准分子激光原位角膜磨镶术前后蓝／黄视野分析

目的研究准分子激光原位角膜磨镶术（laser in situ keratomileusis,LASIK）对患者视野的影响。方法用Octopus101全自动视野计G2程序的TOP／BY分程序对LASIK手术的近视患者于术前、术后6个月行视野检查。结果术后视野的平均敏感度（meansen sitivity。MS）与术前比较，差异无显著性（P〉0．05）。术后视野的指数平均缺损（mean defect，MD）与术前比较。差异有显著性（P〈0．01）。手术前、手术后视力与手术前后各自视野MS、MD均无显著相关性（P〉0．05）。手术前后MS和MD平均差值与术前屈光度数、角膜切削百分比、激光切削时间、负压吸引时间、瞳孔直径、年龄、性别等行Spearman相关分析显示均无相关性（P〉0．05）。结论手术对视网膜和视神经结构和功能影响还不足以导致临床上明显的功能损伤，没有表现出有临床意义的功能改变。LASIK手术前后视野无明显变化。蓝，黄视野计与标准白色视野计检测的视野结果一致，说明两者检测敏感性相当。     

准分子激光原位角膜磨镶术后视野改变分析

目的探讨近视眼患者进行准分子激光原位角膜磨镶术（LASIK）治疗后的视野变化。方法采用DICONTKS-4000型计算机自动视野分析仪TRS检测程序对40例（80只眼）近视眼患者于术前、术后1、3、6个月进行视野检查,比较视野改变。结果术后视野平均光敏感度（MS）与术前比较,差异有统计学意义（P〈0.05）,术后视野平均缺损（MD）与术前比较,差异有统计学意义（P〈0.05）,手术前后视力与各自视野MS、MD无显著相关性（P〉0.05）,手术前后MS和MD平均差值与术前屈光度数、切削百分比、激光切削时间、负压吸引时间等行等级相关分析均显示无明显相关性（P〉0.05）。结论LASIK后视野敏感度下降主要是由于屈光性因素影响,虽然有导致玻璃体、视网膜和视神经损伤的病理基础,但还不足以导致临床上显著的形态和视功能上的改变,对视网膜组织正常生理功能没有明显影响。     

准分子激光术后近视回退和欠矫原因分析

目的：探讨准分子激光近视治疗术后屈光回退和欠矫的原因,为临床提供理论依据。方法：将我院近视中心准分子激光术后发生屈光回退并行二次手术的45例70眼,按〈-6．00D为Ⅰ组,〉-6．00D度为Ⅱ组,将两组患者两次治疗前后屈光度、术后不同时间的视力、术式、切削光斑直径、角膜切削量及残留厚度等相关资料进行了对比分析。结果：两组未手术时屈光度差别显著（P〈0．05）。屈光回退后两组屈光度差别无意义（P〉0．05）。Ⅰ,Ⅱ两组首次激光术后6mo内,不同时间点裸眼视力与术前矫正视力有明显差别（P〈0．05）。二次手术后,1wk内裸眼视力与矫正视力差别明显（P〈0．05）,1～3mo无差别（P〉0．05）;Ⅰ组于6mo时裸眼视力与矫正视力出现差别（P〈0．05）,Ⅱ组差别不显著（P〉0．05）;两组激光切削光斑的直径及角膜切削量有明显差别（P〈0．05）。结论：准分子激光近视治疗术后,屈光度回退程度与术前屈光状态无关。不同屈光度屈光回退程度相同。高度近视、LASIK多区切削和切削光斑直径小是发生屈光回退和欠矫的主要原因。     

准分子激光原位角膜磨镶术与准分子激光角膜上皮瓣下磨镶术后角膜知觉恢复的研究

目的 比较准分子激光原位角膜磨镶术（LASIK）和准分子激光角膜上皮瓣下磨镶术（LASEK）后角膜知觉的恢复情况。方法 本研究观察在我院行LASIK或LASEK近视矫正的患者59例（59只眼）,包括低、中度近视行LASEK者20只眼,高度近视行LASEK者30只眼,以及低、中度近视行LASIK者9只眼。分别在术前、术后2周、1、3、6个月时测量角膜中央知觉,并和切削深度进行相关性检验。结果 LASIK和LASEK术后角膜知觉均下降,但LASIK术后下降更明显。在各观察时间点,LASEK术后的角膜知觉均好于LASIK术后2周、1个月和3个月时差异均有统计学意义（P〈0．01）,6个月时P=0．031。低、中度近视LASIK术后6个月时角膜知觉仍未恢复（P=0．023）;而LASEK术后3个月时角膜知觉已恢复（P〉0．05）。高度近视LASEK术后6个月时角膜知觉基本恢复（P〉0．05）。LASEK术后1、3及6个月的角膜知觉和切削深度有相关性（r=0．419,0．433,0．413;P〈0．05）,其余观察时间点两者无相关性。LASIK术后各时间点的角膜知觉和切削深度无相关性（P〉0．05）。结论 LASEK术后角膜知觉的恢复较LASIK术后快,LASEK术后角膜知觉的恢复和切削深度有关。     

