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1.
《中国实用乡村医生杂志》2004,11(12):45
一、选择题
1.E 2.E 3.A 4.A 5.C 6.C 7.C 8.C9.B 10.B 11.A 12.A 13.A 14.E 15.D 16.D17.B 18.D 19.A 20.D 21.D22.D 23.C 24.A25.D 26.D 27.A 28.B29.C 30. 31.C 32.D33.D 34.E 35.D
…… 相似文献
2.
《中国妇幼保健》2019,(2)
目的探讨头孢菌素联合青霉素对感染性肺炎新生儿血清炎性因子及肠道微生态环境的影响。方法选取2014年9月-2015年8月收治的90例感染性肺炎新生儿为研究对象,根据入院时间按照病历号随机分为头孢菌素组、青霉素组、头孢菌素联合青霉素组(联合组)各30例,分别给予头孢菌素、青霉素、头孢菌素联合青霉素治疗,治疗时间均为1周,比较3组感染性肺炎新生儿临床症状改善时间、血清炎性因子、肠道微生态环境、临床疗效等指标,同时选择35例正常未使用抗生素治疗的新生儿作为对照组。结果 3组治愈率比较,差异无统计学意义(84. 85%vs. 78. 79%vs. 81. 82%)(χ2=0. 987,P0. 05);联合组感染性新生儿发热、气促、喘憋、肺部啰音及哮鸣音等消失时间均明显短于头孢菌素组、青霉素组(4. 12±0. 56 vs.4. 45±0. 65 vs. 4. 47±0. 70,4. 08±0. 52 vs. 4. 58±0. 56 vs. 4. 59±0. 60,3. 85±0. 45 vs. 4. 32±0. 58 vs. 4. 35±0. 62,3. 78±0. 52 vs.4. 26±0. 62 vs. 4. 28±0. 70) d,(t=2. 029、3. 759、3. 678、3. 408、2. 243、3. 690、3. 749、3. 294,P0. 05);血清TNF-α、IL-6、hs-CRP水平均明显低于头孢菌素组、青霉素组[(7. 31±1. 42 vs. 8. 11±1. 46 vs. 8. 24±1. 51) pmol/L,(116. 58±17. 37 vs. 126. 47±20. 13 vs. 129. 30±20. 48) pg/ml,(50. 25±7. 14 vs. 58. 67±7. 50 vs. 61. 28±8. 63) ng/L](t=2. 256、2. 137、4. 671、2. 577、2. 721、5. 657,P0. 05);乳酸杆菌、双歧杆菌、肠球菌数量明显低于头孢菌素组、青霉素组,肠杆菌数量明显高于头孢菌素组、青霉素组(8. 86±0. 18 vs. 9. 00±0. 31 vs. 9. 05±0. 27,9. 39±0. 42 vs. 9. 63±0. 38 vs. 9. 72±0. 56,8. 18±0. 42 vs. 8. 56±0. 43 vs.8. 77±0. 56,9. 69±0. 57 vs. 9. 33±0. 52 vs. 9. 24±0. 61) log10n/g,(t=2. 244、2. 434、3. 632、3. 096、3. 364、2. 708、4. 842、2. 680,P0. 05)。结论青霉素、头孢菌素均是治疗新生儿感染性肺炎的有效药物,联合用药能迅速缓解感染性肺炎新生儿炎症状态,改善临床症状,但对患儿肠道正常微生态环境的影响也随之加大。 相似文献
3.
