儿童难治性腮腺气肿1例报道及文献回顾

目的 探讨腮腺气肿的治疗方法,为临床提供参考。方法 报道1例儿童难治性腮腺气肿,结合文献对腮腺气肿的诊疗进行回顾分析。结果 该例患儿无明显诱因腮腺肿大1个月余,经抗炎治疗、心理干预治疗、物理加压治疗等保守治疗后无效,患儿既往有脑瘫伴癫痫病史,存在非自主性鼓颊行为,考虑为难治性病例。经腮腺导管结扎及腮腺浅叶部分切除术后得到根治。文献回顾表明,腮腺气肿是一种罕见的腮腺肿大,多为口腔内压力增加引起空气经腮腺导管返流入腮腺内所致,其诊断主要依靠间歇性的腮腺肿胀等临床表现及超声、CT、MRI、造影等影像学检查手段。现阶段治疗措施主要包括保守抗炎治疗、物理治疗、心理干预,手术治疗是难治性腮腺气肿的最终治疗手段。结论 腮腺气肿有进一步发展为腮腺炎症的可能,一般采取保守治疗,对于一些重症、复发性以及依从性差的病例,需要进行手术治疗。     

腮腺腺鳞癌1例报告及文献复习

腮腺腺鳞癌是一种罕见的高度恶性肿瘤,本文报告1例发生于61岁男性患者的腮腺腺鳞癌,并结合文献对其临床和病理特征、诊断和治疗等进行讨论。     

涎腺导管癌9例报道及文献复习

目的：探讨涎腺导管癌临床病理学特征、治疗方法及预后。方法：结合我院近十年收治的9例涎腺导管癌病例,回顾国内详细记载涎腺导管癌病例报告,对其发病特点、临床表现、组织病理学特征、治疗方法和预后情况进行分析。结果：涎腺导管癌好发于老年人,以腮腺导管癌多见,临床上表现为质硬、界限不清肿块,常伴有神经侵犯症状。主要病理学特征是导管样细胞巢呈实质性、筛孔状和乳头状结构,中心有粉刺样坏死。治疗以手术扩大切除加颈淋巴清扫术为主,辅以术后放疗或化疗。术后易复发,颈淋巴结转移率高,常发生远处转移。结论：涎腺导管癌是一类较少见,且恶性程度很高的涎腺恶性肿瘤,预后较差,癌基因C-erbβ2和p53检测可能对判断早期局部复发、远处转移和生存率有所帮助。     

副腮腺肿瘤：附17例报告

作者对该院近十年收治的１７例患者进行了回顾性临床分析，副腮腺肿瘤的临床特征：凡位于颊中部肿块在排除了中胚叶来源的肿块后应考虑本瘤的可能；肿瘤靠近腮腺导管并与之相联；组织学证实是腮腺来源的肿瘤等是诊断依据，手术治疗采用腮腺区类Ｓ形延长切口为宜，良性肿瘤行局部切除即可；而恶性肿瘤则以扩大切除的手术为主。     

腮腺皮脂腺癌1例报告及文献复习

皮脂腺癌是极为罕见的恶性肿瘤,以眼睑多发,发生于唾液腺者甚为少见,主要发生于腮腺。本文旨在报告1例发生在61岁男性右侧腮腺区的皮脂腺癌,并根据国内外文献报告,对其临床表现、诊断、组织学特点、治疗及其预后做进一步的探讨。     

腮腺导管瘘及腺体瘘的病因分析和治疗

本文总结了５２例腮腺导管瘘及腺体瘘的病因与治疗。本组病例中，腺体瘘３２例占６１．５％，导管瘘２０例，占３８．４％，通过病因分析．作者认为在施行腮腺部位的外伤清创术，腮腺范围肿瘤摘除术，以及腮腺区脓肿切排等手术时，应注意到腮腺部位的解剖特点。正确的手术切口，选择合适的手术方法，外伤后对腺体导管检查和处理是避免或减少腮腺导管瘘及腺体瘘发生的重要因素。     

腮腺嗜酸细胞腺癌1例报告

嗜酸细胞腺癌是WHO涎腺肿瘤组织学1991年分类中提出的一种罕见的肿瘤.我科收治一例,报道如下:     

腮腺主导管囊肿1例报告

腮腺囊肿是一种相对少见的唾液腺囊肿,分为潴留性囊肿与先天性囊肿,在腮腺主导管形成的潴留性囊肿极为罕见。本文报告1例37岁男性病例,表现为右侧颊部的无痛性肿物,全麻下行腮腺浅叶切除术,术后组织病理学检查证实为腮腺主导管囊肿。本文结合有关文献,对其病因、病理学特征、鉴别诊断和治疗等进行讨论。     

腮腺T细胞淋巴瘤1例报告及文献复习

腮腺T细胞淋巴瘤是一种罕见病,其临床表现不典型,可通过组织病理学和免疫组织化学染色检查明确诊断。本文报告1例腮腺T细胞淋巴瘤病例,并结合相关文献对其发病情况、诊断、治疗及预后等进行复习。     

Madelung病:病例报告与文献复习

回顾性分析1 例Madelung病患者的病例资料,讨论此病病因,临床表现和治疗方法.该病病因不清,多发男性,肿块对称性地分布在头、颈及上躯干皮下的多个部位,呈现"马颈"或"驼峰"样外形,组织病理学表现为脂肪样组织沉积.目前手术是主要治疗手段,其预后较好.     

Desmoplastic ameloblastoma: A case report and literature review

The desmoplastic ameloblastoma is a rare histologic variant of ameloblastoma. This article presents a case of desmoplastic ameloblastoma with unique and complex histologic findings. The tumor, which was located in the anterior mandible, was treated by an anterior marginal resection with preservation of the inferior border of the mandible. The clinical, radiographic, surgical, and pathologic aspects of this unusual lesion are presented, and the relevant literature is reviewed.     

