LigaSure血管闭合系统在甲状腺良性疾病手术中的应用

目的:探讨LigaSure血管闭合系统在甲状腺良性疾病手术中的应用价值。方法:回顾性分析2012年6月—2014年6月278例因良性甲状腺疾病行手术治疗患者的临床资料,按手术是否使用LigaSure将患者分为LigaSure组(130例)和传统手术统组(148例),比较两组患者的相关临床指标。结果:两组患者术前一般临床资料差异均无统计学意义(均P0.05)。LigaSure组与传统手术组比较,手术切除范围无统计学差异(P0.05),手术时间明显缩短(55.2 min vs.70.8 min,P0.05),术中出血量明显减少(18.1 mL vs.35.2 m L,P0.05),术后常见并发症的发生率及住院时间均无统计学差异(均P0.05)。结论:甲状腺良性疾病手术中使用Liga Sure可简化手术操作,减少手术时间,降低术中出血,值得临床应用。     

PPH联合LigaSure治疗重度环状混合痔48例疗效观察

目的:为观察PPH联合结扎速血管闭合系统(LigaSure)治疗重度环状混合痔的临床效果.方法:将96例重度环状混合痔患者随机分为观察组和对照组,每组48例.观察组采用PPH联合LigaSure痔切除术治疗;对照组行PPH联合超声刀痔切除术治疗.比较2组手术指标、术后并发症及临床疗效.结果:观察组术中出血量、住院时间和...     

改良Miccoli术式与完全内镜术式治疗良性甲状腺结节的临床分析

目的：对比改良Miccoli术式与完全内镜术式治疗良性甲状腺结节的手术效果,为术式选择提供临床依据。 方法：48例良性甲状腺结节患者分别采用改良Miccoli术式（改良Miccoli组,24例）和完全内镜术式（完全内镜组,24例）行甲状腺腺瘤切除术、甲状腺部分切除术、甲状腺次全切除术、单侧甲状腺腺叶切除术。对比分析手术时间、术中出血量、术后疼痛分级、术后引流量、切口满意度、住院时间、住院费用、并发症发生率。 结果：在手术时间、术中出血量、术后疼痛分级、术后引流量方面改良Miccoli组均明显优于完全内镜（均P<0.05）,但切口满意度评分完全内镜组明显高于改良Miccoli组（P<0.05）;两组住院时间、住院费用、并发症发生率差异无统计学意义（均P>0.05）。 结论：改良Miccoli术式治疗良性甲状腺结节有明显优势,可作为优先选择的术式;完全内镜术式适合美学要求较高的患者。     

LigaSure在小切口甲状腺手术中的应用

目的探讨血管闭合器（LigaSure）在小切口甲状腺手术中的应用效果。方法回顾性分析2年间收治的58例良性甲状腺疾病（Ⅱ&#176;）采用颈部小切口及LigaSure下施行甲状腺次全切除术者临床资料。结果手术平均时间45（35～70）min。术中平均出血量15（5～30）mL，术后24h甲均切口引流量20（10～30）mL，术后未出现声嘶及口角麻木等手术并发症。术后平均住院时间3（2～4）d。结论LigaSure在甲状腺手术中的应用较之传统手术能缩短手术时间、减少术中出血量和手术并发症，术后恢复快，手术切口小，不甚影响美观。     

剥离法在改良Miccoli术中的应用体会

目的探讨剥离法在内镜辅助下经颈部小切口行甲状腺切除术（改良Miccoli术）中的应用价值。方法对39例甲状腺良性疾病患者采用剥离法内镜辅助下颈部小切口甲状腺切除术。按传统Miccoli术方式切开、建腔、显露,按剥离法要求游离、超声刀离断腺体,切除病灶。甲状腺瘤12例,其中11例行单侧甲状腺部分切除,1例行单纯峡部肿物切除;结节性甲状腺肿27例,其中13例行双侧甲状腺部分切除7,例行一侧腺叶大部切除加一侧肿瘤切除,5例双侧腺叶大部切除,2例单侧腺叶全切。结果 39例手术均顺利完成,手术切口平均2.4（1.5～3.0）cm,无中转开放手术;手术时间平均59.6（30～135）min;术中出血17.6（10～60）ml;术后第1 d引流量平均8（6～10）ml;术后住院时间平均4.2（3～6）d。术后术野皮下炎性肿胀3例,无喉返神经损伤或甲状旁腺功能低下等并发症。术后均获随访,平均10（6～12）个月,患者局部不适感轻微,颈部瘢痕不明显,美容效果好,复查甲状腺超声未见复发。结论在改良Miccoli术中采用剥离法手术策略简便、安全,并发症少,值得推广。     