《职业卫生与应急救援》2000,18(4):223
(按汉语拼音字母顺序排列) A 癌物理、化学因子诱癌模型及其剂量-效应相关模式.王玉民, 尤占云韦志康,等.⑴:1-3. 国际"妇女健康:职业、癌症和生殖"会议概况.王兰. ⑵:111-112. 安全上海市建筑业安全生产存在问题和对策探讨.朱靳良, 朱陶扣.⑶:115-118. B 苯乙醇、甲苯、苯对骨髓造血的联合毒作用.夏昭林,金锡鹏, 凌诒萍,等.⑵:59-61. 铂铂病1例报告与分析.曹春燕,朱景田.⑷:215. 苯乙烯苯乙烯聚苯乙烯联合装置劳动卫生学评价.董定龙.⑷: 211-212. C 尘肺 20例铁红尘肺的临床观察和动态分析.周梅荣,李世成, 秦小梅.⑴:49. 尘毒加强现场尘毒治理,改善劳动作业环境. 叶涤秋.⑶:158. 参考值上海化工系统健康职工血清ALT活力水平参考值范围的 探讨.陆新华,金惜雯,沈国芳,等.⑵:72-73. D 电磁场工频电磁场对机体脑血流动力学影响的观察.施达, 王佩琪.⑴:23. 电击伤一起电击伤事故的调查与分析.郑玉向.⑶:133. 对二氯苯对二氯苯"三致"作用的研究现状.李明.⑴:27-28. 对二氯苯急性毒性的实验研究.李明于朝贵李永林等. ⑷:178-180. 对二氯苯致癌性研究进展.王兰.⑷:198-199. E 二硫化碳长期接触低浓度二硫化碳对工人健康的影响.汪根盛, 傅慰祖,项翠琴,等.⑷:174-177. F 氟工业氟暴露对机体血清微量元素和过氧化氢酶的影响研究. 郭海燕,李克俊,高华,等.⑶:122-124. 放射某石化企业放射工作人员健康状况分析.孙健.⑴:40-42. 粉尘车间空气中聚氯乙烯粉尘卫生标准的研究.张涛,赵志刚, 王自齐.⑷:187-188. G 汞职业性汞接触对肾小管毒作用的探讨.朱玉华,曹钟兴, 钱龙华,等.⑴:12-14. 口服和肌肉注射二巯基丙磺酸钠驱汞效果的观察.金鑫. ⑴:15-16. 汞齐配制工周围性瘫痪一例报道.管继如,钱天鸿.⑶:165. 三例慢性汞毒性肾病综合征患者的护理.杨萍,石颖.⑷: 215-216. 镉重复性注射镉金属硫蛋白致小鼠肾脏的急性损害. 逄兵, 金泰 ,蒋学之.⑷:171-173. 管理赴美考察"化学品管理技术"情况简介.孙维生.⑵:78-80. 美国化工企业的化学危险品管理.特邀通讯员.⑵:84. 石油化工企业现场射线探伤作业的监督管理对策.郭成华. ⑶:145. 危险化学品登记注册管理规定.国家经贸委.⑷:195. 上海市化学危险物品生产安全监督管理办法.上海市人民政 府.⑷:196-197. 浅谈预防性放射卫生监督管理的基本做法与体会.孙秀玲, 王连生,王启珍,等.⑷:212-213. 工伤职工工伤后的心态及对策.朱江才.⑶:138. 工伤事故的监测、预防和控制.夏昭林,杨富,刘强,等. ⑷:183-186. 心病自拟"冠脉汤"治疗冠心病49例疗效观察.李士吉.⑴:55. 工效学人体工效学原理在实际工作中的应用.任雪峰,金如峰, 夏昭林.⑶:130-133. 工作要点国家经贸委2000年安全生产工作要点.国家经贸委. ⑴:24-25. 《2000年化工安全卫生工作要点》.国家石油和化学工业 局.⑴:25-26. 中华预防医学会化工分会2000年工作要点.中华预防医学 会化工分会.⑴:26. 骨关节炎用液压扩张补充疗法治疗骨关节炎的探讨.张小达, 葛京华.⑵:73. H 化学事故化学事故应急救援抢救系统建设与发展的思考. 施卫祖,崔慕 .⑵:57-58. 化学事故应急医疗救援模式探讨.金永才,阮会良.⑶:157. 化学事故现场应急准备和处置.上海市民防办核化事故应急 救援工作站.⑷:169-170. 环氧乙烷关于"南京12.1特大环氧乙烷泄漏事故"的应急救援报 告.张琳.⑷:207. J 健康昊天公司开展健康监护10年调查报告.郑玉向.⑵:95-96. 20例伽玛刀作业人员5年健康状况的动态观察.刘波, 张仲元,王铁英.⑷:190-191. 一氧化碳对作业工人健康的慢性影响.