Accessory limbs with spinal lesions

Congenital accessory limbs are exceedingly rare anomalies, only two having been reported previously. We present three additional cases, two of these with associated spinal lesions a phenomenon reported only once in the past.     

Juvenile xanthogranuloma with extracutaneous lesions

The purpose of this article is to present a case of juvenile xanthogranuloma with pulmonary, retroperitoneal and splenic involvement. The similar echographic pattern of the cutaneous and visceral lesions was very helpful in order to suggest the correct diagnosis.     

儿童传染性单核细胞增多症的肝脏损害特点

<正> 传染性单核细胞增多症(IM)是一种单核巨噬细胞系统的急性或亚急性增生性疾病,临床上除引起常见的发热、咽峡炎、淋巴结肿大外,还可损害其他重要脏器,尤其是对肝脏损害,现将我院收治的IM患儿肝脏损害情况报告如下。     

A boy born with multiple lesions of atrophoderma

Aims: The Atrophodermas include a large group of disorders appearing as localized or widespread depressed skin areas and characterized by underlying dermal atrophy. The present study aims to report a peculiar form of previously unreported focal dermal atrophy. Methods: We studied over a period of 5 years a boy who manifested, since birth, multiple hypopigmented cutaneous atrophic lesions of the atrophoderma type in a mosaic distribution over the body and the legs. Results: This boy did no develop other cutaneous or systemic stigmata except for an idiopathic thrombocytopenic purpura (ITP) manifested at age 2 years. Full serum, metabolic and infective analyses; full ophthalmological examination; ultrasound examination of the heart and internal organs; skeletal x‐rays; brain magnetic resonance imaging; and DNA analysis of the PORCN (Focal Dermal Hypoplasia ‐ FDH) gene in this boy yielded normal results. Pathological analysis of multiple skin specimens from an affected area revealed slightly reduced dermal thickness; hyperpigmentation of the basal layer; homogenized and disarrayed collagen bundles; perivascular chronic infiltrates of lymphocytes and histiocytes; and normal skin appendages. Currently, the child is healthy; he has mildly improved skin status with less‐evident skin depression throughout the lesion areas and no further complication has been recorded. The histological and clinical appearance of the skin lesions and the course were against any known disorder in the group of the atrophodermas. Conclusions: The cutaneous lesions seen in this boy represent a possibly new congenital skin disorder characterized by multiple, benign areas of focal dermal atrophy in a mosaic distribution.     

Characterization of pediatric liver lesions with gadoxetate disodium

Gadoxetate disodium (Gd-EOB-DTPA) is a relatively new hepatobiliary MRI contrast agent. It is increasingly used in adults to characterize hepatic masses, but there is little published describing its use in children. The purpose of this paper is to describe our pediatric MRI protocol as well as the imaging appearance of pediatric liver lesions using gadoxetate disodium. As a hepatocyte-specific MRI contrast agent, Gd-EOB-DTPA has the potential to improve characterization and provide a more specific diagnosis of pediatric liver masses.