高度近视眼行准分子激光非球面切削的临床观察

目的观察高度近视眼行准分子激光非球面切削与普通球面切削的视力、Q值和像差差异，探讨非球面切削对提高视觉质量的作用。方法高度近视眼病例56例（112眼）分为两组，分别行非球面切削（52眼）与普通球面切削（60眼），对两组术后10d，1、3、6个月的视力、Q值以及术后6个月的像差变化进行分析。结果两组术后各时期裸眼视力均可达到术前最佳矫正视力（P〉0．05），普通球面切削组术后各时期Q值均较术前显著增加（P〈0．01），非球面切削组术后10d、1个月Q值较术前显著增加（P〈0．01），3个月、6个月Q值较术前增加（P〈0．05），两组各时期Q值差异有统计学意义（P〈0．05），术后6个月两组的球差均较术前增加，而球面切削组像差增加又明显高于非球面切削组（P〈0．05）。结论使用非球面切削在一定程度上可以解决准分子激光原位角膜磨镶术（LASIK）术后高阶像差增加的问题，对提高术后视觉质量有一定意义。     

LASIK术后角膜知觉的变化及干眼的发生

目的：探讨准分子激光原位角膜磨镶术（LASIK）后角膜知觉的变化及其对干眼的影响与切削深度的关系。 方法：观察上方蒂做瓣的LASIK手术30例（60眼），观察指标包括患者术中切削深度及术前，术后1wk，lmo，3mo的角膜中央知觉、基础泪液分泌量、泪膜破裂时间（BUT）、角膜荧光素钠染色评分、干眼主觉症状评分。 结果：术后1wk，1mo角膜知觉敏感度与术前相比差异均非常显著（P〈0．01），术后3mo平与术前相比差异无统计学意义（P〉0．05）；术后1wk患者的主觉症状与术前相比无显著差异（P=0．079〉0．05），术后mo时差异显著（P=0．025〈0．05），术后3mo时差异极其显著（P=0．001〈0．01）；患者术后泪流量在术后1wk：1mo时明显低于术前（P〈0．01），直至术后3mo仍未恢复至术前水平（P〈0．01）；术后1wk，1mo，3mo泪膜破裂时间缩短，术后3mo时与术前相比差异显著（P〈0．01）；角膜荧光素钠染色评分方面，术后1mo时角膜上皮损伤最明显，术后3㈤时与术前仍有显著差异（P〈0．01）直线回归与相关分析结果，说明在两者之间存在直线相关的关系r=0．798，P〈0．01。 结论：LASIK术后角膜中央知觉明显下降并随时间延续而逐渐恢复，3mo时与术前无统计学差异；但是干眼的相关指标并未随之恢复至术前水平；术后角膜知觉的下降与术中切削深度间存在正相关。     

高度近视LASIK与LASEK术后角膜后表面高度临床研究

目的探讨高度近视准分子激光原位角膜磨镶术（LASIK）及准分子激光上皮瓣下角膜磨镶术（LASEK）术后角膜后表面高度的差异及意义。方法随机选取高度近视准分子激光患者32人59眼，其中LASIK术31眼17人、LASEK术28眼15人，近视等效球镜度数均〉-6．0D。术前、术后1d、术后2w、术后1m、术后3m、术后6m应用Orbscan Ⅱ行角膜地形图检查。分析比较LASIK及LASEK两组间各个不同时间点的角膜后表面高度。结果LASIK组与LASEK组角膜后表面顶点高度术后与术前比较，差异均有显著统计学意义（P均〈0．05）。LASIK组角膜后表面前隆高度术后1m、术后3m、术后6m较术后1d、术后2w好转，差异有显著统计学意义（P均〈0．05）。LASIK与LASEK两组间角膜后表面前隆高度比较：术后2w时LASIK组较LASEK组角膜后表面前隆高度更大，差异有显著统计学意义（P均〈0．05），术后1m起两组间差异无统计学意义（P〉0．05）。结论高度近视LASIK及LASEK术后角膜后表面均有前隆，早期以LASIK术更为明显。     

