生存质量评价在角膜移植手术前后的应用

角膜移植术是治疗角膜盲的主要方法,生存质量作为一种较全面体现新的健康观和医学模式的评价体系已引入眼科领域,能更全面地反映疾病对患者的影响,是传统视功能评价方法的有益补充.角膜疾病对患者生存质量可产生不同程度的影响,而角膜移植术对于不同患者的生存质量具有不同的改善作用.本文主要对生存质量评价的相关知识以及生存质量测定在角膜疾病和角膜移植术后的应用情况进行综述.     

Ophthalmic plastic surgical skills assessment tool

PURPOSE: To present a structured tool to assess ophthalmic plastic surgical skill and to determine its face and content validity. METHODS: A 1-page structured subjective evaluation form was developed to evaluate a resident's oculoplastic surgical skill while performing lateral tarsal strip surgery. The tool consisted of generic task components and global indices evaluated using a 5-point Likert scale. A survey was conducted among a panel of highly experienced oculoplastic surgeons to establish face and content validity of the tool. All feedback was considered and, if feasible, was used to amend the tool. RESULTS: There was more than 90% agreement among the highly experienced oculoplastic surgeons regarding the content and weighting of each assessment component. The final format of the tool is divided in 9 task-specific indices, based on the lateral tarsal strip procedure, and 9 global indices which, after assessment, appraisal, and amendment by our expert panel, demonstrates face and content validity. CONCLUSIONS: The Ophthalmic Plastic Surgical Skills Assessment Tool is a structured, quantitative instrument designed to aid in the oculoplastic surgical evaluation and training of residents.     

Ophthalmic complications of slit-ventricle syndrome in children

OBJECTIVE: To present the ophthalmic features and visual prognosis of patients with slit-ventricle syndrome (SVS). DESIGN: Observational case series. PARTICIPANTS: Six patients diagnosed and treated with SVS at the Montreal Children's Hospital between 1985 and 1999. METHODS: Patients were included in this study if they had an appropriate ophthalmologic follow-up and if they fulfilled the criteria for the diagnosis of SVS based on intracranial pressure monitoring and neuroimaging studies. MAIN OUTCOME MEASURES: Features studied included patients' baseline ophthalmologic evaluation, visual outcome, and neurosurgical characteristics. RESULTS: The follow-up ranged from 1 to 14 years. The average number of shunting procedures was 3.7. Ocular examination performed on the initial visit revealed a normal visual acuity in four patients, esotropia in three of six patients, and nystagmus in two of six patients. Cycloplegic refraction was normal in all the subjects. Initial funduscopic evaluation revealed optic atrophy in a 4-month-old infant, whereas two children developed optic atrophy later in the course of the disease. One child developed severe visual field defects. The two children with optic atrophy had moderate to severe loss of visual acuity associated with SVS. CONCLUSIONS: A prompt recognition of patients with SVS is crucial, because these individuals are at an increased risk for significant visual loss.     

Tissue crossmatch before corneal transplantation

AIM: To investigate the influence of anticorneal antibodies on the outcome of transplantation in recipients before penetrating keratoplasty. METHODS: 100 consecutive penetrating keratoplasties performed between July 1995 and June 1996 were included in this study. Donor corneoscleral rim cryosections were incubated with recipient serum. Fixation of recipient IgM on donor corneas was revealed with a polyclonal anti-human mu-chain antibody. The mean follow up time was 61 months. Five years after transplantation, 63% of patients were available for follow up. During the follow up period, 15% of keratoplasties failed because of irreversible rejection. RESULTS: Anti-donor stromal lamellae IgM were found in 14 recipients. Anti-donor keratocyte IgM were present in 28 recipients. Dilution of recipient serum (up to 1/800) did not modify the results of positive crossmatch assays. Crossmatch assays performed with positive recipient sera and negative donor corneoscleral rims were negative. No significant influence of IgM crossmatch results on graft survival and rejection-free graft survival was found. CONCLUSION: Donor specific anticorneal stroma IgM were found in 28% of recipients before transplantation. This pre-immunisation was not associated with a higher risk of transplantation rejection.     

Ophthalmic injuries in children involved in all-terrain vehicle crashes

PURPOSE: To describe the spectrum of ophthalmic injuries in children involved in all-terrain vehicle (ATV) crashes. METHODS: We retrospectively reviewed the medical records of a level 1 children's trauma center to identify cases with ICD-9 codes pertaining to crashes involving ATVs and cross-referenced for ophthalmic trauma. From these cases, we documented the nature of the crash, patient's age, ophthalmic injuries received, and length of hospitalization. RESULTS: Twenty children, 5 to 16 years of age (mean, 11.1 years), involved in ATV crashes were admitted between June 1997 and April 2002. One was riding with an adult and 3 with other children; 16 were operating the vehicles alone at the time of their crashes. None was wearing a helmet, and all had head trauma. Nine patients had ophthalmic injuries, including lacerations of the eyelid (n = 5), orbital fractures (n = 9), and traumatic optic neuropathies (n = 2). The latter two had final visual acuities of count fingers and no light perception. The average length of hospitalization was 6.6 days. CONCLUSIONS: Ophthalmic trauma is a frequent complication of ATV crashes involving children. Injuries may range from minor lacerations to complex orbital fractures; visual loss may be severe. We believe that the age of the vehicles' operators and their failure to wear protective helmets contribute to the severity of injuries.     

Ophthalmic features and management outcomes of 30 children having Goldenhar syndrome

To study the ophthalmic clinical profile and the management outcomes of children having Goldenhar syndrome (GS). Retrospective review of included children