Glandular odontogenic cyst: a report of four cases

A glandular odontogenic cyst is a developmental cyst that is a clinically rare and histopathologically unusual type of odontogenic cyst. In this article, we describe four cases of glandular odontogenic cyst. Glandular odontogenic cyst was defined as a well-defined unilocular lesion on panoramic radiographs and multidetector computed tomography. Furthermore, the connection of the cyst to the periodontal tissue was one of the common features of the four cases. The results of the present study indicate the clinical and imaging features of glandular odontogenic cyst.     

数字化改良式与传统基托式塞治器在下颌骨开窗减压术中的对比研究

目的比较数字化改良囊腔塞治器与传统基托式囊肿塞治器在下颌骨囊肿开窗减压术后的临床运用及治疗效果。方法选取下颌骨囊肿开窗减压术后病例37例,随机分为数字化改良囊腔塞治器组和传统基托式囊肿塞治器组,对比两组所用塞治器的技工制作和临床操作用时、戴用后满意度评分及12个月后囊腔大小变化差异。结果数字化改良囊腔塞治器组塞治器的技工制作和临床操作平均用时与传统基托式囊肿塞治器组差异具有统计学意义(P=0.00);数字化改良囊腔塞治器组戴用塞治器后舒适度及清洁度的满意度评分与传统基托式囊肿塞治器组差异具有统计学意义(P<0.05),但两组对固位的满意度评分差异无统计学意义(P>0.05);数字化改良囊腔塞治器组与传统基托式囊肿塞治器组戴用塞治器12个月后囊腔明显减小,但两组间差异无统计学意义(P>0.05)。结论下颌骨囊肿开窗减压术后运用数字化改良囊腔塞治器和传统基托式囊肿塞治器均可取得良好的效果;数字化改良囊腔塞治器具有较高的时效性,患者满意度高,可作为下颌骨开窗减压术后的一种优选治疗装置。     

Recurrent botryoid odontogenic cyst (lateral periodontal cyst)

The terms botryoid odontogenic cyst and lateral periodontal cyst have both been used to describe a histologically distinct type of cyst characterized by a thin epithelial lining exhibiting focal thickenings or plaques. The cyst reported herein is a well-documented example of this type of cyst, which exhibited persistent and recurrent behavior.     

Identification and quantitation of carbohydrates in fluid from non-keratinizing jaw cysts

abstract – Glucose, mannose, galactose, glucosamine, and fucose were detected by paper or thin-layer chromatography, and N -acetylneuraminic acid (sialic acid) was identified by absorption spectroscopy in acid hydrolysates of pooled cyst fluid. Quantitation of these monosaccharides in 37 frozen-stored cyst fluids and autologous sera showed that the average content of hexoses, hexosamine, and sialic acid in cyst fluid approximated that in serum, whereas cyst fluid contained significantly more fucose than did serum. Fifteen of the cyst fluids and samples of autologous serum were also analyzed for free glucose. A mean cyst fluid to serum concentration ratio of 0.48 was found. The results show that the sugar components bound to proteins are the same in cyst fluid and serum. High levels of fucose in cyst fluid indicate the presence of fucomucins.     

Statistical observations on jaw cysts in Enugu, Nigeria, 1987-1996.

Cases of jaw cysts treated at the Department of Oral and Maxillofacial Surgery in the University of Nigeria Teaching Hospital, Enugu during the 10 year period between 1987 and 1996 were studied clinically. A diagnosis of jaw cyst was established in 20 patients during the above period. According to pathological classification by the WHO method, these patients included 10 (50%) with dentigerous cyst, 3 (15%) with radicular cyst, 3 (15%) with odontogenic keratocyst, 3 (15%) with fissural cyst (nasopalatine duct cyst, nasoalveolar cyst, globulomaxillary cyst), 1 (5%) with dermoid cyst. Patients with dentigerous cyst, which was found at relatively high frequency, were further analyzed with regard to age, sex, and anatomical distribution. Among patients with dentigerous cyst, those aged between 21 and 40 years accounted for 60%. Males outnumbered females in a ratio of 1.5:1. Dentigerous cyst occurred most frequently in the region of the mandibular wisdom teeth. The relatively very small number of cases, the need for more research on the subject and the need to educate the general public on oral hygiene are highlighted.     

颌面颈部囊肿囊液细菌与感染的关系

探讨颌面颈囊肿囊液中的细菌与囊肿感染的关系。方法　对 96例口腔颌面颈部各类囊液充盈的囊肿手术时抽出囊液立即作细菌培养 ,进行囊壁完整与破损、颌骨囊肿与面颈囊肿、囊肿大小的细菌培养阳性率的比较。结果　 96例囊肿中 ,细菌培养阳性者 37例 ,其中牙源性囊肿 2 2例 ,非牙源性囊肿 1例 ,面颈囊肿 14例。囊肿完整者与破损者 ,颌骨囊肿与面颈囊肿细菌培养阳性率均无显著性差异 (P>0 .0 5 ) ,但大于 3cm囊肿的细菌培养阳性率明显多于小于 3cm的囊肿 (P<0 .0 5 )。结论　颌面囊肿囊液中有一定数量的细菌存在 ,其中部分细菌对囊肿的感染与增大有一定的关系。     

Huge growth potential of the nasolabial cyst

Two cases of nasolabial cyst are reported. The first case demonstrates the typical features of this rare soft-tissue developmental cyst. In the second case a huge cyst caused severe facial deformity. This case demonstrates the huge growth potential of the nasolabial cyst.     

