彩色三维多普勒超声在心搏出量计算方面的实验性研究

目的探讨彩色三维多普勒超声在心搏出量计算方面的应用价值.方法运用彩色三维多普勒超声对10只犬先后在三种状态下,即静息状态下正常心搏出量、注射多巴酚丁胺时的高心搏出量和结扎左冠状动脉前降支后出现的低心搏出量进行检查,测定犬在不同状态下通过主动脉瓣口横断面血流积分及心搏量的变化,并与热稀释法测定的数值比较.结果彩色三维超声计算犬在不同心功能状态下的每搏量与生理仪热稀释法测得相应的数值相关显著,其中①静息状态下正常心搏出量时两种方法测值分别为(13.45±5.56)ml与(13.90±4.02)ml,r=0.85;②注射多巴酚丁胺后高心搏出量时分别为(18.49±4.73)ml与(19.10±4.37)ml,r=0.90;③结扎冠脉后低心搏出量时分别为(10.24±4.13)ml与(11.31±3.92)ml,r=0.92.彩色三维超声与生理仪热稀释法两种方法所测定的心搏出量非常接近,总相关系数r=0.93,t检验差别无显著性意义.结论彩色三维多普勒超声在理论上不存在几何学方面的假设,可直接测量经过瓣口的血流量,是一项很具潜力的超声新技术.     

三维彩色多普勒超声计算每搏动能评价心功能的临床研究

目的探讨运用三维彩色多普勒超声心动图计算每搏动能进行心功能评价的临床价值.方法 40例受检者均经体检、X-线检查、心电图及超声心动图证实为健康人.30例冠状动脉粥样硬化性心脏病患者均经冠状动脉造影证实存在冠状动脉狭窄(狭窄程度>75%).利用Tom Tec三维彩色多普勒成像工作站进行心脏三维图像获取和重建,以三维彩色多普勒重建图像测量收缩期通过主动脉瓣短轴平面的血流速度和血流量;在此基础上计算出心脏每搏动能(KE).采用t检验对健康者和冠心病患者的KE测值进行比较,P ＜0.05为有统计学意义.结果健康者的KE为(0.66±0.13)g-m,冠心病患者的KE测值为(0. 23±0.16)g-m;冠心病患者的每博动能较健康者明显降低(P＜0.05).结论利用三维彩色多普勒超声心动图的血流测值可以计算出心脏KE,KE 能够用于心脏泵血功能的临床评价.     

多巴酚丁胺负荷超声心动图结合组织多普勒成像诊断冠心病

目的探讨多巴酚丁胺负荷超声心动图(DSE)结合组织多普勒成像(TDI)在冠心病(CHD)诊断中的应用价值.方法选择胸闷或胸痛怀疑CHD的患者50例,应用TDI测量静息状态下以及多巴酚丁胺峰值负荷状态下左心室前壁中段收缩峰值速度(Vs),所有入选对象均进行冠状动脉造影,并根据左前降支狭窄程度是否≥50%分为左前降支狭窄组(LST组,17例)与左前降支非狭窄组(non-LST组,20例).结果左心室前壁中段Vs在静息状态下LST与non-LST组比较差异无统计学意义(P＞0.05),在多巴酚丁胺峰值负荷状态下差异有非常显著性(P＜0.01),且Vs增加幅度2组相比差异也有非常显著性(P＜0.01).结论DSE结合TDI是诊断CHD有价值的定量分析方法,DSE在诊断CHD时的敏感性、准确性明显优于静息状态超声心动图.     

三维彩色多普勒超声对扩张性心肌病心搏出量的研究

目的 :运用三维彩色多普勒超声计算扩张性心肌病患者心搏出量 ,探讨彩色三维超声在左室扩张变形时的应用价值。方法 :扩张性心肌病患者 9例 ,男 6例 ,女 3例 ,以二维 M-型超声心动图计算左室射血分数(EF)、短轴缩短率 (FS)及每搏量 (SV) ;运用三维彩色多普勒超声仪对患者主动脉瓣口血流进行三维重建 ,计算每搏量并与二维超声测值比较。结果 :二维超声测值 EF:2 8.2 %± 3.8% ,FS:1 3.7%± 1 .9% ,每搏量 :(56.1± 1 0 .4) ml;三维超声测值每搏量 :(47.5± 1 2 .8) ml。二维与三维超声的每搏量测值 t检验无显著性差异。结论 :彩色三维超声心动图可不受左室形变及二尖瓣返流的影响 ,能较准确地评价扩张性心肌病患者的每搏量及心功能状况     

