共查询到19条相似文献,搜索用时 62 毫秒
1.
目的 分析支气管哮喘患者血清降钙素原(PCT)、白细胞介素-33(IL-33)的表达及其与肺部感染发生的相关性。方法 选取于2019年10月-2021年12月收治入院的支气管哮喘患者116例,根据患者是否发生肺部感染分为感染组51例、未感染组65例。检测两组患者血清PCT、IL-33水平。比较两组患者血清PCT、IL-33水平。采用Logistic回归分析法明确影响支气管哮喘并发肺部感染的危险因素。绘制受试者工作特征(ROC)曲线分析血清PCT、IL-33水平对支气管哮喘并发肺部感染的诊断价值。结果 感染组患者血清PCT、IL-33水平均高于未感染组(t=7.433、7.710,P<0.05)。Logistic回归分析显示年龄、血清PCT、IL-33水平是影响支气管哮喘并发肺部感染的危险因素(OR=1.677、2.312、2.094,P<0.05)。ROC曲线分析显示,血清PCT、IL-33水平联合诊断支气管哮喘并发肺部感染的AUC为0.924,高于血清PCT、IL-33水平单独诊断(AUC=0.824、0.846,P<0.05)。结论 血清PCT、IL-33水平异常... 相似文献
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目的 探讨血清B型钠尿肽(BNP)、C反应蛋白(CRP)、降钙素原(PCT)水平对慢阻肺急性加重期(AECOPD)患者并发心力衰竭的预测价值。方法 回顾性收集2021年06月-2023年06月收治的48例住院治疗期间并发心力衰竭的AECOPD患者病历资料为发生组,另收集医院同期收治的住院治疗期间未并发心力衰竭的48例AECOPD患者病历资料为未发生组。对比两组患者基线资料及血清BNP、CRP、PCT等实验室指标,通过受试者工作曲线(ROC)检验血清BNP、CRP、PCT预测AECOPD患者并发心力衰竭的价值。结果 发生组年龄、血清BNP、CRP、PCT水平均显著高于未发生组,差异有统计学意义(P<0.05)。经点二列相关性分析显示,血清BNP、CRP、PCT与AECOPD患者并发心力衰竭间呈正相关(r>0,P<0.05)。绘制ROC曲线,结果显示,血清BNP、CRP、PCT水平单独及联合预测AECOPD患者并发心力衰竭的曲线下面积(AUC)值分别为为0.802、0.740、0.764、0.898,联合预测价值最高。结论 血清BNP、CRP、PCT能较好预测AECOPD... 相似文献
3.
目的:分析成人7型腺病毒感染肺炎与上呼吸道感染患者血清学变化及胸部CT影像学特征。方法:选择某部2019年2-3月突发7型腺病毒感染,出现发热伴咽痛、咳嗽、咳痰、畏寒、头痛等症状患者80例,以胸部CT检查证实肺炎者为观察组(肺炎组)共42例,同期7型腺病毒感染但胸部CT检查未出现病变者为对照组(上呼吸道感染组)共38例。比较两组血常规、C反应蛋白(CRP)、血清降钙素原(PCT)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)等炎症因子水平变化,分析腺病毒肺炎的胸部CT表现。结果:肺炎组CRP、PCT水平显著或非常显著高于上呼吸道感染组(P<0.05,P<0.01);两组白细胞计数、淋巴细胞计数、单核细胞计数及淋巴细胞比例、单核细胞比例均差异不显著(P>0.05),IL-6、TNF-α水平亦差异不显著(P>0.05)。肺炎多肺叶病变亚组CRP、PCT水平显著高于单肺叶病变亚组(P<0.05),白细胞计数显著低于单肺叶病变亚组(P<0.05);两个亚组其他血常规项目及IL-6、TNF-α水平比较,差异不显著(P>0.05)。42例7型... 相似文献
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目的 探讨外周血miR-223、血清胆碱酯酶(ChE)、C反应蛋白(CRP)水平对腰椎骨折内固定术后细菌感染的诊断价值。方法 选取自2019年10月至2020年10月北京积水潭医院收治的35例腰椎内固定术后感染患者为研究对象,并将其纳入B组。选取同期行腰椎骨折内固定术后未发生感染的35例患者纳入A组。术后3 d采集两组患者空腹静脉血,检测血清miR-223、ChE和CRP水平。应用受试者工作特征(ROC)曲线下面积(AUC)评价血清miR-223、ChE和CRP预测术后感染的效能。结果 B组共培养分离病原菌42株,其中革兰阳性菌31株(73.81%),革兰阴性菌11株(26.19%)。B组患者术后3 d外周血miR-223、CRP水平均高于A组,ChE水平低于A组,两组比较,差异均有统计学意义(P<0.05)。miR-223、ChE、CRP三者联合预测术后感染的AUC分别大于miR-223、ChE和CRP单独预测术后感染的AUC(Z=2.887、3.779、3.598,P<0.05)。miR-223、ChE、CRP三者联合诊断预测术后感染的特异度、准确度均高于miR-223... 相似文献
5.
