动态轮廓眼压计与压平眼压计的比较

目的:评价和比较动态轮廓眼压计和Goldmann压平眼压计测得的LASIK手术后眼压值。方法:接受准分子激光原位角膜磨镶术(LASIK)的近视患者34例68眼,分别于术前和术后3mo使用动态轮廓眼压计(Pascal dynamic contour tonometer,PDCT)和Goldmann压平眼压计(the Goldmann applanation tonometer,GAT)进行眼压测量。比较手术前后两种测量方法测得的眼压值的差异。多元线性相关分析研究GAT,PDCT测量值和角膜曲率及角膜中央厚度(CCT)之间的相关性。结果:LASIK手术后GAT测量值较术前低,而PDCT值和术前比较差异则无统计学意义。角膜曲率、CCT和GAT读数呈线性相关,而与PDCT读数无关。结论:GAT测量得到的眼压低于实际值。PDCT测眼压不受角膜曲率和中央角膜厚度影响。     

动态轮廓眼压计监测LASIK手术前后眼压变化

目的比较动态轮廓眼压计(DCT)、Goldmann压平式眼压计(GAT)及非接触式眼压计(NCT)测量接受准分子激光原位角膜磨镶术(LASIK)患者眼压值的差异。设计前瞻性临床试验研究。研究对象接受LASIK治疗的近视患者70例(140眼)。方法对上述患者于术前、术后1周,1、6个月用三种不同眼压计分别测量眼压,比较各时间点、各种眼压计之间的差异。同时记录手术前、后中央角膜厚度,取其两者差为角膜切削深度的值。主要指标眼压值(IOP)和角膜切削深度。结果术后1周,1、6个月DCT测量值(16.74±1.96mmHg、16.67±1.90mmHg、16.42±2.12mmHg)与其术前值(17.36±2.32mmHg)比较差异无统计学意义(F=1.346,P=0.06)。术后GAT和NCT测量值均呈下降趋势,与术前测量值比较差异有统计学意义(GAT:F=101.217,P=0.000;NCT:F=171.466,P=0.000),并且下降值与角膜切削深度成正相关关系(GAT:r=0.86,P=0.000;NCT:r=0.87,P=0.000),但术后三个时间段测量值比较差异无统计学意义(GAT术后三个时间点q值为0.216、0.677、0.461,P值分别为0.461、0.097、0.117;NCT术后三个时间点q值为0.215、0.585、0.370,P值分别为0.436、0.436、0.100)。结论LASIK术后GAT和NCT测量值明显下降,而DCT测量值无显著变化,其测量值较前两者更为可靠。(眼科,2007,16:344-347)     

LASIK对非接触型眼压计测量眼压的影响

目的：分析准分子激光原位角膜磨镶术（ｌａｓｅｒ ｉｎ ｓｉｔｕ ｋｅｒａｔｏｍｉｌｅｕｓｉｓ,ＬＡＳＩＫ）治疗近视眼术后眼压的影响因素。方法：采用ＬＡＳＩＫ治疗２１４只近视眼。用非接触式眼压计测量术前、术后的眼压。对眼压与术前、术后各因素进行相关分析和多元逐步回归分析。结果：ＬＡＳＩＫ术后１月的眼压明显低于术前,差异具有显著性意义（ｓｔｕｄｅｎｔ ｔ检验,Ｐ〈０．０００１）。ＬＳＡＩＫ术后眼压的降     

轮廓动态眼压计测量准分子激光原位角膜磨镶术后眼压

目的通过与Goldmann眼压计(goldmann appla-nation tonometer,GAT)的比较,评价轮廓动态眼压计(dynamiccontour tonometer,DCT)在准分子激光原位角膜磨镶术(laser insitu keratomileusis,LASIK)前和术后眼压测量中的应用价值。方法在术前以及术后第1周和第4周,分别用GAT和DCT测量30例60眼的眼压,对所得结果采用SPSS 11.5统计分析软件进行统计学处理。结果中央角膜厚度(centralcorneal thickness,CCT)和GAT读数相关,而与DCT读数无关。术前眼压和术后第1周、第4周的眼压比较,GAT读数分别下降(5.00±1.12)mmHg和(5.45±1.13)mmHg,DCT则无显著性差异。结论LASIK导致的CCT变化可影响GAT测量结果的准确性,但对DCT无影响,因此,DCT更适用于正常眼以及曾接受LASIK手术眼的眼压测量。     