全飞秒激光角膜基质透镜切除术与飞秒激光制瓣的LASIK术后角膜地形图比较

目的对全飞秒激光角膜基质透镜切除术（Flex）与飞秒激光制瓣的LASIK（FS—LASIK）术后3个月近视散光患者的角膜形态进行比较研究。方法前瞻性病例对照研究。对2013年1-9月在北京同仁医院的近视散光患者165例（323眼）进行Flex（87例170眼）或FS—LASIK（78例153眼）手术,术后3个月时,对2组视力、屈光状态及角膜形态参数进行独立样本t检验。结果Flex组和FS—LASIK组术后3个月时,logMARUCVA分别为-0．10±0．08和-0．11±0．10,矫正视力分别为-0．11±0．07和-0．12±0．07,均较术前BCVA（-0．07±0．03和-0．07±0．04）提高（t=4．083、5．594、3．458、6．440,P〈0．01）,2种手术方式之间差异均无统计学意义（t=-0．811、-1．864,P〉O．05）。Flex和FS—LASIK切削偏心量分别为（0．29±0．17）mm和（0．40±0．17）mm,二者差异有统计学意义（t=5．662,P〈0．01）。Flex切削偏心程度与术前等效球镜度不相关（r=0．122,P〉0．05）：FS—LASIK切削偏心程度与术前等效球镜度呈正相关（r=0．210,P〈0．01）。Flex和FS—LASIK术后角膜表面规则指数（SRI）分别为0．34±0．25和0．22±0．21,二者比较差异有统计学意义（t=-4．627,P〈0．01）。结论Flex术后切削偏心程度比FS-LASIK小,FS-LASIK术后角膜表面规则性比Flex更好,二者术后都可获得满意的视力。     

高度近视LASIK与LASEK术后角膜地形图的变化

目的分析高度近视LASIK与LASEK术后角膜地形图的变化,评价LASEK治疗高度近视的效果。方法选取接受准分子激光高度近视矫正术的连续性病例68例（125眼）。术前等效球镜值为-6．00D～-12．00D,平均（-8．91±2．12）D。按手术方式分为两组：LASEK组和LASIK组。比较术前、术后1个月、3个月和6个月患者角膜地形图的变化。结果两组术前角膜地形冈均以不对称领结型为主,LASEK组为55．6％,LASIK组为54．7％,两组差异无统计学意义（P〉0．05）;术后6月,两组均以平滑型为主,LASEK组为79．2％,LASIK组为83．0％,两组均无偏中心切削或中央岛型,两组差异无统计学意义（P〉0．05）。随着时间的推移,两组中的半环型均向平滑型转变。术后1个月、3个月、6个月与术前相比,两组模拟角膜镜度数（simk）的等效值、Simk差值明显减小,角膜不规则指数（CIM）明显增高,角膜形态因子（SF）向负值改变,其差异有统计学意义（P〈0．05）。术后1个月,LASEK组CIM值、Simk差值、SF绝对值均高于LASIK组,两组差异有统计学意义（P〈0．05）。术后3个月和6个月LASEK组CIM值低于LASIK组,两组差异有统计学意义（P〈0．05）,而Simk差值、Simk等效值及SF绝对值与LASIK组相比,差异无统计学意义（P〉0．05）。结论LASEK治疗高度、超高度近视术后角膜地形网形态较LASIK平整、规则。远期效果有待进一步观察。     

近视眼准分子激光原位角膜磨镶术后角膜非球面性的改变

目的 研究近视眼准分子激光原位磨镶术（laser in situ keratomileusis，LASIK）后角膜非球面性的改变。方法 对93例近视眼患者（148眼）LASIK术后进行回顾性分析．用Orbscan-Ⅱ角膜地形图仪测量角膜在LASIK术前和术后非球面参数Q值、角膜曲率simk值（K）、切削的偏心值。分析Q值、角膜曲率改变（△K），△Q与预期矫正值（SE）、AK之间的相关性，以及术后。值与偏心量之间的相关性。结果 角膜形状从术前扁长型（Q〈0）到术后为扁圆型（Q〉0）；角膜曲率变平；AQ与SE、AK之间存在相关性（分别为r=0．771，P〈0．01和r=0．783，P〈0．01），但术后Q值与偏心量之间无相关性（r=0．068，P〉0．05）。结论 近视患者LASIK术后角膜非球面参数Q明显增大，变化量与预期矫正值、曲率变化量相关。     

