Play Interactions of Family Members Towards Children with Autism

The play interactions of family members towards children with autism were examined in the current study. Siblings, mothers, and fathers of nine families of a child with autism were observed in dyadic play interactions with the child. Results revealed that mothers and fathers exhibited more play behaviors towards children with autism than siblings, while the children with autism initiated more interactions towards siblings than towards parents. Vineland scale scores were correlated with parental behaviors and the initiations of children with autism towards parents. Results suggest that parents may compensate for their child's disability level by initiating more play interactions. Implications include teaching parents how to pace play interactions to allow children with autism to initiate play interactions.     

Feeding and Eating Behaviors in Children with Autism and Typically Developing Children

Mothers of children aged 2–12 years completed an exhaustive questionnaire assessing feeding and eating behaviors for both themselves and their children with autism, and typically developing siblings of children with Autism Spectrum Disorder (where available), or typically developing children with no sibling with a disability. Results indicate that children with autism were only marginally more likely to exhibit picky eating behavior (overall style) than their siblings or matched typically developing children. Rates of ritualistic feeding behaviors were equivalent in all groups of children although children with autism were more likely to be currently exhibiting problematic eating and feeding behaviors. The implications of these results for the treatment of feeding difficulties exhibited by children with autism will be discussed.

Brief Report: Circumscribed Attention in Young Children with Autism

School-aged children and adolescents with autism demonstrate circumscribed attentional patterns to nonsocial aspects of complex visual arrays (Sasson et al. 2008). The current study downward extended these findings to a sample of 2–5 year-olds with autism and 2–5 year-old typically developing children. Eye-tracking was used to quantify discrete aspects of visual attention to picture arrays containing combinations of social pictures, pictures of objects frequently involved in circumscribed interests in persons with autism (e.g., trains), and pictures of more commonplace objects (e.g., clothing). The children with autism exhibited greater exploration and perseverative attention on objects related to circumscribed interests than did typically developing children. Results suggest that circumscribed attention may be an early emerging characteristic of autism.     

Linking Parental Perceptions to Interactions in Young Children with Autism

This study examines the relation of parental perceptions and observed parent–child interactive behaviors. Samples observed included normally developing children, children with autism, and children with mental retardation who were equivalent on mental age. Parental perceptions of children's temperament and parental feelings of parenting stress were examined. Results indicated that parental perceptions of autistic children's behavior were more often linked to actual child and parental behaviors than in the comparison samples. Parents who reported their autistic children as more difficult in temperamental style had children who were less engaged during a social game with the parent and less responsive in interaction with an experimenter. Parents who reported greater stress had autistic children who were less responsive in social interactions with others.     

Social Perception in Children with Autism: An Attentional Deficit?

Research suggests that the attentional deficits found in children with autism may be related to impairments in social functioning (e.g., Courchesne et al., 1994a, 1994b; Lewy & Dawson, 1992; Schreibman & Lovaas, 1973). In the present investigation, 14 children with autism, 14 mentally handicapped, and 14 typically functioning children participated in a study designed to investigate the effects of number of social cues on the ability to interpret social situations. Participants were shown videotaped vignettes of child–child interactions in which the number of cues leading to the correct interpretation of the story varied from one to four (i.e., tone, content, nonverbal, or nonverbal with object). Subjects were then asked a series of questions which varied in degree of complexity. Overall, results indicated that children with autism performed as well as both groups of comparison subjects on general attention questions (i.e., identification of number and gender of interactants) and social perception questions relating to stories containing one cue. However, children with autism performed more poorly than both comparison groups on social perception questions relating to stories containing multiple cues. Results are discussed in terms of an attentional dysfunction hypothesis of autism.     

The Effect of Therapeutic Horseback Riding on Social Functioning in Children with Autism

This study evaluated the effects of therapeutic horseback riding on social functioning in children with autism. We hypothesized that participants in the experimental condition (n = 19), compared to those on the wait-list control (n = 15), would demonstrate significant improvement in social functioning following a 12-weeks horseback riding intervention. Autistic children exposed to therapeutic horseback riding exhibited greater sensory seeking, sensory sensitivity, social motivation, and less inattention, distractibility, and sedentary behaviors. The results provide evidence that therapeutic horseback riding may be a viable therapeutic option in treating children with autism spectrum disorders.     

