Stability of the mandible following advancement: a comparison of three postsurgical fixation techniques

This study examines short-term stability of the mandible following mandibular advancement surgery by means of three standard techniques of postsurgical fixation. Twenty-two adult female rhesus monkeys (Macaca mulatta) underwent sagittal ramus advancement osteotomy of approximately 4 to 6 mm. Six animals had dental maxillomandibular fixation alone. Six animals had dental plus skeletal maxillomandibular fixation with circummandibular wires connected to pyriform aperture wires. Ten animals had rigid internal fixation with bicortical bone screws between the proximal and distal segments without maxillomandibular fixation. Radiographic cephalograms with the aid of tantalum bone markers and dental amalgams were analyzed during the first 6 postoperative weeks to evaluate skeletal and dental stability. Rigid internal fixation and the use of dental plus skeletal maxillomandibular fixation were both equally effective in the prevention of postsurgical relapse. However, in the animals in which only dental maxillomandibular fixation was used, statistically significant changes (relapse) occurred when compared with either of the other groups.     

Stability after surgical-orthodontic correction of skeletal Class III malocclusion. 2. Maxillary advancement.

Nearly half the patients with skeletal Class III malocclusion have maxillary deficiency as the major component of their problem, and modern surgical techniques allow maxillary osteotomy to correct the deformity. Changes at surgery and postsurgically were studied in 49 patients who underwent isolated surgical maxillary advancement. Thirty-one had wire osteosynthesis and maxillomandibular fixation, and 18 had rigid fixation with bone plates. In nearly half the patients, the maxilla was moved down as well as forward, indicating that the patient had both vertical and anteroposterior deficiency. In the anteroposterior plane, 80% of the patients had excellent stability at 1 year, while 20% had 2 to 4 mm of posterior movement of anterior maxillary landmarks. There was no difference in anteroposterior stability between wire/maxillomandibular fixation and rigid internal fixation groups. When the maxilla was moved down as well as forward, there was a strong tendency for relapse upward in both fixation groups. As a result, the chin frequently became more prominent from immediate postsurgery to 1-year followup, as upward movement of the maxilla allowed the mandible to rotate upward and forward.     

Stability of the mandible after advancement and use of dental plus skeletal maxillomandibular fixation: an experimental investigation in Macaca mulatta

This study examined short-term stability of the mandible following advancement surgery and the use of skeletal suspension wires plus dental maxillomandibular fixation. Twenty-four adult female Macaca mulatta underwent bilateral sagittal ramus osteotomy and advancement of approximately 6 mm. All animals had dental maxillomandibular fixation secured by bonding the upper and lower teeth together with an orthodontic composite resin. In half of the animals, the use of circummandibular wires connected to pyriform aperture wires were additionally applied. Tantalum bone markers were placed and cephalograms analyzed during the first six postoperative weeks to evaluate skeletal stability. A statistically significant mean horizontal relapse at the mandibular symphysis occurred in the group without the skeletal wires, whereas no relapse occurred in the group with the skeletal wires. A significant difference in the vertical displacement of the anterior mandible occurred, with an inferior movement of the symphysis in the group without skeletal wires, and a superior movement of the symphysis in the group with skeletal wires. The results of this study indicate that the use of skeletal suspension wires is advantageous in the prevention of horizontal and vertical skeletal relapse.     

Stability of skeletal class III malocclusion after combined maxillary and mandibular procedures: rigid internal fixation versus wire osteosynthesis of the mandible.

PURPOSE: The aim of this study was to evaluate skeletal stability after double-jaw surgery for correction of skeletal Class III malocclusion to assess whether there were any differences between wire and rigid fixation of the mandible. PATIENTS AND METHODS: Thirty-seven Class III patients had Le Fort I osteotomy stabilized with plate and screws for maxillary advancement. Bilateral sagittal split osteotomy for mandibular setback was stabilized with wire osteosynthesis and maxillomandibular fixation for 6 weeks in 20 patients (group 1) and with rigid internal fixation in 17 patients (group 2). Lateral cephalograms were taken before surgery, immediately after surgery, 8 weeks after surgery, and 1 year after surgery. RESULTS: Before surgery, both groups were balanced with respect to linear and angular measurements of craniofacial morphology. One year after surgery, maxillary sagittal stability was excellent in both groups, and bilateral sagittal split osteotomy accounted for most of the total horizontal relapse observed. In group 1, significant correlations were found between maxillary advancement and relapse at the posterior maxilla and between mandibular setback and postoperative counterclockwise rotation of the ramus and mandibular relapse. In group 2, significant correlations were found between mandibular setback and intraoperative clockwise rotation of the ramus and between mandibular setback and postoperative counterclockwise rotation of the ramus and mandibular relapse. No significant differences in postoperative skeletal and dental stability between groups were observed except for maxillary posterior vertical position. CONCLUSIONS: Surgical correction of Class III malocclusion after combined maxillary and mandibular procedures appears to be a fairly stable procedure independent of the type of fixation used to stabilize the mandible.     

