Factors associated with maternal mortality in Addis Ababa, Ethiopia

A housing probability survey in which 9315 women were interviewed was conducted in 1983 to detect the incidence and aetiology of maternal mortality in Addis Ababa, Ethiopia. Maternal mortality for the two-year period from 11 September 1981 was 350/100,000 livebirths (excluding abortions). A logistic regression analysis selected antenatal care, occupation and income as risk factors for maternal mortality, after adjusting for age, parity, education and marital status. Odds ratios were 2.5 for unbooked women compared to those receiving antenatal care, about 3 for students, and maids/janitresses compared to housewives, and between 3 and 5 for those earning less than US$25 monthly, compared to those earning US$150 or more.     

Utilization of pharmacies and pharmaceutical drugs in Addis Ababa, Ethiopia

This paper examines recent developments in the pharmaceutical retail trade in socialist Ethiopia and presents the results of two surveys on pharmacy utilization in Addis Ababa. Surveys were carried out in 6 private and 5 government pharmacies. Objectives are: (1) to examine drug retailer utilization in relation to locational, transportation and retailer-related factors; (2) evaluate the role of socioeconomic factors in pharmacy and drug utilization; and (3) determine distance decay associated with clients' trip origins and the location of their residences as indicators of service areas. Although most clients originated in Addis Ababa, large numbers came from rural areas, especially in the pharmacies near large markets and other shopping areas in the inner city. Centrally located retailers also served more Addis Ababa residents and larger sections of the city than peripherally located retailers, largely due to a combination of urban structure, distribution of health care facilities, prevailing drug shopping behavior and population distribution. Government pharmacies had larger service areas and served larger numbers of clients than private pharmacies, primarily due to lower prices and greater availability of pharmaceuticals. Mean distance from pharmacies to places of origin of trips was smaller than mean distance from pharmacies to residences of the same clients. Similarly, distance decay gradients were steeper for the former than the latter in the 4 pharmacies studied in the second part of the survey, indicating the greater suitability of origin of trip as a parameter of service area. Type and price of drugs purchased were associated with socioeconomic factors, particularly level of education and housing/environmental health conditions in two districts, but there was little variation in the small number of drugs purchased per client. Several forms of drug-purchasing behavior of pharmacy clients and selling practices of private retailers are described as adaptive responses to prevailing economic and sociopolitical conditions. The study concludes that population-based studies of disease occurrence and health behavior are needed to better evaluate the health needs of the population for the planning of additional drug retailers in Addis Ababa's suburban districts.     

Perception and management of tuberculosis symptoms in Addis Ababa, Ethiopia

Management of early tuberculosis (TB) symptoms and adherence to medical treatment are main challenges in controlling TB. The aim of this study is to explore how symptoms of TB are perceived and managed, from the onset of symptoms and during the course of treatment, in Addis Ababa, Ethiopia. We conducted a qualitative interview study, including 50 in-depth interviews and 2 focus groups, with TB patients, their relatives, and health personnel. We found that a patient's perceptions and self-treatment of early symptoms could cause diagnostic delay. Stigma associated with TB and public health services made many patients approach private clinics, causing further delay. Both private and public clinics often labeled and managed symptoms according to lay explanatory models. Lack of adequate knowledge about TB's etiology and cure caused patients to continue relating to symptoms by reference to their own understanding. This affected patients' ability to manage TB and its treatment.     

Demographic impact of AIDS in a low-fertility urban African setting: projection for Addis Ababa,Ethiopia

The study estimated the potential demographic impact of acquired immunodeficiency syndrome (AIDS) in a low-fertility urban setting in sub-Saharan Africa. The prevalence of human immunodeficiency virus (HIV) projected using a deterministic mathematical model was put into the AIDS Impact Model (AIM) of the SPECTRUM Policy Modelling System to estimate the potential demographic impact ofAIDS in Addis Ababa, Ethiopia. Demographic indicators from 1984 (the start of the HIV epidemic in Ethiopia) to 2024, including and excluding the HIV epidemic, were compared. Addis Ababa is experiencing a demographic transition in which the total fertility rate has declined from 3.8 to below replacement level over the last 20 years. The prevalence of HIV is predicted to stabilize at 10% in adults, resulting in a total number of people living with HIV at 200,000 and a cumulative number of deaths due to AIDS at 50,000. About 60% of adult deaths can be attributable to AIDS by 2000. The epidemic is predicted to reduce life expectancy by 10 and 17 years in 2000 and 2024 respectively, and to turn to negative, the rate of natural increase after 2009. Accordingly, the rate of natural increase will be -0.18%, -0.35%, and -0.71% per annum by 2009, 2014, and 2024 respectively. Population growth is expected to continue with or without HIV, as a result of high net in-migration, although data for migration are scanty. In a low-fertility urban society of Africa, this study shows the potential for the HIV/AIDS epidemic to turn the rate of natural increase to negative.     