Recess is Time-in: Using Peers to Improve Social Skills of Children with Autism

Children with autism face enormous struggles when attempting to interact with their typically developing peers. More children are educated in integrated settings; however, play skills usually need to be explicitly taught, and play environments must be carefully prepared to support effective social interactions. This study incorporated the motivational techniques of Pivotal Response Training through peer-mediated practice to improve social interactions for children with autism during recess activities. A multiple baseline design across subjects was used to assess social skills gains in two elementary school children. The results demonstrated an increase in important social skills, namely social initiations and turn taking, during recess.     

When Asking Questions is Not Enough: An Observational Study of Social Communication Differences in High Functioning Children with Autism

This investigation examined communication patterns between high functioning children with autism and their families and typically developing children and their families within traditional dinner time conversation. Twenty families with a child with autism (3.5–7 years.) and ten families with typically developing children (3.5–6 years) were video recorded during dinner and their interactions were coded. Results revealed that children with autism initiated fewer bids for interactions, commented less often, continued ongoing interactions through fewer conversational turns, and responded less often to family member communication bids. Results are interpreted with respect to how communication patterns may be indicative of social communication deficits not previously examined in high functioning children with autism. Strategies for social communication interventions within the family and other natural contexts are discussed.     

Plasma Oxytocin in Children with Autism and Its Correlations with Behavioral Parameters in Children and Parents

Objective

Oxytocin (OT) has been implicated to play an important role in autism spectrum disorders (ASD) etiology. We aimed to find out the differences in plasma OT levels between children with autism and healthy children, the associations of OT levels with particular autism symptoms and the associations of particular parental autistic traits with their ASD children OT levels.

Methods

We included 19 boys with autism and 44 healthy age-matched boys. OT levels were analyzed by ELISA method. Children with autism were scored by Childhood Autism Rating Scale and Autism Diagnostic Interview (ADI), adjusted research version. Autism Spectrum Quotient (AQ), Systemizing Quotient (SQ) and Empathizing Quotient were completed by parents of children with autism.

Results

Children with autism had significantly lower plasma OT levels than controls. OT levels positively correlated with ADI Reciprocal Interaction and Communication scores. AQ and SQ of fathers positively correlated with children plasma OT level.

Conclusion

Our results support the hypothesis of OT deficiency in autism. The "paradoxical" associations of OT levels and social skills in children with autism indicate disturbances at various levels of OT system. We first reported associations of OT levels in children with autism and behavioral measures in fathers indicating that OT abnormalities stay between parental autistic traits and autism symptoms in their children.     

The effect of context on imitation skills in children with autism

Children with autism exhibit deficits in imitation skills. Previous authors have suggested that they may have particular difficulty imitating in natural social interactions, but properly controlled experiments investigating this possibility have not been conducted. To investigate this possibility, children with autism and typically developing children were compared on a series of imitation tasks presented either in a structured-elicited or naturalistic-spontaneous condition. Modeled actions were counterbalanced across conditions. Results suggest children with autism imitated less than typically developing children overall; however, this difference was mainly evident when the imitation task was presented in a spontaneous context. In addition, they exhibited less coordinated joint attention during imitation than the typically developing children. These findings support the hypothesis that children with autism are particularly impaired in their ability to imitate spontaneously.     

Increased Eye Contact During Conversation Compared to Play in Children With Autism

Children with autism have atypical gaze behavior but it is unknown whether gaze differs during distinct types of reciprocal interactions. Typically developing children (N?=?20) and children with autism (N?=?20) (4–13 years) made similar amounts of eye contact with an examiner during a conversation. Surprisingly, there was minimal eye contact during interactive play in both groups. Gaze behavior was stable across 8 weeks in children with autism (N?=?15). Lastly, gaze behavior during conversation but not play was associated with autism social affect severity scores (ADOS CSS SA) and the Social Responsiveness Scale (SRS-2). Together findings suggests that eye contact in typical and atypical development is influenced by subtle changes in context, which has implications for optimizing assessments of social communication skills.     