Stability after surgical-orthodontic correction of skeletal Class III malocclusion. I. Mandibular setback

Postsurgical stability of mandibular setback to correct mandibular prognathism was compared for three approaches: transoral vertical ramus osteotomy, bilateral sagittal split osteotomy with wire osteosynthesis and maxillomandibular fixation, and bilateral sagittal split osteotomy with rigid internal fixation via bone screws. In the transoral vertical ramus osteotomy group, the mean postsurgical change in chin position was almost zero, but nearly 50% of the patients did have clinically significant changes in chin position; two thirds of these movements were posterior and one third anterior. In the bilateral sagittal split osteotomy groups, the chin either stayed in its immediately postsurgical position or moved anteriorly. In one fourth of the patients who received maxillomandibular fixation and in nearly half of the patients who received rigid internal fixation, the chin moved forward more than 4 mm.     

Intraoral maxillary quadrangular Le Fort II osteotomy: a long-term follow-up study.

PURPOSE: This study evaluated the clinical outcome and skeletal stability of the intraoral maxillary quadrangular Le Fort II osteotomy (IQLO) with wire or rigid internal fixation following horizontal maxillary advancement. PATIENTS AND METHODS: All 21 patients who had undergone the IQLO were analyzed for operation time, blood loss, length of hospitalization, intraoperative and postoperative complications, and radiographic abnormalities. Lateral cephalometric radiographs were taken preoperatively (T1), postoperatively (T2) and late postoperatively (T3) to analyze skeletal movement. Two maxillary landmarks (posterior nasal spine [PNS] and A point) and 2 dental landmarks (the distobuccal cusp tip of the maxillary left second molar [2M] and the maxillary incisal tip [CI]) were used to determine horizontal and vertical changes for each time period. Student t test was used to evaluate early postoperative changes and late postoperative stability. In addition, 21 patients completed a questionnaire at the most recent follow-up visit regarding personal intentions, perceived outcome, and overall satisfaction. RESULTS: Twenty-one patients (9 females, 12 males) with an average age of 20.3 years diagnosed with horizontal maxillary-zygomatic deficiency underwent IQLO by 1 surgeon with an average follow-up of 6.3 years. Nine patients received mini-plate osseous segment fixation and 12 patients received wire osseous segment fixation. The mean time from surgery to the first postoperative radiograph (T2) was 4.4 weeks (range 1.0 to 6.7 weeks) and the mean time from surgery to the late postoperative radiograph (T3) was 6.2 years (range, 7.9 to 176.3 months). Statistical analysis of cephalometric landmarks revealed the following significant late postsurgical movements (T3-T2) for wire fixation: PNS moved 1.0 mm inferiorly (SD, 1.2), and 2M moved 1.5 mm inferiorly (SD, 2.2). The remaining cephalometric landmarks for rigid and wire fixation showed no statistically significant late postsurgical movement. Clinical outcome analysis revealed few complications, low surgical and postsurgical morbidity, and excellent patient satisfaction. CONCLUSION: The IQLO is a predictable procedure that exhibits long-term skeletal stability. Long-term retrospective review revealed low postsurgical morbidity and high patient satisfaction.     

