星状神经节阻滞与强的松联合基础治疗急性面神经炎的比较

目的比较星状神经节阻滞与强的松联合基础治疗急性面神经炎的疗效。方法选择90例急性面神经炎患者为研究对象,采用随机数字表法分为A、B、C 3组各30例,分别接受星状神经节阻滞+基础治疗,强的松+基础治疗,星状神经节阻滞+强的松+基础治疗。比较临床症状恢复时间、面神经电生理指标、神经功能评分、治疗效果。结果 3组总有效率比较差异无统计学意义(70.00%vs 66.67%vs 73.33%,P0.05);临床症状恢复时间:3组临床症状恢复时间比较差异无统计学意义(P0.05);神经电生理指标:治疗后3组潜伏期均明显缩短,传导速度、波幅均明显增加(t=4.354~8.126,P0.05),3组间比较差异无统计学意义(P0.05);面神经功能:3组各项面神经功能评分均明显高于治疗前(t=7.684~12.857,P0.05),3组各项面神经功能评分比较差异无统计学意义(P0.05)。结论星状神经节阻滞+基础治疗,强的松+基础治疗,星状神经节阻滞+强的松+基础治疗,疗效相当,星状神经节阻滞能够替代用于急性面神经炎的治疗。     

脉冲射频联合星状神经节阻滞治疗带状疱疹性三叉神经痛疗效观察

目的观察脉冲射频联合星状神经节阻滞治疗带状疱疹性三叉神经痛的临床疗效及安全性。方法将60例确诊为带状疱疹性三叉神经痛的患者随机分为联合组(脉冲射频联合星状神经节阻滞)和对照组(星状神经节阻滞),每组30例,观察2组患者疼痛缓解程度,以视觉模拟评分(VAS)评定治疗效果和不良反应。结果 2组治疗后较治疗前VAS评分均明显降低(P<0.05),且联合组治疗后VAS评分较对照组降低更明显(P<0.05);联合组总有效率和显效率明显高于对照组(P<0.05);2组均未见明显不良反应。结论脉冲射频联合星状神经节阻滞治疗能迅速缓解带状疱疹性三叉神经痛,疗效明显优于单用星状神经节阻滞治疗者。     

星状神经节阻滞治疗颈源性头痛的临床疗效观察

目的探讨星状神经节阻滞对颈源性头痛的临床治疗效果。方法选择56例颈源性头痛患者进行星状神经节阻滞治疗，观察其临床治疗效果。结果56例患者中有40例治疗后获得明显的治疗效果，治疗前后差异有显著性意义（P〈0．01）。结论颈源性头痛的产生与颈部的交感神经受激有关，星状神经节阻滞是颈源性头痛的一种有效的治疗方法。     

2型糖尿病伴面神经麻痹15例临床分析

目的 探讨糖尿病伴发面神经麻痹的临床特点,以强化对该病的认识.方法 对15例糖尿病伴发面神经麻痹的临床资料进行分析.结果 15例2型糖尿病患者右侧周围性面瘫9例,左侧周围性面瘫6例;15例均出现患侧额纹变浅,眼睑闭合不全,鼻唇沟变浅,鼓腮漏气,口角偏向健侧,无味觉障碍,无听觉过敏;经控制血糖,促神经修复,活血化瘀,改善循环等治疗后均痊愈.结论 2型糖尿病伴发面神经麻痹多呈单侧不完全性周围性面神经麻痹,及时诊治,预后良好.     

盐酸纳洛酮配合星状神经节阻滞治疗神经性耳聋的疗效观察

目的观察纳洛酮配合星状神经节阻滞治疗神经性耳聋的疗效。方法神经性耳聋患者68例,随机分为2组,每组34例。A组采用纳洛酮配和星状神经节阻滞治疗;B组为对照组,用常规治疗。结果2组病例治疗后耳聋症状均有改善。A组与B组相比较,有效率显著提高（P〈0．05）。结论纳洛酮配合星状神经节阻滞治疗神经性耳聋的疗效令人满意。     

椎旁神经阻滞治疗颈源性头痛对比观察

目的 探讨椎旁神经阻滞治疗颈源性头痛的临床疗效.方法 76例颈源性头痛患者随机分为椎旁神经阻滞联合星状神经节阻滞(A组)和星状神经节阻滞(B组),每组38例.星状神经节阻滞1次/2 d,5次一个疗程;椎旁神经阻滞1次/5 d,3次一个疗程.结果 A、B两组治疗后显效率分别为89.4%和68.4%,两组疗效比较有显著性差...     