纳米炭示踪与改良Miccoli技术在甲状腺乳头状癌全甲状腺切除术中的应用及比较

目的:探讨并比较纳米炭示踪技术与改良内镜辅助甲状腺切除术(Miccoli术)应用于甲状腺乳头状癌(PTC)全甲状腺切除术中的效果及对甲状旁腺功能的保护作用。方法:回顾性分析117例接受全甲状腺切除术PTC患者的临床资料,其中31例术中采用纳米炭标记(纳米炭组),56例采用改良Miccoli手术(Miccoli组),30例采用常规手术(常规组)。比较各组的手术指标、手术前后的血钙与甲状旁腺激素(PTH)水平、术后视觉模拟评分(VAS)与数字评分系统(NSS),以及术后暂时性或永久性喉上神经(SLN)损伤、喉返神经(RLN)损伤、甲状旁腺功能降低、低钙血症及甲状腺癌复发情况。结果:各组患者术前资料具有可比性。Miccoli组手术时间明显长于另两组,但切口长度、术中出血及术后引流量明显少于另两组(均P0.05),各组淋巴结清扫数、术后住院时间无明显差异(均P0.05),但纳米炭组淋巴结受累检出率明显高于常规组(P0.05)。术后1 h至7 d,纳米炭组和Miccoli组血钙及PTH水平明显高于常规组(均P0.05),但前两组间无统计学差异(均P0.05);Miccoli组VAS明显低于另两组,且纳米炭组低于常规组(均P0.05)。术后1个月,各组血钙和PTH水平及VAS均无明显差异(P0.05)。术后3、6个月,Miccoli组的NSS明显低于另两组,而纳米炭组明显低于常规组(均P0.05)。所有患者均获得随访,随访时间为18～41个月。各组SLN损伤率无统计学差异(P0.05);纳米炭组与Miccoli组RLN损伤、甲旁减、低钙血症发生率均明显低于常规组(均P0.05),但纳米炭组与Miccoli组间比较差异无统计学意义(均P0.05);各组的复发率差异无统计学意义(P0.05)。结论:纳米炭与改良Miccoli术用于PTC全甲状腺切除术均能够有效保护患者的甲状旁腺功能,纳米炭技术的淋巴结清扫彻底性更好,而改良Miccoli技术更为微创。     

LigaSure血管闭合系统在腹腔镜脾脏切除术中的应用

目的:探讨LigaSure血管闭合系统在腹腔镜脾脏切除术中的临床应用价值。方法:回顾分析2002年8月至2006年4月利用LigaSure血管闭合系统行腹腔镜脾脏切除术12例患者的临床资料。结果:用LigaSure血管闭合系统闭合处理脾动脉、脾静脉(直径<7mm)2例,丝线结扎加LigaSure血管闭合系统闭合处理脾动脉、脾静脉10例,闭合处理胃短血管、脾结肠、脾肾和脾隔韧带12例,无中转开腹、死亡病例和并发症发生,平均手术时间97min,术中平均失血89ml,患者均于术后1d开始进食,平均住院时间8.4d。结论:在腹腔镜脾脏切除术中,利用LigaSure血管闭合系统闭合处理脾动静脉、胃短血管、脾结肠和脾隔韧带安全可靠,可明显缩短手术时间,减少术中出血。     

超声刀行开放性甲状腺手术与传统手术的对比分析

回顾性分析2009年10月-2011年10月用超声刀行开放性甲状腺手术96例（超声刀组）与同期传统手术87例（传统组）患者的临床资料,比较2组切口长度、手术时间、术中出血量、术后引流量及术后并发症情况.超声刀组的手术时间、术中出血量、切口长度、术后引流量均显著少于传统组（P＜0.01）,2组术后并发症差异无统计学意义（P＞0.05）.超声刀在开放性甲状腺手术中能显著缩短切口长度及手术时间、减少术中出血量及术后引流量,且不增加并发症,值得推广.     