Mobility of the mandible following advancement and maxillomandibular or rigid internal fixation: an experimental investigation in Macaca mulatta

This study examined the postsurgical range of mandibular motion following sagittal advancement osteotomy in Macaca mulatta when either maxillomandibular or rigid osseous fixation were used. Seventeen adult female Macaca mulatta underwent sagittal advancement osteotomy of approximately 4 to 6 mm. Six had 6 weeks of maxillomandibular fixation and eleven had rigid osseous fixation with no maxillomandibular fixation. Mandibular range of motion was measured by the change in the angle of the posterior aspect of the mandibular ramus from a closed-mouth and an open-mouth cephalogram. Parametric tests were used to statistically analyze the results. The results of this investigation showed that the animals who did not undergo maxillomandibular fixation maintained a greater range of motion in the early postsurgical period and obtained preoperative mobility by 12 weeks postsurgery. The animals who underwent six weeks of maxillomandibular fixation showed statistically significant decreases in range of motion when compared to the rigid fixation group at each period of time postsurgery, with significant reductions from preoperative values at 12 weeks postsurgery.     

Stability of simultaneous maxillary and mandibular osteotomy for treatment of class III malocclusion: an analysis of three-dimensional cephalograms.

PURPOSE: The current investigation was undertaken to study the three-dimensional (3-D) stability of simultaneous maxillary advancement and mandibular setback using rigid fixation. The study also aimed to analyse the factors involved in postsurgical relapse by evaluation of changes in various parameters. PATIENTS: Twenty-five cases were evaluated of simultaneous Le Fort I maxillary advancement and mandibular setback using rigid fixation. METHODS: Preoperative, immediate and 6-month postoperative skeletal and dental changes were analysed using 3-D cephalograms obtained from biplanar stereoradiography. Maxillary fixation screws were used as landmarks to evaluate postoperative stability. RESULTS: The mean maxillary advancement was 3.7 mm. Relapse in the sagittal, vertical, and transverse planes was not detectable in the maxilla (p > 0.05). However, for an average mandibular setback of 5.7 mm, mean mandibular relapse was 1.1 mm or 19.3% anteriorly (p < 0.05). Surgical or postsurgical skeletal changes in the maxilla had no detectable influence on mandibular relapse (p > 0.05). Vertical alterations of the facial skeleton achieved surgically predicted the mandibular relapse (R2 = 0.27, p < 0.05). CONCLUSION: Maxillary advancement and vertical changes of +/- 2 mm did not influence the postoperative stability of the mandible. Relapse of the mandible seems to be influenced mainly by the amount and direction of the surgical alteration of mandibular position.     

Stability of skeletal Class III malocclusion after combined maxillary and mandibular procedures: titanium versus resorbable plates and screws for maxillary fixation.

PURPOSE: The aim of this study was to evaluate skeletal stability after double jaw surgery for correction of skeletal Class III malocclusion to assess if there were any differences between resorbable plate and screws and titanium rigid fixation of the maxilla. PATIENTS AND METHODS: Twenty-two Class III patients had bilateral sagittal split osteotomy for mandibular setback stabilized with rigid internal fixation. Low level Le Fort I osteotomy for maxillary advancement was stabilized with conventional titanium plate and screws in 12 patients (group 1) and with resorbable plate and screws in 10 patients (group 2). Lateral cephalograms were taken before surgery, immediately postoperatively, 8 weeks after surgery, and 1 year postoperatively. RESULTS: Before surgery both groups were balanced with respect to linear and angular measurements of craniofacial morphology. One year after surgery, maxillary stability was excellent in both groups. In group 1 no significant correlations were found between maxillary advancement and relapse. In group 2, significant correlations were found between maxillary advancement and relapse at A point and posterior nasal spine. No significant differences in postoperative skeletal and dental stability between groups were observed. CONCLUSION: Surgical correction of Class III malocclusion after combined maxillary and mandibular procedures appears to be a fairly stable procedure for maxillary advancements up to 5 mm independently from the type of fixation used to stabilize the maxilla. Resorbable devices should be used with caution for bony movements of greater magnitude until their usefulness is evaluated in studies with large maxillary advancements.     

