保留十二指肠的胰头切除1例

患者 ,女 ,5 5岁 ,曾因腹痛腹胀于 2个月前在某基层医院行胆囊切除及胆总管探查取石术 ,术中发现胰头部有肿块 ,约 2ｃｍ× 3ｃｍ大小 ,性质难定 ,当时未作处理 ;术后腹痛腹胀症状无明显改善 ,且患者自诉上述症状呈进行性加重 ,遂来本院就诊而入院。ＭＲＩ示胰头占位肿块 ,2ｃｍ× 3ｃｍ大 ,提示有胰头癌的可能。Ｂ超示胰头肿块 ,性质待定。肝功能检查 :总胆红素、直接胆红素以及ＧＯＴ、ＧＰＴ、γ ＧＴ和ＡＫＰ等均在正常范围内。血清肿瘤标志物ＣＡ19 9和ＣＥＡ等均无异常。体检 :皮肤巩膜无黄染 ,心肺无殊 ,全腹平软 ,腹部未扪及包块 ,…     

保留十二指肠胰头切除联合胆总管切除治疗胰管结石

胰管结石伴慢性胰腺炎通常采用胰管切开取石、胰管空肠吻合术 ,但远期效果不佳 ,逆行反复慢性感染和合并癌变发生率高。我们用保留十二指肠胰头切除 (ＤＰＲＥＰ)联合胆总管切除术治疗一例 ,取得较好疗效。报告如下。1　病例资料　　患者 ,男 ,32岁 ,因上腹部疼痛于 1998年 12月 30日住院。既往多次Ｂ超、ＣＴ检查示为慢性胰腺炎、胰管结石、胆总管扩张。查体 :皮肤、巩膜轻度黄染、无肝掌和蜘蛛痣。腹软 ,上腹部压痛 ,未扪及包块 ,肋缘下未扪及肝脾。实验室检查 :血淀粉酶 2 80苏氏单位。ＣＴ报告 :慢性胰腺炎 ,胰管结石并钙化。彩色Ｂ超 :…     

保留十二指肠胰头切除联合Oddi's括约肌成形治疗胰管结石

保留十二指肠的胰头切除(DPRHP)主要用于治疗胰腺头部良性疾病.我院于1997年10月为1例胰头部多发性结石伴胆总管远端梗阻患者施行DPRHP联合Oddi's括约肌成形术,取得较好疗效.报告如下.     

保留十二指肠胰头切除联合Oddi‘s约肌成形治疗胰管结石

保留十二指肠的胰头切除(DPRHP)主要用于治疗胰腺头部良性疾病.我院于1997年10月为1例胰头部多发性结石伴胆总管远端梗阻患者施行DPRHP联合Oddi's括约肌成形术,取得较好疗效.报告如下.     

保留十二指肠胰头勺式切除术治疗慢性胰腺炎合并胰管结石的前瞻性研究

目的探讨保留十二指肠的胰头勺式切除术治疗慢性胰腺炎合并Ⅰ、Ⅲ型胰管结石患者的疗效。方法前瞻性分析2008年6月至2013年6月湖南省人民医院收治的55例慢性胰腺炎合并Ⅰ、Ⅲ型胰管结石患者的临床资料,按随机数字表法将患者分为经典组27例（行胰十二指肠切除术）和勺式组28例（行保留十二指肠的胰头勺式切除术）。经典组患者中慢性胰腺炎合并Ⅰ型胰管结石18例,合并Ⅲ型胰管结石9例。勺式组患者中慢性胰腺炎合并Ⅰ型胰管结石16例,合并Ⅲ型胰管结石12例。经典组患者行传统胰十二指肠切除术,消化道重建采用Child吻合,胰肠吻合采用胰腺空肠端侧套入式吻合,放置胰管支撑管。胆肠吻合采用空肠与胆总管端侧连续吻合。勺式组患者行保留十二指肠的胰头勺式切除术,作Kocher切口,游离十二指肠,采用“四边法”向胰头方向切开胰管。距离十二指肠边缘1cm处切除胰管前方的胰腺组织,暴露胰头部的各分支胰管,取尽结石,沟通主胰管。对合并Ⅲ型胰管结石的患者,必要时可剖开胰体尾部的胰管取石。消化道重建采用胰勺面空肠Roux—en—Y吻合术。采用门诊随访,随访时间截至2013年12月。计量资料采用t检验和Mann—WhitneyU秩和检验,计数资料采用矿检验。结果术中经典组2例患者改行保留十二指肠的胰头勺式切除术,勺式组1例患者改行胰十二指肠切除术。经典组实际施行手术人数为26例,勺式组为29例。所有患者围手术期无死亡,腹痛、腹泻等消化道症状多在术后2周左右得以改善。经典组患者手术时间为（7．5±1．6）h,出血量为（460±88）mL,术后住院时问为（18．0±3．5）d,住院费用为（7．8±2．1）万元,并发症发生率为19．2％（5／26）。勺式组患者手术时间为（4．0±1．0）h,出血量为（120±36）mL,术后住院时间为（9．5±2．9）d,住院费用为（3．9±1．2）万元,并发症发生率为3．4％（1／29）。两组患者在手术时间、出血量、术后住院时间、住院费用及并发症发生率等方面比较,差异均有统计学意义（t=9．358,11．365,6．325,8．647,x2=3．976,P〈0．05）。53例患者获得随访,中位随访时间为33个月（6个月至5年）,随访期间无患者死亡。经典组患者中24例获得随访,其中2例患者术后仍有轻微腹痛,1例腹痛剧烈,诊断为胰肠吻合口处胰管开口狭窄,经再次手术切除部分胰体组织后缓解;19例合并糖尿病的患者中12例病情好转或血糖恢复正常。勺式组患者均获得随访,其中2例术后轻微腹痛,疼痛时间较为短暂,未行处理;22例合并糖尿病的患者中16例血糖恢复正常。结论对慢性胰腺炎并Ⅰ、Ⅲ型胰管结石的患者,保留十二指肠的胰头勺式切除术是较为理想的术式。     

