多囊卵巢综合征基础治疗的中医药临床研究进展

多囊卵巢综合征（polycystic ovary syndrome PCOS）是常见的妇科内分泌紊乱性疾病,目前病因尚不明确,临床表现异质性,治疗采取对症治疗的原则,从基础治疗、促排卵和并发症治疗三方面着手,而基础治疗又是恢复排卵、治疗并发症的基础.研究显示中医药对于多囊卵巢综合征基础治疗具有良好的疗效.文章对近5年中医药治疗多囊卵巢综合征的主要临床研究进行了概括.     

针灸治疗多囊卵巢综合征的临床观察及护理体会

目的观察针灸治疗多囊卵巢综合征的疗效及护理体会。方法将39例符合多囊卵巢综合征的患者采用针刺方法治疗,观察其月经周期,月经色、质、量及血清性激素的变化。结果临床总有效率达到76.9%。结论针灸治疗多囊卵巢综合征具有安全,副作用小等特点,病人易于接受,是临床上应该广泛开展的治疗项目。     

针灸理疗治疗多囊卵巢综合征临床观察

目的：探讨针灸理疗结合现代辅助技术治疗多囊卵巢综合征（PCOS）的临床疗效。方法：将84例多囊卵巢综合征患者随机分为实验组和对照组两组,每组各42例。实验组患者进行针灸理疗,对照组患者进行常规治疗,比较两组患者的治疗效果。结果：治疗12周后,实验组患者痊愈12例（28.6％）,对照组痊愈4例（9.5％）,差异具有统计学意义（P＜0.05）;实验组患者总有效率为83.3％,显著高于对照组的52.4％（P＜0.05）,差异具有统计学意义。结论：采用针刺理疗治疗PCOS疗效优于常规治疗,能有效改善患者月经周期、经量,提高受孕率,具有较好的临床应用价值。     

针灸治疗多囊卵巢综合征的临床研究概况

多囊卵巢综合征是一种生殖功能障碍与糖代谢异常并存的内分泌紊乱综合征,其病因至今尚无统一结论,目前多囊卵巢综合征的治疗已成为研究热点,针灸作为绿色疗法具有其独特的疗效和优势,近年来针灸治疗对多囊卵巢综合征的研究也越来越多,现就近5年来针灸对多囊卵巢综合征的各种疗法进行总结归纳,并提出思考。     

针灸治疗多囊卵巢综合征的优势与前景

概述针刺、灸法、电针、针药联合等不同针灸方法治疗多囊卵巢综合征的临床研究现状,并探讨其研究设计中的问题与方法,以期优化治疗方案,提高临床疗效。     

补肾活血片治疗多囊卵巢综合征临床研究

认为本病的病变机理是肾－天癸－冲任轴的平衡关系失调，肾虚是致病之本，多兼有痰血瘀阻、肝胆郁热。以补肾为主，兼活血化痰通络、疏肝清热为治疗原则，研制了补肾活血片治疗本病，并与克罗米芬做对照。结果：治疗组３５例中，治愈１８例，有效１４例，无效３例，总有效率为９１．４３％；对照组３５例，治愈１２例，有效１６例，无效７例，总有效率８０．０％。治疗组疗效明显优于对照组（Ｐ＜０．０１），治疗组妊娠率、月经周期恢复正常率均明显高于对照组。     

针灸治愈多囊卵巢综合征1例

<正>患者,孙某,女,24岁,无性生活史,因"停经2月余"于2013年8月29日前来就诊。患者自幼月经周期不规律,时常出现月经后期,5/30~60d。7年前始逐渐不能自主行经,需依赖间隔进行雌、孕激素序贯法(即人工周期)来维持行经,服药期间可有正常月经,药停经停,近5年逐渐出现形体的发胖。2013年4—6月连续做了3个周期的雌、孕激素序贯法,末次月经2013年6月15日,经量适中,色黯淡,质清稀,月经第1d有小腹的冷痛。2013年8月     