A comparative study of skeletal and dental stability between rigid and wire fixation for mandibular advancement

This study examined the skeletal and dental stability after mandibular advancement surgery with rigid or wire fixation for up to 2 years after the surgery. Subjects for this multisite, prospective, randomized, clinical trial were assigned to receive rigid (n = 64) or wire (n = 63) fixation. The rigid cases received three 2-mm bicortical position screws bilaterally and elastics; the wire fixation subjects received inferior border wires and 6 weeks of skeletal maxillomandibular fixation with 24-gauge wires. Cephalometric films were obtained before surgery, and at 1 week, 8 weeks, 6 months, 1 year, and 2 years after surgery. Skeletal and dental changes were analyzed using the Johnston's analysis. Before surgery both groups were balanced with respect to linear and angular measurements of craniofacial morphology. Mean anterior advancement of the mandibular symphasis was 5.5 mm (SD, 3.2) in the rigid group and 5.6 mm (SD, 3.0) in the wire group. Two years after surgery, mandibular symphasis was unchanged in the rigid group, whereas the wire group had 26% of sagittal relapse. Dental compensation occurred to maintain the corrected occlusion, with the mandibular incisor moving forward in the wire group and posteriorly in the rigid group. However, at 2 years after surgery, when most subjects were without braces, the overjet and molar discrepancy had relapsed similarly in both groups.     

骨性Ⅲ类与Ⅰ类错患者基骨及牙弓宽度的比较研究

目的：评价骨性Ⅲ类错合与骨性I类个别正常合上下颌第一磨牙区基骨及牙弓宽度差异。方法：选取骨性Ⅲ类错合患者与骨性I类个别正常合样本各30例。测量CBCT数据中上颌骨颧弓点和下颌第一磨牙阻抗中心对应的颊侧骨皮质点间的距离作为基骨宽度；测量模型上下颌第一磨牙中央窝之间的距离作为牙弓宽度。使用SPSS 22.0独立样本t检验。结果：上颌基骨宽度Ⅲ类组（63.96±3.78mm）小于I类组（65.67±2.76mm）；下颌基骨宽度Ⅲ类组（62.26±3.12mm）大于I类组（60.29±3.15mm）；基骨宽度差为Ⅲ类组（2.31±2.41mm）小于I类组（5.38±1.24mm）。差异均有统计学意义（P<0.05）。Ⅲ类组与I类组上下颌牙弓宽度均无组间差异（P>0.05）。结论：骨性Ⅲ类患者存在上下颌基骨横向发育不调及上下颌磨牙的颊舌向代偿。     

Relapse following mandibular advancement with dental plus skeletal maxillomandibular fixation

This study examines the short-term stability of the mandible following mandibular advancement surgery in which skeletal suspension wires were used in addition to dental maxillomandibular fixation. Twenty adults underwent sagittal ramus osteotomies. No concomitant surgical procedures were performed. Maxillomandibular fixation consisted of wiring between the upper and lower orthodontic brackets and circummandibular wires connected to the piriform aperture or anterior nasal spine wires for eight weeks. Cephalograms were analyzed during this period to evaluate skeletal stability. A statistically insignificant mean horizontal relapse of 8.9% was found at pogonion during the period of fixation. Significant vertical intrusion of the anterior mandible occurred, however, with a mean superior movement of pogonion of 0.83 mm (P less than or equal to 0.05). Dental changes noted were uprighting of the maxillary incisors and flaring of the mandibular incisors. In comparison with the results of other studies in which dental maxillomandibular fixation was used alone, the results of this study indicate that the use of skeletal suspension wires is advantageous in the prevention of horizontal skeletal relapse.     

Rigid versus wire fixation for mandibular advancement: Skeletal and dental changes after 5 years

The bilateral sagittal split osteotomy (BSSO) is the most common surgical procedure for the correction of mandibular retrognathism. Commonly, the proximal and distal segments are fixated together with either wire or rigid screws or plates. The purpose of this study was to compare long-term (5 years) skeletal and dental changes between wire and rigid fixation after BSSO. In this multisite, prospective, randomized clinical trial, the rigid fixation group received three 2-mm bicortical position screws, and the wire fixation group received inferior border wires and 6 weeks of skeletal maxillomandibular fixation with 24-gauge wires. Cephalometric films were obtained 2 weeks before surgery and at 1 week, 8 weeks, 6 months, 1 year, 2 years, and 5 years after surgery. Linear cephalometric changes were referenced to a cranial base coordinate system. Before surgery, both groups were comparable with respect to linear and angular measurements of craniofacial morphology. Both groups underwent similar surgical changes. Skeletal and dental movements occurred in both groups throughout the study period. Five years after surgery, the wire group had 2.2 mm (42%) of sagittal skeletal relapse, while the rigid group remained unchanged from immediately postsurgery. Surprisingly, at 5 years, both groups had similar changes in overbite and overjet. This was attributed to dental changes in the maxillary and mandibular incisors. Although rigid fixation is more stable than wire fixation for maintaining the skeletal advancement after a BSSO, the incisor changes made the resultant occlusions of the 2 groups indistinguishable.     