慢性胰腺炎伴胰管结石的诊断与外科治疗

目的：探讨慢性胰腺炎伴胰管结石的诊断特点与手术方法的选择。方法：回顾分析外科治疗的慢性胰腺炎伴胰管结石的16例临床资料。结果：16例中常见的临床症状是腹痛(占100％)、食欲不振及恶心呕吐(占62．5％)、脂肪泻(占12．5％)、消瘦(占18．8％)及腹部肿块(占6．3％)。胰管扩张及胰腺结石的B超诊断率分别为81．3％及75．0％；胰管结石的腹部平片诊断率为81．3％；胰管结石的CT和MRI诊断率均为61．5％，包括胰头部局限性肿大为23．1％和胆总管扩张15．4％。手术方式包括胰管切开减压胰管空肠内引流术10例(Partington手术9例及Puestow手术1例)，胰十二指肠切除术3例(Child方法)，胰体尾部切除术3例(联合胆总管切开、T管引流术2例)。结论：严格选择适应证和合理的手术方式，对改善慢性胰腺炎伴胰管结石患者的生活质量和控制疾病发展具有重要作用。     

胰头切除胰管引流术治疗胰管无扩张的慢性胰腺炎

慢性胰腺炎出现并发症或顽固性腹痛的患者常需要手术干预，胰管空肠吻合术通过解除胰管阻塞、引流胰液，从而达到缓解疼痛和部分恢复胰腺功能的目的。然而以前认为这种引流术只适用于胰管扩张的患者，对于胰管无扩张或狭窄的慢性胰腺炎患者，引流效果欠佳，常用的术式为胰腺部分或全部切除术，但造成胰腺功能的下降或缺失，降低了病人     

胰十二指肠切除术中胰管空肠吻合的经验

胰十二指肠切除术是胰头癌、总胆管下段癌、壶腹部及部分十二指肠恶性肿瘤首选的手术方法。近年来手术死亡率明显减少，但术后并发症仍然未见明显减少。本总结本院近15年来43例胰十二指肠手术的经验，并予报告。     

胰管栓塞预防胰十二指肠切除术后胰瘘的作用分析

目的 探讨胰十二指肠切除术(PD)采取胰管栓塞的方法,以达到预防胰瘘的目的。方法 PD术中从胰管断端插管注入“TH”粘胶栓塞胰管,消化道重建按Child术式进行。结果 在PD术中共行胰管栓塞12例,均未发生胰瘘。结论 胰管栓塞可有效地预防PD术后胰瘘,尤适用于基层医院。     

合并主胰管断裂的胰腺外伤诊断与治疗分析

目的 对胰腺外伤合并主胰管损伤的诊治进行探讨.方法 回顾性分析44例严重胰腺外伤同时合并主胰管断裂患者的临床资料及诊治经过.结果 B超联合CT检查对外伤性严重的胰腺损伤确诊率为100%,但是否合并主胰管损伤则需要手术中探查结果来实现.本组患者行远端胰腺空肠Roux-Y吻合术27例,改良十二指肠憩室化和十二指肠空肠Roux-Y吻合术3例,胰十二指肠切除2例.41例患者经救治均痊愈出院.并发症发生率为29.5%,病死率为6.8%.结论 胰腺损伤临床表现隐蔽,CT可提高术前确诊率.而降低严重胰腺外伤患者的病死率关键在于提高术前诊断率、及时和选择合理的手术方式以及加强手术并发症的预防与治疗措施.     