Treatment of jaw cysts with an irrigational method. (II). The effect on the nature of cyst walls and surrounding bone

Cysts in jaws are generally excised by Partsch II when they are small. When they are large, they are excised by Partsch I to form a paranasal sinus in an oral cavity, or by an operation based on Caldwell-Luc's method to form it from nostrils, as Partsch II forms dead space after the operation and the cyst increases by the pressure of intracystic fluid. However, with Partsch I, the bone needs many days to regenerate, and since a surgical ciliated cyst of the maxilla is often formed after an operation of the maxillary sinus, Partsch I is not necessarily a good method. Therefore, in order to control cyst inflammation, the irrigation of cyst cavities was repeated, as it is held that prostaglandin-like (PG-like) substances are generated in the cyst walls when a cyst is inflamed by bacterial infection; prostaglandin E2 (PGE2) especially acts on the resorption of bone and enlarges the cyst. As a result of repeated irrigations, infection of the cyst cavities disappeared simultaneously with decreasing the pressure of intracystic cavities, the values of thiobarbituric acid, Prostaglandin E, Prostaglandin F2 alpha (TBA, PGE, PGF2 alpha), and the free radical intensity at g = 2.003 decreased. The bone regenerated around the cyst walls, and finally the cyst diminished in size. In the case of the viscous cyst fluids, a solution containing hyaluronidase enabled complete disappearance. It would be better to apply Partsch II after the cyst has become smaller through irrigation. After the irrigational method, irregular formation and tendency toward malignancy could be found in none of the cyst wall cells.     

Ki-67 expression in dentigerous cysts, unicystic ameloblastomas, and ameloblastomas arising from dental cysts

This study investigated whether or not an ameloblastoma developing in the wall of a dentigerous cyst is a distinct lesion from the unicystic ameloblastoma. An immunohistochemical evaluation of Ki-67 in dentigerous cysts, unicystic ameloblastomas, and ameloblastomas arising in dentigerous cysts was done. The values of Ki-67 positivity were 3.14 for the dentigerous cyst, between 5.32 and 16.56 for unicystic ameloblastoma, and 11.77 for ameloblastoma arising in a dentigerous cyst. Statistically significant differences were found between the dentigerous cyst and the unicystic ameloblastoma and between the dentigerous cyst and the ameloblastoma arising from a dentigerous cyst. No statistically significant difference was present between unicystic ameloblastoma and ameloblastoma arising from dentigerous cyst. These immunohistochemical data confirm the hypothesis that an ameloblastoma arising from a dentigerous cyst has a similar biological behavior to the unicystic ameloblastoma and should be considered as merely a histologic variant.     

Human vaginal epithelium and the epithelial lining of a cyst model constructed from it: a comparative light microscopic and electron microscopic study.

The light microscopic features and keratin filament distribution of human vaginal epithelium resemble those of buccal mucosa. We used vaginal epithelium to establish a human cyst model in immunodeficient mice. To strengthen the view that this experimental cyst is a suitable model to study mucosal diseases, we compared specific light microscopic and ultra-structural features of vaginal epithelium and the epithelial lining of the cyst. Nineteen cyst walls and 6 specimens of vaginal mucosa, which had been used to establish the cysts, were examined. We counted the number of cell layers of 17 cyst linings and the 6 vaginal specimens. Surface keratinisation was evaluated on sections stained with the Picro-Mallory method. To demonstrate intercellular lamellae and membrane coating granules 2 cyst linings were examined ultra-structurally. The epithelium lining of the cyst wall was thinner than that of vaginal mucosa but the surface keratinisation and ultra-structural features of the intercellular lamellae and membrane coating granules were similar. We concluded that vaginal mucosa is a useful substitute for oral mucosa in the cyst model.     

Lymphoepithelial cyst of the upper neck: report of a case

A case of lymphoepithelial cyst of the upper neck is presented. The patient was a 77-year-old woman. After her lesion was extirpated under clinical diagnosis of salivary gland tumor, identified as lymphoepithelial cyst (so-called branchial cyst). Histopathologically salivary gland was observed in the cyst wall composed of lymphoid tissue and was demonstrated highly active amylase-enzyme (S type) in the cyst fluid. These findings are convicted that our case originates ductal epithelium entrapped in cervical lymph node (inclusion theory of Bhaskar).     