吴红.⑷:209-210. 急救综合医院创伤急救网络的建设与实践.濮文虎,诸维祥. ⑷:193. 甲硝唑甲硝唑注射液在化脓性腹腔手术中的应用.王玲.⑷:205. L 氯氯气对作业工人肺功能的慢性影响.刘玉红,张蓉娟, 刘福春,等.⑴:17-20. 沥青公路建设中沥青混凝土搅拌场污染状况的调查.陈思元, 胡宗裕.⑶:159. 蔺草蔺草加工业劳动卫生学调查.周承来,徐来荣,马磊,等. ⑷:181-182. 化氢一起氯化氢气体外漏致居民群体吸入反应事件的调查. 王家福,张永林.⑴:42. 流行病生物标志物在职业流行病学研究中的应用.任爱国.⑴: 51-52;⑵:108-110. 生殖职业流行病学在职业卫生研究中的应用.庞琳.⑶: 166-168;⑷:220-222. N 农药异稻瘟净农药生产现场劳动卫生学调查.郑永祥,马之一, 黄菊香,等.⑶:160-161. P 皮肤异噻唑啉酮所致职业性接触性皮炎1例报告.储蕙, 夏宝凤.⑴:43-44. 一起环氧树脂致变应性接触性皮炎的调查报告.张迅, 蔡青,王福平.⑵:99. 对甲苯磺酰氯致接触性皮炎一例报告.都本希高珂.⑶:164. 铍病 16例慢性铍病临床分析(附2例误诊报告).彭娟娟, 王飞云,周泽深.⑵:102-103. Q 铅铅对神经细胞通透性、钙分布及微管、微丝的影响.阮素云, 顾祖维,项翠琴,等.⑴:9-11. 铅吸收者驱铅前后血压和血红蛋白的变化.徐健,段志, 黄奇松,等.⑴:21-22. 铅神经毒作用机理研究的新进展.徐晓辉,袁东,叶舜华. ⑶:146-148. 汽油尿视黄醇结合蛋白测定在汽油作业肾损害研究中的应用. 周金兰.⑶:125-127. S 死因 291例石棉厂职工的死因和生存年限分析.王志红, 周泽深,胡一本,等.⑶:139-141. 烧伤特大面积热水泥烧伤的救治体会.章祥洲,闻建范,杨蔚, 等.⑶:151-152. 虎杖液治疗烧烫伤体会.陶福生,黄朝银.⑷:170. 复方儿茶酊治疗小面积化学性烧伤临床分析.戚峰.⑷:219. 生物限值我国作业环境空气中有害物质容许浓度与职业接触生物 限值.刚葆琪,张忠义.⑴:37-39;⑵:92-94. 三氯乙烯一例三氯乙烯致大疱性表皮坏死松解症的护理.谭琳. ⑶:163. 四氯化碳四氯化碳致肝硬化一例临床分析.石颖,杨萍,蔡洁. ⑷:206. T 探伤石化企业工业探伤人员生物学效应初步观察.王剑, 付迎春,张海川.⑵:75-76. W 微波微波作业人员健康的动态观察.郭九吉,朱玉华,曹钟兴, 等.⑵:62-64. 外伤工业性外伤的调查报告.尉康岭,郝成信.⑵:76-77. 维生素三种维生素作为职业保健食品的简介.王忠康.⑴:56. 危险源重大危险源等级、评估和定级方法介绍.李一.⑷:217-219. X 血流速度 731例脑动脉血流速度关联性因素的探讨.朱利华.⑶: 155-157. Y 异物气管、支气管异物救治体会.李芳林,陈曦.⑴:53-54. 腰痛穴位注射治疗腰痛病例1 500例报告.葛银根,倪秀萍, 陈伟达.⑷:177. 引文分析《职业卫生与应急救援》近五年引文分析.陈图文, 卢仁仁,余顺得.⑵:106-107. Z 中毒还原型谷胱甘肽对急性百草枯中毒治疗作用的实验研究. 刘丽娜,赵金垣,丁丽华,等.⑴:4-8. 窒息性气体急性中毒的救治经验.虞孝里,李思惠.⑴:29-31. 34例硫化氢中毒临床分析.杨敏艳,马福云,戚树型.⑴: 31-32. 3例慢性重度苯中毒的教训.管继如,叶蓉,谢小敏.⑴: 32-33. 急性丙烯腈中毒救治的经验教训.徐丽丽.⑴:34-35. 一起硫酸二甲酯和N-甲基吡咯混合中毒事故报告.胡晨智. ⑴:35-36. 一起急性二氧化硫中毒死亡事故分析.任碧光.⑴:36. 急性有机磷农药中毒反跳原因的探讨.蒋建国.⑴:44. 慢性重度丙烯酰胺中毒致小脑萎缩1例报告.倪志远, 崔淑君,倪霏.⑴:45. 大面积氢氟酸灼伤合并急性重度氟中毒1例报告.王招兄, 王莹,金永才.⑴:46-47. 急性重度一氧化碳中毒合并多脏器功能衰竭1例报告. 