目的 探讨降钙素原(procalcitonin,PCT)在血流感染中的预测价值。方法 回顾性分析2015年6月1日—2017年2月28日期间就诊于西安市第一医院210例患者同时送检血液培养和PCT检测、血细胞分析及C反应蛋白(C-reactive protein,CRP)检测的结果。以血培养结果为金标准,分别计算PCT、CRP水平及白细胞(white blood cell,WBC)、中性粒细胞(neutrophil,NEU)计数的灵敏度、特异度、阳性预测值、阴性预测值、约登指数并绘制受试者工作特征曲线。同时分别比较PCT、CRP、WBC、NEU水平及阳性率在血培养阳性组与阴性组之间、革兰阴性菌血流感染(n=39)与革兰阳性菌血流感染组(n=30)之间的差异。结果 PCT的受试者工作特征曲线下面积(0.772)及约登指数(0.48)均高于CRP、WBC及NEU;血培养阳性组PCT、CRP、WBC、NEU水平及阳性率均显著高于阴性组(P<0.05);革兰阴性菌血流感染患者CRP水平显著高于革兰阳性菌血流感染患者(P<0.05),而2组间PCT、WBC、NEU检测结果差异无统计学意义(P>0.05),且2组间PCT、CRP、WBC及NEU阳性率比较差异无统计学意义(P=0.788,P=0.514,P=1.000,P=0.586)。结论 血清PCT检测对血培养结果有较好的预测价值,联合CRP、WBC、NEU等指标可以辅助早期诊断血流感染。 相似文献
6.
目的探讨急性胰腺炎(acute pancreatitis,AP)患者血清降钙素原(procalcitonin,PCT)、中性粒细胞与淋巴细胞比值(neutrophil lymphocyte ratio,NLR)以及尿素氮(blood urea nitrogen,BUN)水平与疾病严重程度的关系。方法收集2014年3月—2018年5月在成都医学院第二附属医院就诊的148例AP患者。所有病例均在入院后完善血生化检查,将患者按照2012亚特兰大分类标准分为轻度急性胰腺炎(mild acute pancreatitis,MAP)、中度急性胰腺炎(moderately severe acute pancreatitis,MSAP)、重度急性胰腺炎(severe acute pancreatitis,SAP)3组。比较3组患者入院后第1天清晨血清PCT、NLR及BUN水平,使用受试者工作特征(receiver operating characteristic,ROC)曲线评价血清PCT、NLR及BUN水平预测轻度、中度、重度AP的效力。使用Ranson评分对患者进行病情评估。结果SAP组血清PCT、NLR、BUN水平及Ranson评分高于MAP组、MSAP组,且MSAP组上述指标高于MAP组,差异比较具有统计学意义(P<0.05);SAP组住院天数多于MAP组、MSAP组,MSAP组住院天数多于MAP组(P<0.05);Pearson相关分析结果显示血清PCT、NLR、BUN水平均与Ranson评分得分显著正相关((r=0.48,P<0.05;r=0.62,P<0.05;r=0.40,P<0.05);ROC曲线分析表明PCT、NLR、BUN 3者联合评估轻度、中度、重度AP的AUC分别大于PCT和BUN单项(P<0.05),与NLR差异比较无统计学意义(P>0.05)。结论血清PCT、NLR、BUN水平均与AP病情严重程度呈正相关,且对轻度、中度、重度AP预测具有一定价值,3者联合应用对评估AP病情严重程度具有较好的早期预测价值。 相似文献
7.