Children with high-functioning autism and Asperger's syndrome: Can we differentiate their cognitive profiles?

The aim of this study was to investigate whether children with high-functioning autism (HFA) and Asperger's syndrome (AS) can be differentiated from each other and from typically developing children on their cognitive profiles. The present study included a total of 45 participants: children with autism (high-functioning autism or Asperger's syndrome) and a matched control group of typically developing children (n = 15 per group). Two tasks were used to establish their cognitive profiles: the Wechsler Intelligence Scale for Children-Third Edition (WISC-III) and the NEPSY scale. Our results highlighted differentiated profiles between the children with Asperger's syndrome and those with high-functioning autism. The first ones showed strengths on verbally mediated skills as well as weaknesses on visual-motor coordination and graphomotor ability, whereas the children with HFA exhibited a profile with deficits on tasks calling upon verbal comprehension and good performances on tasks requiring visuo-spatial skills. This paper argues for a revision of AS criteria in the forthcoming DSM-V rather than a combination of the two subgroups within the autism spectrum disorders in the diagnostic manual.     

Improving Social Initiations in Young Children with Autism Using Reinforcers with Embedded Social Interactions

Children with autism often exhibit low levels of social engagement, decreased levels of eye contact, and low social affect. However, both the literature and our direct clinical observations suggest that some components of intervention procedures may result in improvement in child-initiated social areas. Using an ABAB research design with three children with autism, this study systematically assessed whether embedding social interactions into reinforcers, delivered during language intervention, would lead to increased levels of child-initiated social behaviors. We compared this condition with a language intervention condition that did not embed social interactions into the reinforcers. Results indicated that embedding social interactions into the reinforcers resulted in increases in child-initiated social engagement during communication, improved nonverbal dyadic orienting, and improvements in general child affect. Theoretical and applied implications are discussed.     

Responses and sustained interactions in children with mental retardation and autism

Sustained interactions and responses to social bids made by children with autism and verbal-age–matched children with mental retardation were recorded in two naturalistic settings. Children with autism produced fewer positive responses and more no responses than children with mental retardation; both groups were more likely to make positive responses to adults and not to respond to other children. Furthermore, although the frequency of conversations was not different for the two groups, children with autism were significantly less likely to engage in sustained play compared to children with mental retardation. Results suggest that children with autism are able to master the more rote and need-oriented social skills, such as simple conversation, but may not develop other forms of social interactions, like play.     

Autonomic Arousal Response Habituation to Social Stimuli Among Children with Asd

Sustained autonomic arousal during eye contact could cause the impairments in eye contact behavior commonly seen in autism. The aim of the present study was to re-analyze the data from a study by Kaartinen et al. (J Autism Develop Disord 42(9):1917–1927, 2012) to investigate the habituation of autonomic arousal responses to repeated facial stimuli and the correlations between response habituation and social impairments among children with and without ASD. The results showed that among children with ASD, the smaller the habituation was, specifically in responses to a direct gaze, the more the child showed social impairments. The results imply that decreased autonomic arousal habituation to a direct gaze might play a role in the development of social impairments in autism.     

Peer Interaction and Loneliness in High-Functioning Children with Autism

Social interaction with peers and the understanding and feelings of loneliness were examined in 18 high-functioning children with autism and 17 typically developing children matched for IQ, chronological age, gender, and maternal education. Observations were conducted on children's spontaneous social initiations and responses to their peers in natural settings such as recess and snack time, and children reported on their understanding and feelings of loneliness and social interaction. Overall, children with autism revealed a good understanding of both social interaction and loneliness, and they demonstrated a high level of social initiation. However, they spent only half the time in social interactions with peers compared with their matched counterparts, and they interacted more often with a typically developing child than with another special education child. Despite the intergroup differences in frequency of interaction, a similar distribution of interactions emerged for both groups, who presented mostly positive social behaviors, fewer low-level behaviors, and very infrequent negative behaviors. Children with autism reported higher degrees of loneliness than their typical age-mates, as well as a lower association between social interaction and loneliness, suggesting their poorer understanding of the relations between loneliness and social interaction. Research and practice implications of these findings are discussed.     