三维彩色多普勒超声心动图评价心脏收缩功能的实验研究—无创测量心脏每搏动能的准确性

评价三维彩色多普勒超声心动图测量心脏每搏动能的可行性。方法实验动物选用犬10只,体重10.5～20.5kg。左前胸进行彩色多普勒超声心动图探查,并利用TomTec三维彩色多普勒成像工作站进行三维图像获取和重建,利用三维彩色多普勒重建图像测量收缩期通过主动脉瓣瓣口的血流速度(V)和血流量(Q);根据V和Q计算出心脏每搏动能EK＝1/2     

二维及三维彩色我普勒超声心动图在心搏出量计算方面的实验性研究

目的比较二维超声及三维彩色多普勒超声在心搏出量计算方面的准确性。方法运用M超Teichholtz公式法、双平面Simpson公式法、主动脉血流频谱积分与瓣口面积相乘法以及彩色三维多普勒超声计算10只犬在静息状态及结扎左冠状动脉前降支后通过主动脉瓣口的流量变化,并与热稀释法测定的数值比较。结果冠脉结扎前后彩色三维超声计算的犬每搏量与生理仪热稀释法测得相应的数值相关显著,其中静息状态下r＝0.85,结扎冠脉后r＝0.92,t检验无显著性差异;二维超声计算的心搏出量在基态时与生理仪热稀释法测值相关较好,Teichholtz公式法、Simpson法、Doppler频谱法与热稀释法测值的相关系数分别为0.96、0.85、0.95;t检验示Teichholtz公式法及Simpson法的测值与热稀释法测值无显著性差异,Doppler频谱法的测值与热稀释法测值相差显著(P＜0.01)。冠脉结扎后Teichholtz公式法的测值与热稀释法数值无显著相关,r＝0.68;Simpson法及Doppler频谱法测值的相关系数分别为0.86和0.91;t检验示Simpson法测值与热稀释法测值无显著性差异,其余两组数值与热稀释法相差显著(P＜0.01)。结论彩色三维多普勒超声在理论上不存在几何学方面的假设,可不受节段性室壁异常运动的影响,准确地计算心搏出量的变化。     

实时三维超声心动图评价多巴酚丁胺对心肌顿抑和梗死犬左心室局部径向距离的影响

目的应用实时三维超声心动图(RT-3DE)定量评价多巴酚丁胺对心肌顿抑犬和心肌梗死犬左心室局部径向距离的作用。方法建立犬的心肌顿抑[冠状动脉(冠脉)结扎15 min,再灌注30 min]和急性心肌梗死(冠脉结扎180 min,再灌注30 min)模型。于冠脉结扎前和冠脉结扎-再灌注后,用微量输液泵经股静脉输注多巴酚丁胺5及10μg.kg-1.min-1,每一剂量持续5 min。应用RT-3DE获取实验犬静息状态及输注多巴酚丁胺10μg.kg-1.min-1后RT-3DE全容积数据库。脱机后,根据心尖长轴观8平面法重建收缩末期左室立体几何形状;以二尖瓣环中点至左室心尖部心内膜的连线为中心轴,将左室等分成与中心轴垂直的1.0 cm厚互相平行的短轴平面,从中选取室壁运动异常(WMA)面积最大者作为研究平面;在此平面上,以轴心与左室后壁连线所在位置为0°,逆时针每隔20°测量心内膜至轴心的距离(即径向距离R,共可测得18个值)。将冠脉结扎-再灌注后两组实验犬输注多巴酚丁胺前、后的平均R值与冠脉结扎前(设为基础状态)输注多巴酚丁胺前、后的相应R值进行比较。结果静息状态下,心肌顿抑组和心肌梗死组中所选研究平面结扎冠脉供血区平均R值均明显增大(均P<0.001)。输注多巴酚丁胺后,心肌顿抑组中上述异常增大的平均R值均明显减小(均P<0.001),但未恢复至基础状态水平(均P<0.05);心肌梗死组中上述异常增大的平均R值均无明显改变(均P>0.05)。结论通过应用RT-3DE分析输注多巴酚丁胺前、后左室局部径向距离的变化,可以识别心肌顿抑和心肌梗死。RT-3DE有望为临床定量评价左室局部几何形状提供一项有效手段。     