星状神经节阻滞配合穴位阻滞治疗偏头痛：附56例疗效观察

采用星状神经节能阻滞配合穴位阻滞治疗偏头痛５６例，结果治愈４２例，显效１２酌，无效２例，总有效率９６．４３％。明显优于单纯星状神经节阻滞，对长期服药效果不佳的顽固性头痛仍有明显疗效，说明该疗法治疗偏头痛疗效显著，值得在临床推广。     

Ramsy-Hunt''''s综合征合并多颅神经脑膜炎1例报道

我们经治一病例,因头痛,耳道疱疹,耳痛,面瘫,合并有听力减退,前庭功能障碍,轻度面部感觉障碍,及悬雍垂偏斜,声音嘶哑,入院治疗。腰穿白细胞数达到30mm3个。经用抗疱疹病毒药物,抗炎,激素,对症治疗近一个月,症状见缓解,CSF细胞数为0后出院。出入院诊断Ramsy—Hunt’s综合征合并多颅神经,脑膜炎。Ramsy-Hunt’s综合征又称带状疱疹神经节综合征,系面神经膝状神经节的疱疹性炎症所引起的一组病症。轻型,Ⅰ型无散明显神经系统症状发现,Ⅱ型伴同侧周围性面神经麻痹,重者Ⅲ型为疱疹合并面瘫及听力     

星状神经节阻滞配合穴位阻滞治疗偏头痛(附56例疗效观察)

采用星状神经节阻滞配合穴位阻滞治疗偏头痛56例,结果治愈42例（75％）;显效12例（21．43％）;无效2例,总有效率96．43％。明显优于单纯星状神经节阻滞（总有效率84％P＜0．05）及单纯穴位阻滞（总有效率80％,P＜0．05）,对长期服药效果不佳的顽固性头痛仍有明显疗效,说明该疗法治疗偏头痛疗效显著,值得在临床推广。     

星状神经节阻滞治疗偏头痛临床观察

目的观察星状神经节阻滞治疗偏头痛的临床疗效。方法随机选择64例偏头痛患者,应用0.9%氯化钠注射夜、2%利多卡因及曲安奈德注射液行双侧星状神经节交替阻滞,隔天一次,10d一疗程,共3个疗程。结果Ⅰ级完全缓解（优）42例,治愈率65.6%;Ⅱ级好转（良）14例,好转率21.9%;Ⅲ级有效（一般）6例,有效率9.4%;Ⅳ级无效2例,无效率3.1%。结论星状神经节阻滞治疗偏头痛临床疗效确切。     

针灸治疗老年周围性面瘫的疗效分析

目的 探讨针灸治疗老年急性期周围性面瘫的临床效果。方法 2017年4月至2019年2月收治老年急性期周围性面瘫96例,其中48例采用针灸治疗（观察组）,48例采用常规治疗（对照组）。对照组病人给予常规药物口服联合康复训练,观察组病人在对照组治疗基础上联合使用针灸治疗。结果 治疗后,两组House-Brackmann评分、Sunnybrook评分、躯体功能评分、社会功能评分、面神经潜伏期、面神经波幅均明显改善（P<0.05）,而且,观察组明显优于对照组（P<0.05）。观察组有效率（97.97%,47/48）明显高于对照组（83.33%,41/48;P<0.05）。结论 针灸治疗老年周围性面瘫,疗效显著,能够促进病人面神经功能恢复,改善临床症状     

Stellate ganglion block reduces inflammation and improves neurological function in diabetic rats during ischemic stroke