准分子激光原位角膜磨镶术后视野改变

目的:探讨准分子激光原位角膜磨镶术(laser in situ keratom ileusis,LASIK)对近视及近视散光患者30°中心视野的影响。方法:将实施LASIK的近视患者45例89眼分为两组:中低度近视组和高度近视组。Ⅰ组:中低度近视组60眼,近视-1.50～-6.00D;Ⅱ组:高度近视组29眼,近视-6.00～10.00D。用Humphrey视野计30-2SITA快速阈值检测程序对所有患者的术前、术后1wk;1,3,6mo的视野进行检查,观察其视野改变情况。观察指标为平均缺损(mean defect,MD)和模式标准差(pattern standard deviation,PSD)。统计学分析采用重复测量的方差分析和非参数分析的秩和检验,分析各时间点视野指数。结果:中低度近视组:术后1wk;1,3mo的MD与术前相比,差异有统计学意义(P<0.05),术后6mo时MD值与术前相比差异无统计学意义;PSD值术后各时间点与术前相比差异无统计学意义。高度近视组:术后1wk;1,3mo时的MD均较术前增加,并且随时间变化的差异有统计学意义(P<0.05);其中,1wk时MD值上升最明显,以后逐渐下降,但仍高于术前水平;术后6mo时恢复至术前水平(P>0.05);术后1wk时的PSD与术前相比差异有统计学意义(P<0.05),其余各时间点PSD值与术前相比差异无统计学意义。结论:LASIK手术对高度近视眼患者1wk的视野有影响,对中低度近视患者的视野改变无影响。     

Characteristics of sixty myopic eyes with pre-laser in situ keratomileusis retinal examination and post-laser in situ keratomileusis retinal lesions

PURPOSE: A survey of eyes with pre-laser in situ keratomileusis (LASIK) retinal examinations and characteristics of post-LASIK retinal breaks and retinal detachments (RDs). METHODS: A survey of worldwide vitreoretinal surgeons (424 physicians). Surveyed information included demographics, best-corrected visual acuity, degree of myopia, pre- and post-LASIK retinal findings, follow-up time, and treatment outcome. RESULTS: Sixty eyes with pre-LASIK retinal examinations developed post-LASIK retinal breaks and RDs. There was an average of 2.3 breaks per eye, yielding a total of 140 breaks in the 60 eyes. Forty eyes also had RDs besides the retinal breaks. Large percentages of eyes had substantial myopia (mean myopia, -9.5 +/- 5.8 diopters [D]) and complex vitreoretinal complications. Forty percent developed vitreoretinal complications within 6 months after LASIK. The 20 eyes that developed more extensive RDs (>3 clock hours) had a significantly higher mean myopia than did the 6 eyes that developed limited RD (< or = 3 clock hours) within 12 months after LASIK (-8.92 +/- 6.82 D versus -3.50 +/- 1.97 D, P = 0.03). There were significant statistical differences in distribution of retinal breaks and tears between the temporal and nasal quadrants (P < 0.001, P < 0.001, respectively, chi2, but not between the superior and inferior quadrants. CONCLUSION: Distributions of retinal breaks in this study were comparable with results found in non-LASIK eyes in young myopes. Treatment for post-LASIK vitreoretinal complications was highly successful. The vulnerability of such highly myopic eyes for vitreoretinal complications warrants their close monitoring.     