Crouzon's syndrome: A review of literature and case report

Crouzon's syndrome is an autosomal dominant disorder with complete penetrance and variable expressivity. Described by a French neurosurgeon in 1912, it is a rare genetic disorder. Crouzon's syndrome is caused by mutation in the fibroblast growth factor receptor 2 (FGFR2) gene. Normally, the sutures in the human skull fuse after the complete growth of the brain, but if any of these sutures close early then it may interfere with the growth of the brain. The disease is characterized by premature synostosis of coronal and sagittal sutures which begins in the first year of life. Case report of a 7 year old boy is presented with characteristic features of Crouzon's syndrome with mental retardation. The clinical, radiographic features along with the complete oral rehabilitation done under general anesthesia and preventive procedures done are described.     

Partial craniofacial duplication: A review of the literature and case report

Diprosopus (Greek; di-, “two” + prosopon, “face”), or craniofacial duplication, is a rare craniofacial anomaly referring to the complete duplication of facial structures. Partial craniofacial duplication describes a broad spectrum of congenital anomalies, including duplications of the oral cavity. This paper describes a 15 month-old female with a duplicated oral cavity, mandible, and maxilla. A Tessier type 7 cleft, midline meningocele, and duplicated hypophysis were also present. The preoperative evaluation, surgical approach, postoperative results, and a review of the literature are presented. The surgical approach was designed to preserve facial nerve innervation to the reconstructed cheek and mouth. The duplicated mandible and maxilla were excised and the remaining left maxilla was bone grafted. Soft tissue repair included closure of the Tessier type VII cleft. Craniofacial duplication remains a rare entity that is more common in females. The pathophysiology remains incompletely characterized, but is postulated to be due to duplication of the notochord, as well as duplication of mandibular growth centres. While diprosopus is a severe deformity often associated with anencephaly, patients with partial duplication typically benefit from surgical treatment. Managing craniofacial duplication requires a detailed preoperative evaluation as well as a comprehensive, staged treatment plan. Long-term follow up is needed appropriately to address ongoing craniofacial deformity.     

口腔颌面部骨外黏液样软骨肉瘤1例及文献复习

对1例口腔颌面部骨外黏液样软骨肉瘤患者的临床病理资料进行回顾性分析及文献复习。本病发生于口腔颌面部的报道很少见,病理学检查诊断非常重要。单纯局部广泛切除不能根治,应采取综合治疗,术后需长期随访。     

Glandular odontogenic cyst: A case report and literature review

In 1992, the World Health Organization (WHO) named glandular odontogenic cyst (GOC) as an independent pathologic entity and classified it as a developmental odontogenic epithelial cyst.^1,2 The WHO defined this lesion as “a cyst arising in the tooth-bearing areas of the jaws and characterized by an epithelial lining with cuboidal or columnar cells both at the surface and lining crypts or cyst-like spaces within the thickness of the epithelium.”¹GOCs occur over a wide age range in both sexes and in either jaw, and have the propensity to recur and to become large. Radiographically, the GOC appears as an intrabony, unilocular or multilocular, sometimes honeycomblike, well-defined radiolucent lesion. Histologically, the lining epithelium may be partly squamous, without distinctive features.¹ However, in many areas, the stratified epithelium has a surface layer of eosinophilic cuboidal or columnar cells, often forming irregular papillary projections.¹ A variable number of ciliated and mucus-producing cells may also be interspersed in the surface layer.¹ Within the thickness of the epithelium there may be crypts and glandular or cystlike spaces lined by cells similar to those seen in the epithelial surface.¹ Pools of mucous material within the intraepithelial spaces and within the main cyst cavity are a prominent feature. Plaquelike and whirlpoollike epithelial thickenings also may be present.¹ The fibrous capsule is usually free of inflammatory cells.¹ Multicystic or botryoid varieties also occur.¹ Because this lesion has been characterized only recently, and only a few cases have been reported in the literature,^3–8 its biologic nature is uncertain.^1,2 However, the aggressive behavior and the recurrent tendencies of this lesion have been suggested,^1,2 even in the limited number of reported cases.^3–8We report a case of GOC that exhibited histologic features suggesting the aggressive and somewhat neoplastic nature of this lesion. Furthermore, the clinicopathologic features of 17 cases reported in the literature^3–8 are reviewed, and the differential diagnosis of this rare lesion, especially from central low-grade mucoepidermoid carcinoma (MEC), as well as its treatment, are also discussed.     

Intraosseous mandibular hemangioma. A case report and review of the literature

Intraosseous vascular lesions are rare conditions, comprising only 0.5% to 1% of all intraosseous tumors. They mainly occur in the second decade of life especially in women. The most common locations are the vertebral column and skull; nevertheless, the mandible is a quite rare location. According to the World Health Organization, hemangiomas are benign vasoformative neoplasms of endothelial origin. However, the origin of central hemangioma is debatable. Some authors believe that it is a true neoplasm, whereas others state it is a hamartomatous lesion. Clinically, the patient may be completely symptom-free or may present discomfort, pulsatile bleeding, bluish discoloration, mobile teeth, derangement of the arch form or accelerated dental exfoliation. Most frequently radiographic finding is a multilocular radiolucent image with honeycombs or soap bubble appearance. Differential diagnosis includes neoplasms such as ameloblastoma, cystic lesions such as residual cyst, keratocyst and fibro-osseous lesions such as fibrous dysplasia. There are some therapeutic alternatives, although wide surgical excision remains as the gold standard. We now present a case report of a 51-year-old woman diagnosed in a mandibular hemangioma. Clinical, radiological and histological features of this unusual tumor are described.