针灸治疗肥胖型多囊卵巢综合征的临床疗效观察

目的：观察针灸治疗肥胖型多囊卵巢综合征的临床疗效。方法：将40例符合肥胖型多囊卵巢综合征患者根据中医辨证为脾肾阳虚、痰湿阻滞型,采用针刺加隔药灸治疗,观察其体重（BW）、体重指数（BMI）、腰臀比值（WHR）、空腹血糖（FPG）、空腹胰岛素（FINS）、胰岛素敏感指数（ISI）和相关性激素睾酮（testosterone,T）、雌二醇（estradiol, E）及黄体生成素（luteotropic hormone, LH）/卵泡刺激素（follicle stimulating hormone, FSH）比值的变化。结果：临床总有效率为82.5%,BW、BMI、WHR、T及LH/FSH值均有显著降低（P〈0.01）,E有显著升高（P〈0.01）,FINS也有一定程度降低,ISI则有所升高（P〈0.05）。结论：针灸治疗肥胖型多囊卵巢综合征具有较好的疗效。     

针灸治疗多囊卵巢综合征研究进展

多囊卵巢综合征（ polycystic ovary syndrome,PCOS）是育龄妇女最常见的内分泌代谢紊乱性疾病之一,以慢性无排卵和高雄激素血症为特征,临床发病率高达5％～10％［1］,且青春期少女患此病的趋势正在不断上升［2］。中医古籍中无PCOS这一病名记载,但根据其临床表现多将其归属于月经过少、月经后期、闭经、不孕、癥瘕等范畴［3］。针灸疗法是中医学传统特色疗法,临床采用针灸治疗PCOS方面已取得显著疗效,现将近年来研究进展综述如下。     

温针灸治疗多囊卵巢综合征30例疗效观察

目的:观察温针灸治疗多囊卵巢综合征的临床疗效.方法:将多囊卵巢综合征58例随机分两组,对照组28例采用常规针刺治疗,治疗组30例采用温针灸治疗.结果:两组愈显率与总有效率治疗1个疗程后组间比较,差异无统计学意义(P＞0.05):治疗2个疗程和3个疗程后组间比较,差异均有统计学意义(P＜0.05,P＜0.01).结论:温针灸治疗多囊卵巢综合征疗效优于常规针刺疗法.     

CLINICAL STUDY ON CLIMACTERIC SYNDROME TREATED WITH AURICULAR PLUS BODY ACUPUNCTURE

Aim: To search for the best therapeutic method for climacteric syndrome. Methods: A total of 190 cases of climacteric syndrome participants were randomly divided into auricular plus body acupuncture group (treatment group, n = 96) and simple body acupuncture group (control group, n = 94). Serum sexual hormone (FSH, LH and E2) and blood lipid (TC, LDL-C, HDL-C and TG) levels were detected before and after treatment. Results: After 30sessions of treatment, the total effective rates of treatment and control groups were 82.29% and 76.02% respectively, with the former being significantly higher than the later ( P ＜ 0.01 ). In comparison with pre-treatment of each group, serum follicle-stimulating hormone (FSH) and luterotropic hormone (LH) levels lowered significantly; serum estradiol (E2) increased remarkably ( P ＜ 0.05 - 0.01 ); serum high-density l ipoprotein-cholesterol (HDL-C) of two groups raised significantly ( P＜ 0.05- 0.01 ), and Iow-density lipoprotein (LDL)-C of treatment group decreased evidently (P＜ 0.05). In addition, the improvement of complaints of hot flushes, sweating, paresthesia, insomnia and emotional irritability in treatment group is significantly better than that of control group. Conclusion: Auricular acupuncture combined with body acupuncture has a better therapeutic effect than that of simple body acupuncture in the treatment of climacteric syndrome.     