近视性屈光不正LASIK手术前后对比敏感度的临床研究

目的:通过计算机对比敏感度检查仪对近视性屈光不正行准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)手术前后的空间对比敏感度进行检查,以探讨LASIK手术前后对比敏感度的变化情况。方法:对51例(101眼)LASIK手术患者术前进行常规的准分子激光术前检查、最好矫正视力和空间对比敏感度检查,并按近视的度数分为高度近视组和中低度近视组。LASIK手术后第1d,在裂隙灯显微镜下判断有无角膜微纹,并依据其进行进一步分组。分别检查术后0.5,1和3mo的最好矫正视力和空间对比敏感度。结果:LASIK术后0.5mo,虽然有99%的病例术后矫正视力达到5.0以上,但对比敏感度在各个空间频率上都有统计学意义上明显的下降(P<0.05)。术后1mo,中低度近视组对比敏感度在各个空间频率上有明显恢复,可达到术前水平。高度近视组术后1mo在中低空间频率上可恢复至术前水平,但在高频上(8,16cpd)较术前仍有统计学意义上明显下降,直至术后3mo仍不能恢复至术前水平(P<0.05)。有角膜微纹组对比敏感度下降较为明显,直至术后3mo,除了低空间频率的1cpd外,其他各个空间频率上均有统计学意义(P<0.05)的减退。结论:对比敏感度和传统的视力检查相比,能反映出检查眼在不同对比度下的视功能情况,更加接近日常生活中视觉需求。LASIK术后对比敏感度会出现暂时下降,并随着时间的推移逐渐恢复。高度近视和角膜微纹的病例术后对比敏感度恢复较慢。     

Visual field changes after laser in situ keratomileusis in myopic eyes

PURPOSE: To evaluate the effect of acute elevation of intraocular pressure (IOP) during laser in situ keratomileusis (LASIK) on the visual field in myopic eyes. SETTING: Istanbul University, Cerrahpassa Medical Faculty, Istanbul, Turkey. METHODS: Thirty-seven eyes of 37 patients were included in the study. The LASIK procedure was performed using the Hansatome microkeratome (Bausch & Lomb) and the Summit SVS Apex Plus 193 nm argon-fluoride excimer laser. Visual field testing was performed twice before LASIK and 1 day and 24 months after LASIK. Seventy-six points, 6 degrees apart, in the central visual field (Central 30-2) were tested for threshold sensitivity (Humphrey). The mean threshold sensitivity of baseline and post-LASIK visual field examinations was calculated in each patient. Seventy-six points of the Central 30-2 test were divided into 21 clusters corresponding to perimetric nerve-fiber bundles derived from Peridata software version 6.2a (Interzaag AG). The mean threshold sensitivity of each cluster and the visual field indices (mean deviation [MD] and corrected pattern standard deviation [CPSD]) in baseline and follow-up visual fields were compared using analysis of variance. RESULTS: The mean age of the 23 men and 14 women was 31.04 years +/- 6.55 (SD). The mean spherical equivalent refraction was -4.21 +/- 1.66 diopters (D) (range -2.25 to -6.75 D). The mean duration of suction was 42.29 +/- 29.06 seconds. The mean visual field sensitivity at baseline and the 2 follow-up examinations was 25.97 +/- 2.04 dB, 25.70 +/- 1.99 dB, and 27.17 +/- 1.68 dB, respectively (P =.181). There was no difference between preoperative and postoperative visual field clusters except in area 13. In area 13, threshold sensitivity was decreased at 1 day (P =.039) and at the preoperative level at 24 months. The MD of the visual fields was -3.53 +/- 1.67 dB, -3.61 +/- 2.91 dB, and -2.61 +/- 1.66 dB at the preoperative and 2 postoperative examinations, respectively (P =.495). The mean CPSD of the visual fields was 1.76 +/- 1.24 dB, 1.42 +/- 0.85 dB, and 1.74 +/- 0.86 dB, respectively (P =.680). CONCLUSION: Laser in situ keratomileusis did not cause visual field defects in mild to moderate myopic patients who had no risk factors that might render the optic nerve more vulnerable to damage.     

准分子激光原位角膜磨镶术后5年的疗效观察

目的 观察近视眼患者准分子激光原位角膜磨镶术（laser in keratomileusis, LASIK）后5年中央角膜厚度及角膜曲率等的变化情况,并分析LASIK的安全性和远期疗效.方法 接受LASIK手术的近视患者52例（104只眼）,检查患者术后5年的视力、屈光状态、中央角膜厚度及角膜曲率,并与术前及术后早期数据进行比较.结果 术后5年均未发生继发性角膜扩张或医源性圆锥角膜;最佳矫正视力均无下降;平均等效球镜度数为（0.043±0.502）D,其中94眼为0～0.50 D,占90.38%.术后各阶段视力较稳定,等效球镜度数3个月时渐趋稳定.术后1年与术后5年中央角膜厚度差异无统计学意义（P〉0.05）,而各自与术后预计角膜厚度相比差异有统计学意义（P〈0.05）,均较术后预计角膜厚度厚;术后1～5年角膜曲率差异无统计学意义（P〉0.05）.结论 LASIK治疗近视具有良好的预测性和稳定的远期疗效.     