Diabetes mellitus is an independent risk factor for ischemic stroke.Both diabetes mellitus and stroke are linked to systemic inflammation that aggravates patient outcomes.Stellate ganglion block can effectively regulate the inflammatory response.Therefore,it is hypothesized that stellate ganglion block could be a potential therapy for ischemic stroke in diabetic subjects.In this study,we induced diabetes mellitus in rats by feeding them a high-fat diet for 4 successive weeks.The left middle cerebral artery was occluded to establish models of ischemic stroke in diabetic rats.Subsequently,we performed left stellate ganglion block with 1%lidocaine using the percutaneous posterior approach 15 minutes before reperfusion and again 20 and 44 hours after reperfusion.Our results showed that stellate ganglion block did not decrease the blood glucose level in diabetic rats with diabetes mellitus but did reduce the cerebral infarct volume and the cerebral water content.It also improved the recovery of neurological function,increased 28-day survival rate,inhibited Toll like receptor 4/nuclear factor kappa B signaling pathway and reduced inflammatory response in the plasma of rats.However,injection of Toll like receptor 4 agonist lipopolysaccharide 5 minutes before stellate ganglion block inhibited the effect of stellate ganglion block,whereas injection of Toll like receptor 4 inhibitor TAK242 had no such effect.We also found that stellate ganglion block performed at night had no positive effect on diabetic ischemic stroke.These findings suggest that stellate ganglion block is a potential therapy for diabetic ischemic stroke and that it may be mediated through the Toll like receptor 4/nuclear factor kappa B signaling pathway.We also found that the therapeutic effect of stellate ganglion block is affected by circadian rhythm.     

Stellate ganglion block therapy against progressive facial hemiatrophy

A typical case with progressive facial hemiatrophy was treated with a new therapeutic trial, stellate ganglion block. The present case, a Japanese girl, suffered from progressive atrophy involving the soft tissue of the left buccal region, with onset at the age of 6 following a minor local trauma. She visited our hospital at the age of 9, and as soon as the diagnosis was made, left stellate ganglion block was initiated. Local injection of lidocaine was performed 53 times over the period of 1 year and 4 months. During this period of therapy and the subsequent follow-up period of 4 years, the state of atrophy remained unchanged and nonprogressive. Stellate ganglion block as a therapy against progressive facial hemiatrophy was considered to be worth further evaluation, although it was impossible to judge, based solely on our experience, whether the arrest of progression was attributable to the therapy. The rationale of this therapy was also discussed. It was based upon the assumption that atrophy may result from irritation of the cervical sympathetic nerve, one of the most popular theories regarding the pathomechanism of progressive facial hemiatrophy.     

肌内效贴贴扎疗法治疗周围性面瘫的临床效果

目的研究肌内效贴贴扎疗法治疗周围性面瘫的临床效果。方法选取2013-09—2016-09于我院接受治疗的60例周围性面瘫患者为研究对象,按照入院顺序分为对照组与观察组各30例。对照组给予常规物理康复联合西药治疗,观察组在此基础上给予肌内效贴贴扎疗法,观察2组临床效果。结果治疗后,观察组评分提升至(16.83±3.14)分,明显高于对照组的(12.11±2.18)分,差异有统计学意义(P0.05);观察组总有效率为93.33%,明显高于对照组的70.00%。结论在周围性面瘫患者的临床治疗中,应用肌内效贴贴扎疗法,可缓解患者脸部疼痛感,促进肌肉力量的恢复,改善患者的临床症状,疗效显著,值得推广。     

小儿周围性面神经麻痹的临床分析

目的探讨小儿周围性面神经麻痹的病因、临床特点及治疗方法。方法回顾性分析2000—2009年周围性面神经麻痹患儿8例,8例患儿头颈部影像学检查均为阴性,8例患儿均接受糖皮质激素和营养神经药物治疗。结果经过3个月的随访,8例患儿均治愈且无复发。结论小儿周围性面神经麻痹病因与临床表现常不典型,糖皮质激素治疗具有很好的疗效。     

