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1.
Tumorigenesisproceedsthroughanaccumulationofspecificgeneticalterations Recentstudieshavefocusednotonlyonthederegulationofcellproductionbutalsoontheinhabitationofcellloss Thisstudyassessedtherelationshipbetweenapoptoticstatusandbiologicalbehaviorduring…  相似文献   

2.
Molecular genetic analysis of a Chinese patient with Fabry disease   总被引:4,自引:0,他引:4  
FabrydiseaseisanX linkedlysosomalstoragediseasecharacterizedbyaccumulationofglycosphingolipidsinendothelialcells,fibroblasts,smoothmusclecells,andepithelialcellsofthekidney Thereisacharacteristicskinlesion,angiokeratomacorporisdiffusumuniversalis,whichc…  相似文献   

3.
Itisdifficulttoblockthetransmissionofschistosomiasisbychemotherapy ,thereforemanyresearchershavebeeninterestedinthestudyofvaccineofschistosomiasis Thestudyofvaccineofschistosomiasiswasmostlyfocusedonanti infectionimmunity ,butthemosthopefulcandidatemole…  相似文献   

4.
Ithasbeenreportedthattheclassicalmodelofthedominanceofthelefthemisphereofhumanbrainisincorrectbecauseitisinaccuratetosaythatwhichhemisphereisdominant Thehemispheresareasymmetricalintheirfunction Inthisstudywetriedtofindouttheactivatedareasandtoconfirm…  相似文献   

5.
CelladhesionmoleculesmaymediatethechemotacticmigrationbetweencellsorcellsandinterstitiumRecentstudies1,2havefoundthatdialysiswithcellulosemembranescouldleadtochangesintheexpressionofleukocyteadhesionmolecules,suchasCD11bandLselectin,ongranulocytesandmon…  相似文献   

6.
Woundhealingistheprocessbywhichcellproliferationisstringentlycontrolled ProgressionthroughtheG1phaseandinitiationofthecellcycleinmammaliancellsdependsonthebalanceofinteractionbetweencellcyclepositiveregulatorssuchascyclinD1,cyclinE ,cyclin dependentkina…  相似文献   

7.
Lymphangiomyomatosis   总被引:1,自引:0,他引:1  
Lymphangiomyomatosis (LAM )isaprogressivediseaseaffectingwomenofchildbearingage Itismicroscopicallycharacterizedbyabnormalsmoothmuscleproliferationthatcausesgradualobstructionofsmallairways ,lymphaticsandvasculature Theproliferationeventuallyresultsinach…  相似文献   

8.
Chroniccutaneousulcersrepresentamajorhealth careproblemwithconsiderablesocioeconomicimpact 1,2Traditionally,localtreatmentofchroniccutaneousulcersconsistsofconstantlocalwoundcare ,surgery ,skingrafting,debridementandvascularreconstruction Chroniculcersmayi…  相似文献   

9.
Chronicperiodontitisisaverycommonoraldisease Sinceitisadifficultdiseasetocure ,itattractstheattentionofmanyresearchers Recentstudiessuggestthatimmunocompetencesubstancespresentinthehumanbodyareimportantfactorsinphysiologicalfunctionanddemonstratethatel…  相似文献   

10.
TGF-β1基因转染修饰人退变腰椎间盘髓核细胞   总被引:1,自引:0,他引:1  
Degenerationofthelumbardiscaffectsthemechanicalpropertiesofthespineandisrelatedtoclinicallowbackdisorders Thelimitedavailabletechnologygenerallyishighlyinvasiveandusuallydiscectomyisinvolved ,whichoftencompromisesthestructuralintegrityofthespine Longte…  相似文献   

11.
TheresearchgroupledbyProfessorWuYiminghasbeenengagedintheresearchofprofessionaltumorformanyyears ,especiallyengagedintheresearchofcharacteristicsoflungtumorcausedbypolyaromaticcompounds ,carcinogen esismechanismandtheresearchofearlydiagnosisofprofessio…  相似文献   

12.
Theuterinecavitycommunicateswiththeexternalenvironmentandisthereforeexposedtoforeignantigens Itdoesnothaveacomplexstructureoflymphnodesandretainsthecharacteristicsofaprimitivesurfaceepithelia 1Previousstudieshavedemonstratedthepresenceoflymphocytesint…  相似文献   

13.
Objective Toestablishadiagnosticcriteriaofparasystolewithhighsensitivityandhighspecificity-Methods Afterexcludedfromnonparasystoleandeachvariantparasystoles,basedontheelectrocardiographicdataobtainedfrom61patientswithclassicparasystole,weselectedtheq…  相似文献   

14.
Repair of stricture of cervical esophagus with platysma myocutaneous flaps   总被引:5,自引:0,他引:5  
Itisverydificulttoachieveasuccesforscarstenosisofthecervicalesophagusandanastomoticstenosisaftercolonorstomachtranspositionto...  相似文献   

15.
Osteoporosis(OP)isacommonmetabolicdiseaseofbonecharacterizedbylowbonemass,microarchitecturaldeteriorationofbonetissueleadingtohighbonefragilityandriskinfracturewithage.Itishardtobecured,unclearinpathogenesis,andhasbecomeaserioussocialproblemsinceitth…  相似文献   

16.
Itisknownthatdiabetesmaybeac-companiedbysuchvascularchangesasarte-riolarhyalinedegenerationandbasemem-branethickening,whichcanresultinvesselstricture.Buttheexactmechanismofdia-beticangiopathyremainsunclear.ItwasnotedthatAGEsproductionwasacceleratedan…  相似文献   

17.
Vaccinesarethemosteconomicandef-fectivetoolsinpreventionofdiseases.BCGhasfollowinguniquefeatures:Theproductscanbeusedinimmunityprotectiveexperi-mentdirectlywithoutpurificationandpro-cedureissimpleandcheap;simpleonevac-cinationcaninduceimmunitycontinu…  相似文献   

18.
Hepaticangiosarcomaisararemalignantvasculartumor Accuratepreoperativediagnosisofthistumorisverydifficultifthepatientdoesnothaveanyhistoryofexposuretospecificcarcinogensincludingthorotrast,arsenicalsandvinylchloridemonomer WedescribeCTfindingsintwocase…  相似文献   

19.
Transplantationofpancreaticisletoflangerhansisarapidlygrowingareainmedicalresearchwithapromiseofclinicalapplication1 Themajorprogressesareasfollows:1microencapsulationdonorisletforimmunoisolationavoidtheacuterejection,butthechronicrejectionandinnutriti…  相似文献   

20.
Atherosclerosisanditsconsequencesaccountformostmorbidityandmortalityintheworld.Anumberofepidemiologicalstudieshavedemon stratedaninverserelationshipbetween plasmahigh densitylipoprotein (HDL)concentrationandtheincidenceofatherosclerosis[1 ] .Itiswidelyac ce…  相似文献   

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