目的 探讨血清C反应蛋白(C-reactive protein,CRP)及降钙素原(procalcitonin,PCT)对小儿急性阑尾炎诊断价值。方法 实验组选取96例武警兵团指挥部医院普外科确诊为急性阑尾炎的小儿患者,对照组选取同一时期来院体检的56名健康儿童,分别检测2组患者血清CRP、PCT、中性粒细胞比例(NEUT%)及白细胞计数(WBC)水平,并对实验组CRP和PCT的特异性、敏感性进行统计分析。结果 实验组血清CRP(27.73±6.77)mg/L、PCT(1.78±0.86)μg/L、NEUT%(80.63±10.35)%及WBC(14.20±3.21)×109/L含量均显著高于对照组的(4.17±1.36 )mg/L、(0.43±0.76)μg/L、 (63.45±7.3)%、(9.07±3.59)×109/L,两组比较差异具有统计学意义 (P<0.01);分型不同的阑尾炎组间血清CRP和PCT水平比较,差异有统计学意义(P<0.05);实验组患者血清CRP诊断敏感性、特异性分别为88.5%、71.9%,PCT的诊断敏感性、特异性分别为85.4%、90.6%,二者敏感性比较差异无统计学意义,但特异性比较差异有统计学意义 (P<0.01)。结论 血清CRP、PCT含量检测对诊断小儿急性阑尾炎有一定的临床价值,尤其是PCT水平对小儿急性阑尾炎诊断有较高的敏感性和特异性,更适合作为判断阑尾炎程度的辅助性诊断指标。 相似文献
8.
目的 分析血清超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、25-羟基维生素D[25(OH)D]水平与患儿上呼吸道感染的相关性。方法 选取我院2022年04月-2023年06月100例上呼吸道感染患儿为研究组,另选取同期200例健康体检儿童为对照组。对比两组入院时及治疗3 d、7 d时血清hs-CRP、TNF-α、25(OH)D及白细胞(WBC)、降钙素原(PCT)水平,并分析其相关性;分析入院时血清各指标联合检测对患儿上呼吸道感染的诊断价值。结果 研究组入院时血清hs-CRP、TNF-α及WBC、PCT水平均高于对照组,血清25(OH)D水平低于对照组(P<0.05);研究组入院时及治疗后血清hs-CRP、TNF-α及WBC、PCT存在显著差异,随治疗时间增加血清hs-CRP、TNF-α及WBC、PCT显著降低(P<0.05);入院时血清hs-CRP、TNF-α与WBC、PCT呈正相关,血清25(OH)D与之呈负相关(P<0.05);入院时血清hs-CRP、TNF-α、25(OH)D水平联合诊断上呼吸道感染的AUC为0.875。结论 血清hs-CR... 相似文献
9.
目的 分析血清淀粉样蛋白A(SAA)、颗粒蛋白前体(PGRN)水平与小儿重症肺炎炎症反应、预后转归的相关性。方法 将恩施土家族苗族自治州中心医院自2020年6月至2021年6月收治的100例轻症肺炎患儿纳入轻症组;将同期收治的100例重症肺炎患儿纳入重症组;将同期的100例健康体检儿童纳入健康组。比较3组的SAA、PGRN、白细胞介素(IL)-6、C反应蛋白(CRP)、降钙素原(PCT)水平;受试者工作特征(ROC)曲线分析重症组SAA、PGRN与IL-6、CRP、PCT的相关性;比较不同预后患儿的SAA、PGRN、IL-6、CRP、PCT水平;分析SAA、PGRN、IL-6、CRP、PCT、SAA联合PGRN对小儿重症肺炎的预测价值。结果 健康组SAA、PGRN、IL-6、CRP、PCT水平低于轻症组和重症组,轻症组SAA、PGRN、IL-6、CRP、PCT水平低于重症组,差异有统计学意义(P<0.05)。重症组SAA水平与IL-6、CRP、PCT水平呈正相关(r=0.812、0.895、0.753,P<0.05);重症组PGRN水平与IL-6、CRP、PCT水平呈正相关... 相似文献
10.
目的:分析降钙素与血清胃蛋白酶原联合检测在萎缩性胃炎并发感染的诊断价值。方法:选择我院2018年1月-2018年12月期间收治的萎缩性胃炎患者54例为研究组,根据是否感染的标准将研究组患者分为感染组和非感染组,另选54例此期间于我院行健康体检的患者为对照组,比较研究组和对照组、感染组和非感染组患者的降钙素与血清胃蛋白酶原水平。结果:治疗前研究组血清降钙素水平明显高于对照组,PG水平明显低于对照组,差异均有统计学意义(P<0.05),治疗后,研究组血清降钙素水平明显降低,PG水平明显上升,较治疗前均有统计学意义(P<0.05),对照组患者数据较治疗前无明显变化(P>0.05)。且感染组患者的降钙素水平在治疗前明显高于非感染组,PG水平明显低于非感染组(P<0.05),在治疗后,两组数据均有明显改善。结论:降钙素和胃蛋白酶原与萎缩性胃炎合并感染病症存在相关性,在萎缩性胃炎合并感染病症的诊断和治疗中具有重要的意义。 相似文献
11.