How Young Children Treat Objects and People: An Empirical Study of the First Year of Life in Autism

Objective. To figure out features of autism before the age of one and to explore the pathways of early social and nonsocial attention in autism through home movies.Method. Home movies of 15 children later diagnosed with autism, are compared with home movies of 13 typical children. The films of the two groups have been mixed and rated by blind observers through a Grid composed of social and nonsocial item and applied to two age ranges: 0–6 months (T1) and 7–12 months (T2). Two MANOVAs, an ANOVA and discriminant analyses were applied.Results. Significant differences between the two groups were found only for the item in the Social area at T1 but not at T2, when groups did not differ in either social or nonsocial areas. At T2 children with autism had significantly higher scores in the nonsocial area while normal children did not show significant differences between areas. Discriminant analyses revealed that social attention can distinguish the two groups at T1 but not at T2.Conclusions. The fundamental impairment of joint attention in autism could be considered a consequence of the early atypical developmental gap and of a later disconnection between attention to people and objects. Abnormal developmental trajectories for social and nonsocial attention could help us in the future to understand relationships between adaptive capacities and symptoms, and set the stage for appropriate early screening instruments.This study was supported by grant RC 6/02 from National Institute of Health.     

Evidence that genetic variation in the oxytocin receptor (OXTR) gene influences social cognition in ADHD

Some children with ADHD also have social and communication difficulties similar to those seen in children with autistic spectrum disorders and this may be due to shared genetic liability. As the oxytocin receptor (OXTR) gene has been implicated in social cognition and autistic spectrum disorders, this study investigated whether OXTR polymorphisms previously implicated in autism were associated with ADHD and whether they influenced OXTR mRNA expression in 27 normal human amygdala brain samples. The family-based association sample consisted of 450 DSM-IV diagnosed ADHD probands and their parents. Although there was no association with the ADHD phenotype, an association with social cognitive impairments in a subset of the ADHD probands (N = 112) was found for SNP rs53576 (F = 5.24, p = 0.007) with post-hoc tests demonstrating that the AA genotype was associated with better social ability compared to the AG genotype. Additionally, significant association was also found for rs13316193 (F = 3.09, p = 0.05) with post-hoc tests demonstrating that the CC genotype was significantly associated with poorer social ability than the TT genotype. No significant association between genotype and OXTR mRNA expression was found. This study supports previous evidence that the OXTR gene is implicated in social cognition.     

Benchmarks of Social Treatment for Children with Autism

Data on the social behavior of typical children may inform practitioners and researchers regarding the appropriate goals of intervention for children with autism. This study assessed the ongoing levels of naturally occurring social behavior in 64 preschool-aged children. A 2 × 2 factorial design was used to analyze population (children with autism and typical children) and age (3 years 3 months vs. 4 years 4 months) differences at the time of preschool entry. Predictable population differences were found for key social behaviors of proximity to children, social bids from children, and focus of engagement on children, as well as for behavioral context variables of verbalizations, adult focus, and atypical behaviors. No differences were found in the amount of time spent focused on toys or objects. There were also no differences in the presenting behaviors of younger and older children with autism. Results are discussed in terms of implications for establishing early social intervention goals.     

Children with Autism Fail to Orient to Naturally Occurring Social Stimuli

Children with autism were compared to developmentally matched children with Down syndrome or typical development in terms of their ability to visually orient to two social stimuli (name called, hands clapping) and two nonsocial stimuli (rattle, musical jack-in-the-box), and in terms of their ability to share attention (following another's gaze or point). It was found that, compared to children with Down syndrome or typical development, children with autism more frequently failed to orient to all stimuli, and that this failure was much more extreme for social stimuli. Children with autism who oriented to social stimuli took longer to do so compared to the other two groups of children. Children with autism also exhibited impairments in shared attention. Moreover, for both children with autism and Down syndrome, correlational analyses revealed a relation between shared attention performance and the ability to orient to social stimuli, but no relation between shared attention performance and the ability to orient to nonsocial stimuli. Results suggest that social orienting impairments may contribute to difficulties in shared attention found in autism.