A comparison of stimulated bite force after mandibular advancement using rigid and nonrigid fixation

This study evaluated maximum stimulated molar bite force following advancement of the mandible in 17 adult Macaca mulatta using rigid and nonrigid fixation techniques. Cephalometric analysis was also performed to determine the amount of proximal segment rotation. Analysis of the bite force showed the animals whose mandibles were advanced using rigid fixation to have significantly greater bite force at six weeks postsurgery when compared to those animals who underwent mandibular advancement and six weeks of maxillomandibular fixation. By the ninth postoperative week, there was no longer any significant difference between the two groups, indicating a rapid recovery of muscle function in the animals whose mandibles were immobilized following advancement. Both groups, however, had significant decreases in bite force at 12 weeks postsurgery when compared to preoperative values. Neither group had a significant amount of proximal segment rotation from the surgery.     

LeFort I soft tissue distraction: a hybrid technique

Distraction osteogenesis of the craniofacial skeleton has greatly enhanced traditional osteotomies and bone grafting techniques. The obvious drawbacks to an external distraction device are visibility and awkwardness. A hybrid technique of maxillary distraction for soft tissue expansion and formation of regenerate, combined with rigid internal fixation, is proposed. This technique permits maxillary advancement that may be unattainable by traditional methods and obviates the extended use of external hardware during latency and consolidation of the regenerate. It also allows for optimization of the dental occlusion. The study group was composed of five patients with severe skeletal class III malocclusion who had combined maxillary distraction followed by rigid internal fixation. The average age at the time of LeFort osteotomy was 17 years, with a range of 13 to 19 years. The latency period ranged from 1 to 5 days, and distraction was done at the rate of 1 mm/d in all patients. After the proposed advancement was attained, all patients had reoperation, consisting of distractor removal, optimized interdental relationships with intermaxillary fixation, and placement of rigid internal fixation. The average anterior-posterior maxillary advancement was 11.6 mm, with a range of 10 to 13 mm. Lateral cephalograms and clinical examination showed no relapse at an average follow-up of 25 months, with a range of 5 to 40 months.     

Stability following combined maxillary and mandibular osteotomies treated with rigid internal fixation

Skeletal stability was examined in 16 patients following combined maxillary and mandibular osteotomies using rigid internal fixation. Postoperative changes (T2 to T3) were generally less than 1.0 mm for linear measurements and less than 2.0 degrees for angular measurements. The removal of maxillomandibular fixation (MMF) splints accounted for 85% to 95% of the counterclockwise rotation in the proximal and distal mandibular segments from T2 to T3. Maxillary inferior repositioning and large mandibular advancements exhibited the greatest tendency for relapse; however, the changes were less than with comparable procedures using nonrigid methods for stabilization. Except for large mandibular advancements, relapse was essentially unrelated to the magnitude of the surgical repositioning. Although the use of skeletal, maxillomandibular, and transosseous wire fixation have traditionally provided satisfactory clinical results, the use of rigid internal fixation in combined osteotomy procedures provides better stabilization of dentosseous segments when compared with these nonrigid methods, and may be particularly indicated in complex surgical procedures.     

Stability of the Le Fort I osteotomy with anterior internal fixation alone: a case series.