动态轮廓眼压计与非接触眼压计的比较

目的比较动态轮廓眼压计（DCT）与非接触眼压计（NCT）测量眼压的差异,并探讨中央角膜厚度（CCT）对这两种测量方法的影响。方法对75例拟接受近视手术的患者进行角膜厚度测量后,对所有眼分别用DCT和NCT进行眼内压（IOP）的测量,并比较中央角膜厚度与两种眼压计读数的关系。对所有数据进行t检验和相关分析。结果NCT和DCT测得的眼压值具有显著性差异（t=9．2932,P〈0．01）。NCT测量值与CCT呈正相关,相关系数r=0．3482（P〈0．01）。DCT测量值与CCT无相关性,相关系数r=0．0635,P〉0．05）。结论NCT和DCT测量眼压值有差异,DCT测量值大于NCT,CCT对NCT的影响大于DCT。     

Pascal动态轮廓眼压计在角膜屈光手术前后的应用

目的 探讨Pascal动态轮廓眼压计(dynamic contour tonometer,DCT)在角膜屈光手术前后的应用.方法 随机收集我院2009年1月至6月拟接受角膜屈光手术的屈光不正患者127例(254眼),其中男51例(102眼),女76例(152眼);年龄18～47岁,平均(22.48±3.57)岁.中央角膜厚度(central corneal thickness,CCT)为450～600 μm,平均等效球镜度数为-0.75～10.00 D.术前及术后1个月分别采用DCT和非接触式眼压计(non-contact tonometer,NCT)测量眼压,角膜超声测厚仪测量CCT,并分析眼压与CCT变化的关系.结果 术前:450 μmm550 μm时,NCT测得眼压平均值分别为(11.51±3.25)mmHg(1kPa=7.5 mmHg)、(17.58±2.97)彻Hg、(19.74±3.12)nHg,DCT测得眼压平均值分别为(16.89±2.56)mmHg、(17.33±3.32)mmHg、(17.58±2.74)mmHg,当450 μm550 μm时,DCT与NCT测得的眼压平均值比较,差异均有统计学意义(均为PO.05);术后1个月:当△CCT≤50 μm、50μm<△ccT≤100μm和△cCT>looμm时,NCT测得眼压较术前分别下降(1.46±0.81)mmHg、(3.87±1.21)mmHg、(4.19±2.68)mmHg,与术前相比差异均有统计学意义(P<0.05、P0.05).结论 DCT受角膜厚度影响较小,是角膜屈光手术前后眼压测量的一种好方法,尤其对于手术前眼压偏高的患者意义更大.     

轮廓动态眼压计在LASEK手术中应用的临床研究

目的:丝裂霉素C(mitomycin C,MMC)在LASEK术中应用对眼压的影响及轮廓动态眼压计在LASEK术中的应用。方法:在术前和术后1,4,12wk,分别采用轮廓动态眼压计(dynamic contour tonometer,DCT)测量接受LASEK治疗的对照组和MMC组近视患者各150眼的眼内压。结果:术前MMC组和对照组DCT眼压值分别为17.17±2.35,18.12±2.41mmHg。术后1,4,12wkMMC组和对照组DCT眼压值分别为17.09±2.72,17.24±2.39,17.12±2.67,17.52±2.47,18.01±2.69,17.66±2.54mmHg。手术前、后眼压差异无统计学意义。对照组和MMC组术前和术后1,4,12wkDCT眼压值,差异均无统计学意义。结论:DCT测量眼压可能更适合于曾经接受角膜屈光手术眼的眼压测量。通过DCT监测手术前、后眼压,丝裂霉素C对LASEK术后眼压无明显影响。     

Diaton眼压计与非接触式眼压计测量眼压的比较

目的比较Diaton眼压计（DT）与非接触式眼压计（NCT）测量眼压的差异。方法分别使用DT和NCT测量患者眼压,对测量值进行统计学分析,多元相关分析研究眼压测量值与年龄、角膜曲率、等效球镜度、中央角膜厚度之间的相关性。结果 DT与NCT的平均眼压测量值分别为（13.81±3.27）mmHg和（15.80±3.48）mmHg,差异有统计学意义（P〈0.05）,二者测量值的相关系数r=0.438,P〈0.05,两种眼压计的测量差值随中央角膜厚度增加而升高;将所有患者依照中央角膜厚度分为3组,NCT测量值在3组间有显著差异,而NCT测量值在3组间无差异;NCT测量值与年龄和中央角膜厚度呈正相关,而DT测量值与年龄、角膜曲率、等效球镜度、中央角膜厚度均不相关。结论 Diaton眼压计测量值不受年龄和中央角膜厚度影响,与非接触式眼压计测量值呈正相关,可应用于临床普查和诊断。     

