Surgical treatment for small bowel metastasis of pleomorphic carcinoma 6 months after pulmonary resection

The prognosis of patients with distant metastases of pulmonary pleomorphic carcinoma is poor. We report a case of pulmonary pleomorphic carcinoma patient who underwent surgical resection of small bowel metastasis. A 69-year-old man developed anemia secondary to melena 6 months after right upper lobectomy for pulmonary pleomorphic carcinoma and small bowel metastasis was detected endoscopically. He underwent laparoscopic ileocecal resection and has survived for 2 years after lung cancer resection without any other recurrence or metastasis.     

60例肺多形性癌的外科治疗

目的 探讨肺多形性癌的外科治疗并分析影响预后的因素,以期提高对肺多形性癌的认识.方法 回顾性分析上海市胸科医院胸外科1999年至2011年收治的60例肺多形性癌临床资料,男性55例,女性5例;年龄45～77岁.周围型肺癌55例,中央型5例.54例行完全切除(R0);6例行肉眼根治切除,但镜下显示切缘阳性(R1).术后均随访.Kaplan-Meier法计算生存率,Logrank法进行生存率显著性检验,Cox比例风险回归模型进行多因素分析.结果 全组无手术死亡.1例手术当日因血胸行再次开胸止血;1例右上叶支气管袖形切除术后半年因吻合口瘢痕增生导致右余肺不张而行右余肺切除术.60例患者3年、5年生存率分别为47.2％、25.6％.本组患者中无淋巴结转移患者(25例)3年、5年生存率分别为57.3％、32.5％,淋巴结转移者(35例)3、5年生存率为25.4％、17.1％,有无淋巴结转移的患者3年、5年生存率差异有有统计学意义(P=0.017).根治性切除(R0)3年、5年生存率51.5％、30.3％,非根治性切除3年、5年生存率12.5％、0.多因素分析显示,影响预后的独立因素是手术根治程度(P=0.041)及有无淋巴结转移(P =0.029).结论 肺多形性癌预后差,应早期手术.手术根治程度和有无淋巴结转移是患者预后的独立预测因子.     

Radical resection of a pulmonary blastoma involving the pulmonary artery.

Pulmonary blastoma is a rare malignant lesion with a poor prognosis. We described a case of a 47-year-old woman with a large biphasic pulmonary blastoma, involving the left pulmonary artery. Under cardiopulmonary bypass, it was treated with radical left intrapericardial pneumonectomy and pulmonary thromboendarterectomy. Subsequent chemotherapy and radiotherapy was used. Three years postoperatively, the patient was clinically and radiologically free of tumor.     

Surgical resection of right atrial neurilemoma extending to pulmonary vein.

An asymptomatic cardiac neurilemoma was found in a 33-year-old woman. The tumor was on the anterior surface of the right atrium extending to the right upper pulmonary vein across the interatrial groove. The tumor was resected completely and right atrium, interatrial septum, left atrium and right superior pulmonary vein were reconstructed with cardiopulmonary bypass. The patient recovered uneventfully and had no recurrence 1 year after the operation. We reviewed ten reported cases of cardiac neurilemoma, including our patient.     

浸润门静脉区域的癌肿整块切除的临床研究

目的 许多近、远端胆管癌及壶腹周围癌的病人因血管受侵犯而丧失手术切除机会，本研究为提高手术切除率，延长生存期，改善病人生活质量而设计。方法 1990年3月～1996年10月，作者对50例近端胆管癌切除术和47例壶腹周围癌胰十二指肠切除术中的19例浸润了门静脉的患者，分别采用联合门静脉长度1．0～1．5cm；门静脉与腑系膜上静脉及脾静脉汇合部切除5例，切除长度2.0～4.0cm，门静脉侧壁切除5例。均行对端吻合成功。结果 19例中，17例恢复顺利，随访4～29个月，平均14个月，四例生存时间超过一年。围手术期死亡2例(10.5%)。结论 癌肿浸润门静脉主干不超过2cm，浸润门静脉及肠系膜上静脉汇合部不超过5cm，无远处转移，可联合门静脉切除并行对端吻合是可行的。     

Surgical treatment of pleomorphic carcinoma of the pancreas

Pleomorphic carcinoma of the pancreas is a rare malignancy that carries a poor prognosis. This case describes a patient with a pleomorphic carcinoma of the head of the pancreas, cured by a pylorus sparing pancreaticoduodenectomy. The literature is reviewed with emphasis on the surgical cures reported. The giant cell variety of pleomorphic carcinoma may carry a better prognosis. Pleomorphic histology of pancreatic neoplasms is not a contraindication for surgical resection.     