经食管多巴酚丁胺负荷多普勒超声心动图检测冠状动脉血 …

目的 探讨经食管多普勒超声心动图多巴酚丁胺负荷试验评价冠心病及高血压患者的冠脉血流储备的临床价值。方法 将４９例受试者分为对照组Ａ１组;冠脉造影正常但有高血压的Ａ２组;冠脉中度狭窄的Ｂ组;冠脉重度狭窄的Ｃ组,测定注射多巴酚丁胺前后冠脉左前降支内舒了大血流速度、舒张期平均血流速度;并进行室壁运动分析。结果 注射多巴酚丁胺前后冠脉左前降支内张期厚大血流速度、舒张期平均血流速度;并进行室壁运动分析。结果     

不同剂量多巴酚丁胺对正常心肌纵向收缩期峰值应变的影响

目的 探讨不同剂量多巴酚丁胺对正常人纵向收缩期峰值应变的影响.方法 对11例冠状动脉造影正常或狭窄＜50％的正常人,进行大剂量多巴酚丁胺负荷试验.分别在静息状态、5、10、20、30和40 μg/ (kg·min)测定左室各心肌节段心内膜下心肌的纵向收缩期峰值应变并进行统计学分析.结果 在静息状态下及各级负荷状态下左室心肌纵向收缩期峰值应变从基底段至心尖段逐渐增加.在心尖段,后间隔和下壁的纵向收缩期峰值应变值大于其他节段;在中间段,下壁和前间隔的纵向收缩期峰值应变值大于其他节段;在基底段,前壁和后壁的纵向收缩期峰值应变值大于其他节段.多巴酚丁胺负荷试验中,心肌各节段的纵向收缩期峰值应变值随着多巴酚丁胺剂量的增加而增加,大多数节段在多巴酚丁胺剂量20 μg/ (kg·min)时达到峰值,个别节段多巴酚丁胺剂量30 μg/ (kg· min)时达到峰值,峰值纵向收缩期峰值应变与同组静息状态比较,差异有统计学意义(P＜0.05);多巴酚丁胺剂量40 μg/ (kg·min)时,大多数节段纵向收缩期峰值应变与静息状态比较轻度下降,个别节段稍增高,差异无统计学意义(P＞0.05).结论 正常心肌节段的纵向收缩期峰值应变随着多巴酚丁胺负荷剂量的增加而增加,但当剂量达到40 μg/ (kg·min)时,开始恢复到静息水平或有所降低.     

多巴酚丁胺负荷三维超声心动图检测法洛氏四联症根治术前左心室容积与功能

本文应用多巴酚丁胺负荷三维超声心动图研究法洛氏四联症(TOF)根治术前左心室舒张末期容积(LVVd),收缩末期容积(LVVs)、射血分数(LVEF).研究对象:患儿组25例(男14、女11),年龄1.00～11.50(4.50士2.69)岁;对照组8例(男6、女2),年龄1.29～14.83(8.39土4.14)岁.结果:TOF根治术前左心室舒张末期容积指数(LVEDVI)小于正常,静息状态LVEF正常;多巴酚丁胺负荷试验(DST)中,LVVd最大增大率、LVVs最大缩小率、LVEF最大增高率TOF组明显低于正常.结论:TOF根治术前左心室发育不良,静息状态射血功能正常,DST揭示出TOF根治术前潜在的左心功能贮备减低.     

Longitudinal fractional shortening and its relation to diastolic cardiac function

Purpose  Although alterations in longitudinal systolic function have been considered the earliest sign of cardiac damage, the importance of longitudinal fractional shortening (LFS), which reflects left ventricular longitudinal contraction, has not been studied in detail. We introduce a new method of measuring LFS by echocardiography and evaluate its efficiency. Methods  Our study population consisted of 120 patients with diabetes mellitus (DM), 29 healthy volunteers, and 12 patients with coronary artery disease (CAD). LFS was assessed echocardiographically. Patients with DM underwent conventional echocardiography, assessment of left ventricular diastolic function, and pulsed-wave tissue Doppler study. Results  LFS was 0.07 ± 0.02 in patients with CAD, 0.16 ± 0.05 in patients with DM, and 0.26 ± 0.04 in the normal controls. The three groups differed significantly with respect to the mean LFS values, which were significantly lower in patients with DM than in the normal controls. The ratio of peak diastolic velocities during early filling and atrial contraction (Em/Am) measured on pulsed-wave tissue Doppler images was significantly correlated with LFS (r = 0.37, P < 0.0001). Conclusion  LFS is correlated with diastolic cardiac function and is a useful and sensitive index for evaluating long-axis systolic function.     