动态轮廓眼压计和非接触眼压计测量值的比较及屈光手术对其影响

目的 比较动态轮廓眼压计(DCT)和非接触眼压计(NCT)在不同屈光度患者中测量值的差异,并探讨屈光手术对DCT和NCT测量值的影响.方法 226眼按不同屈光度分3组:轻度组31眼(-1.25D～-3.00D),中度组135眼(-3.12D～- 6.00D),高度组60眼(-6.12D～- 10.625D),各组分别用NCT和DCT测量眼压,并比较不同屈光度与两种眼压计读数的差异关系.结果 屈光手术前总NCT值与屈光度无相关关系(r=0.033,P=0.626).通过控制屈光度分级的影响进行偏相关分析,DCT与屈光度的相关系数为(r=0.079,P=0.240),且无统计学意义.术前轻度组NCT和DCT测量值差异无统计学意义(t=-1.091,P=0.284);中度组和高度组的NCT和DCT值有统计学意义(t=-2.687,P=0.008;t=-3.791,P=0.000).术后各组比较:NCT和DCT测量值均有统计学意义(t=-14.493,P=0.000;t=-28.505,P=0.000;t=-24.557,P=0.000).结论 DCT测量眼压结果 不受角膜厚度、角膜曲率及眼轴长度的影响,DCT值与患眼的屈光度也无相关性,更适应于角膜屈光手术后患眼眼压的测量和评估,但对高度近视眼手术后仍应警惕眼压被低估的可能.     

动态轮廓眼压计与Goldmann压平眼压计的临床应用比较

目的了解动态轮廓眼压计的临床实用性。方法67例患者134眼随即先后用动态轮廓眼压计与Goldmann压平眼压计进行眼压测量,比较两种眼压计测量值的差异。结果134眼中,用Goldmann压平眼压计测量的眼压平均值为(15.82±-4.88)mmHg,用动态轮廓眼压计测量的眼压平均值为(14.5±-4.33)mmHg,;两者无明显差异。但73%的患者的动态轮廓眼压计的眼压值高于Goldmann压平眼压计的测量值。两者的相关性为0.83。结论动态轮廓眼压计可以较好的反映患者的眼压,操作简便,值得推广应用。     

The applicability of correction factor for corneal thickness on non-contact tonometer measured intraocular pressure in LASIK treated eyes

Purpose

To determine the applicability of central corneal thickness (CCT) based correction factor for non-contact tonometer (NCT) measured intraocular pressure (IOP) readings.

Method

A prospective, non-randomized study involved 346 eyes of 173 consecutive patients with age ⩾21 years undergoing laser-assisted in situ keratomileusis (LASIK) for myopia and/or myopic astigmatism. The CCT and IOP were measured before and after the LASIK procedure. The IOP pre and post-LASIK was compared after applying the correction factor for CCT. Patients not completing the 3 month postoperative follow-up were excluded.

Results

The median spherical equivalent before undergoing LASIK was −4.25D (inter-quartile range, −3.25D). The mean preoperative CCT was 536.82 ± 33.71 μm which reduced to 477.55 ± 39.3 μm (p < 0.01) post-LASIK. The mean IOP reduced from a preoperative value of 14.6 ± 2.32 mmHg to 10.64 ± 2.45 mmHg postoperatively (p < 0.01). On applying correction for the corneal thickness, the pre and postoperative IOP was 15.14 ± 2.8 mmHg and 15.37 ± 2.65 mmHg (p = 0.06) respectively with a strong positive correlation (r = 0.7, p < 0.01). Three hundred eyes (86.7%) had an absolute difference in IOP of less than 3.0 mmHg post-CCT correction which is within the retest variability of NCT. Only 46 eyes (13.3%) had an absolute difference of more than 3.0 mmHg.

Conclusion

The modified Ehler’s correction algorithm used in this study can be effectively applied in the normal IOP range in a majority of patients.     

