Retained intravitreal lens fragments after phacoemulsification: complications and visual outcome in vitrectomized and nonvitrectomized eyes

PURPOSE: To evaluate the ocular complications and visual outcomes in vitrectomized and nonvitrectomized eyes with retained lens fragments after phacoemulsification. SETTING: Department of Neurological, Psychiatric, and Ophthalmological Sciences, University of Padua, Padua, Italy. METHODS: This prospective nonrandomized study comprised 36 consecutive patients with retained intravitreal lens fragments after phacoemulsification. Eighteen eyes had a pars plana vitrectomy (Group 1), and 18 eyes (Group 2) were treated with medication only. Intraocular pressure (IOP), intraocular inflammation, cystoid macular edema (CME), and best corrected visual acuity (BCVA) were evaluated 1, 3, and 6 months postoperatively. RESULTS: Ophthalmoscopy and B-scan echography showed that the lens fragments were significantly larger in Group 1 than in Group 2 (P < .03). An uncontrollable IOP rise and inflammation prompted an early vitrectomy in 11 eyes in Group 1. At the 6-month follow-up, the IOP with medications was acceptable in 2 and 5 eyes in Group 1 and Group 2, respectively. Intraocular inflammation was no longer detectable 1 month after vitrectomy but persisted during the entire follow-up in Group 2. At 3 months, 5 eyes in Group 1 and 13 in Group 2 had CME and at 5 months, 3 eyes and 1 eye, respectively, had CME. The difference between groups was significant at both follow-ups (P < .05). Three retinal detachments, 1 before and 2 after vitrectomy, occurred in Group 1. The mean BCVA in Group 1 was better than in Group 2 during the entire follow-up; however, the difference was significant at 3 months only (P < .5). At 6 months, 94.4% in Group 1 and 83.2% in Group 2 had a BCVA of 20/50 or better and 66.6% and 55.5%, respectively, attained at least 20/30. CONCLUSIONS: Intraocular inflammation, increased IOP, and CME were major complications in nonvitrectomized eyes after phacoemulsification; retinal detachment occurred in 2 vitrectomized eyes. In eyes with intravitreal lens fragments after phacoemulsification, vitrectomy can yield faster visual rehabilitation and better quality of vision. Conservative management is feasible at the price of long-term intraocular inflammation and slower restoration of comparable visual function.