Aneurysmal bone cyst associated with a dentigerous cyst: report of case

An aneurysmal bone cyst associated with a dentigerous cyst filled the entire maxillary right sinus and corresponding eroding portions. The report discusses the unusual presence of a dentigerous cyst, documentation of an aneurysmal bone cyst associated with a primary lesion, and offers suggestions as to the common pathogenesis of the two lesions.     

Dentigerous cyst associated with permanent central incisor: a rare entity

Dentigerous cyst is one of the most prevalent types of odontogenic cyst and is associated with crown of an unerupted or developing tooth. Dentigerous cyst is more commonly seen with mandibular third molar and maxillary canine and rarely other teeth are involved. Here we report a case of dentigerous cyst involving permanent maxillary central incisor.     

Calcifying odontogenic cyst presenting as a lateral periodontal cyst--a case report

We report a case of the calcifying odontogenic cyst occurring on the left anterior mandible of a 41-year-old male with clinical and radiographic features which made it initially to be a lateral periodontal cyst. This unusual presentation of a calcifying odontogenic cyst is discussed and its significance for the clinician is reviewed. A calcifying odontogenic cyst may present some problems for the differential diagnosis both clinically and histopathologically. The differential diagnosis of a lesion occurring in a lateral periodontal location should include the calcifying odontogenic cyst.     

舌下腺囊肿的诊断与鉴别诊断

舌下腺囊肿是一种常见的唾液腺黏液囊肿,临床上分为单纯型、口外型和哑铃型。舌下腺囊肿的临床诊断主要根据其临床特征、影像学检查、囊肿内容物检查和组织学检查等。口外型舌下腺囊肿因其异常的发生部位而易被误诊,需同多种颈部肿物相鉴别。文章就舌下腺囊肿的诊断与鉴别诊断做一概述。     

60例甲状舌管囊肿临床分析

目的探讨甲状舌管囊肿临床流行病学特点以提高手术治疗效果。方法对60例甲状舌管囊肿的临床表现、病理特点和治疗效果进行回顾性分析。结果甲状舌管囊肿以儿童好发,女性多于男性,舌骨及舌骨以下水平多见;多数甲状舌管囊肿位于颈正中线附近,极少数表现为颌下囊肿;囊肿以单个为主,少数表现为多个囊肿;多数病例术后可探查到管状物或条索状物。甲状舌管囊肿病理组织学表现呈多样性特征,治疗不当易复发。结论甲状舌管囊肿的临床表现及病理特点均表现为多样性特征,手术不当易复发。     

Primary cilia in the pathogenesis of dentigerous cyst: a new hypothesis based on role of primary cilia in autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD), an inherited disease, leads to cyst formation in the kidneys. In this condition, the kidneys are grossly enlarged with multiple cysts that result in kidney failure in a majority of individuals. This condition is also associated with cysts in other organs. Recent research has focused on defects in signaling mediated by the primary cilia as the causative factor in ADPKD. Primary cilia are also present in odontogenic epithelium. Dentigerous cyst also is a developmental cyst whose pathogenesis is controversial. Recent studies have shown that loss of Ptch and Shh signaling pathways are involved in the cystogenesis of dentigerous cyst. The Shh signaling pathway is active in the primary cilia. A scanning electron microscopic study of a dentigerous cyst wall in an ADPKD patient showed structures similar to primary cilia. Based on the presentation of a dentigerous cyst in an autosomal dominant polycystic kidney patient and the demonstration of primary cilia like structures on the cyst wall by using a scanning electron microscope, a new hypothesis for the pathogenesis of dentigerous cyst is proposed.     

3D打印负压引流囊肿塞在下颌骨囊性病变开窗减压术后应用效果研究

目的    设计一种3D打印的具有负压引流功能的囊肿塞,评价其在下颌骨囊性病变开窗减压术后应用的临床效果。方法    选取2018年8月至2019年12月于西南医科大学附属医院口腔颌面外科、泸州市人民医院口腔科就诊的下颌骨囊性病变患者18例,随机分为3D打印组和传统组,每组9例。所有患者均采用开窗减压术治疗,3D打印组使用3D打印的负压引流囊肿塞,传统组使用传统义齿型囊肿塞。术后1、3、6个月,评价两组患者主观评价指标、囊腔体积缩小率及囊腔长径变化情况。结果    术后1个月,对两组患者的主观评价指标进行比较分析发现,相较于传统组,3D打印组患者对囊肿塞的舒适性评价较高,且认为更易清洁囊腔,差异有统计学意义（均P < 0.05）;两组患者对囊肿塞的固位性和使用便利性评价比较,差异无统计学意义（均P > 0.05）。术后3、6个月,3D打印组囊腔体积缩小率均大于传统组,差异均有统计学意义（均P < 0.05）;但两组囊腔长径变化量比较,差异均无统计学意义（均P > 0.05）。结论    3D打印负压引流囊肿塞小巧舒适,清洁囊腔效果好,能够加速囊腔缩小,建议在颌骨囊性病变开窗减压术后应用。