LigaSure与超声刀在全腹腔镜子宫切除术中的应用

目的探讨LigaSure与超声刀在全腹腔镜子宫切除术中的应用价值。方法回顾分析2002年1月～2006年12月225例腹腔镜全子宫切除术的临床资料,其中应用LigaSure手术152例、应用超声刀手术73例。结果LigaSure组手术时间为（104.9±29.2）min,显著短于超声刀组（152.4±46.6）min（t=-9.329,P=0.000）;LigaSure组术中出血量为（32.9±14.9）ml,显著少于超声刀组（126.4±12.1）ml（t=-46.710,P=0.000）。2组均无中转开腹,无术中副损伤及术后并发症。结论采用LigaSure和超声刀行腹腔镜子宫切除术均安全、可靠。LigaSure在处理子宫血管方面更具有优势,超声刀在打开膀胱反折和离断主韧带方面效果理想。     

超声刀在开放性甲状腺手术中应用的前瞻性研究

目的：探讨超声刀在开放性甲状腺手术中应用的有效性及安全性。 方法：采用前瞻性随机对照方法,将2010年2月—2012年5月210例患者分为超声刀组与电刀组,各105例,分别采用超声刀与传统电刀手术方法行开放性甲状腺切除术,手术均由普外科甲状腺手术经验丰富同一手术团队完成。比较两组在不同手术方式中手术时间、术中出血量、术后引流量、术后并发症等指标。 结果：两组患者年龄、性别、肿块大小及疾病构成比差异无统计学意义（均P>0.05）。在相同的手术方式中,超声刀组手术时间手术、术中出血量及术后引流量（减少10~40 mL）均较传统结扎结合电刀组明显减少,组间差异均有统计学意义（P<0.05）;两组间术后并发症的差异无统计学意义（P>0.05）。 结论：超声刀集切割、止血于一体,简化手术操作过程;在开放性甲状腺手术中应用超声刀,可缩短手术时间,减少出血。     

A Comparison of the LigaSure and Harmonic Scalpel in Thyroid Surgery: A Single Institution Review

Background

During the last few years, many surgeons have begun to utilize the LigaSure device or Harmonic scalpel to perform thyroid surgery. Several papers have demonstrated the benefits of these devices compared with traditional hand-tying techniques. The purpose of this study was to examine our institution’s experience with the LigaSure device and Harmonic scalpel during thyroid surgery and to compare mean operative times and complications associated with each device.

Methods

A retrospective chart review was performed on all patients who underwent thyroid surgery using the LigaSure device or Harmonic scalpel at a single institution between December 2005 and August 2009. Charts were reviewed for patient demographics, mean operative time, length of stay, and complications, such as transient recurrent laryngeal nerve injury, hypocalcemia, and hematoma formation.

Results

A total of 231 patients were included in the study, of whom 123 underwent total thyroidectomy and 108 underwent lobectomy. There was a significant decrease in the operative time for both thyroidectomies and lobectomies when the Harmonic scalpel was utilized. In regard to complications, there was no statistically significant difference in the number of transient and permanent recurrent laryngeal nerve injuries, percentage of patients developing hypocalcemia, or rate of hematoma development.

Conclusion

In this study, there was no difference in the rate of complications between the two devices. However, the use of the Harmonic scalpel significantly decreased operative time for both thyroidectomies and thyroid lobectomies compared with the LigaSure device.     