LASEK与LASIK治疗高度近视

目的:对比观察准分子激光上皮瓣下角膜磨削术(LASEK)与准分子激光原位角膜磨削术(LASIK)治疗高度近视的临床疗效。评估2种手术的安全性和有效性。方法:对行LASEK治疗的39例75只眼和同期行LASIK治疗的41例79只眼高度近视分别进行6个月以上的临床观察。结果:LASEK组术后1周至1个月达最佳矫正视力,术后3个月部分出现视力回退,术后6个月裸眼视力达术前矫正视力占95.83%,主要并发症有术后高眼压及Haze形成;LASIK组术后6个月裸眼视力达术前矫正视力占94.35%,主要并发症为屈光回退,角膜上皮内生或角膜瓣皱折等。结论:LASIK与LASEK均能安全、有效地矫正高度近视。     

Pupil size and night vision disturbances after LASIK for myopia

PURPOSE: To examine whether standardized, preoperative evaluation of pupil sizes can predict the risk of night vision visual disturbances after bilateral laser in situ keratomileusis (LASIK) for myopia. METHODS: A prospective study was carried out involving 46 patients who underwent bilateral LASIK for myopia. Pupil sizes were measured before surgery using an infrared pupillometer under standardized settings. Pre- and postoperative refraction and best spectacle-corrected visual acuity (BSCVA) were registered. At the 3-month follow-up visit, the patients completed a questionnaire regarding night vision pre- and postoperatively. RESULTS: The mean bilateral, spherical equivalent refraction (SE) was - 8.76 D (range 6.32 to - 12.0 D) preoperatively, and - 1.69 D (range 0 to - 4.38 D) postoperatively. The mean bilateral BSCVA was not changed by the operations. We found a significant correlation between large scotopic pupil sizes and the impression of worsened night vision (p < 0.01). A significant correlation between gender (males) and subjectively reduced night vision postoperatively was also found (p < 0.05). CONCLUSION: Large pupil size measured preoperatively is correlated with an increased frequency of subjectively experienced post-LASIK visual disturbances during scotopic conditions. We recommend preoperative evaluation of pupil size in all patients prior to LASIK surgery.     

Visual field changes after laser in situ keratomileusis

PURPOSE: To determine whether laser in situ keratomileusis (LASIK) affects the central 30-degree visual field. SETTING: University-based ophthalmology practice. METHODS: This nonrandomized clinical trial comprised 14 normal patients (27 eyes) scheduled to have LASIK for myopia or myopic astigmatism. Automated static perimetry was performed before and 6 months after surgery using the Octopus 1-2-3 perimeter and the Dynamic-32 test strategy. Patient data included sex, age, preoperative and postoperative refractive errors, preoperative and postoperative best corrected visual acuity, preoperative corneal thickness, programmed optical zone, programmed total ablation diameter, and duration of microkeratome suction. All surgery was performed using the same Alcon LADARVision 4000 excimer laser. The main outcome measures were the mean sensitivity (MS) change in the central 15-degree visual field and the MS change in the 15- to 30-degree visual field. A multivariate analysis of the MS change as a function of preoperative clinical parameters was performed. RESULTS: There was no significant change in the MS in the central 15-degree visual field; between 15 and 30 degrees, there was a statistically significant decrease of -0.82 dB +/- 1.40 (SD) (P=.01, 2-tailed t test). The decline in MS was positively correlated with refractive error and corneal thickness; it was negatively correlated with the programmed optical zone diameter. CONCLUSIONS: Automatic static perimetry can detect decreased sensitivity in the midperipheral visual field after myopic LASIK. It may be a useful quantitative subjective test for measuring the effects of future improvements in surgical technique on vision quality.     

超高度近视准分子激光原位角膜磨镶术术后视力及屈光状态的改变

目的:探讨超高度近视准分子激光原位角膜磨镶术(LASIK)术后视力及屈光状态的改变。方法:选择行LASIK手术的超高度近视患者31例54眼,术前屈光度介于-10.00～-17.00D之间,分别测量术前、术后1d,1wk;1,3及6mo的视力、球镜度数、柱镜度数及其轴向并对所得结果进行回顾性分析。结果:超高度近视LASIK术后平均视力较术前增加,球镜度数随时间推移呈下降趋势,至术后6mo尚未达到稳定,术后散光随时间推移逐渐减少,术后散光的轴向可发生一定的变化。结论:认真分析术前资料,科学的设计切削参数,LASIK矫治超高度近视是安全有效的。