Cystic duct directly joining the main pancreatic duct

A unique anomaly of the direct union between the cystic duct and the main pancreatic duct is presented. A 19-year-old man with a history of repeated epigastralgia underwent endoscopic retrograde cholangiopancreaticography that showed a direct union between the cystic duct and the main pancreatic duct. No pancreaticobiliary maljunction was noticed. Cholecystectomy accompanied by resection of the long cystic duct was performed. The excised gallbladder showed cholesterolosis, chronic cholecystitis, and hyperplasia of the pseudopyloric glands microscopically. The patient has been well for 3 years since surgery.     

胰管结石的外科治疗(附116例报告)

目的 总结胰管结石的外科治疗方式.方法 回顾性分析2007年1月至2012年12月间外科手术治疗胰管结石116例的临床资料.结果 胰十二指肠切除术者45例,胰管切开取石并行胰管空肠侧侧吻合者33例,Beger手术17例,Frey手术12例,胰体尾切除术9例.9例已发生胰腺癌变.全组无围手术期死亡,术后发生并发症12例,发生率为 10.3%.术后3个月,绝大多数患者症状有明显改善.105例术后全程随访发现:92例胰管结石患者存活至今,一般情况良好,6例胰腺癌患者因肿瘤复发病故,1例胰管结石患者因糖尿病及严重营养不良病故,6例因其他原因病故.结论 手术治疗是胰管结石达到根治性治疗的理想方法,按照胰管结石的治疗原则,依据结石及胰腺病变的具体情况选择合理的手术方式,是取得良好疗效的关键.     

胰管结石外科治疗术式探讨

目的探讨胰管结石外科治疗的术式选择。方法对7例胰管结石患者进行手术治疗。采用胆管、胰管空肠(侧侧)Roux-Y吻合术 胆囊切除、胆管探查、T管引流术4例,采用胰管切开取石、胰管空肠(侧侧)Roux-Y吻合术 胆管探查、T管引流术1例,采用保留十二指肠的胰头切除、尾侧胰腺断端空肠(端侧)Roux-Y吻合术 胆囊切除及胆总管探查取石、T管引流术1例,采用胰十二指肠切除术1例。结果7例均痊愈,其中1例术前并发上消化道大出血,误切第一组小肠,遗有短肠综合征;另1例生存至1.5年后发生胰腺癌变死亡。结论外科手术仍是本病主要的治疗方法,主要有引流术和胰腺部分切除术,有主胰管扩张者宜采用引流术,无胰管扩张和胰腺病变局限化者,可用胰腺部分切除术,再联合内引流术;依据胰腺病变的具体情况选择最佳术式,手术疗效满意。     

Obstructive jaundice associated with pancreatic duct stone

Pancreatic stone is a rare disease, and it may be associated with obstructive jaundice. We recorded clinical data and accurate images of the pancreatic stone. Whipple operation was performed to relieve the obstructive jaundice. The pancreatic stone is an uncommon entity with obstructive jaundice and may require surgical management if endoscopy or extracorporeal shock wave lithotripsy failed.     

Intraductal papillary-mucinous tumor of the pancreas head with complete absence of the ventral pancreatic duct of Wirsung

A case of intraductal papillary mucinous tumor of the pancreas with complete absence of the ventral pancreatic duct of Wirsung is presented. A 74-year-old Japanese man was admitted to our hospital because of elevated serum amylase concentration. Abdominal computed tomography (CT) scanning revealed diffuse dilatation of the main pancreatic duct and a diffuse and uncircumscribed area with heterogeneous density in the pancreas head. Endoscopic retrograde cholangiopancreatography revealed that the main pancreatic duct was connected with an accessory papilla and was diffusely dilated, without any irregularity of the duct wall being observed in the entire length of the duct. The common bile duct was detected only by cannulation through Vaters papilla, and no pancreatic duct or its communicating branch was found. Some branches, directed to the dorsal portion of the pancreas head, were found arising from the accessory pancreatic duct. Intraductal ultrasound examination performed through the accessory papilla and the common bile duct revealed a small tumor with a heterogeneous echo level in the pancreas head. From these findings, intraductal papillary-mucinous tumor (IPMT) occurring in the pancreas head was diagnosed, and pylorus-preserving pancreaticoduodenectomy was performed. The resected specimen revealed IPMT in the pancreas head. A roentgenographic study of the resected specimen revealed a defect caused by the tumor located in the pancreatic duct connected with the accessory papilla and showed that there was complete absence of the pancreatic duct connected with Vaters papilla. Surgical resection enabled us to completely analyze the duct system of pancreas divisum. Although it is not known whether there is a relationship between the pathogenesis of IPMT and embryological anomaly of the pancreatic duct system, this case may provide an insight into the pathogenesis of IPMT.