目的探讨急性肾衰竭(ARF)时D-二聚体(D-D)、纤溶酶原激活物抑制物(PAI)在不同的血液净化方法中的动态变化及临床意义。方法对我院2007年1月—2010年3月急诊住院58例ARF患者血液净化前、净化后4 h及38例健康人进行血浆中D-D含量及PAI水平测定。ARF患者血液净化方法随机采用血液透析(HD)(31例)、血液透析滤过(HDF)(27例)。结果 ARF患者D-D含量及PAI水平较对照组明显升高[D-D(0.83±0.04)与(0.48±0.03)mg/L,P=0.000 2;PAI(14.95±0.73)与(8.03±0.30)103kat/L,P<0.0001;]HD治疗4 h后D-D含量和PAI活性较治疗前升高[D-D(0.89±0.05)与(1.48±0.37)mg/L,P=0.018;PAI(14.89±1.78)与(22.10±3.56)103kat/L,P=0.025],而HDF治疗后D-D含量和PAI无明显变化[D-D(0.91±0.06)与(1.12±0.09)mg/L,P=0.65;PAI(15.81±1.98)与(16.10±2.56)103kat/L,P=0.86]。结论 ARF患者D-D、PAI水平升高,存在凝血-纤溶系统的紊乱,HD可以加重这种改变,而采用HDF治疗可避免对患者凝血机能的影响,在急性肾衰竭治疗中有一定临床价值。 相似文献
12.
Yabuuchi H Fukuya T Murayama S Sakai S Okamura J Fukuda T Tomita K Ro T Masuda K 《Clinical radiology》2002,57(3):205-210
AIM: To clarify CT and MR features of nasopharyngeal carcinoma (NPC) in children and young adults. METHOD: CT and MR findings of 13 patients (30 years old or younger) with a histopathologic diagnosis of NPC were reviewed. RESULTS: Skull base invasion (12/13), lymphadenopathy (10/13), and infiltrative growth (8/8) were common findings. The signal intensity of tumours was slightly higher than that of muscles in six cases and isointense to that of muscles in two cases on T1-weighted images; it was higher than that of muscle and lower than that of cerebellar grey matter on T2-weighted images in all cases. Internal signals were homogeneous in both pre- and post-Gd-enhanced MR images in all cases. CONCLUSIONS: Despite its rarity in this age group, NPC should be included in a differential diagnosis when CT and MR imaging reveal these features. 相似文献
13.
Takanori Hara Katsuhiro Ichikawa Shigeru Sanada Yoshihiro Ida 《European journal of radiology》2010,75(1):114-121
Objective
The present study was performed to examine the dependence of image quality on in-plane position and direction in computed tomography (CT) imaging using the modulation transfer function (MTF), noise power spectrum (NPS) and analysis of signal-to-noise ratio (SNR). For detailed analysis of SNR, the low-contrast detectability was compared using simulated small low-contrast objects.Materials and methods
Three models of multidetector-row CT (MDCT) were employed. The measurement positions for MTF were set to the isocentre and several peripheral areas, and NPS and SNR were calculated for the isocentre and 128 mm off-centre. To evaluate directional dependence, the one-dimensional physical properties were measured separately in the radial and azimuthal directions. Seven radiological technologists also performed a perceptual detection study at the different in-plane positions using computer-simulated low-contrast images.Results
The results of MTF and SNR differed between the isocentre and the peripheral area. The MTF values also tended to decrease with distance from the isocentre, and the SNR values in the low frequency range for the peripheral area were superior to those for the isocentre. In the detection study, the low-contrast detectability in the peripheral area was 13-40% higher than the value in the isocentre.Conclusion
The results of the present study indicated that clinical CT images have remarkable non-uniformity of image quality. Therefore, the detailed analysis performed in this study will provide useful information for the development of advanced image processing applications, such as computer-aided diagnosis (CAD) and de-noising of CT images. 相似文献14.