Clinicopathological investigation of pulmonary pleomorphic carcinoma

Background: Pleomorphic carcinoma is an uncommon malignant tumor of the lung. As there are few large-scale studies of patients with pleomorphic carcinoma, the clinical characteristics and behavior of the disease have been unclear until now. In this study, we investigated the clinicopathological findings and prognosis of 21 patients with pleomorphic carcinoma. Patients and methods: We identified 930 cases of pulmonary carcinoma in which the patient underwent a lung resection in our institute between January 1999 and June 2007. Of those patients, 21 (2.6%) were diagnosed with pleomorphic carcinoma as determined by the three pathologists in our institute. Results: The 21 study subjects consisted of 18 male and 3 female patients. The locations of the lesions were as follows: 13 cases, right upper lobe; 5 cases, left upper lobe; 2 cases, right lower lobe; and 1 case, left lower lobe. The mean diameter of the tumor in this series was 55.2 mm (17–100 mm). As for the pathological stage, four cases were stage IA, seven cases were stage IB, five cases were stage IIB, two cases were stage IIIA, and three cases were stage IIIB. The overall 5-year survival rate was 80.0%. There were no significant differences between the symptomatic group and the asymptomatic group, or between the p-factor positive group and the p-factor negative group. On the other hand, there was a significant difference in the disease-free survival rate between the node negative group and the node positive group, and there was also a significant difference in the overall survival rate between the curative operation group and the non-curative operation group. Conclusions: In this clinical study, the presence of lymph node metastasis and the treatment by a curative resection of the tumor were the most important prognostic factors for pulmonary pleomorphic carcinoma. However, further investigation of a large number of cases is needed in order to gain a clearer understanding of the clinical characteristics and behavior of pleomorphic carcinoma.     

Surgical resection of hepatic and pulmonary metastases from colorectal carcinoma

BACKGROUND: Patients with hepatic and pulmonary metastases from colorectal cancer (CRC) may benefit from aggressive surgical therapy. We examined the longterm outcomes of patients who underwent both lung and liver resections for colorectal metastases over a 10-year period. STUDY DESIGN: Four hundred twenty-three hepatectomies were performed for metastatic CRC between 1992 and 2002 at two university-affiliated hospitals. Patients who underwent both lung and liver resections for metastatic CRC were studied. Demographic, perioperative, and survival data were evaluated by retrospective chart review. Disease-free survival (DFS) and overall survival (OS) were evaluated by Kaplan-Meier analysis and survival curves were compared using the log-rank test. RESULTS: Thirty-nine patients underwent both lung and liver resections for metastatic CRC. Eleven patients (28%) underwent staged liver and lung metastasectomy from synchronously identified metastases. Twenty-eight patients (72%) underwent sequential metastasectomy because of recurrent disease. The median disease-free and overall survivals after initial metastasectomy were 19.8 and 87 months, respectively. Serial metastasectomy was common in this patient population. The mean number of metastasectomies performed was 2.6 per patient (range 1 to 4). There was no difference in overall survival for patients with synchronous versus metachronous presentation of liver and lung metastases (p=0.45). The site of first recurrence after initial metastasectomy was, most commonly, the lung (n=19, 49%), followed by the liver (n=8, 21%). Nineteen patients (49%) underwent subsequent resections for recurrences. Seven patients (18%) underwent 2 or more liver resections for recurrent disease, and 12 (31%) underwent multiple lung resections. CONCLUSIONS: An aggressive multidisciplinary surgical approach should be undertaken for recurrent CRC metastases. In selected patients, serial metastasectomy for recurrent metastatic disease is safe and results in excellent longterm survival after CRC resection.     

Surgical resection for pulmonary metastases of sweat gland carcinoma.

A case of axillary sweat gland carcinoma which metastasised to both lungs six years after resection of the primary lesion is described. The lesions were resected and three years later two further pulmonary metastases were resected.     

Surgical repair of Scimitar syndrome with azygos connection by extracardiac conduit between right pulmonary vein and left atrium

We present a surgical case of 41-year-old woman with Scimitar syndrome. Preoperative catheterization showed azygos connection and L-R shunt ratio of 45% without intracardiac malformations. To our knowledge, this combination has not been previously reported. At operation the right single pulmonary vein was found and drained into the inferior vena cava below the diaphragm. Because of counter clockwise rotation of the heart the distance of the scimitar vein and the left atrium was too long for direct anastomosis, a polytetrafluoroethylene tube (10 mm in diameter) was utilized for an extracardiac conduit using cardiopulmonary bypass. Postoperative course was uneventful. We conclude that this technique is effective for this syndrome with a large amount of L-R shunt and a sufficient patency is expected.     

Surgical resection of a renal cell carcinoma involving the inferior vena cava: the role of the cardiothoracic surgeon

Background  

The techniques for the resection of renal tumors with IVC extension are based on the experience of individual units. We attempt to provide a logical approach of the surgical strategies in a stepwise fashion.     

Gingival metastasis of pulmonary pleomorphic carcinoma; report of a case

A 71-year-old male was admitted to the hospital complaining of cough. The chest X-ray and computed tomography (CT) revealed a large tumor in the right lower lung, which was diagnosed as poorly differentiated adenocarcinoma. As the tumor grew rapidly and caused obstructive pneumonia, right middle and lower lobectomy was performed even if right gingival tumor was suspected as metastasis from lung tumor. The patient complicated with aspiration pneumonia after operation and died on the 20th postoperative day. The prognosis of lung cancer with gingival metastasis is very poor. Early detection and appropriate therapy is necessary.     

Successful surgical treatment of a posttransplantation bronchovascular fistula involving the pulmonary vein

Bronchovascular fistula is a rare complication after lung transplantation, which usually has a fatal outcome. We describe the case of successful surgical treatment of bronchovascular fistula of the left upper pulmonary vein and the left main bronchus.