The use of the harmonic scalpel in thyroid surgery. Our experience

The aim of this study was to evaluate the potential advantages of the use of Harmonic Scalpel in thyroidectomies in terms of operative time and complications. Between May 2007 and June 2010 1151 patients were submitted to total thyroidectomy. In 681 thyroidectomies were performed using harmonic scalpel FOCUS (group A), in 470 without it (group B). Mean operative time was 97 minutes in group A and 114 in group B with a mean difference of 17 minutes (14.9%). 554 patients in group A (81.35%) and 345 in group B (73.4%) were discharged in second postoperative day. In group A, hypoparathyroidism was present in 348 patients at discharge (48%), in 23 at 6 months (3.38%) and in 10 at 12 months (2.13%), in group B, in 255 at discharge (54.26%), in 61 at 6 months (12.98%) and in 28 at 12 months (5.96%). The major benefit of Harmonic Scalpel used during thyroidectomy is the reduction in the time of operation. All studies but one to date have reported reductions in operative time, ranging from 6 to 78 minutes with a 10% to 35% savings in operative time and this was confirmed in our study. A reduction of hypoparathyroidism, particularly transitory, and in length of hospital stay was reported in some studies and confirmed in our experience. The use of Harmonic Scalpel in thyroid surgery is safe and effective and is associated with a significant reduction in operative time, postoperative hypocalcaemia and hospital stay, without increasing complications rate.     

Use of the electrothermal vessel sealing system versus standard vessel ligation in thyroidectomy

OBJECTIVE: The electrothermal vessel sealing system (LigaSure) facilitates operative haemostasis by fusing blood vessel walls to form a collagen seal. The LigaSure is currently used in a variety of gastrointestinal, gynaecological and urological operations. We report our experience with LigaSure for thyroidectomy to test the hypothesis that it reduces operating time without increasing complications compared with standard vessel ligation. METHODS: This non-randomized, retrospective review included 234 consecutive patients who underwent thyroidectomy by one surgeon. Standard vessel ligation was used in 99 patients between 1997 and 2000, and the LigaSure was used in 135 patients between 2001 and 2003. The following data were collected: patient demographics, thyroid pathology, type of operation (total thyroidectomy vs lobectomy), operating time, complications (transient or permanent hypocalcaemia, 相似文献   

Use of a diathermy system in thyroid surgery

HYPOTHESIS: New hemostatic methods have been widely used in open and laparoscopic surgery. The LigaSure Precise diathermy system (Valleylab, Boulder, Colo) has been recently used in thyroid surgery. We hypothesized that its use could lead to reduced operative time and fewer complications compared with conventional knot tying in total or near-total thyroidectomy. DESIGN: Prospective case-controlled study. SETTING: Tertiary care private hospital. PATIENTS: Eighty patients underwent total or near-total thyroidectomy by 1 surgeon. INTERVENTIONS: Forty patients underwent thyroidectomy with the conventional knot tying technique and 40 patients with the LigaSure diathermy system. MAIN OUTCOME MEASURES: Demographics, histopathological diagnosis, operative time, intraoperative blood loss, complications, and cost, using chi2 test and Wilcoxon rank sum test. RESULTS: The study groups had similar demographic and histopathological characteristics. The mean +/- SD operative time was nonsignificantly reduced in the LigaSure group compared with the conventional knot tying group (84 +/- 6 vs 89 +/- 7 minutes, P = .60). The mean +/- SD intraoperative blood loss was less for the LigaSure group (30 +/- 5 vs 35 +/- 8 mL, P = .36). There was 1 case of transient recurrent laryngeal nerve palsy in the LigaSure group. One patient from this group and 2 patients from the other group exhibited transient hypocalcemia; permanent postoperative hypocalcemia was not encountered in either group. The cost of the LigaSure diathermy system was significantly greater than that of conventional knot tying. CONCLUSION: Use of the LigaSure in thyroid surgery did not significantly reduce operative time, blood loss, or complication rates compared with conventional knot tying, but it increased operative cost.     

钳式LigaSure和钳式超声刀在开放性甲状腺全切除术中的应用比较研究

目的比较钳式LigaSure（LSJI）和钳式超声刀（FOCUS）在开放性甲状腺全切除术中的临床应用效果。 方法回顾性分析中山大学孙逸仙纪念医院甲状腺外科2013年6月至10月行开放性甲状腺全切除术的189例患者资料,按照术中使用的辅助工具分为FOCUS辅助下手术组（F组）及LSJI辅助下手术组（L组）,比较两组患者的病史特点、切除甲状腺时间、术中、术后出血量及术后并发症的发生率。 结果L组切除甲状腺平均时间为（35.3±8.6）min,F组为（48.5±9.1）min。切除甲状腺时间长短与术中使用的辅助工具相关,两者之间的差异有统计学意义（P<0.05）;而两组患者的术中、术后出血量、术后血肿发生率、甲状旁腺功能减退发生率、喉返神经损伤性声嘶发生率等差异无统计学意义。 结论LSJI和FOCUS作为甲状腺全切除术的辅助工具均是安全、有效的,但LSJI有助于更高效完成手术。     