实时三维超声心动图评估射血分数减低的左心力衰竭患者的右心室重构

目的 采用单心动周期实时三维超声心动图(sRT-3DE)结合传统二维超声心动图探讨左心室射血分数(LVEF)减低的左心力衰竭患者肺高压(PH)对右心室重构的影响。方法 对sRT-3DE检查LVEF<50%的60例患者(病例组)根据肺动脉收缩压(PASP)及肺血管阻力(PVR)不同分为3个亚组:HF-NPH亚组15例,HF-PPH亚组15例,HF-RPH亚组30例,正常健康人35名为对照组。对两组行常规二维超声及sRT-3DE检查,分析获得三维、二维及多普勒超声参数,进行组间对比分析和相关性分析。结果 与对照组比较:病例组右心室舒张末期容积指数(EDVI)、收缩末期容积指数(ESVI)、基底部横径(D1)、长径(LD)、D1/中间横部径(D2)、射血分数(EF)减小。与HF-NPH亚组比较,HF-PPH亚组右心室ESVI、D1/D2、LD/D2增大。与HF-PPH亚组比较,HF-RPH亚组右心室EDVI、ESVI、D2增大,右心室EF、LD/D2减低。PVR与PASP、右心室EF与左心室EF、右心室LD与左心室LD呈正相关性(r=0.765、0.628、0.725;P均<0.01),PVR与右心室EF呈负相关(r=-0.715,P<0.01),且高于与PASP的相关性(r=-0.623,P<0.01)。结论 sRT-3DE结合传统二维及多普勒超声可准确评估左心力衰竭患者的右心室重构,有助于判断右心室结构和功能状态。     

组织多普勒评价2型糖尿病患者左、右心室功能

目的 评价2型糖尿病患者左、右心室的收缩和舒张功能,为糖尿病性心肌病的早期预防和诊断提供可靠依据.方法 通过彩色和组织多普勒对50例2型糖尿病患者和30名正常受试者左、右心室的收缩和舒张功能进行研究.利用相关分析检验左、右室功能之间可能存在的相关性.结果 2型糖尿病患者的左、右心室舒张功能受损,但左、右心室整体收缩功能保留;左心室和右心室功能的参数之间存在显著相关性.结论 2型糖尿病患者在出现心肌收缩功能异常前已有左、右心室舒张功能的损害,这些功能的改变可能与心室的相互依赖和糖尿病对心脏功能的等同作用有关.     

早期新生儿脉冲组织多普勒超声心动图的研究

目的 探讨脉冲组织多普勒技术评价早期新生儿心功能并了解心动周期中各时间间期及其随心率的变化规律.方法 86例出生2天、3天、4天新生儿,采用TDI技术检测早期新生儿二、三尖瓣环运动,测量收缩期峰值速度(Sa),舒张早期峰值速度(Ea)与舒张晚期峰值速度(Aa)比值(Ea/Aa),E与Ea比值(E/Ea),以及TDI频谱各时间间期.分别以日龄和性别分组,比较组间以及左右室之间上述各指标差异性,并进行时间间期与心率的相关性分析.结果 Sa、Ea/Aa及E/Ea在不同H龄间差异均无显著性(P＞0.05).男性新生儿与女性二尖瓣环左室侧Ea/Aa(0.89±0.31 vs 1.09±0.29,P=0.005)及E/Ea(10.98±2.24 vs 9.38±2.62,P=0.008)、三尖瓣环与二尖瓣环Sa(5.74±0.10 vs 4.30±0.93,P=0.000)、Ea/Aa(0.85±0.25 vs 1.00±0.32,P=0.003)及E/Ea(7.22±2.42 vs 10.09±2.57,P=0.000)差异均有显著性.各时间间期在不同口龄组间差异无显著性;男性新生儿与女性左室总舒张时间(207.14±34.70 vs 230.00±48.16,P=0.013)差异具有显著性;除外舒张后期时间,所有时间间期指标左右室间差异均有显著性(P＜0.01).新生儿收缩时间与舒张时间之比约0.54/0.46.心率与舒张早期时间、舒张后期时间强负相关(r=-0.547,-0.687).与心房收缩时间无相关关系,而与等容收缩时间,射血时间均弱负柑关(r=-0.280,-0.374).结论 早期新生儿心功能日龄间无差异;女性新生儿的心室舒张功能优于男性,而收缩功能无性别差异.左室舒张时间男性新生儿短于女性;右室的收缩早于左室,并且右室的收缩时间比左室长.心率增快主要影响舒张后期时间和舒张早期时间,与心房收缩时间无相关关系.     