PURPOSE: The purpose of this case series was to evaluate the late postsurgical stability of the Le Fort I osteotomy with anterior internal fixation alone and no posterior zygomaticomaxillary buttress internal fixation. PATIENTS AND METHODS: Sixty patients with maxillary vertical hyperplasia and mandibular retrognathia underwent a 1-piece Le Fort I osteotomy of the maxilla with superior repositioning and advancement or setback. A bilateral sagittal split ramus osteotomy for mandibular advancement was also performed in 22 patients. Stabilization of each maxillary osteotomy was achieved using transosseous stainless steel wires and/or 3-hole titanium miniplates in the piriform aperture region bilaterally, with no zygomaticomaxillary buttress internal fixation. (Twelve of the 60 identified patients were available for a late postoperative radiographic evaluation.) Lateral cephalometric radiographs were taken preoperatively (T1), early postoperatively (T2), and late postoperatively (T3) to analyze skeletal movement. RESULTS: These 12 patients (5 male, 7 female) had a mean age of 24.5 years at surgery. Mean time from surgery to T2 was 41.2 days; mean time from surgery to T3 was 14.8 months. One patient received anterior wire osteosynthesis fixation, while 11 patients received both anterior titanium miniplate internal skeletal fixation and anterior wire osteosynthesis fixation. Six patients underwent Le Fort I osteotomy with genioplasty, 1 patient underwent Le Fort I osteotomy with bilateral sagittal split ramus osteotomy, and 5 patients underwent Le Fort I osteotomy with bilateral sagittal split ramus osteotomy and genioplasty. These 12 patients all underwent maxillary superior repositioning with either advancement (11 patients) or setback (1 patient). Statistically significant surgical (T2-T1) changes were found in all variables measured. In late postsurgical measurements (T3-T2), all landmarks in the horizontal and vertical plane showed statistically significant skeletal stability. CONCLUSION: This case series suggests that anterior internal fixation alone in cases of 1-piece Le Fort I maxillary superior repositioning with advancement has good late postoperative skeletal stability.     

A comparative study of stability after mandibular advancement surgery

The postsurgical stability of two groups of patients treated with different fixation techniques after mandibular advancement was evaluated retrospectively. Sixteen patients (group 1) underwent rigid osseous fixation, and another group of 16 patients (group 2) underwent intraosseous wiring fixation. Our findings suggested that skeletal and dental changes occurred in both groups as a result of adaptation to the altered functional equilibrium. Relapse resulting in a percentage loss of the initial advancement occurred primarily 6 to 8 weeks postsurgically. No statistically significant difference was found to exist in the short-term and long-term rates between the two groups. For the population studied, relative stability after mandibular advancement surgery was affected more by individual variability than by the fixation technique.     

Stability of midface augmentation: an experimental study of musculoskeletal interaction and fixation methods

This study examined stability of vertical midface augmentation when different methods to alleviate potentially distracting muscles were used. Eighteen adult monkeys underwent Le Fort I osteotomy with interpositional bone grafts. One group had wire fixation of the maxilla and bone graft. A second group underwent a similar procedure with the addition of myotomies of the masseter and temporalis muscles. A third group wore a bite-opening appliance before downgrafting. A fourth group underwent downgrafting with rigid internal fixation. Serial cephalograms with the aid of bone markers were used to assess postsurgical change. The results showed that the animals who underwent rigid fixation had the most stable results, followed by the myotomy and bite-opening appliance groups. The animals who underwent wire fixation with no supplemental procedures had gross relapse, resulting in an average retention of only 15% of the surgical change by 12 weeks.     

Stability of the Le Fort I osteotomy for maxillary advancement using rigid fixation and porous block hydroxyapatite grafting

PURPOSE: The purpose of this study was to evaluate the stability of maxillary advancement using bone plates for skeletal stabilization and porous block hydroxyapatite (PBHA) as a bone graft substitute for interpositional grafting. PATIENTS AND METHODS: The records of 78 patients (55 female, 23 male) with a diagnosis of anteroposterior maxillary hypoplasia were retrospectively evaluated. All patients underwent greater than 5 mm Le Fort I maxillary advancement with rigid fixation and PBHA interpositional grafting. The study sample was divided into 3 groups on the basis of the concurrent superior or inferior positioning of the maxillary incisors. Presurgery (T1), immediately postsurgery (T2), and longest follow-up (T3) lateral cephalometric tracings were superimposed to analyze for horizontal and vertical changes at the following landmarks: (1) point A, (2) incisal edge of the maxillary incisor, and (3) mesial cusp tip of maxillary first molar. RESULTS: The maxilla was inferiorly repositioned in 27 patients, superiorly repositioned in 21 patients, and advanced horizontally without a significant vertical change in 30 patients. All groups showed 0.5 mm or less horizontal and vertical relapse. There was no statistically significant difference between the 3 groups. CONCLUSIONS: Maxillary advancement with Le Fort 1 osteotomies by using rigid fixation and interpositional PBHA grafting is a stable and predictable procedure regardless of the direction of vertical maxillary movement.