LigaSure versus clamp-and-tie thyroidectomy for benign nodular disease

BACKGROUND: LigaSure is an alternative bipolar diathermy system (BDS) combining vessel sealing with reduced thermal spread, which has been successfully used in many abdominal operations; however, there is a little experience in open thyroidectomy. This study compares the efficacy and the advantages of the LigaSure BDS when used for total thyroidectomy for benign thyroid disease with the conventional clamp-and-tie technique. METHODS: Between May 1998 and October 2002, 517 patients underwent total thyroidectomy for benign thyroid multinodular goiter. Among them, from May 1998 until May 2000, 247 patients (group I) were operated on with the conventional clamp-and-tie technique, whereas from May 2000 until October 2003, 270 patients (group II) underwent total thyroidectomy for benign multinodular goiter with LigaSure BDS through a 4-cm transverse suprasternal incision. Demographics, pathologic characteristics, gland mass, operative time, blood loss, and complications were assessed. RESULTS: There were no intraoperative complications. Thyroid mass was similar in both groups, but the operative time was shorter in group II than in group I (mean +/- standard deviation, 71 +/- 14 minutes vs 86 +/- 22 minutes; p < .01). Intraoperative total blood loss was similar between the two groups, but postoperative drain volume was less in group II than in group I (21 +/- 15 mL; p < .01). Major post-thyroidectomy complications (ie, laryngeal nerve palsy, hematoma, and hypocalcemia) occurred less frequently in the LigaSure group than in the clamp-and-tie group (0.7%, 0.4%, 1.1% vs 4%, 2%, 4.8%, respectively; p < .05). The mean +/- standard deviation postoperative hospital stay was significantly less for the patients in group II than for those in group I (2.3 +/- 1.7 days vs 2.8 +/- 1.3 days; p < .05). CONCLUSIONS: The use of the LigaSure vessel sealer for thyroid surgery is an effective and safe alternative that reduces the overall operative time and could be successfully applied through a narrow surgical incision.     

Clipless and sutureless laparoscopic surgery for adrenal and extra-adrenal tumors

BACKGROUND: Newer, energy-based devices like the ultrasonic coagulator (Harmonic Scalpel, Ethicon Endo-Surgery, Inc., Cincinnati, OH) and the LigaSure vessel-sealing system (Valleylab, Boulder, CO) are increasingly being used in advanced laparoscopic procedures. Use of these devices has resulted in shorter operative time, less blood loss, and lower conversion rates. We present our experience with these devices for laparoscopic removal of adrenal and extra-adrenal tumors. METHODS: Ten patients with adrenal tumors and 4 with extra-adrenal tumors were operated on laparoscopically with the ultrasonic shears and LigaSure vessel-sealing system. The entire surgery was carried out using these energy-based devices without using any clips or sutures. RESULTS: No conversions were necessary. None of the patients experienced any major intraoperative or postoperative bleeding. The mean size of the tumor was 6.2 cm (range, 3 to 8). The mean operative time was 123 minutes (range, 80 to 210), and the mean blood loss was 70 mL (range, 10 to 150). Histopathology revealed pheochromocytomas in 7 patients. CONCLUSIONS: Use of the LigaSure vessel-sealing device along with ultrasonic shears for laparoscopic removal of adrenal and extra-adrenal tumors is safe and effective.     