动态眼压测量计与压平式眼压计测量LASIK手术前后眼压分析

目的探讨LASIK手术前后眼压的变化规律。方法用三种不同仪器对42人84眼手术后的眼压、角膜厚度进行测量,比较手术前后眼压值及其与中央角膜厚度的关系。结果术后,电子压力感受器测得的眼压呈先升高后下降的趋势,压平式眼压计所测的眼压值较术前接近或下降,且非接触式眼压计组较Goldmann眼压计组下降更明显,中央角膜厚度与电子压力感受器原理的眼压计之间无明显相关,而与两个基于压平原理的眼压计所测值之间有不同程度的关联。结论术后角膜形状的改变对压平式眼压计的结果影响较大,而基于电子压力感受器原理的眼压计基本可以避开上述影响,激素对术后病人眼压影响较普遍,有必要对压平眼压计的结果进行进一步修正,尤其对非接触式眼压计的结果需要加以进一步的考虑。     

Comparison of ocular response analyzer,dynamic contour tonometer and Goldmann applanation tonometer

The aim of this study was to compare the intra-ocular pressure (IOP) obtained by ocular response analyzer (ORA), dynamic contour tonometer (DCT) and Goldmann applanation tonometer (GAT). In 102 patients (47 with primary open-angle glaucoma and 55 healthy controls) IOP was measured with GAT, ORA and DCT in one eye. The agreement between GAT, DCT and ORA values was assessed using Bland–Altman plots. The discrepancy between the methods was related to central corneal thickness (CCT), corneal hysteresis (CH) and corneal resistance factor (CRF) using linear regression models. Significant differences were observed amongst DCT, corneal compensated ORA (ORAcc) and GAT (P < 0.01). Only the ORAcc and DCT were comparable. ORAcc and DCT significantly over-estimated IOP compared to GAT and for ORAcc this difference depended on the height of IOP. A significant correlation was found between CCT and the deviation of DCT and ORAcc from corrected GAT (both P < 0.0001). Our study showed a low degree of agreement between IOP measured by ORA, DCT and GAT. DCT and ORAcc over-estimated the IOP compared to GAT.     

The Pulsair-Keeler non-contact tonometer in self-tonometry: preliminary results

The authors considered the possibility of using the Pulsair-Keeler non-contact tonometer in self-tonometry.For this reason, 45 patients have been trained to use the instrument and, after a reasonable trial period, were able to self-measure their IOP,The results have been compared to the tonometric values measured with Goldmann tonometer to evaluate statistically the limits and the dependability of this method of measurement.The results shows that self-tonometry with the Pulsair-Keeler tonometer can be used in monitoring glaucomatous patients at home.     

动态轮廓眼压计与非接触眼压计在正常青年人坐位眼压昼夜波动趋势的研究

目的:采用PASCAL动态轮廓眼压计(dynamic contour to-nometer,DCT)及KEELER非接触眼压计(non contact to-nometer,NCT)对一组健康青年昼夜眼压进行监测,描述其波动规律,并比较两种方法异同。方法:以PASCAL动态轮廓眼压计对一组19～22岁健康青年27例(54眼)进行24h眼压监测;以KEELER非接触眼压计对一组19～22岁健康青年84例(168眼)进行24h眼压监测。测量自早晨08∶00开始至次日凌晨06∶00,每隔2h为一个观察时间点,每个时间点测量3次,以平均值作为该时间点眼压。结果:DCT法与NCT法所测得的眼压平均值分别为15.76±2.37mmHg和13.77±4.33mmHg,DCT组眼压均值的最高值出现在08∶00,最低值出现在20∶00;NCT组眼压均值的最高值出现在06∶00,最低值出现在22∶00。DCT组双眼眼压波动值分别为:左眼4.56±1.19mmHg,右眼4.12±1.21mmHg;NCT组双眼眼压波动值分别为:左眼4.71±2.23mmHg,右眼5.00±1.50mmHg,两种方法左右眼间眼压值差异无统计学意义(F=0.668,P=0.415),男女眼压值差异无统计学意义(F=1.459,P=0.229),12个时间点之间眼压值差异有统计学意义(F=64.407,P=0.000),且变化趋势呈为二次抛物线,两种方法随时间变化趋势有统计学意义(F=16.615,P=0.000)。结论:正常青年眼压呈昼夜节律变化,于白昼结束时最低,夜晚结束时最高。不同的测量方法在各时间点所得测量值及昼夜变化趋势上存在差异,且采用动态轮廓眼压计在多个时间点上均比采用非接触眼压计所测值高。临床上在应用眼压作为原发性青光眼诊断和疗效判断时,应注意测量时间及方法选择上的差别。