晏晖.⑴:48. 灭多威中毒的救治体会.丁萍.⑴:50. 三氯氧磷中毒时雾化吸入辅助治疗护理体会.魏景妹.⑴:54. "生物──化学战剂"中毒的医疗救援.赵杰,朱明学, 黄顺根,等.⑵:65-67. 毒理学研究与中毒急救.周志俊.⑵:68-71. 常州市1988~1999年职业中毒发病情况分析.施玉兴.⑵:74. 有机磷杀虫剂中毒临床研究进展.黄金祥.⑵:81-84. 浅谈救治急性化学中毒病人时的医护配合.闻建范,金文玮. ⑵:85-86. 维生素C防治急性有机磷中毒心脏损害的临床观察.朱志云, 陆也福.⑵:86-87. 急性一氧化碳中毒迟发性脑病46例临床分析.吕智尉.⑵:88. 52例急性职业中毒原因分析.丁邦梅.⑵:89. 一起氢氟酸灼伤合并急性中毒事故调查及教训.马福云, 罗进斌,王晓红,等.⑵:91. 四氯化碳中毒防护的探讨附3例报告.陈海珍,谢兰兰, 王佩丽,等.⑵:100. 急性二氯甲烷重度中毒1例报告.杨渤生,洪一飞,林航. ⑵:101. 急性氮氧化物中毒3例报告.施建俐,高萍.⑵:103. 急性重度硫化氢中毒一例心肌血清标志酶临床观察.施达, 高珂.⑵:104-105. 职业性正己烷中毒4例临床分析.卞红霞,夏玉静.⑵:105- 106. 急性群体化学中毒事故应急救援的经验和教训.王莹.⑵: 113-114. 117例急性化学物中毒致多脏器功能失常综合征(MODS) 临床分析.金雯蓉,李思惠.⑶:134-136. 一起急性苯中毒死亡事故报告.李继猛.⑶:136. 合肥市三县农药中毒情况调查.褚勇,崔高飞.⑶:144. 一起急性硫化氢中毒事故调查.陈丽明,宋健成.⑶:148. 高压氧在急性化学中毒抢救中的临床应用附9例临床分 析.马爱平,李思惠.⑶:149-150. 慢性汽油中毒的护理体会.叶雨婷.⑶:150-151. 11例急性硫化氢中毒抢救护理体会.王代红.⑶:152. 浅议急性职业中毒事故的预防和控制.胡炯,宋健成.⑶:153. 一起工地打桩急性二氧化碳中毒事故调查报告.卢启冰, 张耀宗.⑶:154. 急性香蕉水中毒救治体会(附二例报告).田媛.⑶:127. 急性有机磷农药中毒伴低钾血症60例临床分析.高夫海. ⑶:162. 一起急性重度甲酚中毒事故简报.杜艳菊,杨嘉琦.⑶:124. 一起急性四氯化碳中毒事故调查分析.邢文.⑶:封3. 浅谈常见急性鼠药中毒.王小珍.⑶:168. 急性有机磷农药中毒阿托品化判断通用标准中有关问题的 探讨.陈爱民.⑷:194. 急性氨中毒318例临床分析.李艳萍,王晓辉,张立仁,等.⑷: 200-203. 阿托品在有机磷农药中毒抢救中的运用.王世梅,吴红涛, 胡秀丽.⑷:204-205. 24例急性环氧乙烷中毒的急救与护理.金明珠.⑷:207-208. 抢救急性重度光气中毒1例体会.施玉兴.⑷:208. 82例急性氯气中毒临床分析.曹雪梅.⑷:213-214. 慢性溶剂汽油中毒二例.唐国富.⑷:216. 婴儿急性有机磷中毒8例简报.鲍秀敏,支洪波.⑷:210. 噪声高压氧治疗噪声性听损的实验研究. 王国山, 何冬宁, 徐锡坤,等.⑶:119-121. 低超标噪声危害的调查分析.尉康岭,郝成信.⑶:128-129. 噪声性听力损伤听性脑干反应的观察. 陈珂忠, 杨利民. ⑶:137-138. 生产性噪声对工人听力影响的调查.韦丽姣.⑷:189. 职业影响 4起集装箱货运业职业影响的分析及预防对策.周敏, 许西元,秦景香.⑵:90-91. 职业卫生工矿企业职业卫生现状分析及思考.贾明山.⑵:97. 建立企业职业卫生保健机制的思考与对策.郭九吉, 曹钟兴.⑷:192-193. 职业危害自动连续化硫酸二甲酯生产工艺职业危害预防与污染水 平分析.张伟,张德恩,隋海东,等.⑵:98-99. 模糊聚类与职业危害作业的群体划分.徐信文.⑶:142-143. 相似文献
4.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
5.