后腹腔镜肿瘤剜除术治疗肾错构瘤(附20例报告)

目的:探讨后腹腔镜保留肾单位手术治疗肾错构瘤的手术技巧和临床效果。方法:采用后腹腔镜技术对20例肾错构瘤患者行肿瘤剜除术。其中择期手术患者19例,因肾错构瘤破裂出血急诊手术1例。肿瘤直径1.8～8.7cm,平均4.8cm。采用单纯肾动脉阻断并以吸引器吸除肿瘤的手术方法,观察手术时间、术中出血量、术后住院天数和术中术后并发症及手术效果。结果:20例手术均获得成功,无中转开放手术。平均手术时间119min,19例择期手术患者平均出血量85ml,急诊患者未行肾动脉阻断,术中出血约为1 000ml。平均术后住院时间9.9d。1例术后出现尿瘘,经保守治疗愈合出院。其他患者无围手术期并发症。术后随访3～60个月,无肿瘤复发。结论:后腹腔镜肾错构瘤剜除术应用肾动脉热缺血阻断、介入超声、吸引器吸除肿瘤、术前放置输尿管导管、止血手段等新技术安全可行,具有创伤小、并发症少、恢复快、住院时间短等优点。     

Harmonic Scalpel versus cold knife dissection in superficial parotidectomy.

OBJECTIVES: Use of the Harmonic Scalpel has recently been described in thyroid surgery, in which it appears to result in decreased operative time and blood loss without increasing the incidence of nerve injury when compared to conventional techniques of vessel ligation and tissue division. We sought to determine whether the use of the Harmonic Scalpel in superficial parotidectomy was associated with a difference in operative time, blood loss, or facial nerve injury compared with conventional techniques. STUDY DESIGN AND SETTING: The medical records of all patients who underwent superficial parotidectomy for benign parotid pathology at the Medical College of Georgia and Veterans Affairs Hospital of Augusta, Georgia, from 1999 to 2002 were retrospectively reviewed. Patients were excluded if they had a history of a bleeding disorder, prior facial nerve weakness, prior parotid surgery, malignant pathology, or required total parotidectomy. RESULTS: Forty-two patients were eligible for inclusion. Nineteen patients underwent Harmonic Scalpel parotidectomy (HS) and 21 patients underwent conventional parotidectomy (control group). There were no significant differences between the 2 groups with respect to demographic data, pathology, or tumor size. Use of the Harmonic Scalpel was associated with a significant reduction in length of surgery (167.5 +/- 42.6 min vs. 195.5 +/- 37.4 min for controls, P = 0.03) and intraoperative blood loss (37.5 +/- 25.8 mL vs. 60.0 +/- 37.1 mL for controls, P = 0.03). There were no significant differences between the HS or control groups with respect to postoperative drain output (48.7 +/- 33.8 mL vs. 48.0 +/- 22.9 mL, respectively, P > 0.05) or facial nerve function. CONCLUSION: Use of the Harmonic Scalpel for superficial parotidectomy is safe and may result in reduced operative time and blood loss compared with conventional techniques. Significance A safe alternative to cold knife superficial parotidectomy is presented with the potential benefits of reduced operative time and blood loss demonstrated.     

Impact of Harmonic Scalpel on operative time during video-assisted thyroidectomy

BACKGROUND: Minimally invasive video-assisted thyroidectomy (MIVAT) has been practiced in our department since 1998. It has some advantages over conventional surgery in terms of postoperative pain and cosmetic result. The aim of this study was to evaluate the use of the Harmonic scalpel (HS) on the performance of this procedure. METHODS: Between October 1998 and January 2001, 116 patients underwent MIVAT. The HS was used for the last 26 operations. We compared this group of patients (HS-G) with a control group (C-G) of 26 patients who had undergone MIVAT before the introduction of the HS. The following parameters were considered: age, gender, preoperative diagnosis, size of the lesion, type of operation (lobectomy or total thyroidectomy), operative time, complication rate, and postoperative hospital stay. RESULTS: The two groups were well matched for age, gender, preoperative diagnosis, lesion size, and type of operation. The mean operative time was significantly reduced in the HS-G for both lobectomy (37.3 +/- 8.4 vs 49.4 +/- 18.0 min) and total thyroidectomy (53.8 +/- 16.3 vs 90.6 +/- 22.1 min). No differences were found for postoperative stay. One patient in the C-G experienced a transient recurrent nerve palsy. There were no other complications. CONCLUSIONS: This study showed that the utilization of the HS for MIVAT is safe and associated with a shorter operative time. A reduction of the rates for such complications such as hypoparathyroidism and recurrent nerve injuries was not possible to demonstrate in the present study. Much larger series are needed for further evaluation of this instrument.