丁咯地尔与肌氨肽苷联合治疗糖尿病周围神经病疗效观察

目的:观察丁咯地尔与肌氨肽苷联合治疗糖尿病周围神经病变的疗效。方法:86例患者随机分为治疗组和对照组各43例。治疗组:在常规治疗基础上应用丁咯地尔150mg加入生理盐水250ml、肌氨肽苷8ml加入生理盐水250ml中静脉滴注,每日一次;对照组:在常规治疗基础上维生素B1100mg、维生素B12500μg肌肉注射,每日一次。连续治疗4周。结果:治疗组:显效29例,有效9例,无效5例;总有效率88.3%,明显高于对照组的62.8%,经秩和检验P<0.01,且未见明显副作用。结论:丁咯地尔与肌氨肽苷联合治疗糖尿病周围神经病变是较理想的药物。     

尼莫地平治疗糖尿病周围神经病变的临床研究

目的观察尼莫地平对糖尿病周围神经病变患者肌电图及血液流变学的影响。方法将71例糖尿病周围神经病变患者随机分为两组,对照组30例予以传统的治疗,治疗组41例在此基础上加用尼莫地平口服治疗;观察尼莫地平对肌电图及血液流变学的影响。结果经尼莫地平治疗6个月后,治疗组的神经症状、体征及正中神经、胫神经MCV和SCV的改善极显著(P<0.01),对血液流变学指标有明显改善(P<0.05),均优于对照组。结论尼莫地平治疗糖尿病周围神经病变有较好疗效。     

Mouse model of Bell's palsy induced by reactivation of herpes simplex virus type 1

In order to investigate the mechanism of Bell's palsy, we developed an animal model of facial nerve paralysis induced by the reactivation of herpes simplex virus type 1 (HSV-1). Eight weeks after recovery from facial nerve paralysis caused by inoculation with HSV-1, the mice were treated with auricular skin scratch at the site of the previous inoculation, or with intraperitoneal injection of anti-CD3 monoclonal antibody (mAb), or combination of both procedures. No mice developed facial nerve paralysis when they were treated with either auricular scratch or mAb injection alone. In contrast, 20% of mice developed facial nerve paralysis with the combined treatment. With one exception, no mouse treated with either auricular scratch or mAb injection showed HSV-I DNA in their facial nerve tissue, whereas 4 out of 6 mice receiving both treatments showed HSV-1 DNA on day 10 after treatment. Histopathological findings showed neuronal degeneration in the geniculate ganglion and demyelination of the facial motor nerve in paralyzed mice. These findings suggest that a combination of stimuli, local skin irritation, and general immunosuppression is essential for successfully inducing facial nerve paralysis in mice with latent HSV-1 infection.     

颅脑外伤中颈性眩晕的早期治疗研究

目的 探讨轻、中型颅脑外伤中颈性眩晕患者的早期治疗方案.方法 将轻、中型颅脑外伤中颈性眩晕患者84例按随机数字表法分成治疗组(38例)与对照组(46例),治疗组采用颈椎牵引、星状神经节封闭、早期颈部理疗等方法 并结合药物治疗,对照组采用单纯药物治疗,对其疗效进行非参数秩和检验分析.结果 治疗组治愈29例,好转8例,无效1例,平均治疗时间20d;对照组治愈26例,好转15例,无效5例,平均治疗时间30 d;治疗组疗效优于对照组,差异有统计学意义(P＜0.05).结论对颅脑外伤中颈性眩晕患者早期采用针对性治疗,其疗效好于单纯药物治疗,且治疗时间缩短.     

经皮神经电刺激对急性面瘫患者神经恢复的影响

目的探讨经皮神经电刺激联合药物治疗对急性面瘫患者神经恢复的影响。方法济源市中医院2015-04-2017-06收治的124例急性面瘫患者为研究对象,采用经皮神经电刺激联合药物治疗的66例患者为观察组,常规治疗的58例患者为对照组,治疗2周后评价2组患者的临床症状及面神经功能。结果治疗后观察组额纹消失、鼻唇沟消失及鼓腮漏气患者相比治疗前明显减少(P0.05),对照组仅鼓腮漏气患者较治疗前明显减少(P0.05);组间比较治疗后观察组额纹消失、眼睑闭合露白及鼓腮漏气患者均较对照组明显减少(P0.05);治疗后观察组面神经功能分级人数分布与对照组相比差异具有统计学意义(P0.05)。结论经皮神经电刺激可在常规治疗的基础上有效改善面神经功能的恢复,进而提高其临床治疗效果。