不同模式超声心动图对乳腺癌化疗患者左心室收缩功能的早期诊断价值

目的：评价单心动周期实时全容积三维超声心动图、M型超声心动图及二维双平面Simpson法对乳腺癌化疗患者不同化疗周期左心室收缩功能动态监测的价值。 方法：搜集于我院规范化疗女性乳腺癌患者39例,用单心动周期实时全容积三维超声心动图、M型超声心动图以及二维双平面Simpson法测量患者术前及不同化疗周期（6个化疗周期）左室舒张末容积、左室收缩末容积和左室射血分数,分析比较不同化疗周期左心室收缩功能指标的变化。 结果： 1、随着化疗药物累积剂量的不断增加,第6化疗周期开始M型超声心动图结果显示左心室射血分数开始下降(61.59±2.12%),与术前比较（68.40±2.07%),差异具有统计学意义(P<0.05);第6化疗周期开始二维双平面Simpson法结果显示左心室射血分数开始下降（59.94±2.98%),与术前比较（66.71±2.03%)(P<0.05),差异具有统计学意义;第5化疗周期开始单心动周期实时全容积三维超声心动图结果显示左心室射血分数开始下降（56.87±2.18%),与术前比较（64.54±1.92%),差异具有统计学意义(P<0.05)。 2、随着化疗药物累积剂量的不断增加,二维双平面Simpson法、单心动周期实时全容积三维超声心动图结果显示不同化疗周期左室舒张末容积与术前比较,差异均无统计学意义(P>0.05)。 结论：乳腺癌患者随着化疗药物累积剂量的不断增加,会出现左心室收缩功能减低,单心动周期实时全容积三维超声心动图能较M型超声心动图及二维双平面Simpson法更早发现左心室收缩功能指标射血分数减低,能更早发现亚临床左心室收缩功能不全,应于第5化疗周期开始对心脏功能进行重点监测,以便及早发现亚临床左心室收缩功能不全。     

Evaluation of left atrial systolic function in noncompaction cardiomyopathy by real-time three-dimensional echocardiography

Background Noncompaction cardiomyopathy (NCCM) is a rare disorder with persistance of the embryonic pattern of myoarchitecture. NCCM is characterized by loosened, spongy myocardium associated with a high incidence of systolic and diastolic left ventricular (LV) dysfunction and heart failure (HF). It is known that LV dysfunction contributes to elevated left atrial (LA) and pulmonary vascular pressures, however atrial function has not been examined in NCCM. The objective of the present study was to assess LA systolic function characterized by LA ejection force (LAEF) in NCCM patients using real-time three-dimensional echocardiography (RT3DE) and to compare to control subjects. Methods The study comprised 17 patients with an established diagnosis of NCCM and their results were compared to 17 healthy age-matched controls with no evidence of cardiovascular disease. Forty-one percent of NCCM patients were in NYHA functional class II / III HF. Previously proposed echocardiographic diagnostic criteria for NCCM were used. All patients underwent conventional two-dimensional echocardiography and RT3DE. LAEF was measured based on MA annulus diameter (LAEF_3D-MAD) and area (LAEF_3D-MAA) using RT3DE. Results The presence and severity of mitral regurgitation were more frequent in NCCM patients than in control subjects. LV diameters and mitral annulus were significantly increased in NCCM patients. Compared with control subjects, both LAEF_3D-MAD (3.8 ± 2.2 vs 2.3 ± 1.0 kdyne, P < 0.05) and LAEF_3D-MAA (12.7 ± 7.6 vs 4.9 ± 2.1 kdyne, P < 0.01) were significantly increased in NCCM patients. Conclusions LAEF as a characteristic of LA systolic function is increased in NCCM patients compared to normal individuals. These results can suggest compensating left atrial work against the dysfunctional LV in NCCM patients.     