目的:观察高压氧(HBO)辅助治疗对卒中后抑郁(PSD)患者血清5-羟色胺(5-HT)、去甲肾上腺素(NE)及神经功能的影响。方法70例PSD患者根据数字表法随机分为2组,对照组(n=35例)采用常规措施治疗,观察组(n=35例)待确定活动性出血已稳定或已趋于稳定后,在对照组治疗基础上加用HBO治疗。两组疗程均为30d,比较两组患者治疗前后血清5-HT、NE表达水平及汉密尔顿抑郁量表(HAMD)、中国脑卒中量表(CSS),改良Barthel指数(MBI)评分变化。结果两组患者治疗后血清5-HT、NE表达水平均明显升高(P<0.05),且观察组升高较对照组更为显著(P<0.05);两组患者治疗后HAMD、CSS评分明显降低(P<0.05),而MBI评分明显升高(P<0.05),且观察组降低或升高较对照组更为显著(P<0.05)。结论 HBO辅助治疗可明显升高PSD患者血清5-HT、NE表达水平,改善抑郁状态和神经功能。 相似文献
15.
Juna Musa Masum Rahman Abu Bakar Siddik Kristi Saliaj Samar Ikram Ina Kola Alireza Shoushtarizadeh Ali Guy Inva Mamica Abdur Rahman Eram Ahsan Anisa Cobo Ruben Blanco 《Radiology Case Reports》2021,16(11):3176
Parsonage-Turner Syndrome (PTS), also known as brachial neuritis or neuralgic amyotrophy, is a rare disorder affecting 2 to 3 individuals per 100,000 each year. Abrupt onset shoulder pain, followed by motor weakness, paresthesia and hypoesthesia, is usually reported, lasting several months with variable recovery. The etiology of the disease may be idiopathic or triggered by an underlying autoimmune disease in genetically susceptible individuals. Our report addresses a unique case of Parsonage-Turner Syndrome in a patient suffering from concurrent Hashimoto Thyroiditis. A previously healthy A 22 year-old female was referred to the Department of Neurology after complaints of sudden-onset motor weakness in her left upper limb. On physical examination, the patient could not make an “Ok sign” with her thumb and distal phalanx or form a complete fist, revealing weakness within the anterior interosseous branch of the median nerve. Further testing with electromyography demonstrated muscular atrophy within the arm''s anterior compartment, forearm, and triceps brachii of the posterior compartment. Additional imaging and physical examination were unremarkable, confirming our diagnosis of PTS. Furthermore, lab reports revealed elevated levels of anti-thyroglobulin and anti-thyroid peroxidase antibodies and our patient was concurrently diagnosed with Hashimoto''s thyroiditis.This case aims to highlight the rare co-occurrence of Hashimoto''s thyroiditis with Parsonage-Turner Syndrome in an otherwise healthy patient. A 2014 study published by Nugent et al. had also shed light on brachial neuritis in a patient suffering from autoimmune connective tissue disease, and through this case study, we hope to add to the growing literature regarding the correlation between PTS and autoimmune diseases. Symptoms of PTS can easily be misdiagnosed given its similarity to other peripheral neuropathies, and careful assessment and thorough understanding of the disease is required to successfully distinguish it from other neurological pathologies. 相似文献
16.
递增负荷运动至力竭大鼠肾脏自由基产生及氧化抗氧化能力的研究 总被引:28,自引:1,他引:27
以大鼠增负荷力竭性运动为模型,利用低温电子自旋共振(SER)技术,分别于安静时、运动中、运动后即刻、运动后30min、2h、4h、8h提取大鼠肾组织,测定氧自由基(OFR)信号强度,同时测定SOD活力和MDA含量,结果表明:①运动后恢复期30min,肾脏OFR信号强度升高明显,提示运动性肾缺血及恢复期再灌注诱导的黄嘌呤氧化酶机制可能是肾组织OFR生成的主要来源;②在运动过程中及恢复期OFR改变与SOD变化趋势基本吻合,提示肾内源性SOD在防止OFR损伤中起重要作用;③肾脏MDA于运动后2h出现峰值,而OFR则于恢复期30min升至最高,说明除肾脏自身产生活性氧诱导脂质过氧化以外,其它部位转移的MDA也许占很大比重 相似文献
17.