固本祛邪法治疗小儿慢性鼻渊的临床体会

作者经过多年的临床实践认为，小儿慢性鼻渊之本，当责肺脾两虚，营气血难地上布鼻窍，鼻窍失养，加之肺虚难以祛邪外出，邪毒易于滞留，致鼻渊日久绵绵不愈。２、慢性鼻渊之标，常因风热痰湿，痰湿与风迷邪存在着间接的因果关系，湿痰内阻、鼻窦失宣，致风热之易于滞留，因此，风热痰湿之间是互为因果，相互为病。３、慢性鼻渊之治，主以固本０祛邪，本病病理特点本虚标实，固本祛邪是治疗本病大法，作者常用疏风清热法、清热化痰法     

CLINICAL ANALYSIS TO 74 CASES OF MENOPAUSAL SYNDROME TREATED WITH SIMPLE FIRE NEEDLE

In this paper,simple fire needle pricking the points of Du（Governor）and Ren（Conception）meridians was employed to treat 74 cases of menopausal syndrome.The result showedthat 41 cases were clinically cured,17 markedly improved,15 improved and 1 ineffective,with thetotal effective rate 87％.With the advantages of extensive materials used,simple manipulation andlarge variety of indications,this method is worthy to be popularized.     

丹红注射液联合硫酸镁治疗早发型重度子痫前期的临床研究

目的:观察丹红注射液联合硫酸镁在早发型重度子痫前期治疗中的作用及对妊娠结局的影响.方法:采用开放前瞻病例对照研究,对86例早发型重度子痫前期(孕28 ～ 32周)患者,按入院顺序分为联合组和对照组,对照组43例采用硫酸镁治疗方案,联合组43例在硫酸镁治疗基础上加用丹红注射液,治疗前后均检测血液流变学的各项指标、D-二聚体变化,并比较妊娠结局.结果:联合组明显延长孕周;胎儿窘迫发生明显减少;新生儿死亡明显减少;以上两组比较,均有明显差异(P＜0.05).联合组血液流变学指标的改善也优于对照组,血浆D-2聚体水平明显下降;对照组治疗前后比较差异均无统计学意义.研究中未发现与使用药物等治疗有关的不良反应.结论:联合应用丹红注射液和硫酸镁治疗早发型重度子痫前期,可改善血液的高凝状态,延长孕周,改善围产结局,降低孕妇并发症发生及新生儿死亡率.     

CLINICAL STUDY ON TREATMENT OF CERVICAL SPONDYLOTIC SYNDROME WITH BEETLE NEEDLE

The authors treated 68 cases of cervical spondylotic syndrome with beetle nee-dle,a new needle apparatus(made by themselves)which is not inserted into the skin of the humanbody.A total of 15 sessions of treatment were given to every patient.Results showed that 56 cases(82％)were cured,7 cases(10.3％)improved and 5 cases(7.4％)invalid.Just as its name implies,the beetle is instead of acupuncture needle.All the diseases being able to be treated with acupunctureneedle could also be treated with beetle needle.In addition,the beetle needle therapy has no violentpain,is safe,effective and easy to be popularized. It also has no harm to viscerae,no cross infection,no dangers of broken needle and of failing during treatment,so,the patient needs not to be in fear.The therapy is preferable for patients to accept.     

辨证与辨病相结合治疗高血压病

高血压病属祖国医学眩晕、头痛等病的范畴。以肝风内动、上扰清窍为其主要病机。本文所述多为第二期高血压病,以头晕、头痛、头胀、耳鸣、眼花、失眠、颈项板紧等为主要临床表现,分肝阳上亢、阴虚阳亢、肝肾阴虚、痰浊上扰、血淤痰阻和肾阳虚衰等六型辨证论治,均获良好疗效。     

BRAIN FUNCTIONAL MAGNETIC RESONANCE IMAGING STUDY OF DIARRHEA TYPE OF IRRITABLE BOWEL SYNDROME TREATED WITH MOXIBUSTION AND PLACEBO MOXIBUSTION