Age-dependency of left ventricular filling dynamics and relaxation as assessed by pulsed Doppler echocardiography

Summary. Left ventricular diastolic function was assessed from transmitral flow velocity curves as measured by Doppler echocardiography in healthy individuals aged 21–69 years, each decade comprising 12 subjects. By ageing, progressive changes in the various filling parameters were observed. When comparing the youngest and oldest age groups, the ratio between peak velocities in early and late diastole decreased from 2.0±0.3 to 1.2±0.3 (P<0.001). The filling fraction of first third of diastole decreased from 54 ± 5% to 45 ± 4% (P<0.001). Isovolumic relaxation time increased from 61 ± 11 ms to 77 ± 12 ms (P<0.01). Correlation coefficients of velocity ratio, filling fraction and isovolumic relaxation time vs. age were r= -0.71 (P<0.001), r= -0.56 (P<0.001) and r= 0.44 (P<0.001), respectively. When isovolumic relaxation time and age were used together in multivariate regression analysis, only age was an independent predictor of velocity ratio and filling fraction. Stroke volume, peak velocity in left ventricular outflow tract, heart rate and systolic blood pressure were similar in all age groups. Thus, velocity ratio and filling fraction indicated a relative filling shift towards late diastole by ageing and were more sensitive than s?ystolic parameters in reflecting age-related changes in cardiac function. The changes could be explained neither by delayed relaxation nor by change in systolic parameters. When using Doppler echocardiography for evaluation of left ventricular filling, agematching of reference groups is necessary.     

Evaluation of left atrial functions by color tissue Doppler imaging in adults with body mass indexes ≥30 kg/m<Superscript>2</Superscript> versus those <30 kg/m<Superscript>2</Superscript>

Evaluation of atrial function has received less attention than that of the ventricle although normal atrial function is required for optimal overall cardiac function. Obesity is associated with increased cardiovascular morbidity and mortality. In this study, we compared left atrial functions in obese adults (body mass index = BMI ≥30 kg/m²) with those in non-obese adults (BMI <30 kg/m²) by color tissue Doppler parameters. There were 37 adults with BMI ≥30 kg/m² (mean age 36 ± 11 years) and 26 adults with BMI <30 kg/m² (mean age 35 ± 5 years). Mean BMI was 38 ± 6 kg/m² in the obese group whereas that was 24 ± 2 kg/m² in the non-obese group. For color tissue Doppler imaging, sample volumes were placed on the mid left atrium at the septum, lateral, inferior, and anterior walls. The peak systolic strain (S _s), peak systolic strain rate (SR_s), peak early diastolic SR (SR_e), peak late diastolic SR (SR_a), peak systolic tissue velocity (TV_s), peak early diastolic TV (TV_e) and peak late diastolic TV (TV_a) values were measured. For each measurement, values in three consecutive cardiac cycles were measured and then averaged. To simplify the analysis, the values at each wall were combined and averaged to obtain mean values. All left atrial systolic function parameters (S _s, SR_s, TV_s) were similar between the groups. In addition, there was no statistically significant difference at left atrial diastolic function parameters (SR_e, SR_a, TV_e, TV_a). We could not find any significant difference between obese and non-obese adults at left atrial functions assessed by color tissue Doppler parameters.     

整体长轴收缩期峰值应变率指标评价心肌梗死患者左室收缩功能

目的 探讨整体长轴收缩期峰值应变率指标在评价心肌梗死患者左室整体收缩功能中的应用价值.方法 对14例心肌梗死患者与20例健康对照者,采集心尖两腔、四腔及左室长轴切面二维超声图像,应用VVI技术测量左室各节段收缩期长轴峰值应变率(SRs)并取平均值得出左室整体长轴收缩期峰值应变率(GSRs).以常规二维超声心动图评价左室壁节段运动,计算室壁运动积分指数(WMSI),并应用Simpson双平面法计算左室射血分数(LVEF).应用脉冲波组织多普勒显像(PDTI)技术测量并计算二尖瓣环平均收缩期峰值速度(Sm).比较两组间各指标,评价GSRs指标与WMSI指标、Sm指标及LVEF指标的关系.结果 心肌梗死患者组及正常对照组GSRs、WMSI、Sm及LVEF分别为(-0.57±0.21)%和(-1.02±0.09)%、(1.90±0.80)和(1.10±0.30)、(6.20±1.50)cm/s和(9.80±1.30)cm/s、(32.90±7.10)%和(65.50±5.70)%,差异均有统计学意义(P<0.05),且GSRs与WMSI、Sm及LVEF均呈高度相关(r=0.97,-0.98,-0.93, P<0.0001).结论 GSRs是客观评价左室整体收缩功能的新指标.