Differential use of adolescent reproductive health programs in Addis Ababa,Ethiopia

PurposeAdolescent reproductive health programs in Africa have largely remained as small-scale pilot programs, however, there is increasing interest in bringing programs to scale. Evaluations have focused on individual programs and few have gathered population-based information on the reach of program models and the profile of adolescents who utilize services, versus those who do not. This study examines the coverage and utilization of existing adolescent programs in Addis Ababa, Ethiopia.MethodsPopulation-based surveys were undertaken among over 1000 adolescents aged 10 to 19 years in slum areas of Addis Ababa, Ethiopia. An inventory of youth programs including youth centers and peer education programs was compiled in the study area.ResultsEight peer education programs and six youth centers were operating in the study area. Twenty percent of boys and only 7% of girls had visited a youth center in the last year; 27% of boys and 15% of girls had had contact with a peer educator. Older adolescents, especially boys, were more likely to utilize programs. Girls who work long hours and who are isolated are less likely to access and benefit from programs.ConclusionsGreater segmentation of the adolescent population is needed in the design and content of adolescent reproductive health programs. In addition, programmers should pay attention to the specific circumstances of young people in local settings, particularly vulnerable, hard-to-reach sub-groups of adolescents, including girls.     

Mass Hysteria among Beneficiary Students of the School-Feeding Program in Addis Ababa,Ethiopia

BackgroundMass hysteria is described as the rapid spread of conversion disorder without organic basis among a group of people. Mass hysteria can occur in work place and commonly in schools. There are usually some factors attributable to the episode; however, the lack of a pathogen upon investigation is a fundamental characteristic. We are reporting an episode of mass hysteria from two schools in Addis Ababa, Ethiopia.MethodsClinical record, laboratory investigation, toxicology study from the food and psychiatric evaluations.ResultsOn November 25, 2019 a total of 113 students were brought from two schools in Addis to Tikur Anbessa Specialized Hospital. Most were between the ages of 10 and 15 years and were female students. Their school breakfast of bread and marmalade was attributed as the cause of the episode; however only 49% of the students brought in had eaten the food. The majority complained of nausea and vomiting but most had normal physical finding; and their symptoms were resolved without treatment. The laboratory investigation on samples of blood and stool were negative for bacterial growth and food culture and toxicology were non-revealing. Most were reassured and few were given symptomatic treatment.ConclusionThis mass hysteric episode is similar to episodic reports from other school feeding programs in some Asian and African countries. The finding of this report is important for health care practitioners to consider mass psychogenic illness in case they face similar mass presentation without objective finding; and will help to avoid unnecessary costly investigations.     

The proximate determinants of the decline to below-replacement fertility in Addis Ababa,Ethiopia

Between 1990 and 2000, the total fertility rate (TFR) in Ethiopia declined moderately from 6.4 to 5.9 children per woman of reproductive age. During the same period, the TFR in the capital city of Addis Ababa declined from 3.1 to 1.9 children per woman. Even more striking than the magnitude of this decline is that it occurred in the absence of a strong and effective national family planning program. In this study, the components of this fertility decline are identified using the Bongaarts framework of the proximate determinants of fertility. The results of a decomposition analysis indicate that a decrease in the age-specific proportions of women who are married, followed by an increase in contraceptive use are the most important mechanisms by which fertility has declined in Addis Ababa. Poor employment prospects and relatively high housing costs are likely factors that encourage couples to delay marriage and reduce marital fertility.     