《社区医学杂志》2006,(14)
1.急性下壁心肌梗死最易合并A.实性早搏B.房室传导阻滞C.心房颤动D.房性心动过速E.右束支传导阻滞2.导致急性心肌梗死患者早期(24小时内)死亡的主要原因为A.心力衰竭B.心源性休克C.心律失常D.心脏破裂E.肺栓塞3.不能用于判断急性心肌梗死后溶栓成功的临床指标为A.胸痛缓解B.心电图示ST段下降C.频发的实性早搏D.CK-MB峰值前移E.窦性心动过速4.主动脉瓣中度狭窄时瓣口面积为A.<0.75cm2B.0.75~1.0cm2C.1.1~1.75cm2D.1.76~2.0cm2E.2.1~4.0cm25.主动脉瓣反流时心尖部可存在A.Graham-Stell杂音B.Austin-Flint杂音C.Duroziez征D.Tra… 相似文献
6.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
7.
新疆不同民族食管癌血浆代谢组学差异分析 总被引:1,自引:0,他引:1
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
8.
新疆不同民族食管癌血浆代谢组学差异分析 总被引:1,自引:0,他引:1
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
9.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
10.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
11.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
12.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
13.
Objective To investigate the metabonomic variation between patients with esophageal cancer (EC) and healthy controls, and to analyze the variation between patients with EC. Methods 1H-MR and orthogonal partial least-squares discriminant analysis (OPLS-DA) was performed on 108 plasma specimens from EC patients and 50 health controls, and the metabonomic variation between patients with EC and healthy controls analyzed. Results OPLS-DA analysis might correctly separate all plasma specimens from health controls and patients with EC ,leucine(0. 0043±0. 0006,0. 0040±0. 0006) ,alanine(0. 0039±0. 0007,0. 0033±0. 0006), isoleucine (0. 0067±0. 0010,0. 0063±0. 0009), valine (0. 0037±0. 0005,0. 0035±0. 0006) ,glycopretein(0. 0123±0. 0043,0. 0102±0. 0022), lactate(0. 0342±0. 0113,0. 0258±0. 0085), acetone (0. 0027±0. 0023,0. 0017±0. 0008), acetate (0. 0007±0. 0001,0. 0006±0. 0001),choline(0.0035±0.0006, 0.0029±0.0007), isobutyrate (0.0020±0.0004, 0.0018±0.0003),unsaturated lipid (0. 0072±0. 0013,0. 0059 + 0. 0018), VLDL (0. 1209±0. 0589,0. 0879±0. 0269), LDL (0. 0885±0. 0328,0. 0785±0. 0288), 1-methylhistidine(O. 0005±0. 0001,0. 0004±0. 0005)decreased in EC patient' s plasma with statistical significance (r total>0. 27, P<0. 05), dimethylamine (0. 0004±0. 0001,0. 0005±0. 0001), α-glucose (0. 0079±0. 0013,0. 0081±0. 0016), β-glucose (0. O139±0. 0024,0. 0142±0. 0029) ,citric acid (0. 0044±0. 0008,0. 0106±0. 0058) increase in the EC patient's plasma (r total<-0. 27 ,P<0. 05). There were clear variation between Han and Kazak patients,alanine(0. 0031±0. 0005,0. 0029±0. 0004), glutamine (0. 0010±0. 0001,0. 0009±0. 0001), tyrosine (0. 0009±0. 0001,0. 0008±0. 0001), 1-methylhistidine (0. 0005±O. 0001,0. 0004±0. 0001) increased in the Han patients (r>0. 35, P>0. 05), carnitine (0. 0028±0. 0006) was higher in Kazak patients than in Han patients (0. 0025±0. 0004), which had statistical siginificance (r=-0. 40, P<0. 05). Unsaturated lipid (0. 0059±0. 0018,0. 0047±0. 0011), isoleucine (0. 0062±0. 0011,0.13058±0. 0007), alanine (0.0032±0. 0007, 0. 0028±0. 0004) ,glycoprotein (0. 0096±0. 0019,0. 0086±0. 0011) ,glutamine (0. 0011±0. 0001,0. 01309±0. 0001) ,tyrosine(0. 0009±0. 0001, 0. 0008±0. 0001), 1-methylhistidine (0. 0005±0. 0001, 0. 0004±0. 0001)were increased in Uygnr patients as compared with Kazak patients, having statistical significance (r>0. 33 ,P<0. 05), carnifine (0. 0027±0. 0005) was higher in Kazak patients than in Uygur patients (0.0025±0.0004)(r=-0.36,P<0.05). Conclusion The results indicate that1H-MR spectra of plasma analyzed by OPLS-DA statistical methods might completely separate the EC patients from health controls. The metabonomic approach should be helpful in screening of EC patients. 相似文献
14.