Objective: Moxibustion treatment for diarrhea type of irritable bowel syndrome(D-IBS) has exact clinical effects.D-IBS patients show intestinal hypersensitivity.The efficacy mechanism of moxibustion treatment for D-IBS may be implicated during brain functional magnetic resonance imaging(fMRI).Methods: fMRI was performed in 6 female and 9 male patients with D-IBS in moxibustion treatment group and 6 female and 7 male patients in placebo moxibustion group during rectal balloondistension before and after the treatments.Rectal pain was scored before and after the treatments.Results: The first sensation threshold had no difference between 2 groups.Defecation urge threshold increased significantly in moxibustion group after treatment(P0.01) while no changes occurred in placebo moxibustion group after treatment.Pain detection threshold increased significantly in moxibustion group after treatment(P0.01) and increased in placebo moxibustion group but without statistical significance.The rectal pain score beneath 50 mL rectal balloon distention in both groups had no changes before and after the treatments.100 mL distention in moxibustion group decreased after treatment while no changes occurred in placebo moxibusition group.There was no definite area activated beneath 50 mL rectal balloon in both groups before treatment.After treatment, prefrontal cortex(PFC) was affected in moxibustion group, and prefrontal cortex and cingulated cortex(CC) were affected in placebo moxibustion group.Beneath 100 mL rectal balloon distention, activated area(PFC and CC) decreased in moxibustion group after treatment but didn't decrease in placebo moxibusiton group.Conclusion: The rectal sensitivity of D-IBS decreased after moxibustion treatment.The mechanism of the effect of the moxibustion on D-IBS may relate with the decreased sensitivity of the rectum.     

针药结合治疗绝经后骨质疏松症的临床研究

目的:观察针药结合治疗绝经后骨质疏松症的临床疗效.方法:150例绝经后骨质疏松症患者随机分成针药结合组、电针对照组和药物对照组,3组样本各50例.针药结合组予电针刺激结合罗盖全胶丸口服治疗;电针对照组给予电针治疗;药物对照组给予罗盖全胶丸口服治疗;各组均治疗6个月后进行疗效评定.结果:3组治疗后疼痛评分、骨密度、24小时尿Ca/Cr值、E2指标均较治疗前明显改善(P<0.05),针药组改善优于两个对照组(P<0.05或P<0.01).结论:针药结合治疗绝经后骨质疏松症疗效显著.     

足底外侧楔形垫治疗膝骨性关节炎合并膝内翻的临床研究

为探讨膝骨性关节炎合并膝内翻的有效治疗方法。将55例患者（72个患病膝关节），随机分为足底矫形垫组与对照组进行对照观察。经4～6个月随访，临床疗效评定治疗组优良率为9.96％，有效率为82.93％；对照组优良率为6．46％，有效率为35．48％。治疗组中X线影像分级Ⅱ级者疼痛评分及综合评分改善明显（P〈0．05），有显著性差异；Ⅲ级者有改善，但P〉0．05，无显著差异；Ⅳ级患者症状无改善。对照组Ⅱ、Ⅲ、Ⅳ级治疗前后疼痛评分及综合评分均无明显改变。说明足底外侧楔形垫是治疗膝骨性关节炎合并膝内翻的有效方法。     

参麦联合米力农治疗难治性心力衰竭的临床研究

目的:观察参麦联合米力农对难治性心力衰竭患者心功能、NT-proBNP、cTnT的影响.方法:100例难治性心力衰竭患者在采取常规治疗基础上加用米力农和参麦注射液,比较治疗前后心功能、NT- proBNP、cTnT的变化.结果:治疗前后LVEF、CO、VE/VA、LVEDD、NT-proBNP、cTnT的变化均有统计学意义(P均＜0.05).结论:参麦联合米力农治疗难治性心力衰竭有效,有一定的临床价值.