Illness and health behaviour in Addis Ababa and rural central Ethiopia

This paper examines the results of health surveys among 544 randomly selected households (2829 people) in seven kebele (urban dwellers' associations) in Addis Ababa and Kaliti, an industrial suburb of Addis Ababa, and in four rural villages in two peasant associations. The major objective was to study illness distribution and health behaviour among different socioeconomic and cultural groups in urban and rural communities within the context of available health resources, national health policy and planning. Results show that in spite of the rapid expansion of health services since the Ethiopian revolution serious problems of allocation and access persist. Higher illness prevalance rates were found in rural areas (23.2%), Kaliti (25.5%) and in the low socioeconomic kebele in Addis Ababa (23.9%) than in the high socioeconomic kebele (16.5%), but rural/urban and intraurban differences were greater than reported here due to underreporting. One-third of all illnesses were treated by modern services, 19.9% by self care and 26.0% by traditional medicine and transitional healers, with 21.5% of all illnesses not being treated. Utilization rates varied with type and duration of illness, socioeconomic level, age, sex and place of residence. The role of distance and other contact barriers, treatment outcome and availability of private clinics and alternative health resources in utilization is also evaluated. Coverage of the modern health services was associated with socioeconomic status and mobility of patients as well as availability of health services.     

Seroepidemiology of measles in Addis Ababa,Ethiopia: implications for control through vaccination

We undertook a representative survey of measles antibodies in Addis Ababa, Ethiopia 1994, to characterize immunity and transmission. Specific-antibody levels (IU/l) were determined by ELISA for 4654 sera from individuals aged 0-49 years (1805 < 15 years) collected by stratified household-cluster sampling. The proportion seronegative (< 100 IU/l) was 20% (95% CI: 16-25) in children 9-59 months old, declining to 9% (7-12) in 5-9 year olds, 5% (4-7) in 10-14 year olds, and < 1% in adults. The proportion of children (< 15 years old) with low-level antibody (100-255 IU/l) was 8% (7-10). Vaccination and an absence of a history of measles illness were strongly associated with low-level antibody. History of measles vaccination in 9 months to 14-year-old children was approximately 80%. We estimate a primary vaccine failure rate of 21% (12-34) and continued high measles incidence of 22 per 100 susceptibles (19-24) per annum. Our data support the introduction of campaign vaccination in the city in 1998, although higher routine vaccine coverage is required to sustain the impact. The implications of a high prevalence of low-level antibody are discussed.     

Precursors of atherosclerotic and hypertensive diseases among adolescents in Addis Ababa, Ethiopia.

The present study measured the prevalence of the precursors of atherosclerosis among 519 adolescents selected from high-school students in Addis Ababa. Also assessed was their knowledge about these precursors and about the hazards of smoking and of heavy alcohol consumption. A total of 13.8% of the adolescents smoked, 11.6% had a sedentary lifestyle, 9.2% consumed alcohol heavily, 14.1% were obese, 30.3% had one risk factor, and 4.4% had two risk factors for atherosclerosis. Altogether, 58% had inadequate knowledge about the precursors of atherosclerosis, and 62% and 51.4%, respectively, had inadequate knowledge about the hazards of smoking and of consuming alcohol. High-risk behaviours were positively associated with upper-income families and inadequate knowledge about the precursors of atherosclerosis. A substantial proportion of adolescents in Addis Ababa therefore exhibit the precursors of atherosclerotic and hypertensive diseases. Further, similar studies should be carried out in other Ethiopian cities, and the Ministries of Health and Education should give due attention to the primary prevention of these diseases and formulate plans for appropriate actions.     

Oral and anal sex practices among high school youth in Addis Ababa,Ethiopia

Background  

Understanding the full range of sexual behaviors of young people is crucial in developing appropriate interventions to prevent and control sexually transmitted infections including HIV. However, such information is meager in developing countries. The objective of this study was to describe oral and anal sex practices and identify associated factors among high school youth.     

Pre-hospital Care to Trauma Patients in Addis Ababa,Ethiopia: Hospital-based Cross-sectional Study

BackgroundTrauma is a major cause of morbidity and mortality worldwide. Prompt use of pre-hospital care is associated with reduced early and late morbidity and mortality from trauma. This study aimed to assess the time to reach the facility and the pattern of pre-hospital care provided for trauma patients.MethodsA cross-sectional study design with a structured interview questioner was used for patients presenting to Addis Ababa Burn Emergency and Trauma Hospital Emergency Department from April 1 to May 30, 2020.ResultOut of 238 interviewed patients, the most common means of transportation from the scene to the initial health facility were taxi 77(32.4%) and ambulance 54(22.7%). The time of arrival from the scene to the initial health care facility was within one hour, 133(56.1%) and in 1–3 hours 84(35.5%). Some form of care was provided at the scene in 110(46.2%) of cases. The care provided was bleeding arrest 74(31.1 %), removing from wreck 51(21.4%), splinting/immobilizing injured area 38(16%), position for patient comfort 19(8%), and others. Relatives were the most common care provider 49(45%) followed by bystanders 37(33.9%), trained ambulance staff 19(17.4%), and police 2 (1.8%). The main reasons for not providing care were lack of knowledge 79(61.2%), and lack of equipment 25 (19.4%).ConclusionThe study showed relatives and bystanders were the first responders during trauma care. However, ambulance utilization for pre-hospital care was low. There was trauma patients delay to arrive to hospital. Only half of the patients presented to the health facility within Golden hour.     