目的 探讨氧化应激及炎性反应指标在缺血性脑卒中的临床意义。方法 检测缺血性脑卒中(ischemic stroke, IS)患者和健康对照组血清中总抗氧化能力(total antioxidant capacity,TAC)、氧化型低密度脂蛋白(oxidized low density lipoprotein ,Ox-LDL)、超氧化物歧化酶(super oxide dismutase ,SOD)、超敏C反应蛋白(high sensitivity C reactive protein,Hs-CRP)等指标的表达,采用ELISA方法检测血清TAC、Ox-LDL;在贝克曼库尔特AU5821全自动生化分析仪上检测其他指标的水平。结果 (1)治疗组较正常对照组血清中TAC显著性降低,几乎为健康人水平的1/12(P<0.01),高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、SOD的水平有所下降(P<0.05);(2)Hs-CRP 、Ox-LDL、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)的水平显著性升高(均P<0.01),治疗组血清中Hs-CRP约为对照组的16倍,其OX-LDL水平约为1.7倍,LDL-C约为1.6倍。治疗组较对照组血清中氧化应激及炎性反应指标的表达差异有统计学意义。结论 脑卒中的发生可能与氧化应激、炎性反应有重大关系。 相似文献
18.
Eatesam M Noworolski SM Tien PC Nystrom M Dodge JL Merriman RB Qayyum A 《Journal of magnetic resonance imaging : JMRI》2012,35(1):103-109
Purpose:
To compare liver ADC obtained with breathhold and free‐breathing diffusion weighted imaging (DWI) in healthy volunteers and patients with liver disease.Materials and Methods:
Twenty‐eight subjects, 12 healthy volunteers and 16 patients (9 NAFLD, 7 chronic active HCV), underwent breathhold (BH) and free‐breathing (FB) DWI MRI at 1.5 Tesla. Pearson's correlation coefficient was used to determine correlation while paired t‐tests assessed differences between BH and FB ADC. Estimated bias was calculated using the Bland‐Altman method.Results:
Liver ADC (×10?3 mm2/s) was lower on BH for all groups (mean difference 0.36 ± 0.20; P < 0.01). ADC was higher in healthy volunteers (BH 1.80 ± 0.18; FB 2.24 ± 0.20) compared with NAFLD patients (BH 1.43 ± 0.27; FB 1.78 ± 0.28) (P < 0.001) and HCV patients (BH 1.63 ± 0.191; FB 1.88 ± 0.12). Overall correlation between BH and FB ADC was (r = 0.75), greatest in NAFLD (r = 0.90) compared with the correlation in HCV (r = 0.24) and healthy subjects (r = 0.34). Bland‐Altman plots did not show agreement in mean absolute difference and estimated bias between subjects.Conclusion:
Correlation between BH and FB liver ADC is moderate indicating that BH and FB should not be used interchangeably. Additionally, the lower ADC values in BH versus FB should be accounted for when comparing different liver DWI studies. J. Magn. Reson. Imaging 2012;35:103‐109. © 2011 Wiley Periodicals, Inc.19.
RATIONALE AND OBJECTIVES: To evaluate the clinical utility of cranial computed tomography (CT) in pediatric and adult patients during ongoing extracorporeal membrane oxygenation (ECMO) treatment from acute respiratory failure and to assess the frequency of intracranial hemorrhage (ICH) and infarction during the treatment. MATERIALS AND METHODS: The medical records of 123 consecutive patients, 54 children (ages 3 months-17 years) and 69 adults (ages 18-62 years), treated with ECMO over a 10-year period were searched for cranial CT performed during ECMO. Indications for CT, CT findings, impact on clinical management, and patient outcome were noted. In addition, all CT scans were reviewed for the frequency of ICH or infarction. RESULTS: Seventy-eight patients had cranial CT while on ECMO. ICH or cerebral infarction were detected in 45 (37%) of the 123 patients. Eighteen patients (15%) had focal hemorrhage, 11 (9%) focal infarction, and 16 (13%) general brain edema. In 16 of the 45 patients, the CT findings were decisive to withdraw the ECMO treatment. Five patients were weaned from ECMO, and in four patients the findings motivated cranial surgery during ECMO. In the remaining 20 patients with less extended intracranial pathology, the ECMO treatment was continued with high survival. CONCLUSION: Cranial CT has an important role during ECMO treatment to reveal or exclude severe intracranial complications where ECMO treatment should be discontinued. Less severe complications have a favorable prognosis with continued treatment. Our study suggests an underreporting of intracranial complications in adults and pediatric patients on ECMO because of low utilization of neuroimaging. 相似文献