15.
《健康大视野》2006,(1):52-53
R综合性医药卫生 1.中华医学杂志2.第四军医大学学报3.北京大学学报.医学版 4.第二军医大学学报5.第三军医大学学报6.解放军医学杂志 7.中国医学科学院学报8.复旦学报.医学版9.同济医科大学学报 (改名为:华中科技大学学报‘医学版) 1 0.白求恩医科大学学报(改名为:吉林大学学报.医学版) 1 1.湖南医科大学学报(改名为:中南大学学报.医学版) 1 2.华西医科大学学报(改名为:四川大学学报.医学版) 1 3.第一军医大学学报14.苏州医学院学报(改名为:苏州大学学报.医学版) 1 5.广东医学16.上海医学17.军事医学科学院院刊18.上海第二医科大学学报 19.… 相似文献
16.
17.
《中国实用乡村医生杂志》2007,14(7):61-62,51
第五单元输血A1题型1.健康成人一次失血量不超过多少毫升可通过人体的代偿使之逐渐恢复而不用输血A.300mL B.500mL C.800mL D.1000mL E.1500mL2.以下哪项不是输血的禁忌证A.充血性心力衰竭B.急性肺水肿C.恶性高血压D.严重感染E.肾功能衰竭3.下列哪种成分最适合需要多次输血而有发热的贫血病人A.浓缩红细胞B.全血C.冷冻红细胞D.少浆血E.洗涤红细胞4.大量输注库存血后引起的并发症不包括A.溶血反应B.高血钾症C.氨中毒D.肺梗死E.心律紊乱5.下列哪项不是输血后发热反应的原因A.配制的血液保存液不纯B.受血者有过敏体质C.采血输血用… 相似文献
18.
李进 《中国卫生质量管理》1996,3(2):23-24
本文提出与我国卫生质量管理极为相关的二十个关键因素:1.制度因素;2.政策因素;3.现实因素;4.战略因素;5.实施因素;6.领导因素;7.质效因素;8.人才因素;9.科学因素;10.教育因素;11.文化因素;12.思想因素;13.变革因素;14.理论因素;15.技术因素;16.长远因素;17.整体因素;18.目标因素;19.控制因素;20.标准因素。 相似文献
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《中国实用乡村医生杂志》2006,13(12):63-64
A4型题(题44~49)患者,男,18岁。早晨起床洗脸照镜子时,出现右眼不能闭合,口角左歪、流涎,四肢活动良好。44.最可能的诊断是A.腮腺炎B.面神经炎C.动眼神经麻痹D.格林-巴利综合征E.脑肿瘤45.不引起类似表现的病变是A.脑梗死B.格林-巴利综合征C.中耳炎D.脑肿瘤E.腮腺炎46.急性期治疗应首选A.电刺激B.维生素C.糖皮质激素D.抗生素E.手术47.如果患者左眼也闭合不全,面部表情动作消失,伴四肢无力,则最可能的诊断是A.腮腺炎B.面神经炎C.动眼神经麻痹D.格林-巴利综合征E.脑肿瘤48.如患者伴有左侧上下肢无力,则病变位于A.右面神经B.脊神经根… 相似文献