缺碘地区7—14岁儿童亚临床克汀病的流行趋势

缺碘地区供应碘盐后，重度缺碘地区亚克汀病患病率呈下降趋势，轻度缺碘地区各年龄组与对照组比较差异无显著意义（Ｐ〉０．０５）。缺碘地区儿童智商明显低于对照组（Ｐ〈０．０１），低年龄组智商高于本地区高年龄组（Ｐ〈０．０５），但与对照组同年龄比较仍有显著差别（Ｐ〈０．０５）。     

碘缺乏病病区轻度智力落后儿童精神运动测验结果评价

目的　验证津医精神运动成套测验（ＪＰＢ）检查轻度智力落后儿童精神运动障碍的灵敏度,评估碘缺乏病（ＩＤＤ）病区亚克汀病患病率。方法　对中国联合型瑞文测验智商常模（ＣＲＴ－Ｃ２）判定的４１５ 名７～１４ 岁轻度智力落后儿童进行ＪＰＢ检查,用Ｔ 分数与损伤指数确定其精神运动功能状况。结果　Ｔ 分数确定的ＪＰＢ检出ＩＤＤ 重、中病区ＩＱ ５０～６９ 儿童精神运动功能异常率为５７．８％ ,其中ＩＱ ５０～５９ 人群异常率达７０．９％ ;损伤指数确定的异常率与Ｔ 分结果差异不显著（ Ｐ＞ ０．０５）。结论　ＪＰＢ是发现和定量描述轻度智力落后儿童精神运动功能障碍的有效实用方法,可用于诊断亚克汀病。     

高压氧治疗新生儿缺氧缺血性脑病78例疗效观察

对７８例新生儿缺氧缺血性脑病（ＨＩＥ）给予高压氧加综合治疗,存活病例随访至１～４岁。采用国内ＣＤＣＣ量表测定智商及神经系统检查,复查头颅ＣＴ。对照组６２例,仅给综合治疗。结果发现：高压氧组中、重度ＨＩＥ患儿神经症状消失平均时间短于对照组（Ｐ〈０．０１）;两组总有效率比较,有显著性差异（Ｐ〈０．０１）。早期高压氧治疗发生脑损害较对照组明显减少（Ｐ〈０．０１）,预后不良率低于对照组（Ｐ〈０．０１）;晚     

巨人脑黄金对弱智儿童学习记忆的临床观察

目的：观察巨人脑黄金对弱智儿童学习记忆的改善作用。方法：将 ７０ 例弱智儿童分成实验组和对照组，每组３５ 人，用韦氏记忆量表对他们进行 ４ 个月的记忆能力观察。结果：实验组 ３５ 例弱智儿童服用巨人脑黄金后，长时记忆由２８．１７±３．１４ 上升至 ３０．２０±４．５４（ Ｐ＜ ０．０５）、短时记忆由４７．６５ 上升至 ５１．６５±５．４０（ Ｐ＜ ０．０１）、瞬时记忆由 ６．６０±１．８８ 上升至 ７．９４±１．３０（ Ｐ＜ ０．０１）、记忆商由 ７４．００±８．００上升至 ８０．５７±９．７４（ Ｐ＜ ０．０１）；对照组前后对比差异无显著性。结论：给弱智儿童服用巨人脑黄金，可明显提高记忆能力。     

济南市学龄儿童智力水平调查研究

本文报告应用瑞文测验（ＣＲＴ－ＲＣ）中国农村版和城市智商常模对济南市区学龄儿童的智商进行了测试，结果表明：济南市儿童智商基本呈正常分布，略向高值偏移。儿童的智商除受碘元素影响外，也与学生的生活营养水平和父母的文化程度有关，且不同年龄、性别和不同测试时间儿童的智商水平无显著性差异（Ｐ〉０．０５），但智商与学生的学习成绩明显相关（Ｐ〈０．０１），智商与数学的相关系数大于与语文的相关系数，说明ＣＲＴ－Ｒ     

糖尿高见我膜恙与血小板体积关系

测定１００例Ⅱ型糖尿病患平均血小板体积（ＭＰＶ）、血小板压积（ＰＧＴ）,血小板分布宽度（ＰＤＷ）,血小板计数（ＰＬＴ）,并与５０例健康人比较,发现Ⅱ型糖尿病平均ＭＰＬ、ＰＬＴ、ＰＤＷ高于对照组（Ｐ〈０．０５）,说明Ⅱ型糖尿病存在血小板功能异常。比较有视网膜病变与无视网膜病变且与对照组之间关系,示均有显性差异（Ｐ〈０．０５）,而以有视网膜病变组差异更为显（Ｐ〈０．０１）,说明血小板功能异常在视     

