ULTRASTRUCTURAL OBSERVATIONS ON THE FORMATION AND METABOLISM OF CALCAREOUS CORPUSCLES IN CYSTICERCUS CELLULOSAE

目的：在超微结构水平研究猪囊尾蚴石灰小体的形成和代谢。方法：透射电镜。结果：石灰小体的形成可分成两个阶段：细胞内形成阶段和细胞外代谢阶段。石灰小体是在一种细胞内形成的，我们称为成石灰小体细胞。在形成的早期，石灰小体以分泌颗粒的形式出现在细胞内。随着石灰小体的发育，小体呈珠粒和板层样。此时，成石灰小体细胞胀大且细胞器消失。最后，小体聚集成致密黑色背景的颗粒，而成石灰小体细胞的核和细胞器全部消失。在一个成熟的成石灰小体细胞内有１－３或１０－２０个石灰小体。然后，小体释放到实质组织，随着代谢的消耗逐渐呈同心圆样的板层结构和空泡结构。结论：石灰小体是在一种细胞内形成，在实质组织的代谢过程中被消耗。     

STEPWISE REGRESSION ANALYSIS OF FACTORS AFFECTING LIFEQUALITY OF PATIENTS WITH CHRONIC FILARIASIS

通过山东晚期丝虫病人生命质量的评价，我们发现不仅病人的生命质量综合指数而且躯体、心理、社会健康指数也明显地低于健康对照。为改善病人生命质量，促进其康复，我们用逐步回归分析的方法对可能影响病人生命质量的因素进行了分析，筛选出了共同影响着病人生命质量的因素，包括病人的家庭地位、医疗需要、社会交往、家庭关怀、痛苦程度、劳动能力、家庭收入、医疗费用、婚姻状况、病态心理。针对这些可干预因素，我们提出了社会干预措施。     

DETECTION OF MINIMAL RESIDUAL DISEASE IN CEREBROSPINAL FLUID OF ADULTS WITH ACUTE LEUKEMIA BY IMMUNOFLUORESCENCE ASSAY

To detect the minimal residual disease in cerebrospinal fluid of adults with acute leukemia and compare it with cytology examination.Methods The double color monoclonal antibodies of CD45 combined with other distinctive lineage antigens and FCM were used.Results 4 samples of the total 40 CSF specimens from 17 adult patients with acute leukemia in CR were discordance between the results of morphologic and immunologic examination ( approximately 10%). In discordant cases, the results of immunologic investigations appeared to be more informative than that of morphologic examination in predicting residual disease in CSF and diagnosis of CNSL.Conclusion We recommend that the method should be employed to achieve more timely and accurate diagnosis of CNSL in cases with acute leukemia especially when morphologic findings are equivocal.     

EFFECTS OF PHENOBARBITAL ON HYPERBILIRUBINEMIA IN 28 PATIENTS WITH ICTERIC VIRAL HEPATITIS B

To observe the effects of Phenobarbital on hyperbilirubinemia in patients with icteric viral?hepatitis.Methods Sixty-two patients with viral icteric hepatitis B were randomly divided into two groups: Phenobarbital group received orally phenobarbital 90rag daily (30mg tid) for 2 to 4 weeks in addition to 60mg before sleep, if itch presented in night, plus liver-protective drugs; control group received only liverprotective drugs.Results Therapeutic efficacy of phenobarbital group was significantly better than that of control group(Hc=4.035, P<0.05) particularly in eliminating serum bilirubin and alleviating itch. Synchronized decrease of serum ALT and bilirubin occurred. No obvious side-effects were observed but rash occurred in one case.Conclusion Phenobarbital is safe and efficacious in treating hyperbilirubinemia.     

IS TOLOSA--HUNT SYNDROME A LIMITED FORM OF WEGENER'S GRANULOMATOSIS? REPORT OF TWO CASES WITH ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES

Two patients with recurrent painful ophthalmoplegia due to granulomatousinvolvement of the intracavernous sinus (Tolosa-Hunt syndrome)had circulating anti-neutrophil cytoplasmic antibodies witha granular cytoplasmic immunofluorescence pattern during a flare-upof the disease. The presence of these antibodies suggests thatTolosa-Hunt syndrome might be regarded as a localized form ofWegener's granulomatosis. KEY WORDS: Tolosa—Hunt syndrome, Wegener's granulomatosis, Anti-neutrophil cytoplasmic antibodies     

EVALUATION OF VENTRICULAR REPOLARIZATION TIME IN PATIENTS WITH BUNDLE BRANCH BLOCK AND COMPARISON OF TWO FORMULAS FOR CORRECTION OF JT INTERVAL FOR HEART RATE

Objective To evaluate the effects of prolongation of the QRS time on QT interval and seek for a proper formula for correction of the JT interval for heart rate.Methods QRS and QT intervals were measured in 68 patients with bundle branch block (BBB) and 50 normal control subjects.The JT interval was derived by subtracting QRS from QT interval (JT= QT-QRS).The QTc was obtained by applying Bazett's formula(QTc = QT/(RR)~(1/2)).The JTc was obtained by using JTc = JT/(RR)~(1/2) + QRS/(RR)~(1/2)-QRS ( F1 ) and JTC = JT/(RR)~(1/2) (F2)respectively.Results The patients with BBB have a prolonged QTc interval but a normal JTc interval. The JTc obtained by applying F( was significantly different from that obtained by applying F2 ·The curve corresponding to F1 was parallel to the curve defined by Bazett's formula, but the curve corresponding to F2 was not.Conclusion Formula JTc = JT/(RR)~(1/2) + QRS/(RR)~(1/2)-QRS is a better equation than JTc = JT/(RR)~(1/2) for correcting JT interval for heart rate corresponding