Brain Magnetic Resonance Imaging Findings in Patients with Developmental Delay in Addis Ababa,Ethiopia

BackgroundDevelopmental delay is a major health problem throughout the world causing significant individual disability. Even though physical examination and patient history are the most important and basic evaluations of patients with developmental delay, additional investigations are usually required in supporting or reaching a diagnosis among which is neuroimaging. This study aims to assess brain Magnetic resonance imaging (MRI) patterns in patients presented with developmental delay.MethodA retrospective analysis of 164 patients who had undergone brain Magnetic Resonance Imaging (MRI) evaluation for the developmental delay was done. The study was conducted between March to November 2021 G.C at Tikur Anbessa Specialized Hospital (TASH). The patients'' clinical history and magnetic resonance imaging reports were reviewed from their medical records. All patients with developmental delay who had brain MRI evaluation at TASH and at one private diagnostic center in Addis Ababa were included in the study.ResultsA total of 164 patients were included in this study of which 95(57.9%) were male and 69(42.1%) female patients were seen. A total of 120 patients (73.2%) showed abnormal brain MRI studies. Previous neurovascular insults were the most common abnormalities seen in 75(45.7%) patients followed by imaging findings of congenital and developmental abnormalities seen in 20(12.2%) patients.ConclusionBrain MRI is an important input in the evaluation of patients with developmental delay. It can give evidence for the cause of developmental delay, especially in the diagnosis of perinatal/hypoxic-ischemic insults, and congenital and developmental malformations.     

Seroepidemiology of hepatitis B virus in Addis Ababa,Ethiopia: transmission patterns and vaccine control

A community-based seroepidemiological survey of Addis Ababa, Ethiopia was conducted in 1994 to inform on the transmission dynamics and control of hepatitis B virus (HBV) infection. Venous blood from 4736 individuals under 50 years of age from 1262 households, selected using stratified cluster-sampling, was screened for HBV markers using commercial ELISAs. HBsAg prevalence was 7% (95 % CI 6-8), higher in males (9%; 7-10) than females (5%; 4-6). HBeAg prevalence in HBsAg positives was 23% (18-29), and less than 1% of women of childbearing age were HBeAg positive. Overall HBV seroprevalence (any marker), rose steadily with age to over 70% in 40-49 year olds, indicating significant childhood and adult transmission. Estimated instantaneous incidence was 3-4/100 susceptibles/year, higher in males than females in 0-4 year olds, and peaking in early childhood and young adults. The age at which 50% had evidence of infection was around 20 years, and the herd immunity threshold is approximated at 63-77%. Addis Ababa is of intermediate-high HBV endemicity, with negligible perinatal transmission. Our main findings are the identification of a significant difference between males and females in the age-acquisition of HBV infection, and marked differences between age groups in HBV incidence rates. These results should target future research studies of underlying risk factors. Furthermore, we generate a crude estimate of the level of coverage of HBV vaccine that would be required to eliminate the virus from the study population.     

Prevalence of hepatitis B infection among hospital personnel in Addis Ababa (Ethiopia)

Hepatitis B serological markers (HBsAG, anti-HBc and anti-HBs) were determined in 432 (60%) hospital employees by the Hepanostika microenzyme linked immunoassay method.The overall prevalence rate was 9.02% for HBsAg, 46.25% for anti-HBs, 73.6% for anti-HBc and 76.38% for at least one marker positive. Marker positivity as well as HBsAg carrier rate is higher for males than for females. (82.0 Vs 69.9%; 11.4 Vs 6.75% respectively). The majority of the infections occur early in life, 75% being positive for at least one marker by age twenty. The distribution of markers is somewath different from previous observations with non-hospital personnel.Departments most exposed to blood and certain job categories seem to be an increased risk of acquiring the infection.We conclude that hospital exposure is associated with an additional risk of hepatitis B infection.