农村非IDD病区智力正常儿童精神运动成套测验的检测结？…

目的：掌握非ＩＤＤ病区智力正常儿童精神运动成套测验的正常值，为制定全国儿童精神运动测验量表提供依据。方法：按“九五”国家医学科技攻关项目的设计，在沿海和内陆平原家村非ＩＤＤ病区对ＩＱ８０￣１１９的无甲肿７￣１４岁儿童进行１０项精神运动测验。结果：选择反应时测验的反应时间（ｍｓ）间隔均值是由于小年龄组向大年龄组逐渐递降，相临两个年龄组差异显（Ｐ〈０．０１或Ｐ〈０．０５）；连续作业、划消数字、目标追     

长期应用地塞米松、复方氨基比林退热儿童的T、B细胞免疫功能变化

应用流式细胞免疫学方法对６２例长期单纯使用地塞米松（ＤＸＳ）和复方氨基比林（ＡＭＣ）退热儿童进行Ｔ淋巴细胞亚群、Ｂ淋巴细胞及活化Ｂ淋巴细胞检测。结果表明：此类儿童的Ｔ细胞总数明显降低（Ｐ〈０．０５）,尤以ＣＤ４下降明显（Ｐ〈０．０１）,ＣＤ８细胞数轻度下降（Ｐ〉０．０５）,Ｂ淋巴细胞及活化Ｂ淋巴细胞数明显下降（Ｐ〈０．０５）。本文提示,长期单纯使用ＤＸＳ及ＡＭＣ退热可致儿童免疫功能明显下降,且与作     

IDD病区儿童智力与微量元素关系的研究

本文对ＩＤＤ病区不同智商的儿童发中铜、锌、锰、锂作了分析，结果显示，病区智低组儿童发中铜、锌、锰、锂均高于中等智商组，病区与非病区智低组比较。两组猛含量有显著性差异（Ｐ〈０．０２５），病区高于非病区；病区组锂显著低于非病区（Ｐ〈０．０５），中等智力组仅病区儿童发锂显著低于非病区（Ｐ〈０．０５），其余元素无显著差异。     

氧化型和正常极低密度脂蛋白对猪主动脉平滑肌细胞脂类堆积的不同影响

为了观察氧化型及正常极低密度脂蛋白对血管平滑肌细胞内脂类堆积的不同影响，探索平滑肌细胞摄取氧化型极低密度脂蛋白的受体途径，用２００ｍｇ／Ｌ的氧化型及正常极低密度脂蛋白与猪主动脉平滑肌细胞温有４８ｈ后，细胞内甘油三脂含量分别为对照组的３．２倍和１０．６倍（Ｐ〈０．０１），且两个实验组之间相比，差异也有显著性意义（Ｐ〈０．０１），细胞内总胆固醇明显升高（Ｐ〈０．０５），但是两个实验组之间无显著差异（Ｐ     

Obesity in children

The prevalence of childhood obesity has increased dramatically during the past decades all over the world. The majority of obesity in adulthood has its origins in childhood which makes obesity a pediatric concern and the period when interventions should be done. Obesity is associated with increased morbidity and mortality in adult life and several adverse consequences in childhood like insulin resistance, type 2 diabetes, dyslipidemia, polycystic ovarian syndrome, pulmonary and orthopedic disorders and psychological problems. Both genetic and environmental factors play a role in the development of obesity. Prevention of obesity is critical, since effective treatment of this disease is limited. Food management and increased physical activity must be encouraged, promoted, and prioritized to protect children.     

Thrombolysis in children

Thrombosis in children may result in vascular occlusion and a potential loss of viability in skin, limbs or organs, or lead to the development of post thrombotic syndrome. Thrombolysis may prevent such complications, and the use of thrombolytics in children has increased in the last three decades. Despite this, optimum paediatric treatment regimens for these drugs remain uncertain, and accurate efficacy and safety profiles for thrombolytics are limited by the lack of controlled, prospective studies in well-defined patient populations. Restoration of vessel patency has often been achieved but the risk of intracranial and other major haemorrhage secondary to thrombolysis continues to be a significant concern for the clinician deciding on such treatment. This review summarises the use of thrombolytic treatment in children and describes outcome data and adverse events following treatment, as well as the limitations of published studies on paediatric thrombolysis.     

Tuberculosis in children

Tuberculosis (TB) control poses one of the major global health challenges in the new millennium. Children in TB-endemic areas suffer severe TB related morbidity and mortality, despite the availability of cheap and effective TB treatment. However, providing an accurate TB diagnosis together with access to supervised, child friendly treatment remains difficult in resource-limited settings. This review provides a broad overview of recent advances related to child TB, focusing on intra-thoracic disease manifestations. It summarizes current understanding of TB epidemiology, disease prevention, diagnosis and treatment, but also introduces novel concepts for further discussion and future evaluation.